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    Workshop Report: Summer 2020 Virtual CRISPR in the Classroom
    As innovations and developments in genome editing technologies using CRISPR-Cas systems progress, the need to disseminate relevant knowledge and build skills among the next generation of young scientists in undergraduate classrooms is vital. Our...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology BioinformaticsBioinformatics GeneticsGenetics Professional Development and Career PlanningProfessional Development and Career Planning

    geneticscrisprGenome Analysisgene editingbacterial immunity
    Lesson
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    362

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    Bacteria to Brains in Backyard Coyotes: An Interdisciplinary Pedagogical Case Study
    Our interdisciplinary pedagogical case study explores the differences between rural and urban coyotes at the levels of organismal and community ecology. The focus is on how coyotes’ gut microbiomes could affect their behavior via...

    Courses: Cell BiologyCell Biology EcologyEcology EvolutionEvolution ImmunologyImmunology Introductory BiologyIntroductory Biology MicrobiologyMicrobiology

    dietanimal behaviorimmune systemmicrobiomeNervous systemgut-brain axisImmunoReachdysbiosisCoyoteCytokines
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    641

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    Follow the Sulfur: Using Yeast Mutants to Study a Metabolic Pathway
    Students are frequently overwhelmed by the complexity of metabolic pathways and they think they have "learned" the pathway when they have memorized the individual reactions.  This laboratory lesson helps students to understand the...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology GeneticsGenetics Introductory BiologyIntroductory Biology MicrobiologyMicrobiology Science Process SkillsScience Process Skills

    SelectionyeastMetabolismcysteinemediamethioninemutantPathwaysulfur
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    2285

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    278

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    Discovering Prokaryotic Gene Regulation by Building and Investigating a Computational Model of the lac Operon
    The ability to construct and reason through a biological system is an important skill to develop in science education. This level of understanding forces students to recognize the interrelatedness of components within a biological process and...

    Courses: Introductory BiologyIntroductory Biology

    prokaryotesgene regulationLac Operoninducible operon
    Lesson
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    453

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    Moths and Frogs and E. coli, Oh My!: Agent-based Modeling of Evolutionary Systems
    In evolution classrooms, introducing and reinforcing the idea of genetic drift and random selection can be challenging, as can be reinforcing appropriate mental models of evolution. Agent-based models offer students the opportunity to conduct a...

    Courses: BioinformaticsBioinformatics EcologyEcology EvolutionEvolution Science Process SkillsScience Process Skills

    modelingEvolutionecologyagent-based modelingGenetic Driftenvironmental scienceNatural Selectioncompetitive coevolutionsimulation modelingevolutionary reasoning
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    210

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    Modeling Strep Throat Detection, Infection, and Spread Using an SIR Model and the Vensim Simulation Software
    The overarching goal of this lesson is to provide students with an opportunity to gain experience making and using biological models. Biological modeling can be used to investigate complex, real-world problems so that predictions can be made about...

    Courses: Cell BiologyCell Biology ImmunologyImmunology Introductory BiologyIntroductory Biology MicrobiologyMicrobiology

    infectious diseasebiological modelingSIR model
    Lesson
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    496

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    Harnessing the Power of the Immune System: Influenza Vaccines
    Because most people have been infected by and/or immunized against influenza, students should know how the immune system responds to the infection and how vaccines protect against disease. Vaccines have played an instrumental role in disease...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology ImmunologyImmunology Science Process SkillsScience Process Skills

    VaccinesInfluenzaImmunizationVaccine efficacy
    Essay
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    121

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    An Active Textbook Converts "Vision and Tweak" to Vision and Change
    Multiple reports over more than a century have documented the problems with the way introductory biology has been taught in most colleges and universities. An influential recent report, Vision and Change in Undergraduate Biology Education, has...

    Courses: Introductory BiologyIntroductory Biology

    Vision and Changeactive learningintroductory biologyFlipped classroomUndergraduatecore competenciescore conceptsactive textbookcurriculum reform
    Teaching Tools and Strategies
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    1718

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    A 360˚ View of COVID-19
    In March 2020, institutions underwent a massive transition to distance learning as a result of the COVID-19 pandemic. With so little time to devise new materials to maximize learning in the new virtual environment, instructors devised a variety of...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology BioinformaticsBioinformatics Cell BiologyCell Biology EvolutionEvolution GeneticsGenetics ImmunologyImmunology Introductory BiologyIntroductory Biology MicrobiologyMicrobiology Science Process SkillsScience Process Skills

    geneticsImmunologyBiochemistrybioinformaticsmolecular evolutionpublic healthvirusCOVID19
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    103

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    Exploring Indigenous Viewpoints in the Undergraduate Biology Classroom: An Environmental Case Study Incorporating Hawaiian Traditional Ecological Knowledge
    Changing science education to foster greater equity and inclusion for Indigenous students will require effort from instructors and institutions. Instructors can help by including Traditional Ecological Knowledge (TEK) in their science classrooms....

    Courses: EcologyEcology Introductory BiologyIntroductory Biology Science Process SkillsScience Process Skills

    ecologycase studyenvironmentsystems thinkingTraditional ecological knowledgeindigenous knowledgehawai'idecolonizing scienceNative knowledgeFish ponds
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    518

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    A Remote Introductory Biology Lab Using Backyard Birdwatching to Teach Data Analysis and Communication
    Asking questions, designing experiments, collecting data and interpreting those data, and communicating the results are some of the most important concepts an undergraduate biology lab can teach students. When the SARS-CoV2 pandemic forced our...

    Courses: EcologyEcology Introductory BiologyIntroductory Biology Science Process SkillsScience Process Skills

    ecologydata analysisdata collection
    Essay
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    202

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    Thinking deeply about quantitative analysis: Building a Biologist's Toolkit
    Vision and Change in Undergraduate Biology Education encouraged faculty to focus on core concepts and competencies in undergraduate curriculum. We created a sophomore-level course, Biologists' Toolkit, to focus on the competencies of...

    Courses: Introductory BiologyIntroductory Biology

    Vision and ChangeRRStudioquantitative literacystatistical analysisScientific communication
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    320

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    Marsh Madness: Using Video Games and a Case Study to Explore Food Webs and Ecosystem Services in Carpinteria Salt Marsh Reserve
    As the complexity and interconnectedness of our world increases, we are continually expected to be capable of complex, non-linear thinking in order to successfully tackle and solve the challenges we face in the 21st century. Tackling these...

    Courses: EcologyEcology

    food webssystems thinkingGame Based LearningEcosystem Servicessocio-ecological networks
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    285

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    Garden Variety Mutations: Using Primary Data to Understand the Central Dogma in Large-Lecture Introductory Biology
    The ability to interpret and create an argument from data is a crucial skill for budding scientists, yet one that is seldom practiced in introductory courses. During this argumentation module, students in a large lecture class will work in groups...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology GeneticsGenetics Introductory BiologyIntroductory Biology

    mutationtranscriptiongene expressioncentral dogmatranslationgel electrophoresisGenotype/Phenotype
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    517

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    A Simple Method for Predicting a Molecule's Biological Properties From Its Polarity
    The distinction between very polar and less polar substances is a foundation of biochemistry, cell biology, and physiology; it surfaces in multiple concept inventories and elaborations of biological core concepts. However, in our experience, most...

    Courses: Anatomy-PhysiologyAnatomy-Physiology Biochemistry and Molecular BiologyBiochemistry and Molecular Biology Cell BiologyCell Biology Introductory BiologyIntroductory Biology

    Diffusionsolubilitycovalent bondshydrophilichydrophobicpartition coefficientplasma membranepolarity
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    369

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    Online Adaptation of the Cell Engineer/Detective Lesson
    One of the most fundamental themes of biology is the relationship between structure and function, which is particularly evident when it comes to cells; however, the traditional cartoon depictions of cells that are often used to help teach the...

    Courses: Cell BiologyCell Biology Introductory BiologyIntroductory Biology Science Process SkillsScience Process Skills

    cell functionCell StructureOrganelles
    Lesson
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    184

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    Nanoparticles and Shrimp: An Interdisciplinary Lab Series in Chemistry and Biology for Undergraduate Engineering Students
    The parallels between engineering and science are vast, as both disciplines apply theory and inquiry to solve complex problems. In order to prepare students for interdisciplinary careers in STEM, we have developed a lab project in which...

    Courses: Cell BiologyCell Biology EcologyEcology Science Process SkillsScience Process Skills

    microscopychemistry applications in biologytoxicity
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    475

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    A Lesson on Matter and Energy at the Organismal Scale: Linking Patterns and Processes Across Diverse Taxa
    Pathways and transformations of energy and matter (PTEM) are a conceptually challenging but essential component of biological literacy. Curricular gaps about PTEM nevertheless remain; although lessons targeting PTEM at small scales (chemical,...

    Courses: EcologyEcology Introductory BiologyIntroductory Biology

    plantsenergyAnimalsfungimatterorganismal scale
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    3025

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    550

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    An Original-Design Board Game to Increase Student Comprehension of Cellular Respiration Pathways
    Cellular respiration is a daunting topic for many students in introductory biology courses. Students are challenged at conceptual and factual levels, since instruction covers multiple metabolic pathways occurring across different cellular...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology Cell BiologyCell Biology Introductory BiologyIntroductory Biology Science Process SkillsScience Process Skills

    GlycolysisCellular RespirationFermentationKrebs CycleOxidative phosphorylationpyruvate oxidation
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    The Great Petunia Carnage of 2017: A Clicker Case Study Using Petunias to Describe the Effect of Genetic Modification on the Biochemistry of Flower Color and Phenotype in Plants
    In this single class period case study, students examine the difference between genotype and phenotype by studying the mechanisms by which commercially available petunias have been bred to have different phenotypes (flower colors). Students review...

    Courses: GeneticsGenetics Introductory BiologyIntroductory Biology Plant BiologyPlant Biology

    case studyGenetic ModificationsBiochemistry of Flower ColorGMO regulationsGenotype-Phenotype Connections