CourseSource: Resources

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The Developmental Origins of Mythology: A Pandemic-Inspired Innovative Developmental Biology Laboratory Exercise

From an experiential, hands-on perspective, the Developmental Biology Laboratory is easily amenable to a wide range of undergraduate-friendly experiments. Thus, pivoting to a virtual laboratory during the COVID-19 pandemic required significant...

Courses: Developmental Biology

gastrulationaxis formationlimb developmentchimeramidline

Lesson

1164

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58

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Defining Life: Exploring Creativity, Scientific Discovery, and Biology Core Concepts in a Disciplinary First-Year Seminar

This unit, Defining Life, engages students in thinking like scientists, applying creativity to science, and learning biology core concepts as they explore the defining characteristics of life. This unit provides an example of a curriculum designed...

Courses: Biochemistry and Molecular Biology Cell Biology Evolution Genetics Introductory Biology Microbiology Science Process Skills

Evolutionbiologycellprocess of science

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2041

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282

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Assessing in vivo Antimicrobial Activity Through the Analysis of Galleria mellonella Kaplan-Meier Plots

Antimicrobials and their use in the treatment of bacterial infections are a fundamental lesson in all microbiology courses. Typically, cultivation-based methods are used to teach students about antimicrobial testing. A complementary approach...

Courses: Microbiology

Antimicrobial TestingAntimicrobialsInvertebrate animal models

Teaching Tools and Strategies

2521

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373

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A Remote-Learning Framework for Student Research Projects: Using Datasets to Teach Experimental Design, Data Analysis and Science Communication

Remote learning often requires an alternative to hands-on, student-designed research projects. To this end, we created a package of scaffolded assignments to support introductory students through the research process using datasets from past...

Courses: Introductory Biology Science Process Skills

population growthphysiologyecotoxicologyphotosynthesis

Lesson

6099

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3893

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CURE-all: Large Scale Implementation of Authentic DNA Barcoding Research into First-Year Biology Curriculum

Growing calls in science education reform have emphasized wide-scale engagement of first-year undergraduate students in authentic research experiences; however, large course enrollments, inadequate student experience, limited resources and...

Courses: Biochemistry and Molecular Biology Bioinformatics Ecology Ecology Evolution Genetics Introductory Biology Science Process Skills

phylogeneticsbioinformaticsBiodiversityprocess of sciencetaxonomyPCRDNADNA sequencegel electrophoresis

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1539

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338

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Investigating Gene Expression and Cell Specialization in Axolotl Embryos

The process of cell specialization is critical to the formation and function of tissues in animals and plants. Although gene expression, including the regulation of transcription, is taught in most introductory cell biology courses, the...

Courses: Biochemistry and Molecular Biology Cell Biology Developmental Biology Science Process Skills

developmenttranscriptiongene expressionmodel organismembryo

Lesson

1915

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274

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A CURE-based approach to teaching genomics using mitochondrial genomes

There is an abundance (currently over 1016 DNA bases) of publicly available genetic sequence data and a dearth of trained genomicists to process and interpret it, necessitating more trained bioinformaticians with biological expertise. For...

Courses: Bioinformatics Genetics

proteinsMitochondrial GenomesNuclear GenomesrRNAtRNA

Lesson

2809

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224

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A Case Study for Teaching Toxicology: Using Whales as an Indicator for Environmental Health

One of the challenges of teaching scientific courses is helping students understand research methods, biological models, and data analysis, which can be especially difficult in classes without a laboratory component. Within the field of...

Courses: Science Process Skills Toxicology

absorptionone environmental health hypothesismetals

Lesson

6009

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1220

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A CURE for Salmonella: A Laboratory Course in Pathogen Microbiology and Genomics

Rapid advances in genomics and bioinformatics, the vast amount of data generated by next-generation sequencing, and the penetration of the ‘-omics’ into many areas of biology have created a need for students with hands-on experience with...

Courses: Biochemistry and Molecular Biology Bioinformatics Ecology Ecology Microbiology

epidemiologyresearchbioinformaticsgenomicspublic healthAntibiotic Resistant BacteriaSalmonellaDNA sequencingpathogenic bacteria

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2827

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337

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0

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Bacteria to Brains in Backyard Coyotes: An Interdisciplinary Pedagogical Case Study

Our interdisciplinary pedagogical case study explores the differences between rural and urban coyotes at the levels of organismal and community ecology. The focus is on how coyotes’ gut microbiomes could affect their behavior via...

Courses: Cell Biology Ecology Ecology Evolution Immunology Introductory Biology Microbiology

dietanimal behaviorimmune systemmicrobiomeNervous systemgut-brain axisImmunoReachdysbiosisCoyoteCytokines

Lesson

3349

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262

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Garden Variety Mutations: Using Primary Data to Understand the Central Dogma in Large-Lecture Introductory Biology

The ability to interpret and create an argument from data is a crucial skill for budding scientists, yet one that is seldom practiced in introductory courses. During this argumentation module, students in a large lecture class will work in groups...

Courses: Biochemistry and Molecular Biology Genetics Introductory Biology

mutationtranscriptiongene expressioncentral dogmatranslationgel electrophoresisGenotype/Phenotype

Lesson

2174

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421

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Dynamic Daphnia: An inquiry-based research experience in ecology that teaches the scientific process to first-year biologists

This authentic research experience lesson teaches the core concept of systems and the competencies of quantitative reasoning, communication, and the ability to apply science. The research is student driven, the results are unknown, and the...

Courses: Ecology Ecology Introductory Biology Science Process Skills

statisticsecologyscientific methodexperimental designAbiotic and Biotic FactorsDependent and Independent Variables

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1608

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177

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Nanoparticles and Shrimp: An Interdisciplinary Lab Series in Chemistry and Biology for Undergraduate Engineering Students

The parallels between engineering and science are vast, as both disciplines apply theory and inquiry to solve complex problems. In order to prepare students for interdisciplinary careers in STEM, we have developed a lab project in which...

Courses: Cell Biology Ecology Ecology Science Process Skills

microscopychemistry applications in biologytoxicity

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18695

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400

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0

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A flexible, multi-week approach to plant biology - How will plants respond to higher levels of CO₂?

To help introductory biology students understand how plants will respond to higher levels of CO2, we have created a multi-week module consisting of a series of four related laboratory lessons. These lessons allow students to make connections among...

Courses: Introductory Biology Plant Biology

statisticsplantsphotosynthesiscarbon dioxidecommunicating sciencegroup workResource AllocationRespirationStomata

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Teaching RNAseq at Undergraduate Institutions: A tutorial and R package from the Genome Consortium for Active Teaching

Next-generation sequencing is radically changing the study of biology, but there are currently few resources aimed at teaching the required laboratory and data-analysis skills to undergraduate students. This gap is especially true at primarily...

Courses: Bioinformatics Introductory Biology

statisticsbioinformaticsRNAseqgene expressioncomputer programming

Lesson

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914

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Coevolution or not? Crossbills, squirrels and pinecones

This case reinforces the concept of coevolution as a reciprocal change in genetic structure between or among two or more populations, by having students analyze and interpret data, build a descriptive model of the system, and use data to make...

Courses: Ecology Ecology Evolution Introductory Biology Science Process Skills

fitnessCoevolutionCo-adaptation

Lesson

1978

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Exploration of the Human Genome by Investigation of Personalized SNPs

Students often shy away from tedious bioinformatics approaches to exploring their genomes. However, in our expanding digital world these skills are some of the most relevant and valuable. To increase students' interest in their own genomes, I...

Courses: Bioinformatics Genetics Science Process Skills

UCSC genome browsersingle nucleotide polymorphismGenome wide association studiesGenomic organization

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Moths and Frogs and E. coli, Oh My!: Agent-based Modeling of Evolutionary Systems

In evolution classrooms, introducing and reinforcing the idea of genetic drift and random selection can be challenging, as can be reinforcing appropriate mental models of evolution. Agent-based models offer students the opportunity to conduct a...

Courses: Bioinformatics Ecology Ecology Evolution Science Process Skills

modelingEvolutionecologyagent-based modelingGenetic Driftenvironmental scienceNatural Selectioncompetitive coevolutionsimulation modelingevolutionary reasoning

Lesson

3263

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266

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Application of a Bacterial Experimental Evolution System to Visualize and Teach Evolution in Action: A Course-Based Undergraduate Research Experience

Concepts of evolution are typically taught through examples of extremely long timescales, which do not always resonate broadly. Here, we describe a course-based undergraduate research experience tailored for junior and senior undergraduate biology...

Courses: Biochemistry and Molecular Biology Bioinformatics Cell Biology Evolution Genetics Microbiology

EvolutionmutationcompetitionNatural Selectionregulationstructure and functionreproductive fitnessgenotype to phenotypehomologs

Lesson

1250

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346

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A first lesson in mathematical modeling for biologists: Rocs

Using a fictitious population of Rocs, a mythical species of giant raptor, students accomplish two broad objectives: 1) they undertake the process of building a first mathematical model of a population, and 2) they begin to develop their...

Courses: Ecology Ecology Introductory Biology Science Process Skills

population ecologypopulation modelingdiscrete generationpopulation management

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The Developmental Origins of Mythology: A Pandemic-Inspired Innovative Developmental Biology Laboratory Exercise

Defining Life: Exploring Creativity, Scientific Discovery, and Biology Core Concepts in a Disciplinary First-Year Seminar

Assessing in vivo Antimicrobial Activity Through the Analysis of Galleria mellonella Kaplan-Meier Plots

A Remote-Learning Framework for Student Research Projects: Using Datasets to Teach Experimental Design, Data Analysis and Science Communication

CURE-all: Large Scale Implementation of Authentic DNA Barcoding Research into First-Year Biology Curriculum

Investigating Gene Expression and Cell Specialization in Axolotl Embryos

A CURE-based approach to teaching genomics using mitochondrial genomes

A Case Study for Teaching Toxicology: Using Whales as an Indicator for Environmental Health

A CURE for Salmonella: A Laboratory Course in Pathogen Microbiology and Genomics

Bacteria to Brains in Backyard Coyotes: An Interdisciplinary Pedagogical Case Study

Garden Variety Mutations: Using Primary Data to Understand the Central Dogma in Large-Lecture Introductory Biology

Dynamic Daphnia: An inquiry-based research experience in ecology that teaches the scientific process to first-year biologists

Nanoparticles and Shrimp: An Interdisciplinary Lab Series in Chemistry and Biology for Undergraduate Engineering Students

A flexible, multi-week approach to plant biology - How will plants respond to higher levels of CO₂?

Teaching RNAseq at Undergraduate Institutions: A tutorial and R package from the Genome Consortium for Active Teaching

Coevolution or not? Crossbills, squirrels and pinecones

Exploration of the Human Genome by Investigation of Personalized SNPs

Moths and Frogs and E. coli, Oh My!: Agent-based Modeling of Evolutionary Systems

Application of a Bacterial Experimental Evolution System to Visualize and Teach Evolution in Action: A Course-Based Undergraduate Research Experience

A first lesson in mathematical modeling for biologists: Rocs

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