CourseSource: Resources

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My Dog IS My Homework: Exploring Canine Genetics to Understand Genotype-Phenotype Relationships

To facilitate understanding of the fundamental genetic concept of the genotype-phenotype relationship in our introductory biology students, we designed an engaging multi-week series of related lessons about canine genetics in which students...

Courses: Bioinformatics Genetics Introductory Biology Science Process Skills

gel electrophoresissequence analysiscanine geneticsdeoxyribonucleic acid (DNA)dog coat morphologygenotype and phenotypemutationsPolymerase chain reaction (PCR)single nucleotide polymorphism (SNP)

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4368

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1259

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What is Speciation, How Does It Occur, and Why Is It Important for Conservation?

Speciation provides a framework for classifying biodiversity on Earth and is a central concept in evolutionary biology. To help undergraduate students learn about speciation, we designed a student-centered lesson that uses active-learning...

Courses: Ecology Ecology Genetics Introductory Biology Science Process Skills

EvolutionconservationGenetic DriftSpeciationNatural SelectionBiological species conceptgene flowMorphological species conceptPhylogenetic species concept

Lesson

2801

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703

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Teaching Biodiversity with Museum Specimens in an Inquiry-Based Lab

In response to the growth of biology datasets and broad efforts to digitize data, an increasingly important skill for science students is the management and analysis of large datasets. We designed an inquiry-based lab module to introduce students...

Courses: Ecology Ecology Evolution Introductory Biology Science Process Skills

data analysisnatural historyphylogenyBiodiversitymammalsAllen's RuleBergmann's Ruleecogeographymuseum research

Lesson

2360

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287

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You and Your Oral Microflora: Introducing non-biology majors to their “forgotten organ”

With limited time available for laboratory activities, introductory science courses for non-science majors typically use the laboratory period to reinforce material that was previously presented during lecture. This practice was true of a human...

Courses: Genetics Introductory Biology Microbiology Science Process Skills

bacteriamicrobiomeBLASTmicrobesDNA replicationPolymerase chain reaction (PCR)

Lesson

1598

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344

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Investigating Gene Expression and Cell Specialization in Axolotl Embryos

The process of cell specialization is critical to the formation and function of tissues in animals and plants. Although gene expression, including the regulation of transcription, is taught in most introductory cell biology courses, the...

Courses: Biochemistry and Molecular Biology Cell Biology Developmental Biology Science Process Skills

developmenttranscriptiongene expressionmodel organismembryo

Teaching Tools and Strategies

2544

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211

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An Interactive Protocol for In-Classroom DNA Extraction

Using commonly available materials, this tool allows students to extract DNA, exploring DNA chemistry and the principles of experimental design and execution. We take a “Choose Your Own Adventure” approach encouraging students to...

Courses: Biochemistry and Molecular Biology Genetics Introductory Biology

geneticsDNAbiochemical structure and function

Lesson

1681

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394

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Who’s That Speci-Mon? Using Pokémon^TM to Understand Biological Terminology Using Greek and Latin Roots

We set out to create a fun and engaging activity using recognizable fictional characters, so students get a chance to practice using Greek and Latin roots to create binomial names. Students in biology courses are faced with a plethora of...

Courses: Anatomy-Physiology Evolution Introductory Biology

linguisticstaxonomyAnatomyGreek and Latin Roots

Lesson

1191

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138

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Understanding the Importance of Microtubules in Normal Cell Division: Chemotherapy Connection

In introductory courses, students learn about microtubules as important structures but may not engage in a hands-on experience to localize microtubules themselves or to learn about their connection to cancer treatment. In this lesson, students...

Courses: Biochemistry and Molecular Biology Cell Biology Genetics

cancerCell DivisionimmunofluorescenceMicrotubulesAntibodies

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3161

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404

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Honoring the Complexity of Genetics: Exploring the Role of Genes and the Environment Using Real World Examples

Historically, undergraduate genetics courses have disproportionately focused on the impact of genes on phenotypes, rather than multifactorial concepts which consider how a combination of genes, the environment, and gene-by-environment interactions...

Courses: Evolution Genetics Introductory Biology

genesenvironmentMendelQuantitative traitsMultifactorialGene by environment interactions

Lesson

2463

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743

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Green Design: How do Leaf Structures Optimize Photosynthesis and Promote Survival?

One of the major learning objectives established by the American Society of Plant Biologists and the Botanical Society of America has students answer the question: How do plant structures enable life functions? This lesson helps students answer...

Courses: Introductory Biology Plant Biology

photosynthesisepidermal layerleaf anatomymesophyllpalisade parenchymaplant anatomyplant structure functionspongy parenchymaStomata

Lesson

1121

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192

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It's a bird! It's a plane! It's biomechanics!

Biomechanics is a discipline that draws from physics and engineering principles to understand the movement and structure of living organisms. It is highly interdisciplinary in nature and can be incorporated into general biology and ecology...

Courses: Anatomy-Physiology Ecology Ecology Evolution

EvolutionecologybatphysiologyAnatomybirdFlightforcesinsect

Lesson

2322

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471

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From Dirt to Streptomyces DNA

The purpose of this semester-long Lesson is to give students an authentic, course-based undergraduate research experience during which they learn basic and advanced microbiological and molecular biology techniques. This project begins with the...

Courses: Microbiology

MetabolismAntibiotic productionrRNA genesSecondary metabolitesStreptomyces

Lesson

1272

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290

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Using a Primary Cell Culture Model to Study the Neural Extracellular Matrix

The extracellular matrix (ECM) provides structural support to cells, but also has key roles in mediating cell adhesion, cell signaling, and differentiation. While this topic is discussed in the lecture setting, it is not heavily studied in...

Courses: Cell Biology Neurobiology

Neural extracellular matrixPerineuronal netPrimary neuronal culture

Lesson

6437

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4115

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CURE-all: Large Scale Implementation of Authentic DNA Barcoding Research into First-Year Biology Curriculum

Growing calls in science education reform have emphasized wide-scale engagement of first-year undergraduate students in authentic research experiences; however, large course enrollments, inadequate student experience, limited resources and...

Courses: Biochemistry and Molecular Biology Bioinformatics Ecology Ecology Evolution Genetics Introductory Biology Science Process Skills

phylogeneticsbioinformaticsBiodiversityprocess of sciencetaxonomyPCRDNADNA sequencegel electrophoresis

Lesson

2644

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460

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Go Extinct! An Award-Winning Evolution Game That Teaches Tree-Thinking as Students Pursue the Winning Strategy

Evolutionary trees communicate both the diversity and unity of life, a central and important scientific concept, as highlighted by the Vision and Change undergraduate biology education movement. Evolutionary trees and cladograms are diagrams...

Courses: Evolution

phylogeneticsnatural historyBiodiversitycladogramCommon ancestorEvolutionary treeLand vertebratesMonophyletic cladeTetrapods

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763

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Using Yeast to Make Scientists: A Six-Week Student-Driven Research Project for the Cell Biology Laboratory

Traditionally-trained undergraduate students often lack an understanding of science as an active process that yields the information presented in their textbooks. One result has been a call for more research experiences built into traditional...

Courses: Cell Biology Science Process Skills

yeastgrowth curvecell proliferationviability

Lesson

459

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37

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Adapting a Traditional Laboratory Exercise to Become Inquiry Based: An Example With an Introductory Biology Lab in Diffusion

Authentic research experiences are effective in fostering self-efficacy and increasing retention in STEM, particularly among minoritized student populations. Many instructors have sought to bring these to a wide range of students in the form of...

Courses: Introductory Biology Science Process Skills

protocolquestionDiffusionVariableshypothesisscience processcontrolscientific efficacy

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Using Images of Foraging Leaf-Cutter Ants to Teach Linear Regression

This lesson offers students a realistic, open-inquiry research experience, even when lab or field research is not possible. We first introduce students to leaf-cutter ants and how they forage. Then we provide images and videos of foraging...

Courses: Ecology Ecology Introductory Biology Science Process Skills

linear regressionexperimental designPlant-insect interactionsSymbiosisForaging behavior

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1649

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317

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Differential Gene Expression during Xenopus laevis Development

In Developmental Biology classes, students are challenged with understanding how differential gene expression guides embryonic development. It can be difficult for students to realize that genes need to be turned on or off at the right time and...

Courses: Developmental Biology

gene expressionXenopusearly developmentembryofertilizationin situ hybridization

Lesson

3549

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263

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SEAS CURE: Exploring Coral Biology Across Scales

Complex biological concepts (like symbiosis and coral biology) that span multiple scales and cross disciplinary boundaries are often difficult for students to understand. This complexity is compounded by the challenges inherent to teaching and...

Courses: Anatomy-Physiology Cell Biology Ecology Ecology Introductory Biology Science Process Skills

microscopyAnatomySymbiosisMetabolismbleachinginvertebratedinoflagellate

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My Dog IS My Homework: Exploring Canine Genetics to Understand Genotype-Phenotype Relationships

What is Speciation, How Does It Occur, and Why Is It Important for Conservation?

Teaching Biodiversity with Museum Specimens in an Inquiry-Based Lab

You and Your Oral Microflora: Introducing non-biology majors to their “forgotten organ”

Investigating Gene Expression and Cell Specialization in Axolotl Embryos

An Interactive Protocol for In-Classroom DNA Extraction

Who’s That Speci-Mon? Using Pokémon^TM to Understand Biological Terminology Using Greek and Latin Roots

Understanding the Importance of Microtubules in Normal Cell Division: Chemotherapy Connection

Honoring the Complexity of Genetics: Exploring the Role of Genes and the Environment Using Real World Examples

Green Design: How do Leaf Structures Optimize Photosynthesis and Promote Survival?

It's a bird! It's a plane! It's biomechanics!

From Dirt to Streptomyces DNA

Using a Primary Cell Culture Model to Study the Neural Extracellular Matrix

CURE-all: Large Scale Implementation of Authentic DNA Barcoding Research into First-Year Biology Curriculum

Go Extinct! An Award-Winning Evolution Game That Teaches Tree-Thinking as Students Pursue the Winning Strategy

Using Yeast to Make Scientists: A Six-Week Student-Driven Research Project for the Cell Biology Laboratory

Adapting a Traditional Laboratory Exercise to Become Inquiry Based: An Example With an Introductory Biology Lab in Diffusion

Using Images of Foraging Leaf-Cutter Ants to Teach Linear Regression

Differential Gene Expression during Xenopus laevis Development

SEAS CURE: Exploring Coral Biology Across Scales

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