CourseSource: Resources

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Using Bioinformatics and Molecular Visualization to Develop Student Hypotheses in a Malate Dehydrogenase Oriented CURE

Developing student creativity and ability to develop a testable hypothesis represents a significant challenge in most laboratory courses. This lesson demonstrates how students use facets of molecular evolution and bioinformatics approaches...

Courses: Biochemistry and Molecular Biology Bioinformatics Science Process Skills

bioinformaticsNoncovalent InteractionsEnzyme CatalysisProtein Structure/function

LessonPlus

1459

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306

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Keep It Shrimple: An Adaptable Student-Driven Research Project for the Introductory Biology Laboratory

A challenge in introductory biology laboratory courses is to provide students with authentic, engaging research opportunities that allow them to take ownership of their experiments. We present a nine-week introductory biology module that allows...

Courses: Introductory Biology Science Process Skills

hypothesis testingexperimental designanimal behaviorbrine shrimp

Lesson

619

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39

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0

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Breaking It Down: What Factors Control Microbial Decomposition Rates?

Demonstrating and modeling changes in ecosystem processes in the laboratory classroom can be logistically difficult and expensive. This complexity often leaves little time for students to generate and test hypotheses. Yet, we must foster student...

Courses: Ecology Ecology Microbiology Science Process Skills

data analysishypothesis testingdata visualizationdata managementMicrobial RespirationDecompostionAbiotic ConditionsResults Communication

Lesson

2068

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419

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Antibiotic Resistance Genes Detection in Environmental Samples

Our aim is to provide an authentic research experience for undergraduate students in a variety of biology courses through collaboration between a four-year university and a community college. This lab series teaches transferable and universal...

Courses: Introductory Biology Microbiology Science Process Skills

geneticsenvironmentmicrobiologyUndergraduateantibiotic-resistancePCRgel electrophoresisauthentic inquiry

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2149

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431

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A Short Laboratory Module to Help Infuse Metacognition during an Introductory Course-based Research Experience

A core competency identified in Vision and Change for undergraduate biology students is the Ability to Apply the Process of Science. Here, we describe a three-week laboratory module for students in an Introductory Cell and Molecular Biology...

Courses: Science Process Skills

metacognitiongene expressionScientific ProcessExperimenal DesignHypothesis Generationmodel organisms

Lesson

1456

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315

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0

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Investigating Gene Expression and Cell Specialization in Axolotl Embryos

The process of cell specialization is critical to the formation and function of tissues in animals and plants. Although gene expression, including the regulation of transcription, is taught in most introductory cell biology courses, the...

Courses: Biochemistry and Molecular Biology Cell Biology Developmental Biology Science Process Skills

developmenttranscriptiongene expressionmodel organismembryo

Lesson

1559

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433

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0

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Generating Biological Hypotheses in a "Course-based Undergraduate Research Experience"(CURE) Course

Hypotheses are often incorrectly defined as educated guesses or if/then statements. Further confusion arises from the fact that not all disciplines define hypotheses similarly. The difficulty in distinguishing between statistical and biological...

Courses: Science Process Skills

scientific methodHPT axisNeural stem cells

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8848

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1138

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0

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Why Meiosis Matters: The case of the fatherless snake

A compelling reason to learn something can make all the difference in students’ motivation to learn it. Motivation, in turn, is one of the key attitudes that drives learning. This story presents students with a compelling puzzle of a...

Courses: Genetics Science Process Skills

meiosismitosissex determinationAsexual reproductionParthenogenesis

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2532

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407

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An Introduction to Eukaryotic Genome Analysis in Non-model Species for Undergraduates: A tutorial from the Genome Consortium for Active Teaching

Advances in Next Generation Sequencing (NGS) technology have led to development of many research methods for analyzing genomic data. Students studying biology at the undergraduate level must hone their skills at genomic analysis to participate in...

Courses: Bioinformatics Genetics Science Process Skills

Speciationgenome evolutiongenetic variation

Lesson

1572

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319

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0

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Chilling in the Cold: Using Thermal Acclimation to Demonstrate Phenotypic Plasticity in Animals

The lesson plan described here provides students hands-on, scientific experiences that relate to the globally important issue of climate change and its impacts on animals. Students use the scientific method and basic components of experimental...

Courses: Ecology Ecology Evolution Science Process Skills

scientific methodclimate changephenotypic plasticityfruit fliesaccclimationcold tolerancethink-pair-share

Lesson

1552

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283

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0

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Bad Cell Reception? Using a cell part activity to help students appreciate cell biology, with an improved data plan and no loss in coverage

With a veritable myriad of cell parts to cover, it is easy for educators to become locked into marathon presentations that become taxing for both the instructor and the students. While we hope and expect that students master this material, the...

Courses: Cell Biology Introductory Biology Science Process Skills

primary literatureprokaryotesCell partsEukaryotesOrganelle functionOrganelles

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4195

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724

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Using Yeast to Make Scientists: A Six-Week Student-Driven Research Project for the Cell Biology Laboratory

Traditionally-trained undergraduate students often lack an understanding of science as an active process that yields the information presented in their textbooks. One result has been a call for more research experiences built into traditional...

Courses: Cell Biology Science Process Skills

yeastgrowth curvecell proliferationviability

Lesson

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1014

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Mapping a Mutation to its Gene: The "Fly Lab" as a Modern Research Experience

Although genetics is an invaluable part of the undergraduate biology curriculum, it can be intimidating to students as well as instructors: Students must reduce their reliance on memorization and dive deep into quantitative analysis, and...

Courses: Biochemistry and Molecular Biology Bioinformatics Genetics Science Process Skills

geneticsbioinformaticsdrosophilachi-square analysiscomplementation mappingmode of inheritancethree-point mapping

Lesson

1761

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449

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0

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Why do Some People Inherit a Predisposition to Cancer? A small group activity on cancer genetics

Before undergraduate students take a genetics course they generally know cancer has a genetic basis and involves the proliferation of cells; however, many are uncertain about why only a subset of people have a predisposition to cancer and how that...

Courses: Genetics Science Process Skills

cancerInheritance patternsProbability calculationProto-oncogeneTumor Suppressor Gene

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1553

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454

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Sex-specific differences in Meiosis: Real-world applications

In traditional classrooms, students are typically presented with facts that they are asked to memorize and recall during an exam. The rapid explosion of available scientific facts in recent years has made this model of teaching...

Courses: Cell Biology Genetics Science Process Skills

meiosisReproductionAneuploidyGameteNon-disjunctionOocyteSpermTrisomy

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2517

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473

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Harnessing the Power of the Immune System: Influenza Vaccines

Because most people have been infected by and/or immunized against influenza, students should know how the immune system responds to the infection and how vaccines protect against disease. Vaccines have played an instrumental role in disease...

Courses: Biochemistry and Molecular Biology Immunology Science Process Skills

VaccinesInfluenzaImmunizationVaccine efficacy

Lesson

2595

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674

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Teaching Biodiversity with Museum Specimens in an Inquiry-Based Lab

In response to the growth of biology datasets and broad efforts to digitize data, an increasingly important skill for science students is the management and analysis of large datasets. We designed an inquiry-based lab module to introduce students...

Courses: Ecology Ecology Evolution Introductory Biology Science Process Skills

data analysisnatural historyphylogenyBiodiversitymammalsAllen's RuleBergmann's Ruleecogeographymuseum research

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2365

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Exploring Miracle Fruit: An Undergraduate Laboratory Exercise on Experimental Design

In recent years, undergraduate biology and biochemistry curricula have seen an increase in the use of course-based undergraduate research experiences (CUREs). CUREs maximize potential student gains when students take an active role in experimental...

Courses: Biochemistry and Molecular Biology Science Process Skills

sensory systemspHProtein shapeTaste

Lesson

2755

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574

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Using Synthetic Biology and pClone Red for Authentic Research on Promoter Function: Introductory Biology (identifying new promoters)

Students often memorize the definition of a transcriptional promoter but fail to fully understand the critical role promoters play in gene expression. This laboratory lesson allows students to conduct original research by identifying and...

Courses: Genetics Introductory Biology Science Process Skills

bacteriasynthetic biologygene regulationtranscriptionstudent researchcentral dogmacloningpromoterreporter gene/protein

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2485

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172

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A Laboratory Module That Explores RNA Interference and Codon Optimization Through Fluorescence Microscopy Using Caenorhabditis elegans

Scientific research experiences are beneficial to students allowing them to gain laboratory and problem-solving skills, as well as foundational research skills in a team-based setting. We designed a laboratory module to provide a guided research...

Courses: Bioinformatics Cell Biology Developmental Biology Genetics Science Process Skills

microscopyC. elegansquantitative analysisinquiry-based learninggene expressionRNA interferenceCodon UsageLaboratory Module

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Using Bioinformatics and Molecular Visualization to Develop Student Hypotheses in a Malate Dehydrogenase Oriented CURE

Keep It Shrimple: An Adaptable Student-Driven Research Project for the Introductory Biology Laboratory

Breaking It Down: What Factors Control Microbial Decomposition Rates?

Antibiotic Resistance Genes Detection in Environmental Samples

A Short Laboratory Module to Help Infuse Metacognition during an Introductory Course-based Research Experience

Investigating Gene Expression and Cell Specialization in Axolotl Embryos

Generating Biological Hypotheses in a "Course-based Undergraduate Research Experience"(CURE) Course

Why Meiosis Matters: The case of the fatherless snake

An Introduction to Eukaryotic Genome Analysis in Non-model Species for Undergraduates: A tutorial from the Genome Consortium for Active Teaching

Chilling in the Cold: Using Thermal Acclimation to Demonstrate Phenotypic Plasticity in Animals

Bad Cell Reception? Using a cell part activity to help students appreciate cell biology, with an improved data plan and no loss in coverage

Using Yeast to Make Scientists: A Six-Week Student-Driven Research Project for the Cell Biology Laboratory

Mapping a Mutation to its Gene: The "Fly Lab" as a Modern Research Experience

Why do Some People Inherit a Predisposition to Cancer? A small group activity on cancer genetics

Sex-specific differences in Meiosis: Real-world applications

Harnessing the Power of the Immune System: Influenza Vaccines

Teaching Biodiversity with Museum Specimens in an Inquiry-Based Lab

Exploring Miracle Fruit: An Undergraduate Laboratory Exercise on Experimental Design

Using Synthetic Biology and pClone Red for Authentic Research on Promoter Function: Introductory Biology (identifying new promoters)

A Laboratory Module That Explores RNA Interference and Codon Optimization Through Fluorescence Microscopy Using Caenorhabditis elegans

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