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    An Open Source, Collaborative Electronic Notebook for Undergraduate Laboratory Classes
    To overcome many of the limitations of the paper laboratory notebook (PLN), we developed an electronic laboratory notebook (e-LN) for the Dynamic Genome course at the University of California. The Dynamic Genome course is an authentic research...

    Courses: Science Process SkillsScience Process Skills

    data collectionData annotationNotebook Skills
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    Hands-On, Hands-Off: The Community College Genomics (ComGen) Course-Based Undergraduate Research Experience
    Science is a process of discovery where failure is inherent and iteration is necessary, yet instructors often teach the scientific process as if it is a controlled, highly supervised, confirmatory practice of following directions to get a known...

    Courses: Cell BiologyCell Biology GeneticsGenetics

    geneticssequencingDNAbacterium
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    Dilution and Pipetting Lesson Using Food Dyes
    In this lesson students learn how to use micropipettors to accurately measure small volumes of liquids and perform dilutions using food dyes. Students dilute four food dyes at 10X concentration to 1X working stocks. Using the formula c1v1=c2v2...

    Courses: Science Process SkillsScience Process Skills

    dilutionCalculationLab SkillsMicropipetting
    Teaching Tools and Strategies
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    Converting a Face-to-Face Lab to Online: An Example of Process and Outcomes for a CRISPR-Based Molecular Biology Lab
    The COVID-19 pandemic created a need to convert in-person laboratory courses into an online format in a short amount of time. For this reason, we converted our face-to-face molecular biology lab course to an online version in Spring 2020. The lab...

    Courses: GeneticsGenetics Science Process SkillsScience Process Skills

    mutationtranscriptioncrisprtranslation
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    406

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    A flexible, multi-week approach to plant biology - How will plants respond to higher levels of CO2?
    To help introductory biology students understand how plants will respond to higher levels of CO2, we have created a multi-week module consisting of a series of four related laboratory lessons. These lessons allow students to make connections among...

    Courses: Introductory BiologyIntroductory Biology Plant BiologyPlant Biology

    statisticsplantsphotosynthesiscarbon dioxidecommunicating sciencegroup workResource AllocationRespirationStomata
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    The Developmental Origins of Mythology: A Pandemic-Inspired Innovative Developmental Biology Laboratory Exercise
    From an experiential, hands-on perspective, the Developmental Biology Laboratory is easily amenable to a wide range of undergraduate-friendly experiments. Thus, pivoting to a virtual laboratory during the COVID-19 pandemic required significant...

    Courses: Developmental BiologyDevelopmental Biology

    gastrulationaxis formationlimb developmentchimeramidline
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    CURE-all: Large Scale Implementation of Authentic DNA Barcoding Research into First-Year Biology Curriculum
    Growing calls in science education reform have emphasized wide-scale engagement of first-year undergraduate students in authentic research experiences; however, large course enrollments, inadequate student experience, limited resources and...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology BioinformaticsBioinformatics EcologyEcology EvolutionEvolution GeneticsGenetics Introductory BiologyIntroductory Biology Science Process SkillsScience Process Skills

    phylogeneticsbioinformaticsBiodiversityprocess of sciencetaxonomyPCRDNADNA sequencegel electrophoresis
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    CRISPR/Cas9 in yeast: a multi-week laboratory exercise for undergraduate students
    Providing undergraduate life-science students with a course-based research experience that utilizes cutting-edge technology, is tractable for students, and is manageable as an instructor is a challenge. Here, I describe a multi-week lesson plan...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology BioinformaticsBioinformatics GeneticsGenetics MicrobiologyMicrobiology Science Process SkillsScience Process Skills

    bioinformaticsPCRphenotypingCRISPR/Cas9gene editingcloningGenotypingRestriction enzyme
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    A CURE for Salmonella: A Laboratory Course in Pathogen Microbiology and Genomics
    Rapid advances in genomics and bioinformatics, the vast amount of data generated by next-generation sequencing, and the penetration of the ‘-omics’ into many areas of biology have created a need for students with hands-on experience with...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology BioinformaticsBioinformatics EcologyEcology MicrobiologyMicrobiology

    epidemiologyresearchbioinformaticsgenomicspublic healthAntibiotic Resistant BacteriaSalmonellaDNA sequencingpathogenic bacteria
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    My Dog IS My Homework: Exploring Canine Genetics to Understand Genotype-Phenotype Relationships
    To facilitate understanding of the fundamental genetic concept of the genotype-phenotype relationship in our introductory biology students, we designed an engaging multi-week series of related lessons about canine genetics in which students...

    Courses: BioinformaticsBioinformatics GeneticsGenetics Introductory BiologyIntroductory Biology Science Process SkillsScience Process Skills

    gel electrophoresissequence analysiscanine geneticsdeoxyribonucleic acid (DNA)dog coat morphologygenotype and phenotypemutationsPolymerase chain reaction (PCR)single nucleotide polymorphism (SNP)
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    Differential Gene Expression during Xenopus laevis Development
    In Developmental Biology classes, students are challenged with understanding how differential gene expression guides embryonic development. It can be difficult for students to realize that genes need to be turned on or off at the right time and...

    Courses: Developmental BiologyDevelopmental Biology

    gene expressionXenopusearly developmentembryofertilizationin situ hybridization
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    Assessing Urban Biodiversity With the eBird Citizen Science Project: A Course-Based Undergraduate Research Experience (CURE) Module
    The eBird citizen science module takes advantage of technology tools and online resources developed by the Cornell Laboratory of Ornithology (http://ebird.org) to achieve several learning objectives embedded in a semester-long upper-level biology...

    Courses: EcologyEcology Science Process SkillsScience Process Skills

    datacitizen sciencecommunityBiodiversitySpecieshypothesishabitat
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    Investigating Gene Expression and Cell Specialization in Axolotl Embryos
    The process of cell specialization is critical to the formation and function of tissues in animals and plants. Although gene expression, including the regulation of transcription, is taught in most introductory cell biology courses, the...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology Cell BiologyCell Biology Developmental BiologyDevelopmental Biology Science Process SkillsScience Process Skills

    developmenttranscriptiongene expressionmodel organismembryo
    LessonPlus
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    The Power of Place: A Course-Based Undergraduate Research Experience Studying Urban Ecology, Local Apple Trees and Disease Susceptibility
    Course-based Undergraduate Research Experiences (CUREs) offered early in an undergraduate student’s career have the potential to include a greater number and diversity of students than one-on-one mentored research. CUREs that use a...

    Courses: EcologyEcology

    Disease ecologyurban ecologyUrban food forestsUrban heat islandsGenetic resistance
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    Using CRISPR-Cas9 to teach the fundamentals of molecular biology and experimental design
    One of the challenges of inquiry-based research experiences is balancing the instruction on skills and techniques with data generation and analysis. This is especially true in technique heavy disciplines such as molecular biology, where emphasis...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology

    experimental designcrisprmolecular technique
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    Dynamic Daphnia: An inquiry-based research experience in ecology that teaches the scientific process to first-year biologists
    This authentic research experience lesson teaches the core concept of systems and the competencies of quantitative reasoning, communication, and the ability to apply science. The research is student driven, the results are unknown, and the...

    Courses: EcologyEcology Introductory BiologyIntroductory Biology Science Process SkillsScience Process Skills

    statisticsecologyscientific methodexperimental designAbiotic and Biotic FactorsDependent and Independent Variables
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    Using Zebrafish in a Developmental Biology Lab Course to Explore Interactions Between Development and the Environment
    Important learning outcomes for biology students include the ability to develop experiments as well as pull together concepts across their coursework. The field of developmental biology, especially environmental influences on development...

    Courses: Developmental BiologyDevelopmental Biology Science Process SkillsScience Process Skills

    toxicologymorphogenesisorganogenesis
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    Follow the Sulfur: Using Yeast Mutants to Study a Metabolic Pathway
    Students are frequently overwhelmed by the complexity of metabolic pathways and they think they have "learned" the pathway when they have memorized the individual reactions.  This laboratory lesson helps students to understand the...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology GeneticsGenetics Introductory BiologyIntroductory Biology MicrobiologyMicrobiology Science Process SkillsScience Process Skills

    SelectionyeastMetabolismcysteinemediamethioninemutantPathwaysulfur
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    Data Analysis Recitation Activities Support Better Understanding in SEA-PHAGES CURE
    Course-based undergraduate research experiences (CUREs) are widely known to improve student learning outcomes in the sciences. Undergraduate students have a particularly difficult time interpreting the scientific data that they generate in these...

    Courses: Science Process SkillsScience Process Skills

    bacteriophageDNA extractionGel analysisPhage purificationTiter calculationViral replicative growth
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    Using Yeast to Make Scientists: A Six-Week Student-Driven Research Project for the Cell Biology Laboratory
    Traditionally-trained undergraduate students often lack an understanding of science as an active process that yields the information presented in their textbooks. One result has been a call for more research experiences built into traditional...

    Courses: Cell BiologyCell Biology Science Process SkillsScience Process Skills

    yeastgrowth curvecell proliferationviability