CourseSource: Resources

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Teaching Genetic Linkage and Recombination through Mapping with Molecular Markers

Most introductory genetics courses cover genetic linkage, a core concept in the CourseSource genetics learning outcome framework. Although it is a classical genetics topic, genetic linkage remains an important concept to understand in order to...

Courses: Genetics Plant Biology Science Process Skills

meiosisphenotypegel electrophoresismicrosatellitesBanding PatternGenetic linkageInheritanceMolecular MarkersPhysical Linkage

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6526

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1119

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0

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Mapping a Mutation to its Gene: The "Fly Lab" as a Modern Research Experience

Although genetics is an invaluable part of the undergraduate biology curriculum, it can be intimidating to students as well as instructors: Students must reduce their reliance on memorization and dive deep into quantitative analysis, and...

Courses: Biochemistry and Molecular Biology Bioinformatics Genetics Science Process Skills

geneticsbioinformaticsdrosophilachi-square analysiscomplementation mappingmode of inheritancethree-point mapping

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1482

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158

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Infectious Chocolate Joy with a Side of Poissonian Statistics: An activity connecting life science students with subtle physics concepts

Introductory physics courses are required for many programs in the life sciences, yet traditional curricula fail to help students meaningfully connect physical concepts with biological systems. In this lesson, we describe an activity taught...

Courses: Bioinformatics Microbiology Science Process Skills

quantitative biologyHIVmultiplicity of infectionPoisson DistributionPhysics for biologists

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1882

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639

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A Close-Up Look at PCR

The Polymerase Chain Reaction (PCR) is a fundamental laboratory technique that allows for the amplification of many copies of a desired DNA target sequence. Despite its prevalence, undergraduate students often have poor comprehension about the...

Courses: Biochemistry and Molecular Biology Genetics Introductory Biology Science Process Skills

PCRDNA replication

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1844

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425

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0

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Teaching epidemiology and principles of infectious disease using popular media and the case of Typhoid Mary

Allied health students often struggle to understand how particular content, such as epidemiology, connects to their future careers. This activity uses the case of Typhoid Mary as a foundation for exploring epidemiology and infectious disease...

Courses: Microbiology Science Process Skills

epidemiologycase studyinfectous diseasepopular mediaTyphoid Mary

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1693

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494

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0

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Sex-specific differences in Meiosis: Real-world applications

In traditional classrooms, students are typically presented with facts that they are asked to memorize and recall during an exam. The rapid explosion of available scientific facts in recent years has made this model of teaching...

Courses: Cell Biology Genetics Science Process Skills

meiosisReproductionAneuploidyGameteNon-disjunctionOocyteSpermTrisomy

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3170

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1094

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Squirreling Around for Science: Observing Sciurid Rodents to Investigate Animal Behavior

Hands-on research experiences are important opportunities for students to learn about the nature of inquiry and gain confidence in solving problems. Here, we present an inquiry-based lesson plan that investigates the foraging behavior of sciurid...

Courses: Ecology Ecology Introductory Biology Science Process Skills

foragingbehaviorbehavioral ecologySciuridSquirrelSquirrel-NetTrade-offVigilance

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2561

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641

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Follow the Sulfur: Using Yeast Mutants to Study a Metabolic Pathway

Students are frequently overwhelmed by the complexity of metabolic pathways and they think they have "learned" the pathway when they have memorized the individual reactions. This laboratory lesson helps students to understand the...

Courses: Biochemistry and Molecular Biology Genetics Introductory Biology Microbiology Science Process Skills

SelectionyeastMetabolismcysteinemediamethioninemutantPathwaysulfur

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1692

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518

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A Remote Introductory Biology Lab Using Backyard Birdwatching to Teach Data Analysis and Communication

Asking questions, designing experiments, collecting data and interpreting those data, and communicating the results are some of the most important concepts an undergraduate biology lab can teach students. When the SARS-CoV2 pandemic forced our...

Courses: Ecology Ecology Introductory Biology Science Process Skills

ecologydata analysisdata collection

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3075

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453

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0

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Moths and Frogs and E. coli, Oh My!: Agent-based Modeling of Evolutionary Systems

In evolution classrooms, introducing and reinforcing the idea of genetic drift and random selection can be challenging, as can be reinforcing appropriate mental models of evolution. Agent-based models offer students the opportunity to conduct a...

Courses: Bioinformatics Ecology Ecology Evolution Science Process Skills

modelingEvolutionecologyagent-based modelingGenetic Driftenvironmental scienceNatural Selectioncompetitive coevolutionsimulation modelingevolutionary reasoning

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1678

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184

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Nanoparticles and Shrimp: An Interdisciplinary Lab Series in Chemistry and Biology for Undergraduate Engineering Students

The parallels between engineering and science are vast, as both disciplines apply theory and inquiry to solve complex problems. In order to prepare students for interdisciplinary careers in STEM, we have developed a lab project in which...

Courses: Cell Biology Ecology Ecology Science Process Skills

microscopychemistry applications in biologytoxicity

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703

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Teaching Biodiversity with Museum Specimens in an Inquiry-Based Lab

In response to the growth of biology datasets and broad efforts to digitize data, an increasingly important skill for science students is the management and analysis of large datasets. We designed an inquiry-based lab module to introduce students...

Courses: Ecology Ecology Evolution Introductory Biology Science Process Skills

data analysisnatural historyphylogenyBiodiversitymammalsAllen's RuleBergmann's Ruleecogeographymuseum research

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3580

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505

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How Many Squirrels Are in the Shrubs? A Lesson Plan for Comparing Methods for Population Estimation

Estimating the population sizes of animals is a key skill for any student interested in ecology, conservation, or management. However, counting animals in natural habitats is difficult, and the many techniques that exist each rely on assumptions...

Courses: Ecology Ecology Introductory Biology Professional Development and Career Planning Science Process Skills

population ecologywildlife managementpopulation estimationsciuridaeSquirrel-Net

Teaching Tools and Strategies

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473

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A Strategy for Teaching Undergraduates to Write Effective Scientific Results Sections

Most undergraduate instructors would agree that learning to write about data in the style of a scientific research paper is a worthy goal for their students. However, many hesitate to tackle the challenge of teaching scientific writing in...

Courses: Science Process Skills

data analysisprimary literaturescientific writingcommunicating science

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3345

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618

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Predicting and classifying effects of insertion and deletion mutations on protein coding regions

Mutations in genes can affect the encoded proteins in multiple ways, and some of these effects are counterintuitive. As for any other knowledge, students must create their own deep understanding of the Central Dogma. Students may not develop this...

Courses: Bioinformatics Genetics Science Process Skills

mutationcentral dogmatranslationframeshift

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357

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Interactive Video Vignettes (IVVs) to Help Students Learn Genetics Concepts

Many video resources exist to teach Mendelian genetics, but most consist of passive delivery of information rather than active construction of knowledge by users. We have created two interactive video vignettes (IVVs) that can be used together or...

Courses: Genetics Introductory Biology Science Process Skills

genotypephenotypeallelespedigreedominanceHardy-Weinberg equilibriumInheritance

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394

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Taking the Hassle out of Hasselbalch

Mention pH in a classroom and you can almost see the inner yawn on the faces of your students. The definition may even roll easily from their lips. However, despite multiple exposures to the relationship of pH and pKa throughout a typical...

Courses: Biochemistry and Molecular Biology Science Process Skills

pHdrug uptakeHenderson-Hasslbalch equationmedical applicationspKa

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612

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Using Synthetic Biology and pClone Red for Authentic Research on Promoter Function: Introductory Biology (identifying new promoters)

Students often memorize the definition of a transcriptional promoter but fail to fully understand the critical role promoters play in gene expression. This laboratory lesson allows students to conduct original research by identifying and...

Courses: Genetics Introductory Biology Science Process Skills

bacteriasynthetic biologygene regulationtranscriptionstudent researchcentral dogmacloningpromoterreporter gene/protein

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2045

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Exploration of the Human Genome by Investigation of Personalized SNPs

Students often shy away from tedious bioinformatics approaches to exploring their genomes. However, in our expanding digital world these skills are some of the most relevant and valuable. To increase students' interest in their own genomes, I...

Courses: Bioinformatics Genetics Science Process Skills

UCSC genome browsersingle nucleotide polymorphismGenome wide association studiesGenomic organization

Lesson

2013

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573

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0

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Using Undergraduate Molecular Biology Labs to Discover Targets of miRNAs in Humans

Incorporating authentic research experiences into undergraduate labs, while shown to be particularly effective at engaging and retaining students in STEM majors, can be difficult to accomplish within the constraints of resource availability or...

Courses: Bioinformatics Genetics Science Process Skills

gene regulationmicroRNAsgene expression

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Teaching Genetic Linkage and Recombination through Mapping with Molecular Markers

Mapping a Mutation to its Gene: The "Fly Lab" as a Modern Research Experience

Infectious Chocolate Joy with a Side of Poissonian Statistics: An activity connecting life science students with subtle physics concepts

A Close-Up Look at PCR

Teaching epidemiology and principles of infectious disease using popular media and the case of Typhoid Mary

Sex-specific differences in Meiosis: Real-world applications

Squirreling Around for Science: Observing Sciurid Rodents to Investigate Animal Behavior

Follow the Sulfur: Using Yeast Mutants to Study a Metabolic Pathway

A Remote Introductory Biology Lab Using Backyard Birdwatching to Teach Data Analysis and Communication

Moths and Frogs and E. coli, Oh My!: Agent-based Modeling of Evolutionary Systems

Nanoparticles and Shrimp: An Interdisciplinary Lab Series in Chemistry and Biology for Undergraduate Engineering Students

Teaching Biodiversity with Museum Specimens in an Inquiry-Based Lab

How Many Squirrels Are in the Shrubs? A Lesson Plan for Comparing Methods for Population Estimation

A Strategy for Teaching Undergraduates to Write Effective Scientific Results Sections

Predicting and classifying effects of insertion and deletion mutations on protein coding regions

Interactive Video Vignettes (IVVs) to Help Students Learn Genetics Concepts

Taking the Hassle out of Hasselbalch

Using Synthetic Biology and pClone Red for Authentic Research on Promoter Function: Introductory Biology (identifying new promoters)

Exploration of the Human Genome by Investigation of Personalized SNPs

Using Undergraduate Molecular Biology Labs to Discover Targets of miRNAs in Humans

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