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    Teaching Tools and Strategies
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    "Boost your evolution IQ": An evolution misconceptions game
    Students often enter introductory biology courses with misconceptions about evolution. For example, many students believe that traits arise when a species needs them or that evolutionary processes are goal-oriented. To address these and other...

    Courses: EvolutionEvolution

    Evolutionactive learningNatural Selectiongroup workmisconceptions
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    475

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    A Lesson on Matter and Energy at the Organismal Scale: Linking Patterns and Processes Across Diverse Taxa
    Pathways and transformations of energy and matter (PTEM) are a conceptually challenging but essential component of biological literacy. Curricular gaps about PTEM nevertheless remain; although lessons targeting PTEM at small scales (chemical,...

    Courses: EcologyEcology Introductory BiologyIntroductory Biology

    plantsenergyAnimalsfungimatterorganismal scale
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    866

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    Exploring the Complexities of Photosynthesis Through a Comic Strip
    Photosynthesis is a conceptually challenging topic. The small scale at which photosynthesis takes place makes it difficult for students to visualize what is occurring, and students are often overwhelmed by all of the details of the process. This...

    Courses: Introductory BiologyIntroductory Biology Plant BiologyPlant Biology

    photosynthesislight-dependent reactionsCalvin cyclechloroplast
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    405

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    It's a Substrate... It's a Protein...No - It's an Enzyme! Teaching Using 3D Serine Protease Physical Modeling Activities to Confront Misconceptions.
    Reported misconceptions of enzyme-substrate interactions highlight the necessity for better, targeted instructional tools and assessments. A series of active learning activities with corresponding three-dimensional (3D) physical models were...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology

    Protein StructureEnzymes-Substrate InteractionsNoncovalent InteractionsGeometric ComplementaryElectronicsStereochemistrySerine Proteases
    Essay
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    369

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    Online Adaptation of the Cell Engineer/Detective Lesson
    One of the most fundamental themes of biology is the relationship between structure and function, which is particularly evident when it comes to cells; however, the traditional cartoon depictions of cells that are often used to help teach the...

    Courses: Cell BiologyCell Biology Introductory BiologyIntroductory Biology Science Process SkillsScience Process Skills

    cell functionCell StructureOrganelles
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    453

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    Moths and Frogs and E. coli, Oh My!: Agent-based Modeling of Evolutionary Systems
    In evolution classrooms, introducing and reinforcing the idea of genetic drift and random selection can be challenging, as can be reinforcing appropriate mental models of evolution. Agent-based models offer students the opportunity to conduct a...

    Courses: BioinformaticsBioinformatics EcologyEcology EvolutionEvolution Science Process SkillsScience Process Skills

    modelingEvolutionecologyagent-based modelingGenetic Driftenvironmental scienceNatural Selectioncompetitive coevolutionsimulation modelingevolutionary reasoning
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    513

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    Using Pathway Maps to Link Concepts, Peer Review, Primary Literature Searches and Data Assessment in Large Enrollment Classes: An example from teaching ecosystem ecology
    As with many other complex topics, teaching ecosystem ecology can be particularly difficult in terms of helping students understand the relationships between the various component parts. We addressed this challenge in a general ecology course by...

    Courses: EcologyEcology Introductory BiologyIntroductory Biology Science Process SkillsScience Process Skills

    energyecosystemNutrientsPathway
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    502

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    Targeting Misconceptions in the Central Dogma by Examining Viral Infection
    Understanding the central dogma and how changes in gene expression can impact cell function requires integration of several topics in molecular biology. Students often do not make the necessary connections between DNA structure, transcription,...

    Courses: GeneticsGenetics Introductory BiologyIntroductory Biology

    datatranscriptionvirustranslationprotein functionmembrane transportPredictions
    Teaching Tools and Strategies
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    394

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    The Flight Physics Concept Inventory: Reliably Evaluating Aerodynamic Lift, Drag and Associated (Naïve) Concepts of Flight in Class and In-Game
    Students often struggle to transfer conceptual understanding from isolated instruction to a coherent mental model. This is especially true for the context of flight physics, fluid dynamics, or the concepts of aerodynamic lift, drag, stall, center...

    Courses: Introductory Physics: Calculus-BasedIntroductory Physics: Calculus-Based

    active learninggamificationmisconceptionsaerodynamicsfluid dynamicsResearch-based assessment instrumentConceptual SurveyPRE-/POST-test
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    Introducing Immunology Research Literature to Understand B-cell Receptor Gene Expression
    Immunology is relevant to our everyday lives, driving a need for more engaging and inclusive undergraduate immunology education. One way to engage a diverse group of learners is by teaching them how to read and interpret the scientific literature....

    Courses: ImmunologyImmunology Science Process SkillsScience Process Skills

    recombinationantibodyV(D)J recombinationB-cell receptorlymphocyte receptor
    Teaching Tools and Strategies
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    A How to Guide and Template for Designing a Puzzle Based Escape Room Game
    Educational games are one active and effective way of engaging students with material while also providing additional motivation to tackle challenging concepts. A particularly popular game concept is the escape room, where students need to work in...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology BioinformaticsBioinformatics EcologyEcology EvolutionEvolution GeneticsGenetics Science Process SkillsScience Process Skills

    Problem SolvingCollaborative WorkCorrect Misconceptions
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    Tying it All Together: An Activity to Help Students Connect Course Experiences to Posted Learning Outcomes
    Instructors of undergraduate courses in Biology and other Science, Technology, Engineering, and Mathematics (STEM) disciplines face an ongoing challenge to foster higher-order thinking and learning skills while also developing a sound conceptual...

    Courses: Anatomy-PhysiologyAnatomy-Physiology BioinformaticsBioinformatics Cell BiologyCell Biology Developmental BiologyDevelopmental Biology EcologyEcology GeneticsGenetics Introductory BiologyIntroductory Biology MicrobiologyMicrobiology NeurobiologyNeurobiology Plant BiologyPlant Biology Science Process SkillsScience Process Skills

    metacognitionreflectiongoalsOutcomes
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    Generating Biological Hypotheses in a "Course-based Undergraduate Research Experience"(CURE) Course
    Hypotheses are often incorrectly defined as educated guesses or if/then statements. Further confusion arises from the fact that not all disciplines define hypotheses similarly. The difficulty in distinguishing between statistical and biological...

    Courses: Science Process SkillsScience Process Skills

    scientific methodHPT axisNeural stem cells
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    275

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    Application of a Bacterial Experimental Evolution System to Visualize and Teach Evolution in Action: A Course-Based Undergraduate Research Experience
    Concepts of evolution are typically taught through examples of extremely long timescales, which do not always resonate broadly. Here, we describe a course-based undergraduate research experience tailored for junior and senior undergraduate biology...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology BioinformaticsBioinformatics Cell BiologyCell Biology EvolutionEvolution GeneticsGenetics MicrobiologyMicrobiology

    EvolutionmutationcompetitionNatural Selectionregulationstructure and functionreproductive fitnessgenotype to phenotypehomologs
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    448

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    Teaching Advanced Concepts in Regulation of the Lac Operon With Modeling and Simulation
    Success in biochemistry and other life science courses requires that students understand important biological concepts. One of these concepts is how gene regulation ensures that homeostasis is maintained in an organism. The lac operon is a...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology

    gene regulationinducible operonProkaryotic cellPhosphoenolpyruvate transferase system (PTS)
    Teaching Tools and Strategies
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    Preparing Student Study Guides through Peer Collaboration in the Technological Era
    Incorporating active learning exercises into large lecture courses is particularly challenging, especially when it comes to examination preparation materials. Traditionally, study guides are used as a tool to guide student learning and review...

    Courses: Introductory BiologyIntroductory Biology Professional Development and Career PlanningProfessional Development and Career Planning Science Process SkillsScience Process Skills

    active learningDiscussionStudy Skills
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    A Kinesthetic Modeling Activity to Teach PCR Fundamentals
    Most molecular biology and biological sciences students understand that the polymerase chain reaction (PCR) is used to amplify DNA. However, we have found that some students experience conceptual misunderstandings, a lack of detailed comprehension...

    Courses: GeneticsGenetics Science Process SkillsScience Process Skills

    PCR
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    Does Organelle Shape Matter?: Exploring Patterns in Cell Shape and Structure with High-Throughput (HT) Imaging
    Organelle structure has been studied and visualized for decades; however, publicly available databases that use improved high-throughput microscopy of gene-edited cell lines have recently revolutionized the amount and quality of information now...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology BioinformaticsBioinformatics Cell BiologyCell Biology GeneticsGenetics Science Process SkillsScience Process Skills

    modelingcase studymicroscopystructureOrganellesHigh-throughput (HT)Endoplasmic Reticulum (ER)Fluorescent microscopyHuman Cell Biology
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    Investigating Enzyme Structure and Function Through Model-Building and Peer Teaching in an Introductory Biology Course
    A foundational knowledge of the relationship between structure and function is critical to understanding how enzymes work. The seemingly invisible nature of these molecular interactions makes it challenging for undergraduate students to...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology Introductory BiologyIntroductory Biology

    structure-functionEnzymeallosteric regulationcompetitive inhibitionfeedback inhibitionnoncompetitive inhibitionproductsubstrate
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    Evaluating the Quick Fix: Weight Loss Drugs and Cellular Respiration
    One key to student success in introductory and cell biology courses is a foundational knowledge of cellular respiration. This is a content area in which students often harbor misconceptions that make cellular respiration particularly challenging...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology Cell BiologyCell Biology Introductory BiologyIntroductory Biology

    data analysisCellular RespirationElectron Transport ChainEnergy transformationsMitochondriaOxidative phosphorylationWeight loss drugs24-dinitrophenol (DNP)