CourseSource: Resources

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A Fun Introductory Command Line Lesson: Next Generation Sequencing Quality Analysis with Emoji!

Radical innovations in DNA sequencing technology over the past decade have created an increased need for computational bioinformatics analyses in the 21st century STEM workforce. Recent evidence however demonstrates that there are significant...

Courses: Bioinformatics

bioinformaticsgenomicscodingJupyter notebookcommand lineCyVersescriptingnext generation sequencing analysis

Lesson

3643

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601

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0

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Teaching RNAseq at Undergraduate Institutions: A tutorial and R package from the Genome Consortium for Active Teaching

Next-generation sequencing is radically changing the study of biology, but there are currently few resources aimed at teaching the required laboratory and data-analysis skills to undergraduate students. This gap is especially true at primarily...

Courses: Bioinformatics Introductory Biology

statisticsbioinformaticsRNAseqgene expressioncomputer programming

Lesson

2879

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776

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0

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Unwrapping Enzyme Kinetics

Enzyme rates and kinetics are key components used by biochemists to understand how enzymes function. However, students often find it difficult to understand how these experiments are performed and how they reflect enzyme behavior in solution. The...

Courses: Biochemistry and Molecular Biology

kineticsstructure-functionenzymescatalysis

Lesson

2086

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325

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0

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The Inside and Outside the Body

The Inside and Outside the Body activity helps students develop a conceptual understanding of anatomical barriers such as skin and mucus membranes that separate internal cells and fluids from the external environment. This short exercise prepares...

Courses: Anatomy-Physiology

structureAnatomybarriers

Lesson

1590

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47

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0

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Leveraging Panel Discussions to Promote Positive Representation, Develop Science Identity, and Shift Stereotypes

The overrepresentation of cis straight white male scientists in examples used in Biology curriculum makes it difficult for students with other axes of diversity (race/ethnicity, gender, sexuality, first-generation college-going, socioeconomic...

Courses: Professional Development and Career Planning

professional developmentEquitydiversityscience identitysense of belongingCentering Student VoicesCareer Paneland InclusionPositive Representation of Diverse ScientistsFostering Community Between Students

Lesson

3193

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409

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0

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Honoring the Complexity of Genetics: Exploring the Role of Genes and the Environment Using Real World Examples

Historically, undergraduate genetics courses have disproportionately focused on the impact of genes on phenotypes, rather than multifactorial concepts which consider how a combination of genes, the environment, and gene-by-environment interactions...

Courses: Evolution Genetics Introductory Biology

genesenvironmentMendelQuantitative traitsMultifactorialGene by environment interactions

Lesson

6482

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4120

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0

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CURE-all: Large Scale Implementation of Authentic DNA Barcoding Research into First-Year Biology Curriculum

Growing calls in science education reform have emphasized wide-scale engagement of first-year undergraduate students in authentic research experiences; however, large course enrollments, inadequate student experience, limited resources and...

Courses: Biochemistry and Molecular Biology Bioinformatics Ecology Ecology Evolution Genetics Introductory Biology Science Process Skills

phylogeneticsbioinformaticsBiodiversityprocess of sciencetaxonomyPCRDNADNA sequencegel electrophoresis

Teaching Tools and Strategies

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141

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Casting a Wide Net via Case Studies: Educating across the undergraduate to medical school continuum in the biological sciences

This article seeks to help bridge undergraduate and medical educators by describing shared educational goals and strategies, highlighting resources relevant for both groups, and exemplifying shared interests through a demonstration resource. Both...

Courses: Genetics

genetic testingdirect-to-consumer genetic testinginformed consentprenatal screeningsecondary findingswhole genome sequencing

Lesson

2169

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470

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Teaching students to read, interpret, and write about scientific research: A press release assignment in a large, lower-division class

A central skill in any science discipline is the ability to read, understand, and discuss the primary literature of the discipline. However, teaching this skill presents unique challenges within large, lower-division courses. To assess our...

Courses: Cell Biology Science Process Skills

cell biologyScience Communicationscientific literacyGraduate Teaching Assistant Professional DevelopmentBiological LiteracyPrimary ResearchWriting Skills

Lesson

2066

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518

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0

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A Simple Method for Predicting a Molecule's Biological Properties From Its Polarity

The distinction between very polar and less polar substances is a foundation of biochemistry, cell biology, and physiology; it surfaces in multiple concept inventories and elaborations of biological core concepts. However, in our experience, most...

Courses: Anatomy-Physiology Biochemistry and Molecular Biology Cell Biology Introductory Biology

Diffusionsolubilitycovalent bondshydrophilichydrophobicpartition coefficientplasma membranepolarity

Lesson

5090

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672

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How Do Kidneys Make Urine From Blood? Qualitative and Quantitative Approaches to Filtration, Secretion, Reabsorption, and Excretion

The function of the kidneys is to help maintain a constant internal environment (homeostasis) by regulating the volume and chemical composition of the blood. This regulation occurs via three fundamental processes: filtration, secretion, and...

Courses: Anatomy-Physiology Introductory Biology

collecting ductexcretionglomerular filtration rate (GFR)nephron tubulereabsorptionrenal corpusclesection

Lesson

6151

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1235

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A CURE for Salmonella: A Laboratory Course in Pathogen Microbiology and Genomics

Rapid advances in genomics and bioinformatics, the vast amount of data generated by next-generation sequencing, and the penetration of the ‘-omics’ into many areas of biology have created a need for students with hands-on experience with...

Courses: Biochemistry and Molecular Biology Bioinformatics Ecology Ecology Microbiology

epidemiologyresearchbioinformaticsgenomicspublic healthAntibiotic Resistant BacteriaSalmonellaDNA sequencingpathogenic bacteria

Teaching Tools and Strategies

2832

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394

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0

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The Flight Physics Concept Inventory: Reliably Evaluating Aerodynamic Lift, Drag and Associated (Naïve) Concepts of Flight in Class and In-Game

Students often struggle to transfer conceptual understanding from isolated instruction to a coherent mental model. This is especially true for the context of flight physics, fluid dynamics, or the concepts of aerodynamic lift, drag, stall, center...

Courses: Introductory Physics: Calculus-Based

active learninggamificationmisconceptionsaerodynamicsfluid dynamicsResearch-based assessment instrumentConceptual SurveyPRE-/POST-test

Teaching Tools and Strategies

1310

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307

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Sanger Sequencing by Hand: Using Paper Clips to Demonstrate Chain Termination

Sanger sequencing is commonly taught with a hands-on approach. Sanger sequencing involves chain termination by dideoxynucleotides, because they are missing the oxygen on the 3’ carbon atom, which is required for the addition of subsequent...

Courses: Genetics

nucleotidessequencingDNAgel electrophoresisChain Termination

Lesson

3012

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352

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A Muscular Dystrophy Case Study Illustrating the Phenotypic Effects of Mutation

Mutations in genes can lead to a variety of phenotypes, including various human diseases. Students often understand that a particular mutation in a single gene causes a disease phenotype, but it is more challenging to illustrate complex genetic...

Courses: Developmental Biology Genetics

mutationProtein Structureethicscentral dogmahuman disease

Review

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238

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Workshop Report: Summer 2020 Virtual CRISPR in the Classroom

As innovations and developments in genome editing technologies using CRISPR-Cas systems progress, the need to disseminate relevant knowledge and build skills among the next generation of young scientists in undergraduate classrooms is vital. Our...

Courses: Biochemistry and Molecular Biology Bioinformatics Genetics Professional Development and Career Planning

geneticscrisprGenome Analysisgene editingbacterial immunity

Essay

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Online Adaptation to "Gotcha! Which fly trap is the best? An introduction to experimental data collection and analysis"

We present here a simple and engaging experiment capitalizing on the universal need to rid our homes of fruit flies to teach experimental design and analysis. In an earlier paper, we described an experiment in which students learn the scientific...

Courses: Science Process Skills

data analysisexperimental designolfaction

Lesson

2416

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369

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Sex and gender: What does it mean to be female or male?

This lesson provides three activities to engage non-science major students in a discussion about sex, gender, gender identity, and sex determination. Students prepare for the lesson by reading a short article titled Sex and gender: What is the...

Courses: Anatomy-Physiology Introductory Biology

gendersex determinationgender identitysex

Teaching Tools and Strategies

3010

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474

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A Strategy for Teaching Undergraduates to Write Effective Scientific Results Sections

Most undergraduate instructors would agree that learning to write about data in the style of a scientific research paper is a worthy goal for their students. However, many hesitate to tackle the challenge of teaching scientific writing in...

Courses: Science Process Skills

data analysisprimary literaturescientific writingcommunicating science

Lesson

2602

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204

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0

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A Laboratory Module That Explores RNA Interference and Codon Optimization Through Fluorescence Microscopy Using Caenorhabditis elegans

Scientific research experiences are beneficial to students allowing them to gain laboratory and problem-solving skills, as well as foundational research skills in a team-based setting. We designed a laboratory module to provide a guided research...

Courses: Bioinformatics Cell Biology Developmental Biology Genetics Science Process Skills

microscopyC. elegansquantitative analysisinquiry-based learninggene expressionRNA interferenceCodon UsageLaboratory Module

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A Fun Introductory Command Line Lesson: Next Generation Sequencing Quality Analysis with Emoji!

Teaching RNAseq at Undergraduate Institutions: A tutorial and R package from the Genome Consortium for Active Teaching

Unwrapping Enzyme Kinetics

The Inside and Outside the Body

Leveraging Panel Discussions to Promote Positive Representation, Develop Science Identity, and Shift Stereotypes

Honoring the Complexity of Genetics: Exploring the Role of Genes and the Environment Using Real World Examples

CURE-all: Large Scale Implementation of Authentic DNA Barcoding Research into First-Year Biology Curriculum

Casting a Wide Net via Case Studies: Educating across the undergraduate to medical school continuum in the biological sciences

Teaching students to read, interpret, and write about scientific research: A press release assignment in a large, lower-division class

A Simple Method for Predicting a Molecule's Biological Properties From Its Polarity

How Do Kidneys Make Urine From Blood? Qualitative and Quantitative Approaches to Filtration, Secretion, Reabsorption, and Excretion

A CURE for Salmonella: A Laboratory Course in Pathogen Microbiology and Genomics

The Flight Physics Concept Inventory: Reliably Evaluating Aerodynamic Lift, Drag and Associated (Naïve) Concepts of Flight in Class and In-Game

Sanger Sequencing by Hand: Using Paper Clips to Demonstrate Chain Termination

A Muscular Dystrophy Case Study Illustrating the Phenotypic Effects of Mutation

Workshop Report: Summer 2020 Virtual CRISPR in the Classroom

Online Adaptation to "Gotcha! Which fly trap is the best? An introduction to experimental data collection and analysis"

Sex and gender: What does it mean to be female or male?

A Strategy for Teaching Undergraduates to Write Effective Scientific Results Sections

A Laboratory Module That Explores RNA Interference and Codon Optimization Through Fluorescence Microscopy Using Caenorhabditis elegans

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