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    An undergraduate bioinformatics curriculum that teaches eukaryotic gene structure
    Gene structure, transcription, translation, and alternative splicing are challenging concepts for many undergraduates studying biology. These topics are typically covered in a traditional lecture environment, but students often fail to master and...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology BioinformaticsBioinformatics GeneticsGenetics

    bioinformaticsGenome BrowsergenomicsRNAseqsplicingComputer ModelGene Structure
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    3671

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    678

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    A Hands-on Introduction to Hidden Markov Models
    In this Lesson, we describe a classroom activity that demonstrates how a Hidden Markov Model (HMM) is applied to predict a eukaryotic gene, focusing on predicting one exon-intron boundary. This HMM lesson is part of the BIOL/CS 370...

    Courses: BioinformaticsBioinformatics GeneticsGenetics Science Process SkillsScience Process Skills

    transcriptionexonintronsplicing
    Teaching Tools and Strategies
    2183

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    356

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    DNA Detective: Genotype to Phenotype. A Bioinformatics Workshop for Middle School to College.
    Advances in high-throughput techniques have resulted in a rising demand for scientists with basic bioinformatics skills as well as workshops and curricula that teach students bioinformatics concepts. DNA Detective is a workshop we designed to...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology BioinformaticsBioinformatics GeneticsGenetics Plant BiologyPlant Biology

    geneticsbioinformaticsDNAgenotypephenotypegenegene annotation
    Lesson
    1952

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    280

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    A CURE-based approach to teaching genomics using mitochondrial genomes
    There is an abundance (currently over 1016 DNA bases) of publicly available genetic sequence data and a dearth of trained genomicists to process and interpret it, necessitating more trained bioinformaticians with biological expertise. For...

    Courses: BioinformaticsBioinformatics GeneticsGenetics

    proteinsMitochondrial GenomesNuclear GenomesrRNAtRNA
    Lesson
    6519

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    1118

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    Mapping a Mutation to its Gene: The "Fly Lab" as a Modern Research Experience
    Although genetics is an invaluable part of the undergraduate biology curriculum, it can be intimidating to students as well as instructors: Students must reduce their reliance on memorization and dive deep into quantitative analysis, and...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology BioinformaticsBioinformatics GeneticsGenetics Science Process SkillsScience Process Skills

    geneticsbioinformaticsdrosophilachi-square analysiscomplementation mappingmode of inheritancethree-point mapping
    Lesson
    6435

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    4115

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    CURE-all: Large Scale Implementation of Authentic DNA Barcoding Research into First-Year Biology Curriculum
    Growing calls in science education reform have emphasized wide-scale engagement of first-year undergraduate students in authentic research experiences; however, large course enrollments, inadequate student experience, limited resources and...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology BioinformaticsBioinformatics EcologyEcology EvolutionEvolution GeneticsGenetics Introductory BiologyIntroductory Biology Science Process SkillsScience Process Skills

    phylogeneticsbioinformaticsBiodiversityprocess of sciencetaxonomyPCRDNADNA sequencegel electrophoresis
    Lesson
    2322

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    227

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    Sequences and Properties of Gluten Proteins From Different Grains: A Virtual-Friendly Protein Laboratory
    The COVID-19 pandemic has forced much university instruction into virtual modes. As a result, many laboratory courses have either dropped content altogether or replaced hands-on activities with simulations and “dry” labs. Our goal was...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology BioinformaticsBioinformatics

    protein structure and functionProtein sequenceintermolecular forcesBiomacromolecules
    Lesson
    1305

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    183

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    Tying it All Together: An Activity to Help Students Connect Course Experiences to Posted Learning Outcomes
    Instructors of undergraduate courses in Biology and other Science, Technology, Engineering, and Mathematics (STEM) disciplines face an ongoing challenge to foster higher-order thinking and learning skills while also developing a sound conceptual...

    Courses: Anatomy-PhysiologyAnatomy-Physiology BioinformaticsBioinformatics Cell BiologyCell Biology Developmental BiologyDevelopmental Biology EcologyEcology GeneticsGenetics Introductory BiologyIntroductory Biology MicrobiologyMicrobiology NeurobiologyNeurobiology Plant BiologyPlant Biology Science Process SkillsScience Process Skills

    metacognitionreflectiongoalsOutcomes
    Lesson
    4205

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    286

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    Analysis of Microbiomes Using Free Web-Based Tools in Online and In-Person Undergraduate Science Courses
    Our understanding of microbiomes, or the collection of microorganisms and their genes in a given environment, has been revolutionized by technological and computational advances. However, many undergraduate students do not get hands-on experiences...

    Courses: BioinformaticsBioinformatics EcologyEcology MicrobiologyMicrobiology

    microbiomeDNA SubwayCyVerseCourse based undergraduate researchQIIME2ranacapa
    Lesson
    1419

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    224

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    Training future faculty in 30 minutes a week: A modular framework to provide just-in-time professional development to graduate teaching assistants
    Despite increasing recognition of the need to train the teaching assistants (TAs) teaching the majority of STEM lab sections, very few programs report offering sustained teaching professional development opportunities. Here we present a year-long,...

    Courses: Anatomy-PhysiologyAnatomy-Physiology BioinformaticsBioinformatics Cell BiologyCell Biology Developmental BiologyDevelopmental Biology EcologyEcology GeneticsGenetics Introductory BiologyIntroductory Biology MicrobiologyMicrobiology NeurobiologyNeurobiology Plant BiologyPlant Biology Professional Development and Career PlanningProfessional Development and Career Planning

    professional developmentTA TrainingTeaching Assistants
    Lesson
    2357

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    286

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    You and Your Oral Microflora: Introducing non-biology majors to their “forgotten organ”
    With limited time available for laboratory activities, introductory science courses for non-science majors typically use the laboratory period to reinforce material that was previously presented during lecture. This practice was true of a human...

    Courses: GeneticsGenetics Introductory BiologyIntroductory Biology MicrobiologyMicrobiology Science Process SkillsScience Process Skills

    bacteriamicrobiomeBLASTmicrobesDNA replicationPolymerase chain reaction (PCR)
    Lesson
    3137

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    897

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    Fruit Fly Genetics in a Day: A Guided Exploration to Help Many Large Sections of Beginning Students Uncover the Secrets of Sex-linked Inheritance
    Moving beyond the basic concepts of autosomal Mendelian inheritance to sex-linkage can be difficult for introductory biology students. Although crosses with Drosophila fruit flies have long been a mainstay of genetics units that teach these...

    Courses: GeneticsGenetics

    Mendelian Geneticsfruit fly biologysex-linked inheritance