CourseSource: Resources

Teaching Tools and Strategies

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Enhancing the Microscopy Skills of Non-Science Majors and Nursing Microbiology Students: Promoting the Practice of Observing Multiple Fields of View Using Blood Smear Slides

One of the challenges in teaching microscopy is having students scan multiple fields of view at high power magnification. Many times, students will feel this unnecessary, especially when presented with slides that show only one structure or a...

Courses: Introductory Biology Microbiology

Microscopy SkillsBlood SmearsBlood Disorders

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1672

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314

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Understanding Host-Pathogen Interactions With the Use of Galleria mellonella

The Galleria mellonella; the larvae of the Greater Wax Moth, is a safe and effective means to study host-pathogen interactions in the undergraduate setting. The use of animal models in the teaching classroom provides an opportunity to discuss...

Courses: Immunology Microbiology

innate immunitybacterial pathogenesisHost-pathogen interactionsGalleria mellonellaVirulence

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1403

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385

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Mice, Acorns, and Lyme Disease: a Case Study to Teach the Ecology of Emerging Infectious Diseases.

Ebola, Zika, the recall of contaminated lettuce - these are just a few recent outbreaks making headlines. Students should be able to connect what they learn in their biology courses to explain these events happening around them. Unfortunately,...

Courses: Microbiology

epidemiologyEcological changeInfectious disease ecologyReservoirsTransmission cycle

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458

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Small Organisms with Big Consequences: Understanding the Microbial World Around Us

Creating a hands-on lab that conveys important information while simultaneously allowing for student autonomy can be difficult. This is particularly true for the field of microbiology, in which labs often rely on “recipe-style”...

Courses: Introductory Biology Microbiology Science Process Skills

disease transmissionmicrobiologymicrobiomeliterature reviewPeer reviewPathogensHealth and WellnessThe Scientific Method

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1235

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A CURE for Salmonella: A Laboratory Course in Pathogen Microbiology and Genomics

Rapid advances in genomics and bioinformatics, the vast amount of data generated by next-generation sequencing, and the penetration of the ‘-omics’ into many areas of biology have created a need for students with hands-on experience with...

Courses: Biochemistry and Molecular Biology Bioinformatics Ecology Ecology Microbiology

epidemiologyresearchbioinformaticsgenomicspublic healthAntibiotic Resistant BacteriaSalmonellaDNA sequencingpathogenic bacteria

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My Fish Tank: An Active Learning Activity for Bacterial Nitrogen Metabolism

This active learning activity introduces students to the second part of the nitrogen cycle, nitrification. In terrestrial and aquatic environments, bacteria from the Nitrosomonas and Nitrobacter genera oxidize ammonia first to nitrite (via a...

Courses: Biochemistry and Molecular Biology Ecology Ecology Microbiology

nitrogen cyclenitrificationnitrifying bacteria

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459

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Antibiotic Resistance Genes Detection in Environmental Samples

Our aim is to provide an authentic research experience for undergraduate students in a variety of biology courses through collaboration between a four-year university and a community college. This lab series teaches transferable and universal...

Courses: Introductory Biology Microbiology Science Process Skills

geneticsenvironmentmicrobiologyUndergraduateantibiotic-resistancePCRgel electrophoresisauthentic inquiry

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From Dirt to Streptomyces DNA

The purpose of this semester-long Lesson is to give students an authentic, course-based undergraduate research experience during which they learn basic and advanced microbiological and molecular biology techniques. This project begins with the...

Courses: Microbiology

MetabolismAntibiotic productionrRNA genesSecondary metabolitesStreptomyces

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641

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Follow the Sulfur: Using Yeast Mutants to Study a Metabolic Pathway

Students are frequently overwhelmed by the complexity of metabolic pathways and they think they have "learned" the pathway when they have memorized the individual reactions. This laboratory lesson helps students to understand the...

Courses: Biochemistry and Molecular Biology Genetics Introductory Biology Microbiology Science Process Skills

SelectionyeastMetabolismcysteinemediamethioninemutantPathwaysulfur

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4348

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84

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The Great Petunia Carnage of 2017: A Clicker Case Study Using Petunias to Describe the Effect of Genetic Modification on the Biochemistry of Flower Color and Phenotype in Plants

In this single class period case study, students examine the difference between genotype and phenotype by studying the mechanisms by which commercially available petunias have been bred to have different phenotypes (flower colors). Students review...

Courses: Genetics Introductory Biology Plant Biology

case studyGenetic ModificationsBiochemistry of Flower ColorGMO regulationsGenotype-Phenotype Connections

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287

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You and Your Oral Microflora: Introducing non-biology majors to their “forgotten organ”

With limited time available for laboratory activities, introductory science courses for non-science majors typically use the laboratory period to reinforce material that was previously presented during lecture. This practice was true of a human...

Courses: Genetics Introductory Biology Microbiology Science Process Skills

bacteriamicrobiomeBLASTmicrobesDNA replicationPolymerase chain reaction (PCR)

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301

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Using QIIME to Interpret Environmental Microbial Communities in an Upper Level Metagenomics Course

Metagenomics is rapidly evolving due to advances in sequencing technologies and bioinformatics, but without proper training to interpret these datasets, student understanding remains limited. Aimed at undergraduate juniors and seniors and graduate...

Courses: Biochemistry and Molecular Biology Bioinformatics Ecology Ecology Microbiology Science Process Skills

microbiome

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562

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Manuscript 101: A Data-Driven Writing Exercise for Beginning Scientists

Learning to write a scientific manuscript is one of the most important and rewarding scientific training experiences, yet most young scientists only embark on this experience relatively late in graduate school after gathering sufficient data in...

Courses: Bioinformatics Cell Biology Developmental Biology Genetics Microbiology Science Process Skills

geneticsanimaldevelopmentcompetitionbacterial

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5487

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2553

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Exploring the Lytic and Lysogenic Life Cycles of Bacteriophages

The goal of this lesson is to introduce students to the lytic and lysogenic cycles of T4 and lambda bacteriophages, respectively, using student-centered pedagogies. Bacteriophages are viruses that infect bacteria and are either virulent or...

Courses: Microbiology

bacteriophagesLysogenic cycleLysogenyLytic cycle

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271

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Bringing Pasteur Back to Life: Studying the Biochemistry of Yeast Fermentation Through Discussion Groups and an At-Home Lab

This hands-on, student-centered biochemistry lesson introduces beginner biochemistry students to the techniques of effectively reading and discussing primary literature, identifying fundamental biological concepts, and applying that knowledge to...

Courses: Biochemistry and Molecular Biology Microbiology Science Process Skills

primary literatureexperimentationyeastMetabolismFermentationRespirationequilibrium

Teaching Tools and Strategies

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A 360˚ View of COVID-19

In March 2020, institutions underwent a massive transition to distance learning as a result of the COVID-19 pandemic. With so little time to devise new materials to maximize learning in the new virtual environment, instructors devised a variety of...

Courses: Biochemistry and Molecular Biology Bioinformatics Cell Biology Evolution Genetics Immunology Introductory Biology Microbiology Science Process Skills

geneticsImmunologyBiochemistrybioinformaticsmolecular evolutionpublic healthvirusCOVID19

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CRISPR/Cas9 in yeast: a multi-week laboratory exercise for undergraduate students

Providing undergraduate life-science students with a course-based research experience that utilizes cutting-edge technology, is tractable for students, and is manageable as an instructor is a challenge. Here, I describe a multi-week lesson plan...

Courses: Biochemistry and Molecular Biology Bioinformatics Genetics Microbiology Science Process Skills

bioinformaticsPCRphenotypingCRISPR/Cas9gene editingcloningGenotypingRestriction enzyme

Teaching Tools and Strategies

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A Journal Club Project to Promote Interpreting and Presenting Information From the Primary Scientific Literature

Many undergraduate students receive little guidance on how to critically read, interpret data within, or present information from the primary scientific literature before they begin senior independent research experiences or enter professional or...

Courses: Developmental Biology Neurobiology

primary literaturejournal clubScience CommunicationfeedbackPeer reviewgroup workOral presentationProcess skillsPeer evaluationDevelopmental neurobiology

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495

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Does Organelle Shape Matter?: Exploring Patterns in Cell Shape and Structure with High-Throughput (HT) Imaging

Organelle structure has been studied and visualized for decades; however, publicly available databases that use improved high-throughput microscopy of gene-edited cell lines have recently revolutionized the amount and quality of information now...

Courses: Biochemistry and Molecular Biology Bioinformatics Cell Biology Genetics Science Process Skills

modelingcase studymicroscopystructureOrganellesHigh-throughput (HT)Endoplasmic Reticulum (ER)Fluorescent microscopyHuman Cell Biology

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Infectious Chocolate Joy with a Side of Poissonian Statistics: An activity connecting life science students with subtle physics concepts

Introductory physics courses are required for many programs in the life sciences, yet traditional curricula fail to help students meaningfully connect physical concepts with biological systems. In this lesson, we describe an activity taught...

Courses: Bioinformatics Microbiology Science Process Skills

quantitative biologyHIVmultiplicity of infectionPoisson DistributionPhysics for biologists

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Enhancing the Microscopy Skills of Non-Science Majors and Nursing Microbiology Students: Promoting the Practice of Observing Multiple Fields of View Using Blood Smear Slides

Understanding Host-Pathogen Interactions With the Use of Galleria mellonella

Mice, Acorns, and Lyme Disease: a Case Study to Teach the Ecology of Emerging Infectious Diseases.

Small Organisms with Big Consequences: Understanding the Microbial World Around Us

A CURE for Salmonella: A Laboratory Course in Pathogen Microbiology and Genomics

My Fish Tank: An Active Learning Activity for Bacterial Nitrogen Metabolism

Antibiotic Resistance Genes Detection in Environmental Samples

From Dirt to Streptomyces DNA

Follow the Sulfur: Using Yeast Mutants to Study a Metabolic Pathway

The Great Petunia Carnage of 2017: A Clicker Case Study Using Petunias to Describe the Effect of Genetic Modification on the Biochemistry of Flower Color and Phenotype in Plants

You and Your Oral Microflora: Introducing non-biology majors to their “forgotten organ”

Using QIIME to Interpret Environmental Microbial Communities in an Upper Level Metagenomics Course

Manuscript 101: A Data-Driven Writing Exercise for Beginning Scientists

Exploring the Lytic and Lysogenic Life Cycles of Bacteriophages

Bringing Pasteur Back to Life: Studying the Biochemistry of Yeast Fermentation Through Discussion Groups and an At-Home Lab

A 360˚ View of COVID-19

CRISPR/Cas9 in yeast: a multi-week laboratory exercise for undergraduate students

A Journal Club Project to Promote Interpreting and Presenting Information From the Primary Scientific Literature

Does Organelle Shape Matter?: Exploring Patterns in Cell Shape and Structure with High-Throughput (HT) Imaging

Infectious Chocolate Joy with a Side of Poissonian Statistics: An activity connecting life science students with subtle physics concepts

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