CourseSource: Resources

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The Impact of Diet and Antibiotics on the Gut Microbiome: Distance Education Variant

The goal of this article is to describe a variation of an active learning exercise that was previously published by the same author under a similar title. The variation describes modifications instructors can use to make the exercise suitable for...

Courses: Biochemistry and Molecular Biology Microbiology

microbiomenutritionbacterial metabolitesgut bacteriahost response

Lesson

3763

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285

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Fragile States: A Case Study Exploring Genetics, Molecular Biology, and Biochemistry Through the Lens of Fragile X Syndrome

This case aims to strengthen students’ understanding of molecular biology concepts through study of Fragile X Syndrome (FXS). Students begin by learning the cause and phenotypes of FXS and related conditions. Students then apply genetics...

Courses: Biochemistry and Molecular Biology Genetics

gene regulationtranscriptiontranslationFragile X syndrometriplet repeat expansionsex linkagemetabolic pathway

Lesson

2324

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472

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From Dirt to Streptomyces DNA

The purpose of this semester-long Lesson is to give students an authentic, course-based undergraduate research experience during which they learn basic and advanced microbiological and molecular biology techniques. This project begins with the...

Courses: Microbiology

MetabolismAntibiotic productionrRNA genesSecondary metabolitesStreptomyces

Lesson

4304

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1461

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Evaluating the Quick Fix: Weight Loss Drugs and Cellular Respiration

One key to student success in introductory and cell biology courses is a foundational knowledge of cellular respiration. This is a content area in which students often harbor misconceptions that make cellular respiration particularly challenging...

Courses: Biochemistry and Molecular Biology Cell Biology Introductory Biology

data analysisCellular RespirationElectron Transport ChainEnergy transformationsMitochondriaOxidative phosphorylationWeight loss drugs24-dinitrophenol (DNP)

Lesson

18767

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406

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A flexible, multi-week approach to plant biology - How will plants respond to higher levels of CO₂?

To help introductory biology students understand how plants will respond to higher levels of CO2, we have created a multi-week module consisting of a series of four related laboratory lessons. These lessons allow students to make connections among...

Courses: Introductory Biology Plant Biology

statisticsplantsphotosynthesiscarbon dioxidecommunicating sciencegroup workResource AllocationRespirationStomata

Lesson

981

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122

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My Fish Tank: An Active Learning Activity for Bacterial Nitrogen Metabolism

This active learning activity introduces students to the second part of the nitrogen cycle, nitrification. In terrestrial and aquatic environments, bacteria from the Nitrosomonas and Nitrobacter genera oxidize ammonia first to nitrite (via a...

Courses: Biochemistry and Molecular Biology Ecology Ecology Microbiology

nitrogen cyclenitrificationnitrifying bacteria

Lesson

3039

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207

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The Three Sisters of Agriculture: An Active Learning Activity on Symbiotic Nitrogen Fixation

This active learning exercise introduces students to the plant microbiome and the contributions that bacteria make to plant growth and food production. The Three Sisters are an ancient indigenous practice in which three plant crops and the...

Courses: Microbiology

SymbiosisPlant microbiomeNitrogen fixationNutritional content of foodElectron flowSociety impact of microorganisms

Lesson

4351

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84

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The Great Petunia Carnage of 2017: A Clicker Case Study Using Petunias to Describe the Effect of Genetic Modification on the Biochemistry of Flower Color and Phenotype in Plants

In this single class period case study, students examine the difference between genotype and phenotype by studying the mechanisms by which commercially available petunias have been bred to have different phenotypes (flower colors). Students review...

Courses: Genetics Introductory Biology Plant Biology

case studyGenetic ModificationsBiochemistry of Flower ColorGMO regulationsGenotype-Phenotype Connections

Lesson

2649

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263

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Pick Your Poison: A Semester-Long Case Study for Undergraduate Toxicology

The ability to collate information from diverse scientific resources and effectively employ scientific writing is an essential skill for scientists. This lesson describes a semester-long project entitled “Pick Your Poison,” which is...

Courses: Toxicology

risk assessmenttoxicologyPharmacologyregulationsdose responseADME

Lesson

4487

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718

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Problem-Based Learning for Physiology: Synthesizing the Cardiovascular System, Respiration, Macronutrient Metabolism, and Renal Function

Problem Based Learning (PBL) is a valuable tool for helping students overcome reliance on memorization by scaffolding opportunities for them to practice the competency of “systems thinking,” which is the ability to understand...

Courses: Anatomy-Physiology

MetabolismObesityblood pressurecardiac functioncardiovascularmetabolic syndromerenalRespirationrespiratory system

Science Behind the Lesson

1485

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202

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The Science Behind the ACTN3 Polymorphism

A common polymorphism in the alpha-actinin-3 (ACTN3) gene results in the lack of ACTN3 protein expression in fast twitch muscle fibers in ~16% of the human population (1). This genetic change has been linked with muscle performance in humans (2)...

Courses: Anatomy-Physiology Genetics

protein structure and functionhuman genetic variationskeletal muscle physiology

Lesson

435

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66

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The Science and Ethics of Gene Drives: An Active Learning Lesson in Genetics

Coursework connecting biology to socially relevant issues and ethical questions can help students think about biology in interdisciplinary terms. Gene drives represent one topic involving both advanced biology concepts and societally relevant...

Courses: Genetics

bioethicsCRISPR/Cas9Genetic modificationGene drives

Lesson

3689

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271

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Bringing Pasteur Back to Life: Studying the Biochemistry of Yeast Fermentation Through Discussion Groups and an At-Home Lab

This hands-on, student-centered biochemistry lesson introduces beginner biochemistry students to the techniques of effectively reading and discussing primary literature, identifying fundamental biological concepts, and applying that knowledge to...

Courses: Biochemistry and Molecular Biology Microbiology Science Process Skills

primary literatureexperimentationyeastMetabolismFermentationRespirationequilibrium

Lesson

2995

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346

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0

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A Muscular Dystrophy Case Study Illustrating the Phenotypic Effects of Mutation

Mutations in genes can lead to a variety of phenotypes, including various human diseases. Students often understand that a particular mutation in a single gene causes a disease phenotype, but it is more challenging to illustrate complex genetic...

Courses: Developmental Biology Genetics

mutationProtein Structureethicscentral dogmahuman disease

Lesson

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275

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Application of a Bacterial Experimental Evolution System to Visualize and Teach Evolution in Action: A Course-Based Undergraduate Research Experience

Concepts of evolution are typically taught through examples of extremely long timescales, which do not always resonate broadly. Here, we describe a course-based undergraduate research experience tailored for junior and senior undergraduate biology...

Courses: Biochemistry and Molecular Biology Bioinformatics Cell Biology Evolution Genetics Microbiology

EvolutionmutationcompetitionNatural Selectionregulationstructure and functionreproductive fitnessgenotype to phenotypehomologs

Lesson

4810

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770

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Teaching Cancer Biology Through a Lens of Social Justice

The biology classroom is not separate from the greater context of society; social issues can and should be presented in connection with the content. Here we present an example of antiracist teaching using the molecular/cellular biology of cancer...

Courses: Cell Biology

assessmentcancersocial justicePOGILAlignmentPublic ExamPublic

Lesson

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Bacteria to Brains in Backyard Coyotes: An Interdisciplinary Pedagogical Case Study

Our interdisciplinary pedagogical case study explores the differences between rural and urban coyotes at the levels of organismal and community ecology. The focus is on how coyotes’ gut microbiomes could affect their behavior via...

Courses: Cell Biology Ecology Ecology Evolution Immunology Introductory Biology Microbiology

dietanimal behaviorimmune systemmicrobiomeNervous systemgut-brain axisImmunoReachdysbiosisCoyoteCytokines

Lesson

1686

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394

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Taking the Hassle out of Hasselbalch

Mention pH in a classroom and you can almost see the inner yawn on the faces of your students. The definition may even roll easily from their lips. However, despite multiple exposures to the relationship of pH and pKa throughout a typical...

Courses: Biochemistry and Molecular Biology Science Process Skills

pHdrug uptakeHenderson-Hasslbalch equationmedical applicationspKa

Lesson

959

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230

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Exploring the Broader Impacts of Science and Society in an Active Learning Environment

Science and society have always been intertwined. Today, scientists are increasingly encouraged to interact with the public by conducting transparent and participatory engaged scholarship, as opposed to the prevailing one-way transfer of...

Courses: Introductory Biology Professional Development and Career Planning Science Process Skills

active learningsocietyScience CommunicationscienceBroader impactsPublic engagement

Lesson

3159

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458

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Small Organisms with Big Consequences: Understanding the Microbial World Around Us

Creating a hands-on lab that conveys important information while simultaneously allowing for student autonomy can be difficult. This is particularly true for the field of microbiology, in which labs often rely on “recipe-style”...

Courses: Introductory Biology Microbiology Science Process Skills

disease transmissionmicrobiologymicrobiomeliterature reviewPeer reviewPathogensHealth and WellnessThe Scientific Method

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The Impact of Diet and Antibiotics on the Gut Microbiome: Distance Education Variant

Fragile States: A Case Study Exploring Genetics, Molecular Biology, and Biochemistry Through the Lens of Fragile X Syndrome

From Dirt to Streptomyces DNA

Evaluating the Quick Fix: Weight Loss Drugs and Cellular Respiration

A flexible, multi-week approach to plant biology - How will plants respond to higher levels of CO₂?

My Fish Tank: An Active Learning Activity for Bacterial Nitrogen Metabolism

The Three Sisters of Agriculture: An Active Learning Activity on Symbiotic Nitrogen Fixation

The Great Petunia Carnage of 2017: A Clicker Case Study Using Petunias to Describe the Effect of Genetic Modification on the Biochemistry of Flower Color and Phenotype in Plants

Pick Your Poison: A Semester-Long Case Study for Undergraduate Toxicology

Problem-Based Learning for Physiology: Synthesizing the Cardiovascular System, Respiration, Macronutrient Metabolism, and Renal Function

The Science Behind the ACTN3 Polymorphism

The Science and Ethics of Gene Drives: An Active Learning Lesson in Genetics

Bringing Pasteur Back to Life: Studying the Biochemistry of Yeast Fermentation Through Discussion Groups and an At-Home Lab

A Muscular Dystrophy Case Study Illustrating the Phenotypic Effects of Mutation

Application of a Bacterial Experimental Evolution System to Visualize and Teach Evolution in Action: A Course-Based Undergraduate Research Experience

Teaching Cancer Biology Through a Lens of Social Justice

Bacteria to Brains in Backyard Coyotes: An Interdisciplinary Pedagogical Case Study

Taking the Hassle out of Hasselbalch

Exploring the Broader Impacts of Science and Society in an Active Learning Environment

Small Organisms with Big Consequences: Understanding the Microbial World Around Us

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