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    The Leaky Neuron: Understanding synaptic integration using an analogy involving leaky cups
    Students have difficulty understanding synaptic integration in neural circuits, and how spatial and temporal summation combine in a target neuron to reach threshold.  This Lesson uses small cups of water to represent excitatory postsynaptic...

    Courses: NeurobiologyNeurobiology

    Lesson
    1761

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    226

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    Using a Sequential Interpretation of Data in Envelopes (SIDE) approach to identify a mystery TRP channel
    This lesson sought to engage students in data interpretation and to encourage critical thinking about neurophysiology in the context of temperature sensation. A family of receptors called Transient Receptor Potential (TRP) channels are activated...
    Lesson
    1653

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    299

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    A Hybrid Virtual Kinesiology Laboratory Module for Human Anatomy and Physiology
    The integration of virtual technology is becoming a common trend in anatomy education at the undergraduate and graduate levels. The incorporation of virtual 3D anatomical models into the classroom is beneficial to students, especially if they do...
    Lesson
    1991

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    376

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    Engaging Undergraduates in Mechanisms of Tubular Reabsorption and Secretion in the Mammalian Kidney
    If students fail to see the connections among physiological systems, they can become overwhelmed with the amount of information they need to learn. Some students have particular difficulty with the renal system for this reason. This lesson was...
    Lesson
    597

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    90

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    Promoting Interleaved and Spaced Practice in Anatomy and Physiology Students
    Students' academic performance in college can be impacted by varying background experiences and skill levels. This article describes a lesson designed for undergraduate Anatomy and Physiology students to address the challenge instructors face...
    Lesson
    1823

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    377

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    Plotting Cranial and Spinal Nerve Pathways in a Human Anatomy Lab
    Hands-on experiences with cadavers, animal dissections, or plastic models are effective at improving student learning and attitudes in human anatomy courses. The hands-on experience allows students to visualize and experiment with anatomical...
    Lesson
    1039

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    172

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    To Vaccinate or Not to Vaccinate
    To vaccinate or not to vaccinate, that is the question. Much of the recent trend in society against vaccination is that the general population does not understand 1) how vaccines work and 2) how one's vaccination status can influence others....
    Lesson
    2120

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    235

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    The impact of diet and antibiotics on the gut microbiome
    The goal of this article is to describe an active learning exercise that can be used in a variety of advanced microbiology courses, including bacterial physiology, ecology, or systems biology. The gut microbiome is a multi-species bacterial...

    Courses: MicrobiologyMicrobiology

    Lesson
    412

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    32

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    Osmosis Through the Lens of Sexual Health
    Osmosis contributes to a range of biological phenomena, from functioning of nephrons in animals to stomatal opening and closing in plants; yet, scientifically simple ideas about osmosis are common. These ideas limit learners’ comprehension...
    Science Behind the Lesson
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    202

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    The Science Behind the ACTN3 Polymorphism
    A common polymorphism in the alpha-actinin-3 (ACTN3) gene results in the lack of ACTN3 protein expression in fast twitch muscle fibers in ~16% of the human population (1). This genetic change has been linked with muscle performance in humans (2)...
    Lesson
    1654

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    525

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    Doctor in the House: Improving Undergraduate Critical Thinking Skills Through Diagnosing Medical Case Studies
    Students in undergraduate anatomy and physiology courses are not often exposed to clinical examples of homeostatic imbalances, particularly ones that provide an opportunity to diagnose a medical case. We designed a set of medical cases...
    Lesson
    1232

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    373

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    The ACTN3 Polymorphism: Applications in Genetics and Physiology Teaching Laboratories
    Inquiry-based undergraduate laboratories provide the opportunity to engage students in a research experience that improves scientific thinking, but such activities can be difficult to develop and implement due to limited time and resources. We...
    Lesson
    3549

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    263

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    SEAS CURE: Exploring Coral Biology Across Scales
    Complex biological concepts (like symbiosis and coral biology) that span multiple scales and cross disciplinary boundaries are often difficult for students to understand. This complexity is compounded by the challenges inherent to teaching and...
    Lesson
    3036

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    207

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    The Three Sisters of Agriculture: An Active Learning Activity on Symbiotic Nitrogen Fixation
    This active learning exercise introduces students to the plant microbiome and the contributions that bacteria make to plant growth and food production. The Three Sisters are an ancient indigenous practice in which three plant crops and the...

    Courses: MicrobiologyMicrobiology

    Lesson
    2000

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    176

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    Fly Exercise: A Simple Experiment to Test the Physiological Effects of Exercise on a Model Organism
    Model organisms are commonly used to study and experimentally explore biological processes in ways that are technically or ethically not possible in humans. For this reason, model organisms are an essential component of scientific research and...
    Lesson
    1121

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    192

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    It's a bird! It's a plane! It's biomechanics!
    Biomechanics is a discipline that draws from physics and engineering principles to understand the movement and structure of living organisms. It is highly interdisciplinary in nature and can be incorporated into general biology and ecology...
    Lesson
    1149

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    164

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    Using Musical Instruments to Model Negative Feedback in the Hypothalamo-Pituitary-Target Gland Axes
    Homeostasis and negative feedback are crucial, yet difficult, concepts for undergraduates, particularly in the context of the hypothalamo-pituitary axes. This interactive activity was designed to (1) reveal how negative feedback can restore...
    Lesson
    6736

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    264

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    Exploring the City of Biofilms: An Engaging Analogy-Based Activity for Students to Learn Biofilms
    Multicellular biofilms constructed by microbes are key aspects of microbiology with significant implications in various fields, including medicine, environmental science, and biotechnology. While bacteria spend nearly all their lives in biofilms,...

    Courses: MicrobiologyMicrobiology

    Lesson
    2455

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    159

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    What's in this? Students Deliberate on Endocrine Disrupting Chemicals Found in Everyday Healthcare Items to Build Democratic Skills
    In helping our students become informed and active members of society, it is necessary that they develop certain skills that will empower them to improve their community and governance. These skills include communication, collaboration, and...
    Teaching Tools and Strategies
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    128

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    Transitioning Two-Stage Exams to an Online Class
    Students often find biology courses to be very difficult and isolating, particularly if they identify as part of a group that has been historically excluded from STEM. Some of this anxiety and isolation comes from high-stakes exams. We decided to...