CourseSource: Resources

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Harnessing the Power of the Immune System: Influenza Vaccines

Because most people have been infected by and/or immunized against influenza, students should know how the immune system responds to the infection and how vaccines protect against disease. Vaccines have played an instrumental role in disease...

Courses: Biochemistry and Molecular Biology Immunology Science Process Skills

VaccinesInfluenzaImmunizationVaccine efficacy

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2929

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362

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Bacteria to Brains in Backyard Coyotes: An Interdisciplinary Pedagogical Case Study

Our interdisciplinary pedagogical case study explores the differences between rural and urban coyotes at the levels of organismal and community ecology. The focus is on how coyotes’ gut microbiomes could affect their behavior via...

Courses: Cell Biology Ecology Ecology Evolution Immunology Introductory Biology Microbiology

dietanimal behaviorimmune systemmicrobiomeNervous systemgut-brain axisImmunoReachdysbiosisCoyoteCytokines

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1669

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314

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Understanding Host-Pathogen Interactions With the Use of Galleria mellonella

The Galleria mellonella; the larvae of the Greater Wax Moth, is a safe and effective means to study host-pathogen interactions in the undergraduate setting. The use of animal models in the teaching classroom provides an opportunity to discuss...

Courses: Immunology Microbiology

innate immunitybacterial pathogenesisHost-pathogen interactionsGalleria mellonellaVirulence

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4196

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667

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Design Your Own Flow Cytometry Experiment: A Four-Week Inquiry Laboratory

Due to its importance to the field, flow cytometry should be one of the hallmark methods a student learns in the lab portion of an undergraduate immunology course. Flow cytometry is a classic lab technique utilized within immunology and molecular...

Courses: Immunology

Immunologyexperimental designFlow cytometryMice

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1804

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190

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Inexpensive Cell Migration Inquiry Lab using Zebrafish

Cell migration is an important and interesting topic that has the potential to engage students in cell biology by its intrinsically active nature. However, most ways to investigate cell migration require expensive equipment not typically available...

Courses: Cell Biology Science Process Skills

CytoskeletonCell migrationmodel organisms

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1042

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173

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To Vaccinate or Not to Vaccinate

To vaccinate or not to vaccinate, that is the question. Much of the recent trend in society against vaccination is that the general population does not understand 1) how vaccines work and 2) how one's vaccination status can influence others....

Courses: Anatomy-Physiology Biochemistry and Molecular Biology Introductory Biology Microbiology

pathogenELISAimmunityantibodyAntigen

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1221

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556

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Understanding Gastric Acid Secretion: An Active Learning Approach

The human digestive system is a diverse network of cells, tissues, and organs that is regulated by systemic (e.g., nervous and endocrine systems) and local factors (e.g., secretions, pH, and the microbiome). Given the volume of content and the...

Courses: Anatomy-Physiology

diseasesignal transductionAcid SecretionAutonomic Nervous SystemEndocrineGastric PhysiologyGPCRHistology of Gastric Pit

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1394

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197

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Using Collaborative Projects to Promote Active Learning of Microbial Skin Diseases and Their Impact on Everyday Lives

One of the most daunting aspects of introductory clinical microbiology is learning details about a vast number of different microbial diseases that can infect humans. Each of these diseases has different causative agents, diagnostic procedures,...

Courses: Microbiology

infectious diseasecollaborationpathogenesisTreatment of diseasesReal-life Microbiology

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333

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54

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Using an Interactive Game, Gutsy, to Examine the Impacts of Pathogens and Everyday Events on the Human Gut Microbiome

The human gut microbiome is often associated with ‘good bacteria’ in marketing campaigns for dietary supplements, probiotic drinks, and fermented foods. Yet, the dynamic and complex community of microbes that make up the gut microbiome...

Courses: Anatomy-Physiology Immunology Microbiology

bacteriaGamepathogenhealthmicrobiomediversity

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1514

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210

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Modeling Strep Throat Detection, Infection, and Spread Using an SIR Model and the Vensim Simulation Software

The overarching goal of this lesson is to provide students with an opportunity to gain experience making and using biological models. Biological modeling can be used to investigate complex, real-world problems so that predictions can be made about...

Courses: Cell Biology Immunology Introductory Biology Microbiology

infectious diseasebiological modelingSIR model

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1584

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340

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Real World Scenarios in Non-Majors Biology

Students in non-majors’ biology courses may not choose careers that require biology content knowledge; however, all will encounter science in their lives. We redesigned a non-majors introductory biology course to support students in...

Courses: Introductory Biology Science Process Skills

geneticsVaccinesScientific ProcessGMOsviruses

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2447

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172

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Online Information Literacy: Applying the CRAAP Test to Vaccine (Mis)information

Teaching scientific literacy skills can help combat the propagation of misinformation online. This lesson is intended to give students practice identifying reliable scientific information on the Internet, in the context of vaccine safety. It was...

Courses: Science Process Skills

Vaccinesimmunityreliability

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2091

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288

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Assessing in vivo Antimicrobial Activity Through the Analysis of Galleria mellonella Kaplan-Meier Plots

Antimicrobials and their use in the treatment of bacterial infections are a fundamental lesson in all microbiology courses. Typically, cultivation-based methods are used to teach students about antimicrobial testing. A complementary approach...

Courses: Microbiology

Antimicrobial TestingAntimicrobialsInvertebrate animal models

Teaching Tools and Strategies

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129

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Enhancing the Microscopy Skills of Non-Science Majors and Nursing Microbiology Students: Promoting the Practice of Observing Multiple Fields of View Using Blood Smear Slides

One of the challenges in teaching microscopy is having students scan multiple fields of view at high power magnification. Many times, students will feel this unnecessary, especially when presented with slides that show only one structure or a...

Courses: Introductory Biology Microbiology

Microscopy SkillsBlood SmearsBlood Disorders

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1151

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Using Musical Instruments to Model Negative Feedback in the Hypothalamo-Pituitary-Target Gland Axes

Homeostasis and negative feedback are crucial, yet difficult, concepts for undergraduates, particularly in the context of the hypothalamo-pituitary axes. This interactive activity was designed to (1) reveal how negative feedback can restore...

Courses: Anatomy-Physiology

cell-cell communicationhomeostasisnegative feedback

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Good Drug, Bad Practice: Tackling the Ivermectin Fiasco

Throughout history, biomedical advancements have alleviated suffering worldwide and significantly advanced human well-being. As researchers and educators, we are well-familiar with the painstakingly slow and meticulous process of science, some of...

Courses: Anatomy-Physiology Neurobiology Science Process Skills

Peer reviewCOVID19fraudtherapeutic drugIvermectin

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1694

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285

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Using Comics to Make Science Come Alive

Students often see science as a fragmented set of facts to be memorized, rather than concepts and processes that are relevant in their everyday lives. This is especially true for non-science majors, who represent the vast majority of all college...

Courses: Ecology Ecology Genetics Introductory Biology Neurobiology

role of science in society

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2124

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The impact of diet and antibiotics on the gut microbiome

The goal of this article is to describe an active learning exercise that can be used in a variety of advanced microbiology courses, including bacterial physiology, ecology, or systems biology. The gut microbiome is a multi-species bacterial...

Courses: Microbiology

microbiomeenvironmental controlhost responsemetabolites

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3505

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A CRISPR/Cas Guide RNA Design In Silico Activity

CRISPR biotechnologies inspired by the Clustered Regularly Interspaced Short Palindromic Repeat RNA-guided nuclease adaptive bacterial immune system have revolutionized biology research and become ubiquitous tools for hypothesis and...

Courses: Biochemistry and Molecular Biology Bioinformatics Cell Biology Genetics

bioinformaticsgene expressiongenetic basis of diseaseCRISPR/Cas9genetic engineeringin silico

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2057

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324

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The Inside and Outside the Body

The Inside and Outside the Body activity helps students develop a conceptual understanding of anatomical barriers such as skin and mucus membranes that separate internal cells and fluids from the external environment. This short exercise prepares...

Courses: Anatomy-Physiology

structureAnatomybarriers