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    Taking the Hassle out of Hasselbalch
    Mention pH in a classroom and you can almost see the inner yawn on the faces of your students. The definition may even roll easily from their lips. However, despite multiple exposures to the relationship of pH and pKa throughout a typical...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology Science Process SkillsScience Process Skills

    pHdrug uptakeHenderson-Hasslbalch equationmedical applicationspKa
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    2281

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    430

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    Exploring Miracle Fruit: An Undergraduate Laboratory Exercise on Experimental Design
    In recent years, undergraduate biology and biochemistry curricula have seen an increase in the use of course-based undergraduate research experiences (CUREs). CUREs maximize potential student gains when students take an active role in experimental...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology Science Process SkillsScience Process Skills

    sensory systemspHProtein shapeTaste
    Lesson
    3197

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    212

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    Bringing Pasteur Back to Life: Studying the Biochemistry of Yeast Fermentation Through Discussion Groups and an At-Home Lab
    This hands-on, student-centered biochemistry lesson introduces beginner biochemistry students to the techniques of effectively reading and discussing primary literature, identifying fundamental biological concepts, and applying that knowledge to...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology MicrobiologyMicrobiology Science Process SkillsScience Process Skills

    primary literatureexperimentationyeastMetabolismFermentationRespirationequilibrium
    Lesson
    869

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    125

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    Outside the Norm: Using Public Ecology Database Information to Teach Biostatistics
    Biology students’ understanding of statistics is incomplete due to poor integration of these two disciplines. In some cases, students fail to learn statistics at the undergraduate level due to poor student interest and cursory teaching of...

    Courses: EcologyEcology Introductory BiologyIntroductory Biology Science Process SkillsScience Process Skills

    biostatisticshypothesis testingexperimental design
    Lesson
    1857

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    207

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    A new approach to course-based research using a hermit crab-hydrozoan symbiosis
    There are few feasible models for marine-focused inquiry laboratory activities, a notable shortcoming for instructors seeking to engage their students in meaningful, course-based research experiences (CUREs). We describe a multi-week CURE that...

    Courses: EcologyEcology EvolutionEvolution Introductory BiologyIntroductory Biology Science Process SkillsScience Process Skills

    behaviorparasitismSymbiosismutualismcommensalism
    Lesson
    1159

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    399

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    Teaching the Biological Relevance of Chemical Kinetics Using Cold-Blooded Animal Biology
    This lesson plan was created to support non-chemistry major students in making connections between chemical kinetics and biological systems. Chemical kinetics is often viewed by students as an abstract topic, and one that is limited only to...

    Courses: Introductory BiologyIntroductory Biology Science Process SkillsScience Process Skills

    kineticsMetabolismEctothermPoikilotherm
    Lesson
    2443

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    180

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    Small Organisms with Big Consequences: Understanding the Microbial World Around Us
    Creating a hands-on lab that conveys important information while simultaneously allowing for student autonomy can be difficult. This is particularly true for the field of microbiology, in which labs often rely on “recipe-style”...

    Courses: Introductory BiologyIntroductory Biology MicrobiologyMicrobiology Science Process SkillsScience Process Skills

    disease transmissionmicrobiologymicrobiomeliterature reviewPeer reviewPathogensHealth and WellnessThe Scientific Method
    Lesson
    3521

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    376

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    Using Open-Source Bioinformatics and Visualization Tools to Explore the Structure and Function of SARS-CoV-2 Spike Protein
    The relationship between protein structure and function is a foundational concept in undergraduate biochemistry. We find this theme is best presented with assignments that encourage exploration and analysis. Here, we share a series of four...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology BioinformaticsBioinformatics Science Process SkillsScience Process Skills

    bioinformaticsmolecular modelingCOVID19protein structure and functionUCSF ChimeraSARS-CoV-2 spike proteinACE2 receptor
    Lesson
    1508

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    166

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    Nanoparticles and Shrimp: An Interdisciplinary Lab Series in Chemistry and Biology for Undergraduate Engineering Students
    The parallels between engineering and science are vast, as both disciplines apply theory and inquiry to solve complex problems. In order to prepare students for interdisciplinary careers in STEM, we have developed a lab project in which...

    Courses: Cell BiologyCell Biology EcologyEcology Science Process SkillsScience Process Skills

    microscopychemistry applications in biologytoxicity
    Lesson
    1621

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    459

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    Out of Your Seat and on Your Feet! An adaptable course-based research project in plant ecology for advanced students
    University capstone projects can offer science students a rich research experience that illustrates the process of doing scientific research, and can also help students better choose future academic and career pathways. While capstone projects are...

    Courses: EcologyEcology Plant BiologyPlant Biology Science Process SkillsScience Process Skills

    statisticsactive learningecologyinterdisciplinaryplantscommunicating sciencegroup workfield workproces of science
    Lesson
    1718

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    153

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    Fly Exercise: A Simple Experiment to Test the Physiological Effects of Exercise on a Model Organism
    Model organisms are commonly used to study and experimentally explore biological processes in ways that are technically or ethically not possible in humans. For this reason, model organisms are an essential component of scientific research and...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology Introductory BiologyIntroductory Biology Science Process SkillsScience Process Skills

    exerciseenzyme kineticsmetabolite concentrationmodel speciesphysical activity
    Lesson
    2282

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    679

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    Using Zebrafish in a Developmental Biology Lab Course to Explore Interactions Between Development and the Environment
    Important learning outcomes for biology students include the ability to develop experiments as well as pull together concepts across their coursework. The field of developmental biology, especially environmental influences on development...

    Courses: Developmental BiologyDevelopmental Biology Science Process SkillsScience Process Skills

    toxicologymorphogenesisorganogenesis
    Lesson
    1848

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    489

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    Using Immunocytochemistry and Fluorescence Microscopy Imaging to Explore the Mechanism of Action of Anti-Cancer Drugs on the Cell Cycle
    Understanding and visualizing the cell cycle and mitosis is an essential concept of cell biology. This multi-week lab module has students investigate the mechanism of action of anti-cancer drugs that disrupt activities associated with mitosis and...

    Courses: Cell BiologyCell Biology Science Process SkillsScience Process Skills

    fluorescence microscopymitosisCell StructureCell ImagingImmunocytochemistryQuantitative microscopySTEM skills
    Lesson
    2016

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    388

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    Dynamic Daphnia: An inquiry-based research experience in ecology that teaches the scientific process to first-year biologists
    This authentic research experience lesson teaches the core concept of systems and the competencies of quantitative reasoning, communication, and the ability to apply science. The research is student driven, the results are unknown, and the...

    Courses: EcologyEcology Introductory BiologyIntroductory Biology Science Process SkillsScience Process Skills

    statisticsecologyscientific methodexperimental designAbiotic and Biotic FactorsDependent and Independent Variables