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    Using Musical Instruments to Model Negative Feedback in the Hypothalamo-Pituitary-Target Gland Axes
    Homeostasis and negative feedback are crucial, yet difficult, concepts for undergraduates, particularly in the context of the hypothalamo-pituitary axes. This interactive activity was designed to (1) reveal how negative feedback can restore...
    Lesson
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    The Comics Project: Synthesizing and Communicating Science with Comics
    Students, especially non-science majors, often see science as abstracted from their daily lives. Moreover, students often struggle to translate scientific concepts into everyday language in order to communicate to their communities what they have...
    Lesson
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    Cell Signaling Pathways - a Case Study Approach
    Signaling and gene expression are fundamental to cell biology and developmental biology. Although these topics are highly interrelated, they typically appear in separate units in a course. We use a series of short problem-based learning exercises...
    Lesson
    1358

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    513

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    Using Pathway Maps to Link Concepts, Peer Review, Primary Literature Searches and Data Assessment in Large Enrollment Classes: An example from teaching ecosystem ecology
    As with many other complex topics, teaching ecosystem ecology can be particularly difficult in terms of helping students understand the relationships between the various component parts. We addressed this challenge in a general ecology course by...
    Lesson
    2973

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    612

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    Using Synthetic Biology and pClone Red for Authentic Research on Promoter Function: Introductory Biology (identifying new promoters)
    Students often memorize the definition of a transcriptional promoter but fail to fully understand the critical role promoters play in gene expression. This laboratory lesson allows students to conduct original research by identifying and...
    Lesson
    1752

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    603

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    Student-Driven Design-and-Improve Modules to Explore the Effect of Plant Bioactive Compounds in Three Model Organisms
    Engaging and supporting introductory level students in authentic research experiences during required coursework is challenging. Plant bioactive compounds attract students' natural curiosity as they are found in many familiar items such as...
    Lesson
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    CRISPR/Cas9 in yeast: a multi-week laboratory exercise for undergraduate students
    Providing undergraduate life-science students with a course-based research experience that utilizes cutting-edge technology, is tractable for students, and is manageable as an instructor is a challenge. Here, I describe a multi-week lesson plan...
    Lesson
    2050

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    517

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    A Simple Method for Predicting a Molecule's Biological Properties From Its Polarity
    The distinction between very polar and less polar substances is a foundation of biochemistry, cell biology, and physiology; it surfaces in multiple concept inventories and elaborations of biological core concepts. However, in our experience, most...
    Lesson
    459

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    37

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    Adapting a Traditional Laboratory Exercise to Become Inquiry Based: An Example With an Introductory Biology Lab in Diffusion
    Authentic research experiences are effective in fostering self-efficacy and increasing retention in STEM, particularly among minoritized student populations. Many instructors have sought to bring these to a wide range of students in the form of...
    Lesson
    1651

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    244

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    Make It Stick: Teaching Gene Targeting with Ribbons and Fasteners
    Manipulating gene expression is a commonly used tool to study the effect of a single gene or the hierarchy of gene networks in many different biological disciplines. When working with mice, the most commonly used techniques to manipulate genes...
    Lesson
    2685

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    123

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    Film as a Powerful Tool for Increasing Awareness of the Importance of Belonging in STEM
    People of color in STEM fields can face a variety of challenges with belonging due to structural, cultural, psychological, and institutional barriers. The professional development sessions described in this lesson involved using film as well as...
    Lesson
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    Lights, Camera, Acting Transport! Using role-play to teach membrane transport
    Lights, Camera, Acting Transport! is an active and unique role-play exercise designed to teach introductory biology students basic concepts of passive and active membrane transport. The activity involves three acts in which students, representing...
    Lesson
    240

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    21

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    Protein Import Into the ER: Understanding Experimental Methods for Old and New Cellular Discoveries
    Process Oriented Guided Inquiry Learning (POGIL) is an effective approach for group work in STEM courses. POGIL-style lessons foster active learning because they require students to communicate and co-construct knowledge to solve problems. Here,...
    Lesson
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    467

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    Ain't No Mountain Pine Enough: A Case Study of How Mountain Pine Beetles are Affecting Ecosystem Processes
    This case study engages students in generating hypotheses and predictions, analyzing and interpreting data, critically evaluating contrasting results in science, and thinking about feedbacks between biota and abiotic ecosystem dynamics. To address...

    Courses: EcologyEcology

    Lesson
    2982

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    349

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    Serotonin in the Pocket: Non-covalent interactions and neurotransmitter binding
    This lesson introduces beginning biochemistry students to the concept of a biomolecule binding site, such as a neurotransmitter receptor site or an enzyme active site. A simple organic molecule, the neurotransmitter serotonin, is the focus of the...
    Lesson
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    Why Do I Need a Lab Notebook? Teaching Responsible Conduct of Research with CURE Lab Notebooks
    There are few instructional tools about data acquisition and management available for undergraduate students. I created this lesson as a Fellow of the Ethics Network for Course-Based Opportunities in Undergraduate Research (ENCOUR) to fill this...
    Lesson
    2285

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    Discovering Prokaryotic Gene Regulation by Building and Investigating a Computational Model of the lac Operon
    The ability to construct and reason through a biological system is an important skill to develop in science education. This level of understanding forces students to recognize the interrelatedness of components within a biological process and...
    Lesson
    990

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    137

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    BioMap Degree Plan: A project to guide students in exploring, defining, and building a plan to achieve career goals
    Traditional college students begin their academic journey with a variety of ideas about the careers they might ultimately pursue. Some students have always known what they want to do, some have ideas about possible careers, while others have never...
    Lesson
    2961

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    216

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    Advancing Global Learning Through a Collaborative Online International Learning (COIL) Module on the United Nations Sustainable Development Goals (UN SDGs)
    An increasingly interconnected world presents opportunities for globally relevant curricula in the classroom. Implementing collaborative online international learning (COIL) modules within medium-sized courses can take advantage of this...
    Lesson
    1305

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    Tying it All Together: An Activity to Help Students Connect Course Experiences to Posted Learning Outcomes
    Instructors of undergraduate courses in Biology and other Science, Technology, Engineering, and Mathematics (STEM) disciplines face an ongoing challenge to foster higher-order thinking and learning skills while also developing a sound conceptual...