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    Teaching the Photoelectric Effect Using an Open-Source Interactive Simulation
    The photoelectric effect is one of the fundamental experiments that established the basis of quantum mechanics. Students studying this experiment in modern physics courses struggle to understand what it actually measured and why it is significant....
    Lesson
    2982

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    349

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    Serotonin in the Pocket: Non-covalent interactions and neurotransmitter binding
    This lesson introduces beginning biochemistry students to the concept of a biomolecule binding site, such as a neurotransmitter receptor site or an enzyme active site. A simple organic molecule, the neurotransmitter serotonin, is the focus of the...
    Lesson
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    979

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    A clicker-based case study that untangles student thinking about the processes in the central dogma
    The central dogma of biology is a foundational concept that provides a scaffold to understand how genetic information flows in biological systems. Despite its importance, undergraduate students often poorly understand central dogma processes (DNA...
    Lesson
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    827

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    Breaking Bricks: A Hands-On Model of Enzyme Kinetics and Inhibition
    Enzyme kinetics and the impacts of inhibitors on the enzyme's maximal velocity and ability to bind substrates are important topics in cell biology and biochemistry. However, these topics can be difficult for students to grasp when instructed...
    Lesson
    1752

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    603

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    Student-Driven Design-and-Improve Modules to Explore the Effect of Plant Bioactive Compounds in Three Model Organisms
    Engaging and supporting introductory level students in authentic research experiences during required coursework is challenging. Plant bioactive compounds attract students' natural curiosity as they are found in many familiar items such as...
    Lesson
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    374

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    The ACTN3 Polymorphism: Applications in Genetics and Physiology Teaching Laboratories
    Inquiry-based undergraduate laboratories provide the opportunity to engage students in a research experience that improves scientific thinking, but such activities can be difficult to develop and implement due to limited time and resources. We...
    Lesson
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    459

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    Exploring Miracle Fruit: An Undergraduate Laboratory Exercise on Experimental Design
    In recent years, undergraduate biology and biochemistry curricula have seen an increase in the use of course-based undergraduate research experiences (CUREs). CUREs maximize potential student gains when students take an active role in experimental...
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    617

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    Predicting and classifying effects of insertion and deletion mutations on protein coding regions
    Mutations in genes can affect the encoded proteins in multiple ways, and some of these effects are counterintuitive. As for any other knowledge, students must create their own deep understanding of the Central Dogma. Students may not develop this...
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    4333

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    83

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    The Great Petunia Carnage of 2017: A Clicker Case Study Using Petunias to Describe the Effect of Genetic Modification on the Biochemistry of Flower Color and Phenotype in Plants
    In this single class period case study, students examine the difference between genotype and phenotype by studying the mechanisms by which commercially available petunias have been bred to have different phenotypes (flower colors). Students review...
    Lesson
    2053

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    586

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    BioVEDA Curriculum: An Approach to Link Conceptual and Quantitative Understanding of Variation During Experimental Design and Data Analysis
    When performing a biological investigation, experts constantly cycle between conceptual and quantitative modes of thinking, integrating their understanding in both worlds to make decisions about their work. This cycling and mixing of conceptual...
    Lesson
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    448

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    Teaching Advanced Concepts in Regulation of the Lac Operon With Modeling and Simulation
    Success in biochemistry and other life science courses requires that students understand important biological concepts. One of these concepts is how gene regulation ensures that homeostasis is maintained in an organism. The lac operon is a...
    Lesson
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    496

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    Necessary and Sufficient? Solving the Mystery of the Mitochondrial Pyruvate Transporter
    While there are several available lessons for teaching introductory biology students about diffusion, facilitated diffusion, and active transport, fewer materials exist to support upper-division students' understanding of the proteins that...

    Courses: Cell BiologyCell Biology

    Lesson
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    853

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    Furry with a chance of evolution: Exploring genetic drift with tuco-tucos
    Genetic drift is an important mechanism of evolution, yet undergraduates often fail to understand how it leads to evolutionary change due in part to its random nature. This lesson plan describes a simulation-based activity that allows students to...

    Courses: EvolutionEvolution

    Lesson
    1651

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    244

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    Make It Stick: Teaching Gene Targeting with Ribbons and Fasteners
    Manipulating gene expression is a commonly used tool to study the effect of a single gene or the hierarchy of gene networks in many different biological disciplines. When working with mice, the most commonly used techniques to manipulate genes...
    Lesson
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    405

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    Teaching the Biological Relevance of Chemical Kinetics Using Cold-Blooded Animal Biology
    This lesson plan was created to support non-chemistry major students in making connections between chemical kinetics and biological systems. Chemical kinetics is often viewed by students as an abstract topic, and one that is limited only to...
    Lesson
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    467

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    Ain't No Mountain Pine Enough: A Case Study of How Mountain Pine Beetles are Affecting Ecosystem Processes
    This case study engages students in generating hypotheses and predictions, analyzing and interpreting data, critically evaluating contrasting results in science, and thinking about feedbacks between biota and abiotic ecosystem dynamics. To address...

    Courses: EcologyEcology

    Lesson
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    576

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    Linking Genotype to Phenotype: The Effect of a Mutation in Gibberellic Acid Production on Plant Germination
    Basic concepts in genetics and plant development are often taught in lecture courses without a lab component. This approach provides students with the content knowledge, but fails to make connections to research opportunities and real-world...
    Lesson
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    528

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    Using Immunocytochemistry and Fluorescence Microscopy Imaging to Explore the Mechanism of Action of Anti-Cancer Drugs on the Cell Cycle
    Understanding and visualizing the cell cycle and mitosis is an essential concept of cell biology. This multi-week lab module has students investigate the mechanism of action of anti-cancer drugs that disrupt activities associated with mitosis and...
    Lesson
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    394

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    Taking the Hassle out of Hasselbalch
    Mention pH in a classroom and you can almost see the inner yawn on the faces of your students. The definition may even roll easily from their lips. However, despite multiple exposures to the relationship of pH and pKa throughout a typical...
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    Nanoparticles and Shrimp: An Interdisciplinary Lab Series in Chemistry and Biology for Undergraduate Engineering Students
    The parallels between engineering and science are vast, as both disciplines apply theory and inquiry to solve complex problems. In order to prepare students for interdisciplinary careers in STEM, we have developed a lab project in which...