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    Sex and gender: What does it mean to be female or male?
    This lesson provides three activities to engage non-science major students in a discussion about sex, gender, gender identity, and sex determination. Students prepare for the lesson by reading a short article titled Sex and gender: What is the...
    gendersex determinationgender identitysex
    Lesson
    2754

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    537

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    Predicting and classifying effects of insertion and deletion mutations on protein coding regions
    Mutations in genes can affect the encoded proteins in multiple ways, and some of these effects are counterintuitive. As for any other knowledge, students must create their own deep understanding of the Central Dogma. Students may not develop this...
    mutationcentral dogmatranslationframeshift
    Lesson
    999

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    322

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    A first lesson in mathematical modeling for biologists: Rocs
    Using a fictitious population of Rocs, a mythical species of giant raptor, students accomplish two broad objectives: 1) they undertake the process of building a first mathematical model of a population, and 2) they begin to develop their...
    population ecologypopulation modelingdiscrete generationpopulation management
    Lesson
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    353

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    Teaching epidemiology and principles of infectious disease using popular media and the case of Typhoid Mary
    Allied health students often struggle to understand how particular content, such as epidemiology, connects to their future careers. This activity uses the case of Typhoid Mary as a foundation for exploring epidemiology and infectious disease...
    epidemiologycase studyinfectous diseasepopular mediaTyphoid Mary
    Lesson
    2697

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    637

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    Using Synthetic Biology and pClone Red for Authentic Research on Promoter Function: Genetics (analyzing mutant promoters)
    Students often memorize the definition of a transcriptional promoter but fail to fully understand the critical role promoters play in gene expression.  This laboratory lesson allows students to conduct original research by characterizing...
    bacteriasynthetic biologygene regulationtranscriptionstudent researchcentral dogmacloningpromoterreporter gene/protein
    Lesson
    4055

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    1378

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    Teaching Genetic Linkage and Recombination through Mapping with Molecular Markers
    Most introductory genetics courses cover genetic linkage, a core concept in the CourseSource genetics learning outcome framework. Although it is a classical genetics topic, genetic linkage remains an important concept to understand in order to...
    meiosisphenotypegel electrophoresismicrosatellitesBanding PatternGenetic linkageInheritanceMolecular MarkersPhysical Linkage
    Lesson
    1487

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    238

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    Air Quality Data Mining: Mining the US EPA AirData website for student-led evaluation of air quality issues
    Air pollution directly affects human health endpoints including growth, respiratory processes, cardiovascular health, fertility, pregnancy outcomes, and cancer. Therefore, the distribution of air pollution is a topic that is relevant to all, and...
    data miningenvironmental justiceair qualityairpollutionspatial reasoning
    Teaching Tools and Strategies
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    622

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    "Boost your evolution IQ": An evolution misconceptions game
    Students often enter introductory biology courses with misconceptions about evolution. For example, many students believe that traits arise when a species needs them or that evolutionary processes are goal-oriented. To address these and other...

    Courses: EvolutionEvolution

    Evolutionactive learningNatural Selectiongroup workmisconceptions
    Teaching Tools and Strategies
    656

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    Graphical Organizers as Course Road Maps: Using a geologic timescale in a history of life course
    Both major and non-major biology students lack understanding of important evolutionary events, how they are spaced in time, and how they relate back to the earth system. Graphical organizers like concept maps and timescales are popular tools that...

    Courses: EvolutionEvolution

    Evolutionecologyextinctionadaptive radiationdiversification
    Lesson
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    416

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    Why do Some People Inherit a Predisposition to Cancer? A small group activity on cancer genetics
    Before undergraduate students take a genetics course they generally know cancer has a genetic basis and involves the proliferation of cells; however, many are uncertain about why only a subset of people have a predisposition to cancer and how that...
    cancerInheritance patternsProbability calculationProto-oncogeneTumor Suppressor Gene
    Lesson
    1385

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    432

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    Sex-specific differences in Meiosis: Real-world applications
    In traditional classrooms, students are typically presented with facts that they are asked to memorize and recall during an exam.  The rapid explosion of available scientific facts in recent years has made this model of teaching...
    meiosisReproductionAneuploidyGameteNon-disjunctionOocyteSpermTrisomy
    Lesson
    2950

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    641

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    Homologous chromosomes? Exploring human sex chromosomes, sex determination and sex reversal using bioinformatics approaches
    Constructing a robust understanding of homologous chromosomes, sex chromosomes, and the particulate nature of genes is a notoriously difficult task for undergraduate biology students. In this lesson, students expand their knowledge of human...
    bioinformaticsautosomehomologous chromosomeshomologous recombinationsex chromosomesex determinationsex reversal mutations
    Lesson
    2542

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    852

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    Coevolution or not? Crossbills, squirrels and pinecones
    This case reinforces the concept of coevolution as a reciprocal change in genetic structure between or among two or more populations, by having students analyze and interpret data, build a descriptive model of the system, and use data to make...
    fitnessCoevolutionCo-adaptation
    Lesson
    8490

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    1105

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    Why Meiosis Matters: The case of the fatherless snake
    A compelling reason to learn something can make all the difference in students’ motivation to learn it.  Motivation, in turn, is one of the key attitudes that drives learning.  This story presents students with a compelling puzzle of a...
    meiosismitosissex determinationAsexual reproductionParthenogenesis