CourseSource: Resources

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My Dog IS My Homework: Exploring Canine Genetics to Understand Genotype-Phenotype Relationships

To facilitate understanding of the fundamental genetic concept of the genotype-phenotype relationship in our introductory biology students, we designed an engaging multi-week series of related lessons about canine genetics in which students...

Courses: Bioinformatics Genetics Introductory Biology Science Process Skills

gel electrophoresissequence analysiscanine geneticsdeoxyribonucleic acid (DNA)dog coat morphologygenotype and phenotypemutationsPolymerase chain reaction (PCR)single nucleotide polymorphism (SNP)

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4395

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1262

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What is Speciation, How Does It Occur, and Why Is It Important for Conservation?

Speciation provides a framework for classifying biodiversity on Earth and is a central concept in evolutionary biology. To help undergraduate students learn about speciation, we designed a student-centered lesson that uses active-learning...

Courses: Ecology Ecology Genetics Introductory Biology Science Process Skills

EvolutionconservationGenetic DriftSpeciationNatural SelectionBiological species conceptgene flowMorphological species conceptPhylogenetic species concept

Lesson

2369

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287

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You and Your Oral Microflora: Introducing non-biology majors to their “forgotten organ”

With limited time available for laboratory activities, introductory science courses for non-science majors typically use the laboratory period to reinforce material that was previously presented during lecture. This practice was true of a human...

Courses: Genetics Introductory Biology Microbiology Science Process Skills

bacteriamicrobiomeBLASTmicrobesDNA replicationPolymerase chain reaction (PCR)

Lesson

2652

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576

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Linking Genotype to Phenotype: The Effect of a Mutation in Gibberellic Acid Production on Plant Germination

Basic concepts in genetics and plant development are often taught in lecture courses without a lab component. This approach provides students with the content knowledge, but fails to make connections to research opportunities and real-world...

Courses: Cell Biology Developmental Biology Genetics Introductory Biology Plant Biology

geneticsdevelopmentmutationgerminationplantmodel organismGenotype/PhenotypeHormoneSeed

Lesson

4928

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498

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Does Organelle Shape Matter?: Exploring Patterns in Cell Shape and Structure with High-Throughput (HT) Imaging

Organelle structure has been studied and visualized for decades; however, publicly available databases that use improved high-throughput microscopy of gene-edited cell lines have recently revolutionized the amount and quality of information now...

Courses: Biochemistry and Molecular Biology Bioinformatics Cell Biology Genetics Science Process Skills

modelingcase studymicroscopystructureOrganellesHigh-throughput (HT)Endoplasmic Reticulum (ER)Fluorescent microscopyHuman Cell Biology

Lesson

1608

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345

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Investigating Gene Expression and Cell Specialization in Axolotl Embryos

The process of cell specialization is critical to the formation and function of tissues in animals and plants. Although gene expression, including the regulation of transcription, is taught in most introductory cell biology courses, the...

Courses: Biochemistry and Molecular Biology Cell Biology Developmental Biology Science Process Skills

developmenttranscriptiongene expressionmodel organismembryo

Teaching Tools and Strategies

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327

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SCIENCE/Fiction: Modular Template for Class Design

We present a modular scaffold for designing an introductory seminar using speculative fiction and science papers to welcome university undergraduates to the biology major. A list of twelve possible topics is included, such as Memory, Parasites,...

Courses: Anatomy-Physiology Biochemistry and Molecular Biology Cell Biology Evolution Genetics Introductory Biology Neurobiology

geneticscell biologyneurosciencesystems biologyScience Fiction

Essay

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An Active Textbook Converts "Vision and Tweak" to Vision and Change

Multiple reports over more than a century have documented the problems with the way introductory biology has been taught in most colleges and universities. An influential recent report, Vision and Change in Undergraduate Biology Education, has...

Courses: Introductory Biology

Vision and Changeactive learningintroductory biologyFlipped classroomUndergraduatecore competenciescore conceptsactive textbookcurriculum reform

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1204

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141

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Understanding the Importance of Microtubules in Normal Cell Division: Chemotherapy Connection

In introductory courses, students learn about microtubules as important structures but may not engage in a hands-on experience to localize microtubules themselves or to learn about their connection to cancer treatment. In this lesson, students...

Courses: Biochemistry and Molecular Biology Cell Biology Genetics

cancerCell DivisionimmunofluorescenceMicrotubulesAntibodies

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3193

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409

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Honoring the Complexity of Genetics: Exploring the Role of Genes and the Environment Using Real World Examples

Historically, undergraduate genetics courses have disproportionately focused on the impact of genes on phenotypes, rather than multifactorial concepts which consider how a combination of genes, the environment, and gene-by-environment interactions...

Courses: Evolution Genetics Introductory Biology

genesenvironmentMendelQuantitative traitsMultifactorialGene by environment interactions

Lesson

1248

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377

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The ACTN3 Polymorphism: Applications in Genetics and Physiology Teaching Laboratories

Inquiry-based undergraduate laboratories provide the opportunity to engage students in a research experience that improves scientific thinking, but such activities can be difficult to develop and implement due to limited time and resources. We...

Courses: Anatomy-Physiology Genetics

protein structure and functionhuman genetic variationmuscle physiology

Lesson

456

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68

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The Science and Ethics of Gene Drives: An Active Learning Lesson in Genetics

Coursework connecting biology to socially relevant issues and ethical questions can help students think about biology in interdisciplinary terms. Gene drives represent one topic involving both advanced biology concepts and societally relevant...

Courses: Genetics

bioethicsCRISPR/Cas9Genetic modificationGene drives

Teaching Tools and Strategies

774

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67

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A Journal Club Project to Promote Interpreting and Presenting Information From the Primary Scientific Literature

Many undergraduate students receive little guidance on how to critically read, interpret data within, or present information from the primary scientific literature before they begin senior independent research experiences or enter professional or...

Courses: Developmental Biology Neurobiology

primary literaturejournal clubScience CommunicationfeedbackPeer reviewgroup workOral presentationProcess skillsPeer evaluationDevelopmental neurobiology

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317

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Differential Gene Expression during Xenopus laevis Development

In Developmental Biology classes, students are challenged with understanding how differential gene expression guides embryonic development. It can be difficult for students to realize that genes need to be turned on or off at the right time and...

Courses: Developmental Biology

gene expressionXenopusearly developmentembryofertilizationin situ hybridization

Lesson

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168

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A Rapid Genetic Screen Using Wisconsin Fast Plants^®: A Hands-On Approach to Inheritance of de novo Mutations

Some concepts in genetics, such as genetic screens, are complex for students to visualize in a classroom and can be cumbersome to undertake in the laboratory. Typically, very large populations are needed, which can be addressed by using...

Courses: Genetics Plant Biology

mutationInheritancegermlinesomaplant lifecycle

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My Dog IS My Homework: Exploring Canine Genetics to Understand Genotype-Phenotype Relationships

What is Speciation, How Does It Occur, and Why Is It Important for Conservation?

You and Your Oral Microflora: Introducing non-biology majors to their “forgotten organ”

Linking Genotype to Phenotype: The Effect of a Mutation in Gibberellic Acid Production on Plant Germination

Does Organelle Shape Matter?: Exploring Patterns in Cell Shape and Structure with High-Throughput (HT) Imaging

Investigating Gene Expression and Cell Specialization in Axolotl Embryos

SCIENCE/Fiction: Modular Template for Class Design

An Active Textbook Converts "Vision and Tweak" to Vision and Change

Understanding the Importance of Microtubules in Normal Cell Division: Chemotherapy Connection

Honoring the Complexity of Genetics: Exploring the Role of Genes and the Environment Using Real World Examples

The ACTN3 Polymorphism: Applications in Genetics and Physiology Teaching Laboratories

The Science and Ethics of Gene Drives: An Active Learning Lesson in Genetics

A Journal Club Project to Promote Interpreting and Presenting Information From the Primary Scientific Literature

Differential Gene Expression during Xenopus laevis Development

A Rapid Genetic Screen Using Wisconsin Fast Plants^®: A Hands-On Approach to Inheritance of de novo Mutations

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