CourseSource: Resources

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A clicker-based case study that untangles student thinking about the processes in the central dogma

The central dogma of biology is a foundational concept that provides a scaffold to understand how genetic information flows in biological systems. Despite its importance, undergraduate students often poorly understand central dogma processes (DNA...

Courses: Genetics Introductory Biology

mutationtranscriptionphenotypecentral dogmatranslationDNA replication

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2989

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346

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A Muscular Dystrophy Case Study Illustrating the Phenotypic Effects of Mutation

Mutations in genes can lead to a variety of phenotypes, including various human diseases. Students often understand that a particular mutation in a single gene causes a disease phenotype, but it is more challenging to illustrate complex genetic...

Courses: Developmental Biology Genetics

mutationProtein Structureethicscentral dogmahuman disease

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3160

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404

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Honoring the Complexity of Genetics: Exploring the Role of Genes and the Environment Using Real World Examples

Historically, undergraduate genetics courses have disproportionately focused on the impact of genes on phenotypes, rather than multifactorial concepts which consider how a combination of genes, the environment, and gene-by-environment interactions...

Courses: Evolution Genetics Introductory Biology

genesenvironmentMendelQuantitative traitsMultifactorialGene by environment interactions

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1952

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280

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A CURE-based approach to teaching genomics using mitochondrial genomes

There is an abundance (currently over 1016 DNA bases) of publicly available genetic sequence data and a dearth of trained genomicists to process and interpret it, necessitating more trained bioinformaticians with biological expertise. For...

Courses: Bioinformatics Genetics

proteinsMitochondrial GenomesNuclear GenomesrRNAtRNA

Lesson

7667

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1462

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An undergraduate bioinformatics curriculum that teaches eukaryotic gene structure

Gene structure, transcription, translation, and alternative splicing are challenging concepts for many undergraduates studying biology. These topics are typically covered in a traditional lecture environment, but students often fail to master and...

Courses: Biochemistry and Molecular Biology Bioinformatics Genetics

bioinformaticsGenome BrowsergenomicsRNAseqsplicingComputer ModelGene Structure

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4805

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770

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Teaching Cancer Biology Through a Lens of Social Justice

The biology classroom is not separate from the greater context of society; social issues can and should be presented in connection with the content. Here we present an example of antiracist teaching using the molecular/cellular biology of cancer...

Courses: Cell Biology

assessmentcancersocial justicePOGILAlignmentPublic ExamPublic

Teaching Tools and Strategies

2183

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356

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DNA Detective: Genotype to Phenotype. A Bioinformatics Workshop for Middle School to College.

Advances in high-throughput techniques have resulted in a rising demand for scientists with basic bioinformatics skills as well as workshops and curricula that teach students bioinformatics concepts. DNA Detective is a workshop we designed to...

Courses: Biochemistry and Molecular Biology Bioinformatics Genetics Plant Biology

geneticsbioinformaticsDNAgenotypephenotypegenegene annotation

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2357

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286

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You and Your Oral Microflora: Introducing non-biology majors to their “forgotten organ”

With limited time available for laboratory activities, introductory science courses for non-science majors typically use the laboratory period to reinforce material that was previously presented during lecture. This practice was true of a human...

Courses: Genetics Introductory Biology Microbiology Science Process Skills

bacteriamicrobiomeBLASTmicrobesDNA replicationPolymerase chain reaction (PCR)

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2158

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469

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Teaching students to read, interpret, and write about scientific research: A press release assignment in a large, lower-division class

A central skill in any science discipline is the ability to read, understand, and discuss the primary literature of the discipline. However, teaching this skill presents unique challenges within large, lower-division courses. To assess our...

Courses: Cell Biology Science Process Skills

cell biologyScience Communicationscientific literacyGraduate Teaching Assistant Professional DevelopmentBiological LiteracyPrimary ResearchWriting Skills

Lesson

3383

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1352

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Using the Cell Engineer/Detective Approach to Explore Cell Structure and Function

As instructors of introductory biology courses for majors and non-majors, we have struggled with teaching the concept of cell structure and function in an engaging way. However, this is a foundational concept that most biology instructors...

Courses: Cell Biology Introductory Biology Science Process Skills

cell functionCell StructureCellular diversityDynamic cellular functionOrganelle function

Lesson

2057

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324

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The Inside and Outside the Body

The Inside and Outside the Body activity helps students develop a conceptual understanding of anatomical barriers such as skin and mucus membranes that separate internal cells and fluids from the external environment. This short exercise prepares...

Courses: Anatomy-Physiology

structureAnatomybarriers

Lesson

1691

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518

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A Remote Introductory Biology Lab Using Backyard Birdwatching to Teach Data Analysis and Communication

Asking questions, designing experiments, collecting data and interpreting those data, and communicating the results are some of the most important concepts an undergraduate biology lab can teach students. When the SARS-CoV2 pandemic forced our...

Courses: Ecology Ecology Introductory Biology Science Process Skills

ecologydata analysisdata collection

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1305

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183

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Tying it All Together: An Activity to Help Students Connect Course Experiences to Posted Learning Outcomes

Instructors of undergraduate courses in Biology and other Science, Technology, Engineering, and Mathematics (STEM) disciplines face an ongoing challenge to foster higher-order thinking and learning skills while also developing a sound conceptual...

Courses: Anatomy-Physiology Bioinformatics Cell Biology Developmental Biology Ecology Ecology Genetics Introductory Biology Microbiology Neurobiology Plant Biology Science Process Skills

metacognitionreflectiongoalsOutcomes

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2644

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460

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Go Extinct! An Award-Winning Evolution Game That Teaches Tree-Thinking as Students Pursue the Winning Strategy

Evolutionary trees communicate both the diversity and unity of life, a central and important scientific concept, as highlighted by the Vision and Change undergraduate biology education movement. Evolutionary trees and cladograms are diagrams...

Courses: Evolution

phylogeneticsnatural historyBiodiversitycladogramCommon ancestorEvolutionary treeLand vertebratesMonophyletic cladeTetrapods

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374

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60

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Environmental Injustice: When the Grass is Greener on the Other Side

Environmental pollution is a global threat that is especially prevalent in heavily industrialized and urbanized areas. Pollution can be found in many forms, such as natural and synthetic pollutants from natural and anthropogenic processes. These...

Courses: Ecology Ecology Introductory Biology Science Process Skills Toxicology

human healthenvironmental injusticeEnvironmental PollutionSystemic BiasesIdeological AwarenessUrban Ecology and Development

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3927

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454

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Is Earth Currently Undergoing a Sixth Mass Extinction?

The five Phanerozoic mass extinctions were central in shaping biodiversity on Earth today. Due to increasing biodiversity losses, there is debate about whether we are currently undergoing a sixth mass extinction. To help students better understand...

Courses: Ecology Ecology Evolution Introductory Biology

conservationBiodiversityextinctionMass ExtinctionDeep Time

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1414

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259

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Expanding the Reach of Crop Plants for Food Security: A Lesson Integrating Non-Majors Students Into the Discussion of Food Diversity and Human Nutrition

University general education (GE) courses host students with various academic backgrounds, interests, and perspectives. Engaging students in GE classes with agricultural issues can be challenging because of the diverse interests of students and...

Courses: Plant Biology Science Process Skills

cereal graincrop diversitycrop yieldglobal food systemhuman nutritionnutrient qualitypseudocereal grainstaple cropunderutilized crop

Lesson

3669

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1005

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A Quick and Simple Natural Selection Role Play

Teaching evolution remains a challenging task in biology education. Students enter the classroom with stubborn misconceptions and many traditional examples of the process of evolution may not resonate with students. This short role play activity...

Courses: Ecology Ecology Evolution Genetics Plant Biology

EvolutionfitnessNatural Selectionheritability

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2919

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362

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Bacteria to Brains in Backyard Coyotes: An Interdisciplinary Pedagogical Case Study

Our interdisciplinary pedagogical case study explores the differences between rural and urban coyotes at the levels of organismal and community ecology. The focus is on how coyotes’ gut microbiomes could affect their behavior via...

Courses: Cell Biology Ecology Ecology Evolution Immunology Introductory Biology Microbiology

dietanimal behaviorimmune systemmicrobiomeNervous systemgut-brain axisImmunoReachdysbiosisCoyoteCytokines

Teaching Tools and Strategies

2540

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211

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An Interactive Protocol for In-Classroom DNA Extraction

Using commonly available materials, this tool allows students to extract DNA, exploring DNA chemistry and the principles of experimental design and execution. We take a “Choose Your Own Adventure” approach encouraging students to...

Courses: Biochemistry and Molecular Biology Genetics Introductory Biology

geneticsDNAbiochemical structure and function

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A clicker-based case study that untangles student thinking about the processes in the central dogma

A Muscular Dystrophy Case Study Illustrating the Phenotypic Effects of Mutation

Honoring the Complexity of Genetics: Exploring the Role of Genes and the Environment Using Real World Examples

A CURE-based approach to teaching genomics using mitochondrial genomes

An undergraduate bioinformatics curriculum that teaches eukaryotic gene structure

Teaching Cancer Biology Through a Lens of Social Justice

DNA Detective: Genotype to Phenotype. A Bioinformatics Workshop for Middle School to College.

You and Your Oral Microflora: Introducing non-biology majors to their “forgotten organ”

Teaching students to read, interpret, and write about scientific research: A press release assignment in a large, lower-division class

Using the Cell Engineer/Detective Approach to Explore Cell Structure and Function

The Inside and Outside the Body

A Remote Introductory Biology Lab Using Backyard Birdwatching to Teach Data Analysis and Communication

Tying it All Together: An Activity to Help Students Connect Course Experiences to Posted Learning Outcomes

Go Extinct! An Award-Winning Evolution Game That Teaches Tree-Thinking as Students Pursue the Winning Strategy

Environmental Injustice: When the Grass is Greener on the Other Side

Is Earth Currently Undergoing a Sixth Mass Extinction?

Expanding the Reach of Crop Plants for Food Security: A Lesson Integrating Non-Majors Students Into the Discussion of Food Diversity and Human Nutrition

A Quick and Simple Natural Selection Role Play

Bacteria to Brains in Backyard Coyotes: An Interdisciplinary Pedagogical Case Study

An Interactive Protocol for In-Classroom DNA Extraction

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