CourseSource: Resources

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473

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Why do Some People Inherit a Predisposition to Cancer? A small group activity on cancer genetics

Before undergraduate students take a genetics course they generally know cancer has a genetic basis and involves the proliferation of cells; however, many are uncertain about why only a subset of people have a predisposition to cancer and how that...

Courses: Genetics Science Process Skills

cancerInheritance patternsProbability calculationProto-oncogeneTumor Suppressor Gene

Lesson

6472

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1115

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0

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Mapping a Mutation to its Gene: The "Fly Lab" as a Modern Research Experience

Although genetics is an invaluable part of the undergraduate biology curriculum, it can be intimidating to students as well as instructors: Students must reduce their reliance on memorization and dive deep into quantitative analysis, and...

Courses: Biochemistry and Molecular Biology Bioinformatics Genetics Science Process Skills

geneticsbioinformaticsdrosophilachi-square analysiscomplementation mappingmode of inheritancethree-point mapping

Lesson

1556

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336

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0

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Real World Scenarios in Non-Majors Biology

Students in non-majors’ biology courses may not choose careers that require biology content knowledge; however, all will encounter science in their lives. We redesigned a non-majors introductory biology course to support students in...

Courses: Introductory Biology Science Process Skills

geneticsVaccinesScientific ProcessGMOsviruses

Lesson

3333

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615

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0

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Predicting and classifying effects of insertion and deletion mutations on protein coding regions

Mutations in genes can affect the encoded proteins in multiple ways, and some of these effects are counterintuitive. As for any other knowledge, students must create their own deep understanding of the Central Dogma. Students may not develop this...

Courses: Bioinformatics Genetics Science Process Skills

mutationcentral dogmatranslationframeshift

Lesson

2008

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352

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1

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Interactive Video Vignettes (IVVs) to Help Students Learn Genetics Concepts

Many video resources exist to teach Mendelian genetics, but most consist of passive delivery of information rather than active construction of knowledge by users. We have created two interactive video vignettes (IVVs) that can be used together or...

Courses: Genetics Introductory Biology Science Process Skills

genotypephenotypeallelespedigreedominanceHardy-Weinberg equilibriumInheritance

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3461

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720

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0

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Homologous chromosomes? Exploring human sex chromosomes, sex determination and sex reversal using bioinformatics approaches

Constructing a robust understanding of homologous chromosomes, sex chromosomes, and the particulate nature of genes is a notoriously difficult task for undergraduate biology students. In this lesson, students expand their knowledge of human...

Courses: Bioinformatics Genetics Introductory Biology Science Process Skills

bioinformaticsautosomehomologous chromosomeshomologous recombinationsex chromosomesex determinationsex reversal mutations

Lesson

2031

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889

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0

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Exploration of the Human Genome by Investigation of Personalized SNPs

Students often shy away from tedious bioinformatics approaches to exploring their genomes. However, in our expanding digital world these skills are some of the most relevant and valuable. To increase students' interest in their own genomes, I...

Courses: Bioinformatics Genetics Science Process Skills

UCSC genome browsersingle nucleotide polymorphismGenome wide association studiesGenomic organization

Lesson

1834

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421

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0

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Teaching epidemiology and principles of infectious disease using popular media and the case of Typhoid Mary

Allied health students often struggle to understand how particular content, such as epidemiology, connects to their future careers. This activity uses the case of Typhoid Mary as a foundation for exploring epidemiology and infectious disease...

Courses: Microbiology Science Process Skills

epidemiologycase studyinfectous diseasepopular mediaTyphoid Mary

Lesson

9249

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1199

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0

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Why Meiosis Matters: The case of the fatherless snake

A compelling reason to learn something can make all the difference in students’ motivation to learn it. Motivation, in turn, is one of the key attitudes that drives learning. This story presents students with a compelling puzzle of a...

Courses: Genetics Science Process Skills

meiosismitosissex determinationAsexual reproductionParthenogenesis

Teaching Tools and Strategies

2769

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269

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0

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The Pipeline CURE: An Iterative Approach to Introduce All Students to Research Throughout a Biology Curriculum

Participation in research provides personal and professional benefits for undergraduates. However, some students face institutional barriers that prevent their entry into research, particularly those from underrepresented groups who may stand to...

Courses: Developmental Biology Genetics Introductory Biology Science Process Skills

epigeneticsundergraduate researchmendelian inheritanceSelf-EfficacyCUREsnature of scienceResiliencecurriculum strategiesreprogramming

Lesson

2669

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229

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0

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Role of Crop Genetic Diversity on Pathogen Impact: The Tale of Two Pathogens

Introductory genetics courses are part of the core curriculum in many different fields, including plant breeding, animal science, biology, microbiology, and natural resource management. Concepts involving genes, inheritance, evolution, and genome...

Courses: Introductory Biology Plant Biology Science Process Skills

plant pathologygenetic diversityDisease TriangleModes of Reproduction

Lesson

3369

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1343

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0

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Using the Cell Engineer/Detective Approach to Explore Cell Structure and Function

As instructors of introductory biology courses for majors and non-majors, we have struggled with teaching the concept of cell structure and function in an engaging way. However, this is a foundational concept that most biology instructors...

Courses: Cell Biology Introductory Biology Science Process Skills

cell functionCell StructureCellular diversityDynamic cellular functionOrganelle function

Teaching Tools and Strategies

1147

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343

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0

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Fostering Student to Student Collaboration Across Institutions in a Protein Centric CURE

Collaboration is an essential component of research because it allows scientists to share expertise and tackle difficult scientific questions. While many undergraduate science courses include inquiry-based or authentic research projects,...

Courses: Biochemistry and Molecular Biology Genetics Introductory Biology Professional Development and Career Planning Science Process Skills

communicationBiochemistrycollaborationCUREhypothesisStudent to StudentInter institutionalProtein CentricAssignments

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4825

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1849

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0

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Teaching Genetic Linkage and Recombination through Mapping with Molecular Markers

Most introductory genetics courses cover genetic linkage, a core concept in the CourseSource genetics learning outcome framework. Although it is a classical genetics topic, genetic linkage remains an important concept to understand in order to...

Courses: Genetics Plant Biology Science Process Skills

meiosisphenotypegel electrophoresismicrosatellitesBanding PatternGenetic linkageInheritanceMolecular MarkersPhysical Linkage

Teaching Tools and Strategies

1850

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382

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0

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Converting a Face-to-Face Lab to Online: An Example of Process and Outcomes for a CRISPR-Based Molecular Biology Lab

The COVID-19 pandemic created a need to convert in-person laboratory courses into an online format in a short amount of time. For this reason, we converted our face-to-face molecular biology lab course to an online version in Spring 2020. The lab...

Courses: Genetics Science Process Skills

mutationtranscriptioncrisprtranslation

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1677

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492

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Sex-specific differences in Meiosis: Real-world applications

In traditional classrooms, students are typically presented with facts that they are asked to memorize and recall during an exam. The rapid explosion of available scientific facts in recent years has made this model of teaching...

Courses: Cell Biology Genetics Science Process Skills

meiosisReproductionAneuploidyGameteNon-disjunctionOocyteSpermTrisomy

Teaching Tools and Strategies

2318

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189

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A Pandemic Pivot: Podcast as an Active Engagement Tool in the Classroom and Beyond

Higher education in STEM undoubtedly integrates the use of technology as a primary mode for content delivery to undergraduate students. This became especially salient throughout the shift to online education during the COVID-19 pandemic. Despite...

Courses: Science Process Skills

VaccinesReplication of virusesCOVID-19 transmission

Lesson

1696

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349

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0

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Chilling in the Cold: Using Thermal Acclimation to Demonstrate Phenotypic Plasticity in Animals

The lesson plan described here provides students hands-on, scientific experiences that relate to the globally important issue of climate change and its impacts on animals. Students use the scientific method and basic components of experimental...

Courses: Ecology Ecology Evolution Science Process Skills

scientific methodclimate changephenotypic plasticityfruit fliesaccclimationcold tolerancethink-pair-share

Review

3557

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280

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0

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Active Learning: Developing Self-Directed Learners Through Strong Intellectual Engagement

When they were students, many current science instructors learned through traditional lectures. This mode of passive knowledge transmission has been shown to be less effective for student learning than an approach that involves students in a...

Courses: Introductory Biology Science Process Skills

active learningmetacognitionconstructivism

Lesson

1083

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191

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0

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Using Current Events to Teach Written, Visual, and Oral Science Communication

Science, technology, engineering and mathematics (STEM) professionals need the skills to communicate with both technical and public audiences, but formal training in these skills is often lacking. In the nine-hour unit presented here, students...

Courses: Science Process Skills

communicationscientific writingstorytellingaudiencecurrent events

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Why do Some People Inherit a Predisposition to Cancer? A small group activity on cancer genetics

Mapping a Mutation to its Gene: The "Fly Lab" as a Modern Research Experience

Real World Scenarios in Non-Majors Biology

Predicting and classifying effects of insertion and deletion mutations on protein coding regions

Interactive Video Vignettes (IVVs) to Help Students Learn Genetics Concepts

Homologous chromosomes? Exploring human sex chromosomes, sex determination and sex reversal using bioinformatics approaches

Exploration of the Human Genome by Investigation of Personalized SNPs

Teaching epidemiology and principles of infectious disease using popular media and the case of Typhoid Mary

Why Meiosis Matters: The case of the fatherless snake

The Pipeline CURE: An Iterative Approach to Introduce All Students to Research Throughout a Biology Curriculum

Role of Crop Genetic Diversity on Pathogen Impact: The Tale of Two Pathogens

Using the Cell Engineer/Detective Approach to Explore Cell Structure and Function

Fostering Student to Student Collaboration Across Institutions in a Protein Centric CURE

Teaching Genetic Linkage and Recombination through Mapping with Molecular Markers

Converting a Face-to-Face Lab to Online: An Example of Process and Outcomes for a CRISPR-Based Molecular Biology Lab

Sex-specific differences in Meiosis: Real-world applications

A Pandemic Pivot: Podcast as an Active Engagement Tool in the Classroom and Beyond

Chilling in the Cold: Using Thermal Acclimation to Demonstrate Phenotypic Plasticity in Animals

Active Learning: Developing Self-Directed Learners Through Strong Intellectual Engagement

Using Current Events to Teach Written, Visual, and Oral Science Communication

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