CourseSource: Resources

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A Laboratory Module That Explores RNA Interference and Codon Optimization Through Fluorescence Microscopy Using Caenorhabditis elegans

Scientific research experiences are beneficial to students allowing them to gain laboratory and problem-solving skills, as well as foundational research skills in a team-based setting. We designed a laboratory module to provide a guided research...

Courses: Bioinformatics Cell Biology Developmental Biology Genetics Science Process Skills

microscopyC. elegansquantitative analysisinquiry-based learninggene expressionRNA interferenceCodon UsageLaboratory Module

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904

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54

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A Structured Inquiry-Based Module for the Undergraduate Cell Biology Laboratory That Teaches Fundamental Concepts of Cell Differentiation

Pedagogical research in science education has shown that students effectively learn science by doing science. As a result, there is increased interest in bringing research-like experiences into the classroom, particularly for laboratory courses....

Courses: Cell Biology

fluorescence microscopygene expressionpolymerase chain reactionCell Structurecell culturewestern blottingdifferentiationreverse transcription

Lesson

4536

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763

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Using Yeast to Make Scientists: A Six-Week Student-Driven Research Project for the Cell Biology Laboratory

Traditionally-trained undergraduate students often lack an understanding of science as an active process that yields the information presented in their textbooks. One result has been a call for more research experiences built into traditional...

Courses: Cell Biology Science Process Skills

yeastgrowth curvecell proliferationviability

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1653

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299

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A Hybrid Virtual Kinesiology Laboratory Module for Human Anatomy and Physiology

The integration of virtual technology is becoming a common trend in anatomy education at the undergraduate and graduate levels. The incorporation of virtual 3D anatomical models into the classroom is beneficial to students, especially if they do...

Courses: Anatomy-Physiology

kinesiologyexercise physiologyAnaerobic RespirationMaximum Oxygen ConsumptionMuscular SystemVirtual AnatomyWingate Test

Teaching Tools and Strategies

863

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133

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A Team-Based Approach to Course Development Involving Undergraduate Researchers

Development of an undergraduate laboratory course can be a challenge, because of the need to balance both logistical and pedagogical considerations. We piloted a team-based approach to developing this type of course and found it to be advantageous...

Courses: Biochemistry and Molecular Biology Bioinformatics Genetics Microbiology Science Process Skills

student researchcourse development

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6119

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1234

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A CURE for Salmonella: A Laboratory Course in Pathogen Microbiology and Genomics

Rapid advances in genomics and bioinformatics, the vast amount of data generated by next-generation sequencing, and the penetration of the ‘-omics’ into many areas of biology have created a need for students with hands-on experience with...

Courses: Biochemistry and Molecular Biology Bioinformatics Ecology Ecology Microbiology

epidemiologyresearchbioinformaticsgenomicspublic healthAntibiotic Resistant BacteriaSalmonellaDNA sequencingpathogenic bacteria

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5031

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909

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Tackling "Big Data" with Biology Undergrads: A Simple RNA-seq Data Analysis Tutorial Using Galaxy

Analyzing high-throughput DNA sequence data is a fundamental skill in modern biology. However, real and perceived barriers such as massive file sizes, substantial computational requirements, and lack of instructor background knowledge can...

Courses: Biochemistry and Molecular Biology Bioinformatics

bioinformaticsDNA sequenceRNAseqgene expression

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3356

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1180

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CRISPR/Cas9 in yeast: a multi-week laboratory exercise for undergraduate students

Providing undergraduate life-science students with a course-based research experience that utilizes cutting-edge technology, is tractable for students, and is manageable as an instructor is a challenge. Here, I describe a multi-week lesson plan...

Courses: Biochemistry and Molecular Biology Bioinformatics Genetics Microbiology Science Process Skills

bioinformaticsPCRphenotypingCRISPR/Cas9gene editingcloningGenotypingRestriction enzyme

Essay

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268

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An Introduction to the Squirrel-Net Teaching Modules

Although course-based undergraduate research experiences (CUREs) are gaining popularity in biology, most are designed for benchwork-based laboratory courses while few focus on field-based skills. Many barriers to implementing field CUREs exist,...

Courses: Ecology Ecology

ecologybehaviortrade-offsScientific ProcessSquirrel-Net

Lesson

1063

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168

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Outside the Norm: Using Public Ecology Database Information to Teach Biostatistics

Biology students’ understanding of statistics is incomplete due to poor integration of these two disciplines. In some cases, students fail to learn statistics at the undergraduate level due to poor student interest and cursory teaching of...

Courses: Ecology Ecology Introductory Biology Science Process Skills

biostatisticshypothesis testingexperimental design

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373

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The ACTN3 Polymorphism: Applications in Genetics and Physiology Teaching Laboratories

Inquiry-based undergraduate laboratories provide the opportunity to engage students in a research experience that improves scientific thinking, but such activities can be difficult to develop and implement due to limited time and resources. We...

Courses: Anatomy-Physiology Genetics

protein structure and functionhuman genetic variationmuscle physiology

Lesson

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916

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Assessing Urban Biodiversity With the eBird Citizen Science Project: A Course-Based Undergraduate Research Experience (CURE) Module

The eBird citizen science module takes advantage of technology tools and online resources developed by the Cornell Laboratory of Ornithology (http://ebird.org) to achieve several learning objectives embedded in a semester-long upper-level biology...

Courses: Ecology Ecology Science Process Skills

datacitizen sciencecommunityBiodiversitySpecieshypothesishabitat

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2560

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641

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Follow the Sulfur: Using Yeast Mutants to Study a Metabolic Pathway

Students are frequently overwhelmed by the complexity of metabolic pathways and they think they have "learned" the pathway when they have memorized the individual reactions. This laboratory lesson helps students to understand the...

Courses: Biochemistry and Molecular Biology Genetics Introductory Biology Microbiology Science Process Skills

SelectionyeastMetabolismcysteinemediamethioninemutantPathwaysulfur

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890

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Exploration of the Human Genome by Investigation of Personalized SNPs

Students often shy away from tedious bioinformatics approaches to exploring their genomes. However, in our expanding digital world these skills are some of the most relevant and valuable. To increase students' interest in their own genomes, I...

Courses: Bioinformatics Genetics Science Process Skills

UCSC genome browsersingle nucleotide polymorphismGenome wide association studiesGenomic organization

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172

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To Vaccinate or Not to Vaccinate

To vaccinate or not to vaccinate, that is the question. Much of the recent trend in society against vaccination is that the general population does not understand 1) how vaccines work and 2) how one's vaccination status can influence others....

Courses: Anatomy-Physiology Biochemistry and Molecular Biology Introductory Biology Microbiology

pathogenELISAimmunityantibodyAntigen

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Data, Distributions, and Hypotheses: Exploring Diversity and Disturbance in the Tallgrass Prairie

Proper hypothesis generation, data handling, graphing, and communication are essential skills that undergraduate majors in biology are expected to master. However, students rarely get hands-on practice that helps them to effectively develop these...

Courses: Ecology Ecology Plant Biology

Quantitative reasoningRestoration EcologyScience process skillstall grass prairie ecosystem

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Design Your Own Flow Cytometry Experiment: A Four-Week Inquiry Laboratory

Due to its importance to the field, flow cytometry should be one of the hallmark methods a student learns in the lab portion of an undergraduate immunology course. Flow cytometry is a classic lab technique utilized within immunology and molecular...

Courses: Immunology

Immunologyexperimental designFlow cytometryMice

Lesson

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229

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A new approach to course-based research using a hermit crab-hydrozoan symbiosis

There are few feasible models for marine-focused inquiry laboratory activities, a notable shortcoming for instructors seeking to engage their students in meaningful, course-based research experiences (CUREs). We describe a multi-week CURE that...

Courses: Ecology Ecology Evolution Introductory Biology Science Process Skills

behaviorparasitismSymbiosismutualismcommensalism

Lesson

3072

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453

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Moths and Frogs and E. coli, Oh My!: Agent-based Modeling of Evolutionary Systems

In evolution classrooms, introducing and reinforcing the idea of genetic drift and random selection can be challenging, as can be reinforcing appropriate mental models of evolution. Agent-based models offer students the opportunity to conduct a...

Courses: Bioinformatics Ecology Ecology Evolution Science Process Skills

modelingEvolutionecologyagent-based modelingGenetic Driftenvironmental scienceNatural Selectioncompetitive coevolutionsimulation modelingevolutionary reasoning

Review

1582

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237

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Workshop Report: Summer 2020 Virtual CRISPR in the Classroom

As innovations and developments in genome editing technologies using CRISPR-Cas systems progress, the need to disseminate relevant knowledge and build skills among the next generation of young scientists in undergraduate classrooms is vital. Our...

Courses: Biochemistry and Molecular Biology Bioinformatics Genetics Professional Development and Career Planning

geneticscrisprGenome Analysisgene editingbacterial immunity

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A Laboratory Module That Explores RNA Interference and Codon Optimization Through Fluorescence Microscopy Using Caenorhabditis elegans

A Structured Inquiry-Based Module for the Undergraduate Cell Biology Laboratory That Teaches Fundamental Concepts of Cell Differentiation

Using Yeast to Make Scientists: A Six-Week Student-Driven Research Project for the Cell Biology Laboratory

A Hybrid Virtual Kinesiology Laboratory Module for Human Anatomy and Physiology

A Team-Based Approach to Course Development Involving Undergraduate Researchers

A CURE for Salmonella: A Laboratory Course in Pathogen Microbiology and Genomics

Tackling "Big Data" with Biology Undergrads: A Simple RNA-seq Data Analysis Tutorial Using Galaxy

CRISPR/Cas9 in yeast: a multi-week laboratory exercise for undergraduate students

An Introduction to the Squirrel-Net Teaching Modules

Outside the Norm: Using Public Ecology Database Information to Teach Biostatistics

The ACTN3 Polymorphism: Applications in Genetics and Physiology Teaching Laboratories

Assessing Urban Biodiversity With the eBird Citizen Science Project: A Course-Based Undergraduate Research Experience (CURE) Module

Follow the Sulfur: Using Yeast Mutants to Study a Metabolic Pathway

Exploration of the Human Genome by Investigation of Personalized SNPs

To Vaccinate or Not to Vaccinate

Data, Distributions, and Hypotheses: Exploring Diversity and Disturbance in the Tallgrass Prairie

Design Your Own Flow Cytometry Experiment: A Four-Week Inquiry Laboratory

A new approach to course-based research using a hermit crab-hydrozoan symbiosis

Moths and Frogs and E. coli, Oh My!: Agent-based Modeling of Evolutionary Systems

Workshop Report: Summer 2020 Virtual CRISPR in the Classroom

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