Skip to Main Content
Powered by QUBES
Text Search:
Applied Filters
    Lesson
    3750

    views

    1244

    downloads

    0

    comments

    My Dog IS My Homework: Exploring Canine Genetics to Understand Genotype-Phenotype Relationships
    To facilitate understanding of the fundamental genetic concept of the genotype-phenotype relationship in our introductory biology students, we designed an engaging multi-week series of related lessons about canine genetics in which students...

    Courses: BioinformaticsBioinformatics GeneticsGenetics Introductory BiologyIntroductory Biology Science Process SkillsScience Process Skills

    gel electrophoresissequence analysiscanine geneticsdeoxyribonucleic acid (DNA)dog coat morphologygenotype and phenotypemutationsPolymerase chain reaction (PCR)single nucleotide polymorphism (SNP)
    Lesson
    3115

    views

    401

    downloads

    0

    comments

    Honoring the Complexity of Genetics: Exploring the Role of Genes and the Environment Using Real World Examples
    Historically, undergraduate genetics courses have disproportionately focused on the impact of genes on phenotypes, rather than multifactorial concepts which consider how a combination of genes, the environment, and gene-by-environment interactions...

    Courses: EvolutionEvolution GeneticsGenetics Introductory BiologyIntroductory Biology

    genesenvironmentMendelQuantitative traitsMultifactorialGene by environment interactions
    Lesson
    3045

    views

    731

    downloads

    0

    comments

    Using Synthetic Biology and pClone Red for Authentic Research on Promoter Function: Genetics (analyzing mutant promoters)
    Students often memorize the definition of a transcriptional promoter but fail to fully understand the critical role promoters play in gene expression.  This laboratory lesson allows students to conduct original research by characterizing...

    Courses: GeneticsGenetics Science Process SkillsScience Process Skills

    bacteriasynthetic biologygene regulationtranscriptionstudent researchcentral dogmacloningpromoterreporter gene/protein
    Lesson
    2247

    views

    301

    downloads

    0

    comments

    Learning Quantitative Genetics: Investigation of Genetic Control for Cold Stress Response in Plants
    Course-embedded undergraduate research experiences (CUREs) for students have been shown to increase students’ understanding of the process of science, affirm their scientific identity, and improve retention in STEM fields. Despite many CUREs...

    Courses: GeneticsGenetics

    data analysisrecombinationplantsquantitative geneticsabiotic stress responsegenetic control of complex traitsinheritance of complex traits
    Lesson
    1995

    views

    352

    downloads

    1

    comments

    Interactive Video Vignettes (IVVs) to Help Students Learn Genetics Concepts
    Many video resources exist to teach Mendelian genetics, but most consist of passive delivery of information rather than active construction of knowledge by users. We have created two interactive video vignettes (IVVs) that can be used together or...

    Courses: GeneticsGenetics Introductory BiologyIntroductory Biology Science Process SkillsScience Process Skills

    genotypephenotypeallelespedigreedominanceHardy-Weinberg equilibriumInheritance
    Essay
    816

    views

    121

    downloads

    0

    comments

    Implementing active learning approaches into an upper-division biology course
    In this essay, we present our strategy for implementing active learning strategies into an upper division course on Human Genetics. Our principal goal was to shift from a traditional didactic course design, to one that more clearly placed the...

    Courses: GeneticsGenetics Introductory BiologyIntroductory Biology

    human biologyPedigree analysisRare genetic diseases
    Lesson
    4793

    views

    1206

    downloads

    1

    comments

    Teaching the Central Dogma Using a Case Study of Genetic Variation in Cystic Fibrosis
    The central dogma of biology is a foundational concept that is traditionally included in genetics curricula at all academic levels. Despite its ubiquitous presence throughout genetics education, students persistently struggle with both the...

    Courses: GeneticsGenetics

    transcriptioncentral dogmatranslationsequence analysisDNA replicationgenetic variants
    Lesson
    1883

    views

    470

    downloads

    0

    comments

    Why do Some People Inherit a Predisposition to Cancer? A small group activity on cancer genetics
    Before undergraduate students take a genetics course they generally know cancer has a genetic basis and involves the proliferation of cells; however, many are uncertain about why only a subset of people have a predisposition to cancer and how that...

    Courses: GeneticsGenetics Science Process SkillsScience Process Skills

    cancerInheritance patternsProbability calculationProto-oncogeneTumor Suppressor Gene
    Lesson
    3086

    views

    894

    downloads

    1

    comments

    Fruit Fly Genetics in a Day: A Guided Exploration to Help Many Large Sections of Beginning Students Uncover the Secrets of Sex-linked Inheritance
    Moving beyond the basic concepts of autosomal Mendelian inheritance to sex-linkage can be difficult for introductory biology students. Although crosses with Drosophila fruit flies have long been a mainstay of genetics units that teach these...

    Courses: GeneticsGenetics

    Mendelian Geneticsfruit fly biologysex-linked inheritance
    Lesson
    6430

    views

    1110

    downloads

    0

    comments

    Mapping a Mutation to its Gene: The "Fly Lab" as a Modern Research Experience
    Although genetics is an invaluable part of the undergraduate biology curriculum, it can be intimidating to students as well as instructors: Students must reduce their reliance on memorization and dive deep into quantitative analysis, and...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology BioinformaticsBioinformatics GeneticsGenetics Science Process SkillsScience Process Skills

    geneticsbioinformaticsdrosophilachi-square analysiscomplementation mappingmode of inheritancethree-point mapping
    Lesson
    3725

    views

    275

    downloads

    0

    comments

    Fragile States: A Case Study Exploring Genetics, Molecular Biology, and Biochemistry Through the Lens of Fragile X Syndrome
    This case aims to strengthen students’ understanding of molecular biology concepts through study of Fragile X Syndrome (FXS). Students begin by learning the cause and phenotypes of FXS and related conditions. Students then apply genetics...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology GeneticsGenetics

    gene regulationtranscriptiontranslationFragile X syndrometriplet repeat expansionsex linkagemetabolic pathway
    Lesson
    2612

    views

    573

    downloads

    0

    comments

    Linking Genotype to Phenotype: The Effect of a Mutation in Gibberellic Acid Production on Plant Germination
    Basic concepts in genetics and plant development are often taught in lecture courses without a lab component. This approach provides students with the content knowledge, but fails to make connections to research opportunities and real-world...

    Courses: Cell BiologyCell Biology Developmental BiologyDevelopmental Biology GeneticsGenetics Introductory BiologyIntroductory Biology Plant BiologyPlant Biology

    geneticsdevelopmentmutationgerminationplantmodel organismGenotype/PhenotypeHormoneSeed
    Teaching Tools and Strategies
    1057

    views

    138

    downloads

    0

    comments

    Casting a Wide Net via Case Studies: Educating across the undergraduate to medical school continuum in the biological sciences
    This article seeks to help bridge undergraduate and medical educators by describing shared educational goals and strategies, highlighting resources relevant for both groups, and exemplifying shared interests through a demonstration resource. Both...

    Courses: GeneticsGenetics

    genetic testingdirect-to-consumer genetic testinginformed consentprenatal screeningsecondary findingswhole genome sequencing
    Essay
    579

    views

    70

    downloads

    0

    comments

    Teaching about fatherless snakes in a prison classroom
    Developing a course for the first time as a graduate student is challenging. When I first taught introductory biology with the Cornell Prison Education Program, I struggled to design and adapt lessons that felt relevant to my students....

    Courses: GeneticsGenetics Introductory BiologyIntroductory Biology

    meiosismitosisReproduction
    Lesson
    2021

    views

    883

    downloads

    0

    comments

    Exploration of the Human Genome by Investigation of Personalized SNPs
    Students often shy away from tedious bioinformatics approaches to exploring their genomes. However, in our expanding digital world these skills are some of the most relevant and valuable. To increase students' interest in their own genomes, I...

    Courses: BioinformaticsBioinformatics GeneticsGenetics Science Process SkillsScience Process Skills

    UCSC genome browsersingle nucleotide polymorphismGenome wide association studiesGenomic organization
    Lesson
    2962

    views

    342

    downloads

    0

    comments

    A Muscular Dystrophy Case Study Illustrating the Phenotypic Effects of Mutation
    Mutations in genes can lead to a variety of phenotypes, including various human diseases. Students often understand that a particular mutation in a single gene causes a disease phenotype, but it is more challenging to illustrate complex genetic...

    Courses: Developmental BiologyDevelopmental Biology GeneticsGenetics

    mutationProtein Structureethicscentral dogmahuman disease
    Lesson
    520

    views

    78

    downloads

    0

    comments

    Using Raw Sequence Data to Analyze Tumor Suppressor Mutations
    Learning to identify DNA sequence variants from raw sequencing data (electropherograms) is a basic molecular biology skill with applications to basic research and clinical practice. Yet learning to map DNA sequence variants to functional regions...

    Courses: BioinformaticsBioinformatics GeneticsGenetics

    bioinformaticsmutationDNAgenomic visualizationparts of a geneclinical consequencesraw data
    Lesson
    3385

    views

    276

    downloads

    0

    comments

    Garden Variety Mutations: Using Primary Data to Understand the Central Dogma in Large-Lecture Introductory Biology
    The ability to interpret and create an argument from data is a crucial skill for budding scientists, yet one that is seldom practiced in introductory courses. During this argumentation module, students in a large lecture class will work in groups...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology GeneticsGenetics Introductory BiologyIntroductory Biology

    mutationtranscriptiongene expressioncentral dogmatranslationgel electrophoresisGenotype/Phenotype
    Lesson
    1673

    views

    491

    downloads

    0

    comments

    Sex-specific differences in Meiosis: Real-world applications
    In traditional classrooms, students are typically presented with facts that they are asked to memorize and recall during an exam.  The rapid explosion of available scientific facts in recent years has made this model of teaching...

    Courses: Cell BiologyCell Biology GeneticsGenetics Science Process SkillsScience Process Skills

    meiosisReproductionAneuploidyGameteNon-disjunctionOocyteSpermTrisomy
    Science Behind the Lesson
    1454

    views

    201

    downloads

    0

    comments

    The Science Behind the ACTN3 Polymorphism
    A common polymorphism in the alpha-actinin-3 (ACTN3) gene results in the lack of ACTN3 protein expression in fast twitch muscle fibers in ~16% of the human population (1). This genetic change has been linked with muscle performance in humans (2)...

    Courses: Anatomy-PhysiologyAnatomy-Physiology GeneticsGenetics

    protein structure and functionhuman genetic variationskeletal muscle physiology