Text Search:
Applied Filters
    Lesson
    2644

    views

    183

    downloads

    0

    comments

    Gotcha! Which fly trap is the best? An introduction to experimental data collection and analysis
    Collecting data from experimental observations is an important component of the scientific process; likewise, the analysis of the data is essential to understanding the observed trends and patterns from any experiment. Allowing students to...
    data analysisexperimental designdata collectionfruit fliesfly traps
    Science Behind the Lesson
    1181

    views

    161

    downloads

    0

    comments

    The Science Behind the ACTN3 Polymorphism
    A common polymorphism in the alpha-actinin-3 (ACTN3) gene results in the lack of ACTN3 protein expression in fast twitch muscle fibers in ~16% of the human population (1). This genetic change has been linked with muscle performance in humans (2)...
    protein structure and functionhuman genetic variationskeletal muscle physiology
    Lesson
    1015

    views

    312

    downloads

    0

    comments

    The ACTN3 Polymorphism: Applications in Genetics and Physiology Teaching Laboratories
    Inquiry-based undergraduate laboratories provide the opportunity to engage students in a research experience that improves scientific thinking, but such activities can be difficult to develop and implement due to limited time and resources. We...
    protein structure and functionhuman genetic variationmuscle physiology
    Lesson
    1777

    views

    428

    downloads

    0

    comments

    A Short Laboratory Module to Help Infuse Metacognition during an Introductory Course-based Research Experience
    A core competency identified in Vision and Change for undergraduate biology students is the Ability to Apply the Process of Science. Here, we describe a three-week laboratory module for students in an Introductory Cell and Molecular Biology...
    metacognitiongene expressionScientific ProcessExperimenal DesignHypothesis Generationmodel organisms
    Lesson
    3022

    views

    1084

    downloads

    0

    comments

    CRISPR/Cas9 in yeast: a multi-week laboratory exercise for undergraduate students
    Providing undergraduate life-science students with a course-based research experience that utilizes cutting-edge technology, is tractable for students, and is manageable as an instructor is a challenge. Here, I describe a multi-week lesson plan...
    bioinformaticsPCRphenotypingCRISPR/Cas9gene editingcloningGenotypingRestriction enzyme
    Lesson
    11006

    views

    1665

    downloads

    2

    comments

    A virtual laboratory on cell division using a publicly-available image database
    Cell division is a key concept in cell biology. While there are many popular activities to teach students the stages of mitosis, most make use of simple schematics, cartoons, or textbook diagrams. Others engage students in acting out the stages,...
    image analysismicroscopymitosisCellular Processes
    Lesson
    4627

    views

    864

    downloads

    0

    comments

    Tackling "Big Data" with Biology Undergrads: A Simple RNA-seq Data Analysis Tutorial Using Galaxy
    Analyzing high-throughput DNA sequence data is a fundamental skill in modern biology. However, real and perceived barriers such as massive file sizes, substantial computational requirements, and lack of instructor background knowledge can...
    bioinformaticsDNA sequenceRNAseqgene expression
    Lesson
    5710

    views

    3759

    downloads

    0

    comments

    CURE-all: Large Scale Implementation of Authentic DNA Barcoding Research into First-Year Biology Curriculum
    Growing calls in science education reform have emphasized wide-scale engagement of first-year undergraduate students in authentic research experiences; however, large course enrollments, inadequate student experience, limited resources and...
    phylogeneticsbioinformaticsBiodiversityprocess of sciencetaxonomyPCRDNADNA sequencegel electrophoresis
    Lesson
    912

    views

    273

    downloads

    0

    comments

    Quantifying and Visualizing Campus Tree Phenology
    Large enrollment courses present a challenge for instructors who want to engage students in authentic science practices that fit the recommendations of Vision & Change. Our lesson provides a meaningful science experience for undergraduates in...
    ecologyBiodiversityphenologyplant biology
    Lesson
    1974

    views

    232

    downloads

    1

    comments

    Discovering Prokaryotic Gene Regulation by Building and Investigating a Computational Model of the lac Operon
    The ability to construct and reason through a biological system is an important skill to develop in science education. This level of understanding forces students to recognize the interrelatedness of components within a biological process and...
    prokaryotesgene regulationLac Operoninducible operon
    Lesson
    1825

    views

    623

    downloads

    1

    comments

    Sequence Similarity: An inquiry based and "under the hood" approach for incorporating molecular sequence alignment in introductory undergraduate biology courses
    Introductory bioinformatics exercises often walk students through the use of computational tools, but often provide little understanding of what a computational tool does "under the hood." A solid understanding of how a bioinformatics...
    BLASTmultiple sequence alignmentsequence similarityphylogramZika virusAlgorithmScoring Matrix
    Lesson
    1565

    views

    546

    downloads

    0

    comments

    A Close-Up Look at PCR
    The Polymerase Chain Reaction (PCR) is a fundamental laboratory technique that allows for the amplification of many copies of a desired DNA target sequence. Despite its prevalence, undergraduate students often have poor comprehension about the...
    PCRDNA replication
    Lesson
    3650

    views

    261

    downloads

    0

    comments

    Learning to Pipet Correctly by Pipetting Incorrectly?
    Beginning undergraduate students in biology need basic laboratory, data analysis, and science process skills to pursue more complex questions in course-based undergraduate research experiences (CUREs). To this end, we designed an introductory...
    statisticslaboratorypipetting
    Lesson
    7543

    views

    355

    downloads

    0

    comments

    Investigating Cell Signaling with Gene Expression Datasets
    Modern molecular biology is a data- and computationally-intensive field with few instructional resources for introducing undergraduate students to the requisite skills and techniques for analyzing large data sets. This Lesson helps students: (i)...
    genomicstranscriptionsignaling
    Lesson
    1989

    views

    373

    downloads

    0

    comments

    Dynamic Daphnia: An inquiry-based research experience in ecology that teaches the scientific process to first-year biologists
    This authentic research experience lesson teaches the core concept of systems and the competencies of quantitative reasoning, communication, and the ability to apply science. The research is student driven, the results are unknown, and the...
    statisticsecologyscientific methodexperimental designAbiotic and Biotic FactorsDependent and Independent Variables
    Lesson
    18471

    views

    375

    downloads

    0

    comments

    A flexible, multi-week approach to plant biology - How will plants respond to higher levels of CO2?
    To help introductory biology students understand how plants will respond to higher levels of CO2, we have created a multi-week module consisting of a series of four related laboratory lessons. These lessons allow students to make connections among...
    statisticsplantsphotosynthesiscarbon dioxidecommunicating sciencegroup workResource AllocationRespirationStomata
    Lesson
    2305

    views

    252

    downloads

    0

    comments

    The Leaky Neuron: Understanding synaptic integration using an analogy involving leaky cups
    Students have difficulty understanding synaptic integration in neural circuits, and how spatial and temporal summation combine in a target neuron to reach threshold.  This Lesson uses small cups of water to represent excitatory postsynaptic...

    Courses: NeurobiologyNeurobiology

    neuron physiologyspatial summationsynaptic integrationtemporal summationthreshold
    Lesson
    3321

    views

    361

    downloads

    0

    comments

    Discovering Prokaryotic Gene Regulation with Simulations of the trp Operon
    The trp operon exemplifies important biological concepts, including the central dogma of molecular biology, feedback inhibition, and gene regulation. For this reason, regulation of the trp operon is a common theme in introductory biology,...
    prokaryotesgene regulationattenuationfeedback inhibitionrepressible operontrp operon
    Lesson
    1359

    views

    303

    downloads

    0

    comments

    Understanding Protein Domains: A Modular Approach
    An understanding of protein structure, function, and interaction is central to biochemistry. One angle into this topic is to engage students in considering protein domains as modules that develop form and execute function semi-independently. Here,...
    Protein Structure
    Lesson
    2397

    views

    547

    downloads

    0

    comments

    Linking Genotype to Phenotype: The Effect of a Mutation in Gibberellic Acid Production on Plant Germination
    Basic concepts in genetics and plant development are often taught in lecture courses without a lab component. This approach provides students with the content knowledge, but fails to make connections to research opportunities and real-world...
    geneticsdevelopmentmutationgerminationplantmodel organismGenotype/PhenotypeHormoneSeed