CourseSource: Resources

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1620

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544

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Investigating the Function of a Transport Protein: Where is ABCB6 Located in Human Cells?

One of the challenges of teaching Cell Biology is helping students understand important research methods used to study cells. The goal of understanding cell biology methods is especially challenging in courses without a laboratory...

Courses: Cell Biology

ABC transporter familyDifferential centrifugationImmunoblottingImmunofluorescence assayProtein localizationPurifying organellesSDS-PAGE

Lesson

2141

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496

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0

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Necessary and Sufficient? Solving the Mystery of the Mitochondrial Pyruvate Transporter

While there are several available lessons for teaching introductory biology students about diffusion, facilitated diffusion, and active transport, fewer materials exist to support upper-division students' understanding of the proteins that...

Courses: Cell Biology

DiffusionActive transportfacilitated diffusionNecessary and sufficientTransport proteins

Lesson

1903

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474

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0

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Why do Some People Inherit a Predisposition to Cancer? A small group activity on cancer genetics

Before undergraduate students take a genetics course they generally know cancer has a genetic basis and involves the proliferation of cells; however, many are uncertain about why only a subset of people have a predisposition to cancer and how that...

Courses: Genetics Science Process Skills

cancerInheritance patternsProbability calculationProto-oncogeneTumor Suppressor Gene

Lesson

3265

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547

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0

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A Student-Led Hearing on the Use of HeLa Cells in Research

In this role-playing case study, students will learn about the HeLa cell line and its origins while examining multiple perspectives surrounding the cell line and its uses. The goal of this case study is for students to use guided questions to...

Courses: Cell Biology Science Process Skills

bioethicsscience policycell culturedebateHeLa cellsinformed consentrole playsocial justice issues

Lesson

540

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81

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0

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Using Raw Sequence Data to Analyze Tumor Suppressor Mutations

Learning to identify DNA sequence variants from raw sequencing data (electropherograms) is a basic molecular biology skill with applications to basic research and clinical practice. Yet learning to map DNA sequence variants to functional regions...

Courses: Bioinformatics Genetics

bioinformaticsmutationDNAgenomic visualizationparts of a geneclinical consequencesraw data

Lesson

3135

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367

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0

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Developing Decolonial Consciousness in Biology Students Through Critical Reflection Assignments

There is a growing call to decolonize curricula in academia, including in scientific disciplines. In the biology classroom, this includes highlighting a diverse array of scientists and illuminating injustice and exploitation carried out by...

Courses: Ecology Ecology Evolution Science Process Skills

primatessocietyZoologyantiracismdecolonizingstudent activismmuseum science

Lesson

1236

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167

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0

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Mock Drug Activity Enhances Student Learning About the Challenges of HIV/AIDS Therapy

While traditional didactic coursework is important for learning about the scientific aspects of HIV/AIDS, it is difficult to convey social aspects of the epidemic. Due to effective drug therapies, an HIV diagnosis is now considered a chronic...

Courses: Microbiology

drug resistanceRetrovirusViral replication

Lesson

1849

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310

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Science and Society: Integrating Historical Science Materials Into an Undergraduate Biology Course

Vision and Change in Undergraduate Biology Education (American Association for the Advancement of Science, 2011) stresses the importance of fostering an understanding of the relationship between science and society. We describe a library-based...

Courses: Microbiology

infectious diseasevaccinationbacteriavirusesantibiotics

Lesson

332

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53

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0

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Using an Interactive Game, Gutsy, to Examine the Impacts of Pathogens and Everyday Events on the Human Gut Microbiome

The human gut microbiome is often associated with ‘good bacteria’ in marketing campaigns for dietary supplements, probiotic drinks, and fermented foods. Yet, the dynamic and complex community of microbes that make up the gut microbiome...

Courses: Anatomy-Physiology Immunology Microbiology

bacteriaGamepathogenhealthmicrobiomediversity

Essay

1391

views

233

downloads

2

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Designing an Asynchronous, Self-Led Aquatic Ecology Field Trip

Due to the COVID-19 pandemic and increasing need to teach students online, aquatic scientists are looking for ways to give students field experiences virtually. Asynchronous, self-led field trips are emerging as a solution. However, due to the...

Courses: Ecology Ecology

observationecosystem structureexploration

Essay

826

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125

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0

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Implementing active learning approaches into an upper-division biology course

In this essay, we present our strategy for implementing active learning strategies into an upper division course on Human Genetics. Our principal goal was to shift from a traditional didactic course design, to one that more clearly placed the...

Courses: Genetics Introductory Biology

human biologyPedigree analysisRare genetic diseases

Essay

1218

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178

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0

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Squirreling from Afar: Adapting Squirrel-Net Modules for Remote Teaching and Learning

The shift from face-to-face instruction to remote teaching and learning has proven to be a challenging endeavor for many reasons, including lack of time, resources, and inspiration. Lab courses, the "hands-on" portion of many curricula,...

Courses: Ecology Ecology Introductory Biology Science Process Skills

online learningbehavioral ecologyCUREsRemote teachingfield ecologySquirrelSquirrel-Net

Teaching Tools and Strategies

1865

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383

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0

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Converting a Face-to-Face Lab to Online: An Example of Process and Outcomes for a CRISPR-Based Molecular Biology Lab

The COVID-19 pandemic created a need to convert in-person laboratory courses into an online format in a short amount of time. For this reason, we converted our face-to-face molecular biology lab course to an online version in Spring 2020. The lab...

Courses: Genetics Science Process Skills

mutationtranscriptioncrisprtranslation

Lesson

2041

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229

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0

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A new approach to course-based research using a hermit crab-hydrozoan symbiosis

There are few feasible models for marine-focused inquiry laboratory activities, a notable shortcoming for instructors seeking to engage their students in meaningful, course-based research experiences (CUREs). We describe a multi-week CURE that...

Courses: Ecology Ecology Evolution Introductory Biology Science Process Skills

behaviorparasitismSymbiosismutualismcommensalism

Science Behind the Lesson

654

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58

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X-ploring Fragile X: The Science Behind the Syndrome

Fragile X Syndrome is an X-linked genetic disorder resulting from the impairment of transcription of the FMR1 gene, producing less to no FMRP protein. FMRP is a translational inhibitor that plays a key role in neurological development. Recent...

Courses: Biochemistry and Molecular Biology Genetics Introductory Biology

epigeneticsgene regulationtranscriptioncentral dogmatranslationFragile X syndromeSphingosine Metabolism

Teaching Tools and Strategies

1287

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299

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Sanger Sequencing by Hand: Using Paper Clips to Demonstrate Chain Termination

Sanger sequencing is commonly taught with a hands-on approach. Sanger sequencing involves chain termination by dideoxynucleotides, because they are missing the oxygen on the 3’ carbon atom, which is required for the addition of subsequent...

Courses: Genetics

nucleotidessequencingDNAgel electrophoresisChain Termination

Teaching Tools and Strategies

4485

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468

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"I Really Enjoy These Annotations:" Examining Primary Biological Literature Using Collaborative Annotation

Critically reading and evaluating claims made in the primary literature are vital skills for the future professional and personal lives of undergraduate students. However, the formal presentation of intricate content in primary research articles...

Courses: Developmental Biology Neurobiology

Stem cellsAdult neurogenesisCRISPR gene editing

Teaching Tools and Strategies

863

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133

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A Team-Based Approach to Course Development Involving Undergraduate Researchers

Development of an undergraduate laboratory course can be a challenge, because of the need to balance both logistical and pedagogical considerations. We piloted a team-based approach to developing this type of course and found it to be advantageous...

Courses: Biochemistry and Molecular Biology Bioinformatics Genetics Microbiology Science Process Skills

student researchcourse development

Teaching Tools and Strategies

750

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66

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0

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A Journal Club Project to Promote Interpreting and Presenting Information From the Primary Scientific Literature

Many undergraduate students receive little guidance on how to critically read, interpret data within, or present information from the primary scientific literature before they begin senior independent research experiences or enter professional or...

Courses: Developmental Biology Neurobiology

primary literaturejournal clubScience CommunicationfeedbackPeer reviewgroup workOral presentationProcess skillsPeer evaluationDevelopmental neurobiology

Lesson

3757

views

284

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0

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Fragile States: A Case Study Exploring Genetics, Molecular Biology, and Biochemistry Through the Lens of Fragile X Syndrome

This case aims to strengthen students’ understanding of molecular biology concepts through study of Fragile X Syndrome (FXS). Students begin by learning the cause and phenotypes of FXS and related conditions. Students then apply genetics...

Courses: Biochemistry and Molecular Biology Genetics

gene regulationtranscriptiontranslationFragile X syndrometriplet repeat expansionsex linkagemetabolic pathway

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Investigating the Function of a Transport Protein: Where is ABCB6 Located in Human Cells?

Necessary and Sufficient? Solving the Mystery of the Mitochondrial Pyruvate Transporter

Why do Some People Inherit a Predisposition to Cancer? A small group activity on cancer genetics

A Student-Led Hearing on the Use of HeLa Cells in Research

Using Raw Sequence Data to Analyze Tumor Suppressor Mutations

Developing Decolonial Consciousness in Biology Students Through Critical Reflection Assignments

Mock Drug Activity Enhances Student Learning About the Challenges of HIV/AIDS Therapy

Science and Society: Integrating Historical Science Materials Into an Undergraduate Biology Course

Using an Interactive Game, Gutsy, to Examine the Impacts of Pathogens and Everyday Events on the Human Gut Microbiome

Designing an Asynchronous, Self-Led Aquatic Ecology Field Trip

Implementing active learning approaches into an upper-division biology course

Squirreling from Afar: Adapting Squirrel-Net Modules for Remote Teaching and Learning

Converting a Face-to-Face Lab to Online: An Example of Process and Outcomes for a CRISPR-Based Molecular Biology Lab

A new approach to course-based research using a hermit crab-hydrozoan symbiosis

X-ploring Fragile X: The Science Behind the Syndrome

Sanger Sequencing by Hand: Using Paper Clips to Demonstrate Chain Termination

"I Really Enjoy These Annotations:" Examining Primary Biological Literature Using Collaborative Annotation

A Team-Based Approach to Course Development Involving Undergraduate Researchers

A Journal Club Project to Promote Interpreting and Presenting Information From the Primary Scientific Literature

Fragile States: A Case Study Exploring Genetics, Molecular Biology, and Biochemistry Through the Lens of Fragile X Syndrome

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