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    Understanding Gastric Acid Secretion: An Active Learning Approach
    The human digestive system is a diverse network of cells, tissues, and organs that is regulated by systemic (e.g., nervous and endocrine systems) and local factors (e.g., secretions, pH, and the microbiome). Given the volume of content and the...
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    1308

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    177

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    Teaching the Photoelectric Effect Using an Open-Source Interactive Simulation
    The photoelectric effect is one of the fundamental experiments that established the basis of quantum mechanics. Students studying this experiment in modern physics courses struggle to understand what it actually measured and why it is significant....
    Lesson
    1808

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    373

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    Plotting Cranial and Spinal Nerve Pathways in a Human Anatomy Lab
    Hands-on experiences with cadavers, animal dissections, or plastic models are effective at improving student learning and attitudes in human anatomy courses. The hands-on experience allows students to visualize and experiment with anatomical...
    Lesson
    1662

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    391

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    Taking the Hassle out of Hasselbalch
    Mention pH in a classroom and you can almost see the inner yawn on the faces of your students. The definition may even roll easily from their lips. However, despite multiple exposures to the relationship of pH and pKa throughout a typical...
    Lesson
    1473

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    521

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    Building a Model of Tumorigenesis: A small group activity for a cancer biology/cell biology course
    The multistep nature of tumorigenesis is a foundational concept in the context of Cancer Biology. Many students do not appreciate the complex nature of cancer development nor do they understand how scientists are able to unravel the molecular...
    Lesson
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    1198

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    Why Meiosis Matters: The case of the fatherless snake
    A compelling reason to learn something can make all the difference in students’ motivation to learn it.  Motivation, in turn, is one of the key attitudes that drives learning.  This story presents students with a compelling puzzle of a...
    Lesson
    1751

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    223

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    Using a Sequential Interpretation of Data in Envelopes (SIDE) approach to identify a mystery TRP channel
    This lesson sought to engage students in data interpretation and to encourage critical thinking about neurophysiology in the context of temperature sensation. A family of receptors called Transient Receptor Potential (TRP) channels are activated...
    Lesson
    593

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    117

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    Visits to the writing center and office hours provide students structured reflection and low-stakes feedback on scientific writing in an Introductory Biology course
    Effective written communication of scientific concepts is a critical, but difficult skill for undergraduate STEM majors to acquire. Oftentimes, the grades of lab reports are negatively impacted by sentence structure and the failure to adhere to...
    Lesson
    2250

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    301

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    Learning Quantitative Genetics: Investigation of Genetic Control for Cold Stress Response in Plants
    Course-embedded undergraduate research experiences (CUREs) for students have been shown to increase students’ understanding of the process of science, affirm their scientific identity, and improve retention in STEM fields. Despite many CUREs...

    Courses: GeneticsGenetics

    Lesson
    12162

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    1857

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    A virtual laboratory on cell division using a publicly-available image database
    Cell division is a key concept in cell biology. While there are many popular activities to teach students the stages of mitosis, most make use of simple schematics, cartoons, or textbook diagrams. Others engage students in acting out the stages,...
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    1206

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    Teaching the Central Dogma Using a Case Study of Genetic Variation in Cystic Fibrosis
    The central dogma of biology is a foundational concept that is traditionally included in genetics curricula at all academic levels. Despite its ubiquitous presence throughout genetics education, students persistently struggle with both the...

    Courses: GeneticsGenetics

    Lesson
    2663

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    229

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    Role of Crop Genetic Diversity on Pathogen Impact: The Tale of Two Pathogens
    Introductory genetics courses are part of the core curriculum in many different fields, including plant breeding, animal science, biology, microbiology, and natural resource management. Concepts involving genes, inheritance, evolution, and genome...
    Lesson
    4769

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    767

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    Teaching Cancer Biology Through a Lens of Social Justice
    The biology classroom is not separate from the greater context of society; social issues can and should be presented in connection with the content. Here we present an example of antiracist teaching using the molecular/cellular biology of cancer...

    Courses: Cell BiologyCell Biology

    Lesson
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    206

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    Isolation and Functional Analysis of a Pancreatic Enzyme in an Introductory Student Lab
    Structure and function are correlated at all levels of biology. This topic is typically addressed early in an undergraduate class in general or molecular biology before students have gained much skill or knowledge in molecular biology. However, an...
    Lesson
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    Sequences and Properties of Gluten Proteins From Different Grains: A Virtual-Friendly Protein Laboratory
    The COVID-19 pandemic has forced much university instruction into virtual modes. As a result, many laboratory courses have either dropped content altogether or replaced hands-on activities with simulations and “dry” labs. Our goal was...
    Lesson
    904

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    334

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    Quantifying Uncertainty and Distinguishing Data Sets in Introductory Physics
    Physics labs are moving increasingly to open-ended experiments where students develop experimental physics skills, rather than verify textbook physics concepts. This sequence of activities sets the stage for this new kind of lab early in the...
    Lesson
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    2631

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    Cell Signaling Pathways - a Case Study Approach
    Signaling and gene expression are fundamental to cell biology and developmental biology. Although these topics are highly interrelated, they typically appear in separate units in a course. We use a series of short problem-based learning exercises...
    Lesson
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    Osmosis Through the Lens of Sexual Health
    Osmosis contributes to a range of biological phenomena, from functioning of nephrons in animals to stomatal opening and closing in plants; yet, scientifically simple ideas about osmosis are common. These ideas limit learners’ comprehension...
    Lesson
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    Using Raw Sequence Data to Analyze Tumor Suppressor Mutations
    Learning to identify DNA sequence variants from raw sequencing data (electropherograms) is a basic molecular biology skill with applications to basic research and clinical practice. Yet learning to map DNA sequence variants to functional regions...
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    From Dirt to Streptomyces DNA
    The purpose of this semester-long Lesson is to give students an authentic, course-based undergraduate research experience during which they learn basic and advanced microbiological and molecular biology techniques. This project begins with the...

    Courses: MicrobiologyMicrobiology