CourseSource: Resources

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2560

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641

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Follow the Sulfur: Using Yeast Mutants to Study a Metabolic Pathway

Students are frequently overwhelmed by the complexity of metabolic pathways and they think they have "learned" the pathway when they have memorized the individual reactions. This laboratory lesson helps students to understand the...

Courses: Biochemistry and Molecular Biology Genetics Introductory Biology Microbiology Science Process Skills

SelectionyeastMetabolismcysteinemediamethioninemutantPathwaysulfur

Lesson

2023

views

357

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1

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Interactive Video Vignettes (IVVs) to Help Students Learn Genetics Concepts

Many video resources exist to teach Mendelian genetics, but most consist of passive delivery of information rather than active construction of knowledge by users. We have created two interactive video vignettes (IVVs) that can be used together or...

Courses: Genetics Introductory Biology Science Process Skills

genotypephenotypeallelespedigreedominanceHardy-Weinberg equilibriumInheritance

Lesson

3646

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3314

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0

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Using CRISPR-Cas9 to teach the fundamentals of molecular biology and experimental design

One of the challenges of inquiry-based research experiences is balancing the instruction on skills and techniques with data generation and analysis. This is especially true in technique heavy disciplines such as molecular biology, where emphasis...

Courses: Biochemistry and Molecular Biology

experimental designcrisprmolecular technique

Lesson

2405

views

497

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0

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Translating Co-Translational Translocation

Understanding the process of proteins targeting to specific locations within a cell is a fundamental part of cell biology. Synthesis of proteins by co-translational translocation, which also determines the resulting protein topology, is a complex...

Courses: Cell Biology

Topologyco-translational translocationendoplasmic reticulumprotease protection assaysecretory proteinssignal sequencetransmembrane proteins

Teaching Tools and Strategies

1345

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158

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0

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Integrating Primary Literature in a Lecture Course Using a Modified Version of the C.R.E.A.T.E. Approach

Reforms in undergraduate science education place an increasing emphasis on teaching the skills of practicing scientists, such as reading and interpreting the primary research literature. Many approaches have been proposed to introduce students to...

Courses: Ecology Ecology

primary literatureDiscussionModified JigsawPeer-based Learning

Lesson

3357

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1180

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0

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CRISPR/Cas9 in yeast: a multi-week laboratory exercise for undergraduate students

Providing undergraduate life-science students with a course-based research experience that utilizes cutting-edge technology, is tractable for students, and is manageable as an instructor is a challenge. Here, I describe a multi-week lesson plan...

Courses: Biochemistry and Molecular Biology Bioinformatics Genetics Microbiology Science Process Skills

bioinformaticsPCRphenotypingCRISPR/Cas9gene editingcloningGenotypingRestriction enzyme

Lesson

1986

views

337

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0

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Discovery Poster Project

Engaging in undergraduate research can be exciting yet intimidating to first-year students at large research universities. For first-generation college students, whose pre-college exposure to research may be limited compared to their continuing...

Courses: Introductory Biology Science Process Skills

researchprimary literaturePostercore concepts

Lesson

6119

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1234

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0

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A CURE for Salmonella: A Laboratory Course in Pathogen Microbiology and Genomics

Rapid advances in genomics and bioinformatics, the vast amount of data generated by next-generation sequencing, and the penetration of the ‘-omics’ into many areas of biology have created a need for students with hands-on experience with...

Courses: Biochemistry and Molecular Biology Bioinformatics Ecology Ecology Microbiology

epidemiologyresearchbioinformaticsgenomicspublic healthAntibiotic Resistant BacteriaSalmonellaDNA sequencingpathogenic bacteria

Lesson

1653

views

299

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0

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A Hybrid Virtual Kinesiology Laboratory Module for Human Anatomy and Physiology

The integration of virtual technology is becoming a common trend in anatomy education at the undergraduate and graduate levels. The incorporation of virtual 3D anatomical models into the classroom is beneficial to students, especially if they do...

Courses: Anatomy-Physiology

kinesiologyexercise physiologyAnaerobic RespirationMaximum Oxygen ConsumptionMuscular SystemVirtual AnatomyWingate Test

Teaching Tools and Strategies

2457

views

106

downloads

0

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How to Design a Classroom Activity that Integrates 3D Print Models with Active Learning

Student exploration of relevant physical models can deepen knowledge of course material. In this guide we describe a method by which instructors can integrate 3D printing technology with an established teaching strategy, the classroom jigsaw, to...

Courses: Introductory Biology

active learning3D print modelsclassroom jigsaw

Lesson

2968

views

611

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0

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Using Synthetic Biology and pClone Red for Authentic Research on Promoter Function: Introductory Biology (identifying new promoters)

Students often memorize the definition of a transcriptional promoter but fail to fully understand the critical role promoters play in gene expression. This laboratory lesson allows students to conduct original research by identifying and...

Courses: Genetics Introductory Biology Science Process Skills

bacteriasynthetic biologygene regulationtranscriptionstudent researchcentral dogmacloningpromoterreporter gene/protein

Lesson

1723

views

470

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0

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Generating Biological Hypotheses in a "Course-based Undergraduate Research Experience"(CURE) Course

Hypotheses are often incorrectly defined as educated guesses or if/then statements. Further confusion arises from the fact that not all disciplines define hypotheses similarly. The difficulty in distinguishing between statistical and biological...

Courses: Science Process Skills

scientific methodHPT axisNeural stem cells

Lesson

3785

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1246

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0

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My Dog IS My Homework: Exploring Canine Genetics to Understand Genotype-Phenotype Relationships

To facilitate understanding of the fundamental genetic concept of the genotype-phenotype relationship in our introductory biology students, we designed an engaging multi-week series of related lessons about canine genetics in which students...

Courses: Bioinformatics Genetics Introductory Biology Science Process Skills

gel electrophoresissequence analysiscanine geneticsdeoxyribonucleic acid (DNA)dog coat morphologygenotype and phenotypemutationsPolymerase chain reaction (PCR)single nucleotide polymorphism (SNP)

Lesson

1761

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226

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0

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Using a Sequential Interpretation of Data in Envelopes (SIDE) approach to identify a mystery TRP channel

This lesson sought to engage students in data interpretation and to encourage critical thinking about neurophysiology in the context of temperature sensation. A family of receptors called Transient Receptor Potential (TRP) channels are activated...

Courses: Anatomy-Physiology Cell Biology Neurobiology

Cell communicationChannel specificity and activationLimitations of tools of Cell BiologyNeuronal Signaling

Lesson

2641

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575

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0

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Linking Genotype to Phenotype: The Effect of a Mutation in Gibberellic Acid Production on Plant Germination

Basic concepts in genetics and plant development are often taught in lecture courses without a lab component. This approach provides students with the content knowledge, but fails to make connections to research opportunities and real-world...

Courses: Cell Biology Developmental Biology Genetics Introductory Biology Plant Biology

geneticsdevelopmentmutationgerminationplantmodel organismGenotype/PhenotypeHormoneSeed

Lesson

7958

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396

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Investigating Cell Signaling with Gene Expression Datasets

Modern molecular biology is a data- and computationally-intensive field with few instructional resources for introducing undergraduate students to the requisite skills and techniques for analyzing large data sets. This Lesson helps students: (i)...

Courses: Biochemistry and Molecular Biology Cell Biology

genomicstranscriptionsignaling

Lesson

1149

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164

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0

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Using Musical Instruments to Model Negative Feedback in the Hypothalamo-Pituitary-Target Gland Axes

Homeostasis and negative feedback are crucial, yet difficult, concepts for undergraduates, particularly in the context of the hypothalamo-pituitary axes. This interactive activity was designed to (1) reveal how negative feedback can restore...

Courses: Anatomy-Physiology

cell-cell communicationhomeostasisnegative feedback

Essay

953

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190

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0

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Strategies for developing a science communicator through authentic science writing assignments

To prepare biology undergraduates to be able to read and evaluate the primary literature, it is beneficial to teach students how to write documents in the style of professional science style manuscripts. By breaking manuscripts into individual...

Courses: Science Process Skills

communicationPeer reviewscience writing

Lesson

2044

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890

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0

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Exploration of the Human Genome by Investigation of Personalized SNPs

Students often shy away from tedious bioinformatics approaches to exploring their genomes. However, in our expanding digital world these skills are some of the most relevant and valuable. To increase students' interest in their own genomes, I...

Courses: Bioinformatics Genetics Science Process Skills

UCSC genome browsersingle nucleotide polymorphismGenome wide association studiesGenomic organization

Lesson

1903

views

474

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0

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Why do Some People Inherit a Predisposition to Cancer? A small group activity on cancer genetics

Before undergraduate students take a genetics course they generally know cancer has a genetic basis and involves the proliferation of cells; however, many are uncertain about why only a subset of people have a predisposition to cancer and how that...

Courses: Genetics Science Process Skills

cancerInheritance patternsProbability calculationProto-oncogeneTumor Suppressor Gene

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Follow the Sulfur: Using Yeast Mutants to Study a Metabolic Pathway

Interactive Video Vignettes (IVVs) to Help Students Learn Genetics Concepts

Using CRISPR-Cas9 to teach the fundamentals of molecular biology and experimental design

Translating Co-Translational Translocation

Integrating Primary Literature in a Lecture Course Using a Modified Version of the C.R.E.A.T.E. Approach

CRISPR/Cas9 in yeast: a multi-week laboratory exercise for undergraduate students

Discovery Poster Project

A CURE for Salmonella: A Laboratory Course in Pathogen Microbiology and Genomics

A Hybrid Virtual Kinesiology Laboratory Module for Human Anatomy and Physiology

How to Design a Classroom Activity that Integrates 3D Print Models with Active Learning

Using Synthetic Biology and pClone Red for Authentic Research on Promoter Function: Introductory Biology (identifying new promoters)

Generating Biological Hypotheses in a "Course-based Undergraduate Research Experience"(CURE) Course

My Dog IS My Homework: Exploring Canine Genetics to Understand Genotype-Phenotype Relationships

Using a Sequential Interpretation of Data in Envelopes (SIDE) approach to identify a mystery TRP channel

Linking Genotype to Phenotype: The Effect of a Mutation in Gibberellic Acid Production on Plant Germination

Investigating Cell Signaling with Gene Expression Datasets

Using Musical Instruments to Model Negative Feedback in the Hypothalamo-Pituitary-Target Gland Axes

Strategies for developing a science communicator through authentic science writing assignments

Exploration of the Human Genome by Investigation of Personalized SNPs

Why do Some People Inherit a Predisposition to Cancer? A small group activity on cancer genetics

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