CourseSource: Resources

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Follow the Sulfur: Using Yeast Mutants to Study a Metabolic Pathway

Students are frequently overwhelmed by the complexity of metabolic pathways and they think they have "learned" the pathway when they have memorized the individual reactions. This laboratory lesson helps students to understand the...

Courses: Biochemistry and Molecular Biology Genetics Introductory Biology Microbiology Science Process Skills

SelectionyeastMetabolismcysteinemediamethioninemutantPathwaysulfur

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4967

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The Avocado Lab: An Inquiry-Driven Exploration of an Enzymatic Browning Reaction

Typical biochemistry labs exploring basic enzyme activity rely on costly, time-consuming protein purification and rarely explore enzyme function in situ. Further, complex purification procedures leave little room for novelty in experimental...

Courses: Biochemistry and Molecular Biology Introductory Biology

enzymescontrolsenzyme inhibition

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2812

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769

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Unwrapping Enzyme Kinetics

Enzyme rates and kinetics are key components used by biochemists to understand how enzymes function. However, students often find it difficult to understand how these experiments are performed and how they reflect enzyme behavior in solution. The...

Courses: Biochemistry and Molecular Biology

kineticsstructure-functionenzymescatalysis

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4281

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Evaluating the Quick Fix: Weight Loss Drugs and Cellular Respiration

One key to student success in introductory and cell biology courses is a foundational knowledge of cellular respiration. This is a content area in which students often harbor misconceptions that make cellular respiration particularly challenging...

Courses: Biochemistry and Molecular Biology Cell Biology Introductory Biology

data analysisCellular RespirationElectron Transport ChainEnergy transformationsMitochondriaOxidative phosphorylationWeight loss drugs24-dinitrophenol (DNP)

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5284

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Investigating Enzyme Structure and Function Through Model-Building and Peer Teaching in an Introductory Biology Course

A foundational knowledge of the relationship between structure and function is critical to understanding how enzymes work. The seemingly invisible nature of these molecular interactions makes it challenging for undergraduate students to...

Courses: Biochemistry and Molecular Biology Introductory Biology

structure-functionEnzymeallosteric regulationcompetitive inhibitionfeedback inhibitionnoncompetitive inhibitionproductsubstrate

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8509

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Lights, Camera, Acting Transport! Using role-play to teach membrane transport

Lights, Camera, Acting Transport! is an active and unique role-play exercise designed to teach introductory biology students basic concepts of passive and active membrane transport. The activity involves three acts in which students, representing...

Courses: Biochemistry and Molecular Biology Cell Biology Introductory Biology

ATPcarrierschannelsco-transportelectrogenic pumpfacilitated diffusionmembrane transportpassive transportprimary active transportsimple diffusion

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3695

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Breaking Bricks: A Hands-On Model of Enzyme Kinetics and Inhibition

Enzyme kinetics and the impacts of inhibitors on the enzyme's maximal velocity and ability to bind substrates are important topics in cell biology and biochemistry. However, these topics can be difficult for students to grasp when instructed...

Courses: Biochemistry and Molecular Biology Cell Biology

kineticsEnzymecompetitive inhibition

Teaching Tools and Strategies

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A 360˚ View of COVID-19

In March 2020, institutions underwent a massive transition to distance learning as a result of the COVID-19 pandemic. With so little time to devise new materials to maximize learning in the new virtual environment, instructors devised a variety of...

Courses: Biochemistry and Molecular Biology Bioinformatics Cell Biology Evolution Genetics Immunology Introductory Biology Microbiology Science Process Skills