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    Investigating Enzyme Structure and Function Through Model-Building and Peer Teaching in an Introductory Biology Course
    A foundational knowledge of the relationship between structure and function is critical to understanding how enzymes work. The seemingly invisible nature of these molecular interactions makes it challenging for undergraduate students to...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology Introductory BiologyIntroductory Biology

    structure-functionEnzymeallosteric regulationcompetitive inhibitionfeedback inhibitionnoncompetitive inhibitionproductsubstrate
    Lesson
    3020

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    404

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    It's a Substrate... It's a Protein...No - It's an Enzyme! Teaching Using 3D Serine Protease Physical Modeling Activities to Confront Misconceptions.
    Reported misconceptions of enzyme-substrate interactions highlight the necessity for better, targeted instructional tools and assessments. A series of active learning activities with corresponding three-dimensional (3D) physical models were...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology

    Protein StructureEnzymes-Substrate InteractionsNoncovalent InteractionsGeometric ComplementaryElectronicsStereochemistrySerine Proteases
    Lesson
    2981

    views

    349

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    0

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    Serotonin in the Pocket: Non-covalent interactions and neurotransmitter binding
    This lesson introduces beginning biochemistry students to the concept of a biomolecule binding site, such as a neurotransmitter receptor site or an enzyme active site. A simple organic molecule, the neurotransmitter serotonin, is the focus of the...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology

    active sitebindingbinding sitehydrogen bondinghydrophobic effectionic interactionsnon-covalent forces
    Teaching Tools and Strategies
    1480

    views

    234

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    Preparing Student Study Guides through Peer Collaboration in the Technological Era
    Incorporating active learning exercises into large lecture courses is particularly challenging, especially when it comes to examination preparation materials. Traditionally, study guides are used as a tool to guide student learning and review...

    Courses: Introductory BiologyIntroductory Biology Professional Development and Career PlanningProfessional Development and Career Planning Science Process SkillsScience Process Skills

    active learningDiscussionStudy Skills
    Lesson
    3671

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    678

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    0

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    A Hands-on Introduction to Hidden Markov Models
    In this Lesson, we describe a classroom activity that demonstrates how a Hidden Markov Model (HMM) is applied to predict a eukaryotic gene, focusing on predicting one exon-intron boundary. This HMM lesson is part of the BIOL/CS 370...

    Courses: BioinformaticsBioinformatics GeneticsGenetics Science Process SkillsScience Process Skills

    transcriptionexonintronsplicing
    Lesson
    1392

    views

    197

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    0

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    Using Collaborative Projects to Promote Active Learning of Microbial Skin Diseases and Their Impact on Everyday Lives
    One of the most daunting aspects of introductory clinical microbiology is learning details about a vast number of different microbial diseases that can infect humans. Each of these diseases has different causative agents, diagnostic procedures,...

    Courses: MicrobiologyMicrobiology

    infectious diseasecollaborationpathogenesisTreatment of diseasesReal-life Microbiology
    Lesson
    425

    views

    62

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    0

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    The Science and Ethics of Gene Drives: An Active Learning Lesson in Genetics
    Coursework connecting biology to socially relevant issues and ethical questions can help students think about biology in interdisciplinary terms. Gene drives represent one topic involving both advanced biology concepts and societally relevant...

    Courses: GeneticsGenetics

    bioethicsCRISPR/Cas9Genetic modificationGene drives
    Lesson
    4908

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    495

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    0

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    Does Organelle Shape Matter?: Exploring Patterns in Cell Shape and Structure with High-Throughput (HT) Imaging
    Organelle structure has been studied and visualized for decades; however, publicly available databases that use improved high-throughput microscopy of gene-edited cell lines have recently revolutionized the amount and quality of information now...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology BioinformaticsBioinformatics Cell BiologyCell Biology GeneticsGenetics Science Process SkillsScience Process Skills

    modelingcase studymicroscopystructureOrganellesHigh-throughput (HT)Endoplasmic Reticulum (ER)Fluorescent microscopyHuman Cell Biology
    Teaching Tools and Strategies
    5680

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    183

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    Walkabout: An Easy to Use, Experiential Learning Activity for Applying Abstract Concepts to the Real-World
    Students can have difficulty recognizing examples of course concepts in the real-world. They particularly struggle with phenomena that are ambiguously defined, have mimics, or are hard to distinguish from other phenomena. Students can better...

    Courses: EcologyEcology Science Process SkillsScience Process Skills

    data gatheringgreen technologyobservations
    Lesson
    525

    views

    104

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    0

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    An Interrupted Case Study on Urban Prairie Restoration
    Engaging students in meaningful discussions can be a challenging task for science instructors, especially in introductory courses. The story-telling approach used in case studies can increase student participation by demonstrating the relevance of...

    Courses: EcologyEcology Introductory BiologyIntroductory Biology Science Process SkillsScience Process Skills

    urban ecologyPrescribed fireEcosystem Servicesecological restorationwoody encroachmentrangeland ecology
    Teaching Tools and Strategies
    2340

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    190

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    A Pandemic Pivot: Podcast as an Active Engagement Tool in the Classroom and Beyond
    Higher education in STEM undoubtedly integrates the use of technology as a primary mode for content delivery to undergraduate students. This became especially salient throughout the shift to online education during the COVID-19 pandemic. Despite...

    Courses: Science Process SkillsScience Process Skills

    VaccinesReplication of virusesCOVID-19 transmission
    Lesson
    3039

    views

    515

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    0

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    A Kinesthetic Modeling Activity to Teach PCR Fundamentals
    Most molecular biology and biological sciences students understand that the polymerase chain reaction (PCR) is used to amplify DNA. However, we have found that some students experience conceptual misunderstandings, a lack of detailed comprehension...

    Courses: GeneticsGenetics Science Process SkillsScience Process Skills

    PCR
    Lesson
    885

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    91

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    Learning the Landscape: An Active and Applied Lesson on Landscape Ecology for General Ecology Courses
    Landscape ecology is an important subtopic of ecology. As a field, it is inherently interdisciplinary and provides opportunities to teach not only content, but transferable ecological and geographical skills. Given the broad spectrum of topics in...

    Courses: EcologyEcology

    landscape ecologyspatial scaleecosystem managementHabitat fragmentation
    Teaching Tools and Strategies
    1268

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    132

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    Adaptation and Facilitation of Small Group Activities in an Online Introductory Biology Class
    In spring 2020, the sudden mid-semester closure of my campus in response to the global COVID-19 pandemic necessitated a rapid transition to emergency online learning. Consequently, I adapted the small group activities and facilitation methods of...

    Courses: Introductory BiologyIntroductory Biology

    Cellular communicationNeuronal functionNeuronal structure
    Lesson
    1806

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    478

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    Out of Your Seat and on Your Feet! An adaptable course-based research project in plant ecology for advanced students
    University capstone projects can offer science students a rich research experience that illustrates the process of doing scientific research, and can also help students better choose future academic and career pathways. While capstone projects are...

    Courses: EcologyEcology Plant BiologyPlant Biology Science Process SkillsScience Process Skills

    statisticsactive learningecologyinterdisciplinaryplantscommunicating sciencegroup workfield workproces of science
    Lesson
    7666

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    1462

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    An undergraduate bioinformatics curriculum that teaches eukaryotic gene structure
    Gene structure, transcription, translation, and alternative splicing are challenging concepts for many undergraduates studying biology. These topics are typically covered in a traditional lecture environment, but students often fail to master and...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology BioinformaticsBioinformatics GeneticsGenetics

    bioinformaticsGenome BrowsergenomicsRNAseqsplicingComputer ModelGene Structure
    Lesson
    2813

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    769

    downloads

    0

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    Unwrapping Enzyme Kinetics
    Enzyme rates and kinetics are key components used by biochemists to understand how enzymes function. However, students often find it difficult to understand how these experiments are performed and how they reflect enzyme behavior in solution. The...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology

    kineticsstructure-functionenzymescatalysis
    Lesson
    1988

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    376

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    0

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    Engaging Undergraduates in Mechanisms of Tubular Reabsorption and Secretion in the Mammalian Kidney
    If students fail to see the connections among physiological systems, they can become overwhelmed with the amount of information they need to learn. Some students have particular difficulty with the renal system for this reason. This lesson was...

    Courses: Anatomy-PhysiologyAnatomy-Physiology Cell BiologyCell Biology

    OsmosisActive transportMass flowRenal reabsorptionRenal secretionTransport across membranes
    Lesson
    3577

    views

    505

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    0

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    How Many Squirrels Are in the Shrubs? A Lesson Plan for Comparing Methods for Population Estimation
    Estimating the population sizes of animals is a key skill for any student interested in ecology, conservation, or management. However, counting animals in natural habitats is difficult, and the many techniques that exist each rely on assumptions...

    Courses: EcologyEcology Introductory BiologyIntroductory Biology Professional Development and Career PlanningProfessional Development and Career Planning Science Process SkillsScience Process Skills

    population ecologywildlife managementpopulation estimationsciuridaeSquirrel-Net
    Lesson
    3164

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    1094

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    Squirreling Around for Science: Observing Sciurid Rodents to Investigate Animal Behavior
    Hands-on research experiences are important opportunities for students to learn about the nature of inquiry and gain confidence in solving problems. Here, we present an inquiry-based lesson plan that investigates the foraging behavior of sciurid...

    Courses: EcologyEcology Introductory BiologyIntroductory Biology Science Process SkillsScience Process Skills

    foragingbehaviorbehavioral ecologySciuridSquirrelSquirrel-NetTrade-offVigilance