CourseSource: Resources

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How Do Kidneys Make Urine From Blood? Qualitative and Quantitative Approaches to Filtration, Secretion, Reabsorption, and Excretion

The function of the kidneys is to help maintain a constant internal environment (homeostasis) by regulating the volume and chemical composition of the blood. This regulation occurs via three fundamental processes: filtration, secretion, and...

Courses: Anatomy-Physiology Introductory Biology

collecting ductexcretionglomerular filtration rate (GFR)nephron tubulereabsorptionrenal corpusclesection

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980

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My Fish Tank: An Active Learning Activity for Bacterial Nitrogen Metabolism

This active learning activity introduces students to the second part of the nitrogen cycle, nitrification. In terrestrial and aquatic environments, bacteria from the Nitrosomonas and Nitrobacter genera oxidize ammonia first to nitrite (via a...

Courses: Biochemistry and Molecular Biology Ecology Ecology Microbiology

nitrogen cyclenitrificationnitrifying bacteria

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1684

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Taking the Hassle out of Hasselbalch

Mention pH in a classroom and you can almost see the inner yawn on the faces of your students. The definition may even roll easily from their lips. However, despite multiple exposures to the relationship of pH and pKa throughout a typical...

Courses: Biochemistry and Molecular Biology Science Process Skills

pHdrug uptakeHenderson-Hasslbalch equationmedical applicationspKa

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1879

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Engaging Students in Pharmacogenetics: Patient Case Studies Using the PharmGKB Website

Cytochrome P450 (CYP) enzymes are important regulators of drug efficacy and toxicity. Genetic variation in CYP isoforms can impact how well patients respond to medications or experience unwanted toxicities. PharmGKB is an online pharmacogenomics...

Courses: Genetics Toxicology

toxicologyPharmacologydrug metabolismpharmacodynamicspharmacogenetics

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2124

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The impact of diet and antibiotics on the gut microbiome

The goal of this article is to describe an active learning exercise that can be used in a variety of advanced microbiology courses, including bacterial physiology, ecology, or systems biology. The gut microbiome is a multi-species bacterial...

Courses: Microbiology

microbiomeenvironmental controlhost responsemetabolites