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Interactive Video Vignettes (IVVs) to Help Students Learn Genetics Concepts

Many video resources exist to teach Mendelian genetics, but most consist of passive delivery of information rather than active construction of knowledge by users. We have created two interactive video vignettes (IVVs) that can be used together or...

Courses: Genetics Introductory Biology Science Process Skills

genotypephenotypeallelespedigreedominanceHardy-Weinberg equilibriumInheritance

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4484

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449

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Teaching Advanced Concepts in Regulation of the Lac Operon With Modeling and Simulation

Success in biochemistry and other life science courses requires that students understand important biological concepts. One of these concepts is how gene regulation ensures that homeostasis is maintained in an organism. The lac operon is a...

Courses: Biochemistry and Molecular Biology

gene regulationinducible operonProkaryotic cellPhosphoenolpyruvate transferase system (PTS)

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Teaching Cancer Biology Through a Lens of Social Justice

The biology classroom is not separate from the greater context of society; social issues can and should be presented in connection with the content. Here we present an example of antiracist teaching using the molecular/cellular biology of cancer...

Courses: Cell Biology

assessmentcancersocial justicePOGILAlignmentPublic ExamPublic

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Metastatic Mastery: A Case and Game-Based Approach to Learning About Cancer Mechanisms

Mechanisms that contribute to the development of cancer are numerous and complicated, though most can be traced to a set of mutations in cell cycle regulatory genes that throw the process of cell division off balance. Communication of these...

Courses: Biochemistry and Molecular Biology Genetics Introductory Biology

mutationcancertranscriptioncell cycletranslationOncogenesTumor-suppressorp53Transcription factor

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3355

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618

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Predicting and classifying effects of insertion and deletion mutations on protein coding regions

Mutations in genes can affect the encoded proteins in multiple ways, and some of these effects are counterintuitive. As for any other knowledge, students must create their own deep understanding of the Central Dogma. Students may not develop this...

Courses: Bioinformatics Genetics Science Process Skills

mutationcentral dogmatranslationframeshift

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503

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Translating Co-Translational Translocation

Understanding the process of proteins targeting to specific locations within a cell is a fundamental part of cell biology. Synthesis of proteins by co-translational translocation, which also determines the resulting protein topology, is a complex...

Courses: Cell Biology

Topologyco-translational translocationendoplasmic reticulumprotease protection assaysecretory proteinssignal sequencetransmembrane proteins

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3161

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899

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Fruit Fly Genetics in a Day: A Guided Exploration to Help Many Large Sections of Beginning Students Uncover the Secrets of Sex-linked Inheritance

Moving beyond the basic concepts of autosomal Mendelian inheritance to sex-linkage can be difficult for introductory biology students. Although crosses with Drosophila fruit flies have long been a mainstay of genetics units that teach these...

Courses: Genetics

Mendelian Geneticsfruit fly biologysex-linked inheritance

Lesson

1261

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185

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Simulating Cortical Rotation, Axis Induction, and Experimental Embryology in Amphibian Embryos Using Clay Models

The study of development requires learners to understand spatially complex concepts like embryo anatomy. Embryo anatomy is dynamic over time, and it is often manipulated by researchers in experiments that are fundamental to the field. This spatial...

Courses: Developmental Biology

developmentXenopusfertilizationEmbryologyinductionSymmetry breakingOrganizerCortical rotationPatterning

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389

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61

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Environmental Injustice: When the Grass is Greener on the Other Side

Environmental pollution is a global threat that is especially prevalent in heavily industrialized and urbanized areas. Pollution can be found in many forms, such as natural and synthetic pollutants from natural and anthropogenic processes. These...

Courses: Ecology Ecology Introductory Biology Science Process Skills Toxicology

human healthenvironmental injusticeEnvironmental PollutionSystemic BiasesIdeological AwarenessUrban Ecology and Development

Essay

836

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126

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Implementing active learning approaches into an upper-division biology course

In this essay, we present our strategy for implementing active learning strategies into an upper division course on Human Genetics. Our principal goal was to shift from a traditional didactic course design, to one that more clearly placed the...

Courses: Genetics Introductory Biology

human biologyPedigree analysisRare genetic diseases

Teaching Tools and Strategies

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307

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Sanger Sequencing by Hand: Using Paper Clips to Demonstrate Chain Termination

Sanger sequencing is commonly taught with a hands-on approach. Sanger sequencing involves chain termination by dideoxynucleotides, because they are missing the oxygen on the 3’ carbon atom, which is required for the addition of subsequent...

Courses: Genetics

nucleotidessequencingDNAgel electrophoresisChain Termination

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453

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Moths and Frogs and E. coli, Oh My!: Agent-based Modeling of Evolutionary Systems

In evolution classrooms, introducing and reinforcing the idea of genetic drift and random selection can be challenging, as can be reinforcing appropriate mental models of evolution. Agent-based models offer students the opportunity to conduct a...

Courses: Bioinformatics Ecology Ecology Evolution Science Process Skills

modelingEvolutionecologyagent-based modelingGenetic Driftenvironmental scienceNatural Selectioncompetitive coevolutionsimulation modelingevolutionary reasoning

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307

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Learning Quantitative Genetics: Investigation of Genetic Control for Cold Stress Response in Plants

Course-embedded undergraduate research experiences (CUREs) for students have been shown to increase students’ understanding of the process of science, affirm their scientific identity, and improve retention in STEM fields. Despite many CUREs...

Courses: Genetics

data analysisrecombinationplantsquantitative geneticsabiotic stress responsegenetic control of complex traitsinheritance of complex traits

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Role of Crop Genetic Diversity on Pathogen Impact: The Tale of Two Pathogens

Introductory genetics courses are part of the core curriculum in many different fields, including plant breeding, animal science, biology, microbiology, and natural resource management. Concepts involving genes, inheritance, evolution, and genome...

Courses: Introductory Biology Plant Biology Science Process Skills

plant pathologygenetic diversityDisease TriangleModes of Reproduction

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Differential Gene Expression during Xenopus laevis Development

In Developmental Biology classes, students are challenged with understanding how differential gene expression guides embryonic development. It can be difficult for students to realize that genes need to be turned on or off at the right time and...

Courses: Developmental Biology

gene expressionXenopusearly developmentembryofertilizationin situ hybridization

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Population Ecology of the Northern Spotted Owl

The mathematical modeling of populations utilizing field-collected demographic data is an important component of lab curricula in a variety of undergraduate biology lab courses. During the global pandemic brought about by the SARS-CoV-2 virus in...

Courses: Ecology Ecology Introductory Biology

demographyCommunity Ecologypopulation ecologyconservation biologylife tables

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Tying it All Together: An Activity to Help Students Connect Course Experiences to Posted Learning Outcomes

Instructors of undergraduate courses in Biology and other Science, Technology, Engineering, and Mathematics (STEM) disciplines face an ongoing challenge to foster higher-order thinking and learning skills while also developing a sound conceptual...

Courses: Anatomy-Physiology Bioinformatics Cell Biology Developmental Biology Ecology Ecology Genetics Introductory Biology Microbiology Neurobiology Plant Biology Science Process Skills

metacognitionreflectiongoalsOutcomes

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Air Quality Data Mining: Mining the US EPA AirData website for student-led evaluation of air quality issues

Air pollution directly affects human health endpoints including growth, respiratory processes, cardiovascular health, fertility, pregnancy outcomes, and cancer. Therefore, the distribution of air pollution is a topic that is relevant to all, and...

Courses: Ecology Ecology Introductory Biology Science Process Skills

data miningenvironmental justiceair qualityairpollutionspatial reasoning

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3193

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409

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Honoring the Complexity of Genetics: Exploring the Role of Genes and the Environment Using Real World Examples

Historically, undergraduate genetics courses have disproportionately focused on the impact of genes on phenotypes, rather than multifactorial concepts which consider how a combination of genes, the environment, and gene-by-environment interactions...

Courses: Evolution Genetics Introductory Biology

genesenvironmentMendelQuantitative traitsMultifactorialGene by environment interactions

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Using Pathway Maps to Link Concepts, Peer Review, Primary Literature Searches and Data Assessment in Large Enrollment Classes: An example from teaching ecosystem ecology

As with many other complex topics, teaching ecosystem ecology can be particularly difficult in terms of helping students understand the relationships between the various component parts. We addressed this challenge in a general ecology course by...

Courses: Ecology Ecology Introductory Biology Science Process Skills

energyecosystemNutrientsPathway

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Interactive Video Vignettes (IVVs) to Help Students Learn Genetics Concepts

Teaching Advanced Concepts in Regulation of the Lac Operon With Modeling and Simulation

Teaching Cancer Biology Through a Lens of Social Justice

Metastatic Mastery: A Case and Game-Based Approach to Learning About Cancer Mechanisms

Predicting and classifying effects of insertion and deletion mutations on protein coding regions

Translating Co-Translational Translocation

Fruit Fly Genetics in a Day: A Guided Exploration to Help Many Large Sections of Beginning Students Uncover the Secrets of Sex-linked Inheritance

Simulating Cortical Rotation, Axis Induction, and Experimental Embryology in Amphibian Embryos Using Clay Models

Environmental Injustice: When the Grass is Greener on the Other Side

Implementing active learning approaches into an upper-division biology course

Sanger Sequencing by Hand: Using Paper Clips to Demonstrate Chain Termination

Moths and Frogs and E. coli, Oh My!: Agent-based Modeling of Evolutionary Systems

Learning Quantitative Genetics: Investigation of Genetic Control for Cold Stress Response in Plants

Role of Crop Genetic Diversity on Pathogen Impact: The Tale of Two Pathogens

Differential Gene Expression during Xenopus laevis Development

Population Ecology of the Northern Spotted Owl

Tying it All Together: An Activity to Help Students Connect Course Experiences to Posted Learning Outcomes

Air Quality Data Mining: Mining the US EPA AirData website for student-led evaluation of air quality issues

Honoring the Complexity of Genetics: Exploring the Role of Genes and the Environment Using Real World Examples

Using Pathway Maps to Link Concepts, Peer Review, Primary Literature Searches and Data Assessment in Large Enrollment Classes: An example from teaching ecosystem ecology

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