CourseSource: Resources

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Role of Crop Genetic Diversity on Pathogen Impact: The Tale of Two Pathogens

Introductory genetics courses are part of the core curriculum in many different fields, including plant breeding, animal science, biology, microbiology, and natural resource management. Concepts involving genes, inheritance, evolution, and genome...

Courses: Introductory Biology Plant Biology Science Process Skills

plant pathologygenetic diversityDisease TriangleModes of Reproduction

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1220

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348

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Mice, Acorns, and Lyme Disease: a Case Study to Teach the Ecology of Emerging Infectious Diseases.

Ebola, Zika, the recall of contaminated lettuce - these are just a few recent outbreaks making headlines. Students should be able to connect what they learn in their biology courses to explain these events happening around them. Unfortunately,...

Courses: Microbiology

epidemiologyEcological changeInfectious disease ecologyReservoirsTransmission cycle

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1340

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145

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Defining and Understanding Pathogenic Disease: An Engaging Activity that Connects Students' Lived Experiences with their Academic Studies

Contagious diseases are unavoidable realities of life. Thus, understanding pathogens and their respective diseases is important in many biological subfields including evolution, ecology, health sciences, microbiology, and others. While all college...

Courses: Ecology Ecology Introductory Biology Microbiology

infectious diseasePathogenspathogenic disease

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857

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172

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From Cre/LoxP to Fate Maps: Inclusive and Equitable Approaches for Engaging Developmental Biology Students in Experimental Design

Engaging first generation underrepresented minority students in the process of inquiry in developmental biology is important to increase diversity in future graduate STEM education. One important challenge is how we design curricula to foster...

Courses: Developmental Biology

experimental designC. elegansCre/LoxPFate mapheart developmentheart regenerationmousereporter constructzebrafish

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2736

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251

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A Muscular Dystrophy Case Study Illustrating the Phenotypic Effects of Mutation

Mutations in genes can lead to a variety of phenotypes, including various human diseases. Students often understand that a particular mutation in a single gene causes a disease phenotype, but it is more challenging to illustrate complex genetic...

Courses: Developmental Biology Genetics

mutationProtein Structureethicscentral dogmahuman disease

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936

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149

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To Vaccinate or Not to Vaccinate

To vaccinate or not to vaccinate, that is the question. Much of the recent trend in society against vaccination is that the general population does not understand 1) how vaccines work and 2) how one's vaccination status can influence others....

Courses: Anatomy-Physiology Biochemistry and Molecular Biology Introductory Biology Microbiology

pathogenELISAimmunityantibodyAntigen

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1859

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838

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Exploration of the Human Genome by Investigation of Personalized SNPs

Students often shy away from tedious bioinformatics approaches to exploring their genomes. However, in our expanding digital world these skills are some of the most relevant and valuable. To increase students' interest in their own genomes, I...

Courses: Bioinformatics Genetics Science Process Skills

UCSC genome browsersingle nucleotide polymorphismGenome wide association studiesGenomic organization

Lesson

2451

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182

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Small Organisms with Big Consequences: Understanding the Microbial World Around Us

Creating a hands-on lab that conveys important information while simultaneously allowing for student autonomy can be difficult. This is particularly true for the field of microbiology, in which labs often rely on “recipe-style”...

Courses: Introductory Biology Microbiology Science Process Skills

disease transmissionmicrobiologymicrobiomeliterature reviewPeer reviewPathogensHealth and WellnessThe Scientific Method

Teaching Tools and Strategies

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98

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Enhancing the Microscopy Skills of Non-Science Majors and Nursing Microbiology Students: Promoting the Practice of Observing Multiple Fields of View Using Blood Smear Slides

One of the challenges in teaching microscopy is having students scan multiple fields of view at high power magnification. Many times, students will feel this unnecessary, especially when presented with slides that show only one structure or a...

Courses: Introductory Biology Microbiology

Microscopy SkillsBlood SmearsBlood Disorders

Lesson

3204

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215

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0

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Garden Variety Mutations: Using Primary Data to Understand the Central Dogma in Large-Lecture Introductory Biology

The ability to interpret and create an argument from data is a crucial skill for budding scientists, yet one that is seldom practiced in introductory courses. During this argumentation module, students in a large lecture class will work in groups...

Courses: Biochemistry and Molecular Biology Genetics Introductory Biology

mutationtranscriptiongene expressioncentral dogmatranslationgel electrophoresisGenotype/Phenotype

LessonPlus

1873

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111

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The Power of Place: A Course-Based Undergraduate Research Experience Studying Urban Ecology, Local Apple Trees and Disease Susceptibility

Course-based Undergraduate Research Experiences (CUREs) offered early in an undergraduate student’s career have the potential to include a greater number and diversity of students than one-on-one mentored research. CUREs that use a...

Courses: Ecology Ecology

Disease ecologyurban ecologyUrban food forestsUrban heat islandsGenetic resistance

Lesson

1607

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555

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A Close-Up Look at PCR

The Polymerase Chain Reaction (PCR) is a fundamental laboratory technique that allows for the amplification of many copies of a desired DNA target sequence. Despite its prevalence, undergraduate students often have poor comprehension about the...

Courses: Biochemistry and Molecular Biology Genetics Introductory Biology Science Process Skills

PCRDNA replication

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3178

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1251

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A CRISPR/Cas Guide RNA Design In Silico Activity

CRISPR biotechnologies inspired by the Clustered Regularly Interspaced Short Palindromic Repeat RNA-guided nuclease adaptive bacterial immune system have revolutionized biology research and become ubiquitous tools for hypothesis and...

Courses: Biochemistry and Molecular Biology Bioinformatics Cell Biology Genetics

bioinformaticsgene expressiongenetic basis of diseaseCRISPR/Cas9genetic engineeringin silico

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4134

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688

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Problem-Based Learning for Physiology: Synthesizing the Cardiovascular System, Respiration, Macronutrient Metabolism, and Renal Function

Problem Based Learning (PBL) is a valuable tool for helping students overcome reliance on memorization by scaffolding opportunities for them to practice the competency of “systems thinking,” which is the ability to understand...

Courses: Anatomy-Physiology

MetabolismObesityblood pressurecardiac functioncardiovascularmetabolic syndromerenalRespirationrespiratory system

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1773

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285

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Interactive Video Vignettes (IVVs) to Help Students Learn Genetics Concepts

Many video resources exist to teach Mendelian genetics, but most consist of passive delivery of information rather than active construction of knowledge by users. We have created two interactive video vignettes (IVVs) that can be used together or...

Courses: Genetics Introductory Biology Science Process Skills

genotypephenotypeallelespedigreedominanceHardy-Weinberg equilibriumInheritance

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Sequences and Properties of Gluten Proteins From Different Grains: A Virtual-Friendly Protein Laboratory

The COVID-19 pandemic has forced much university instruction into virtual modes. As a result, many laboratory courses have either dropped content altogether or replaced hands-on activities with simulations and “dry” labs. Our goal was...

Courses: Biochemistry and Molecular Biology Bioinformatics

protein structure and functionProtein sequenceintermolecular forcesBiomacromolecules

Lesson

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Necessary and Sufficient? Solving the Mystery of the Mitochondrial Pyruvate Transporter

While there are several available lessons for teaching introductory biology students about diffusion, facilitated diffusion, and active transport, fewer materials exist to support upper-division students' understanding of the proteins that...

Courses: Cell Biology

DiffusionActive transportfacilitated diffusionNecessary and sufficientTransport proteins

Lesson

1870

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549

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Using Undergraduate Molecular Biology Labs to Discover Targets of miRNAs in Humans

Incorporating authentic research experiences into undergraduate labs, while shown to be particularly effective at engaging and retaining students in STEM majors, can be difficult to accomplish within the constraints of resource availability or...

Courses: Bioinformatics Genetics Science Process Skills

gene regulationmicroRNAsgene expression

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1579

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Single Cell Insights Into Cancer Transcriptomes: A Five-Part Single-Cell RNAseq Case Study Lesson

There is a growing need for integration of “Big Data” into undergraduate biology curricula. Transcriptomics is one venue to examine biology from an informatics perspective. RNA sequencing has largely replaced the use of microarrays for whole...

Courses: Biochemistry and Molecular Biology Bioinformatics Cell Biology Genetics Introductory Biology

bioinformaticscancertranscriptomicshigh-throughputData wranglingSingle cell RNA sequencingq

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3291

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466

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Splicing it Together: Using Primary Data to Explore RNA Splicing and Gene Expression in Large-Lecture Introductory Biology

At the heart of scientific ways of knowing is the systematic collection and analysis of data, which is then used to propose an explanation of how the world works. In this two-day module, students in a large-lecture course are immersed in a...

Courses: Biochemistry and Molecular Biology Cell Biology Genetics Introductory Biology

gene regulationtranscriptiongene expressioncentral dogmarepressoralternative splicingmRNA processingActivatorTranscription factors

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Role of Crop Genetic Diversity on Pathogen Impact: The Tale of Two Pathogens

Mice, Acorns, and Lyme Disease: a Case Study to Teach the Ecology of Emerging Infectious Diseases.

Defining and Understanding Pathogenic Disease: An Engaging Activity that Connects Students' Lived Experiences with their Academic Studies

From Cre/LoxP to Fate Maps: Inclusive and Equitable Approaches for Engaging Developmental Biology Students in Experimental Design

A Muscular Dystrophy Case Study Illustrating the Phenotypic Effects of Mutation

To Vaccinate or Not to Vaccinate

Exploration of the Human Genome by Investigation of Personalized SNPs

Small Organisms with Big Consequences: Understanding the Microbial World Around Us

Enhancing the Microscopy Skills of Non-Science Majors and Nursing Microbiology Students: Promoting the Practice of Observing Multiple Fields of View Using Blood Smear Slides

Garden Variety Mutations: Using Primary Data to Understand the Central Dogma in Large-Lecture Introductory Biology

The Power of Place: A Course-Based Undergraduate Research Experience Studying Urban Ecology, Local Apple Trees and Disease Susceptibility

A Close-Up Look at PCR

A CRISPR/Cas Guide RNA Design In Silico Activity

Problem-Based Learning for Physiology: Synthesizing the Cardiovascular System, Respiration, Macronutrient Metabolism, and Renal Function

Interactive Video Vignettes (IVVs) to Help Students Learn Genetics Concepts

Sequences and Properties of Gluten Proteins From Different Grains: A Virtual-Friendly Protein Laboratory

Necessary and Sufficient? Solving the Mystery of the Mitochondrial Pyruvate Transporter

Using Undergraduate Molecular Biology Labs to Discover Targets of miRNAs in Humans

Single Cell Insights Into Cancer Transcriptomes: A Five-Part Single-Cell RNAseq Case Study Lesson

Splicing it Together: Using Primary Data to Explore RNA Splicing and Gene Expression in Large-Lecture Introductory Biology

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