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    Using a Primary Cell Culture Model to Study the Neural Extracellular Matrix
    The extracellular matrix (ECM) provides structural support to cells, but also has key roles in mediating cell adhesion, cell signaling, and differentiation. While this topic is discussed in the lecture setting, it is not heavily studied in...
    Neural extracellular matrixPerineuronal netPrimary neuronal culture
    Lesson
    1550

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    312

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    Cutthroat trout in Colorado: A case study connecting evolution and conservation
    Evaluation of evidence is a key process skill for the core competencies of applying the process of science and using quantitative reasoning. This case study enables upper-division biology students to practice these skills by applying evolutionary...
    population geneticsphylogeneticsSpeciationdivergencegene flow
    Lesson
    1490

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    432

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    Ain't No Mountain Pine Enough: A Case Study of How Mountain Pine Beetles are Affecting Ecosystem Processes
    This case study engages students in generating hypotheses and predictions, analyzing and interpreting data, critically evaluating contrasting results in science, and thinking about feedbacks between biota and abiotic ecosystem dynamics. To address...

    Courses: EcologyEcology

    population biologycarbon cyclingSpecies-habitat interactions
    Lesson
    1414

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    426

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    Generating Biological Hypotheses in a "Course-based Undergraduate Research Experience"(CURE) Course
    Hypotheses are often incorrectly defined as educated guesses or if/then statements. Further confusion arises from the fact that not all disciplines define hypotheses similarly. The difficulty in distinguishing between statistical and biological...
    scientific methodHPT axisNeural stem cells
    Lesson
    2372

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    465

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    Harnessing the Power of the Immune System: Influenza Vaccines
    Because most people have been infected by and/or immunized against influenza, students should know how the immune system responds to the infection and how vaccines protect against disease. Vaccines have played an instrumental role in disease...
    VaccinesInfluenzaImmunizationVaccine efficacy
    Lesson
    1395

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    475

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    Doctor in the House: Improving Undergraduate Critical Thinking Skills Through Diagnosing Medical Case Studies
    Students in undergraduate anatomy and physiology courses are not often exposed to clinical examples of homeostatic imbalances, particularly ones that provide an opportunity to diagnose a medical case. We designed a set of medical cases...
    medicinediagnosiscardiovasculardeductive reasoningdigestiveEndocrinehomeostatic imbalancehypothetico-deductive modelurinary
    Lesson
    2245

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    791

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    Exploring Species Interactions with "Snapshot Serengeti"
    Authentic learning experiences are a valuable way for students to gain an in-depth understanding of the scientific process. However, implementing such experiences in large enrollment courses can be challenging. Here, we present a community ecology...

    Courses: EcologyEcology

    ecologyspecies interactionscitizen scienceCommunity Ecologyanimal behaviorScience Communicationmigrationanimal activityspecies distribution
    Essay
    1260

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    116

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    Going Remote: An Online Adaptation to Using a Primary Cell Culture Model to Study the Neural Extracellular Matrix
    In light of the COVID-19 pandemic, instructors have modified materials to transition to a remote learning platform. The challenge for science instructors has been to design lab exercises that incorporate both active and experiential learning. In...
    remote learningExtracellular matrixNeural extracellular matrixPerineuronal net
    Lesson
    2966

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    1234

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    Using the Cell Engineer/Detective Approach to Explore Cell Structure and Function
    As instructors of introductory biology courses for majors and non-majors, we have struggled with teaching the concept of cell structure and function in an engaging way.  However, this is a foundational concept that most biology instructors...
    cell functionCell StructureCellular diversityDynamic cellular functionOrganelle function
    Lesson
    1175

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    397

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    Using Images of Foraging Leaf-Cutter Ants to Teach Linear Regression
    This lesson offers students a realistic, open-inquiry research experience, even when lab or field research is not possible. We first introduce students to leaf-cutter ants and how they forage. Then we provide images and videos of foraging...
    linear regressionexperimental designPlant-insect interactionsSymbiosisForaging behavior
    Lesson
    1265

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    119

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    Starting Conversations About Discrimination Against Women in STEM
    Many scientists know about — and experience — discrimination against women. In this professional development lesson, graduate students, postdoctoral fellows, faculty, and other career scientists brainstorm ways to intervene and support...
    identityracismGender discriminationIntersectionalityMicroagressionsSexismSexual assaultSexual harassmentTrolling
    Lesson
    3636

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    1089

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    What is Speciation, How Does It Occur, and Why Is It Important for Conservation?
    Speciation provides a framework for classifying biodiversity on Earth and is a central concept in evolutionary biology. To help undergraduate students learn about speciation, we designed a student-centered lesson that uses active-learning...
    EvolutionconservationGenetic DriftSpeciationNatural SelectionBiological species conceptgene flowMorphological species conceptPhylogenetic species concept
    Lesson
    843

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    192

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    Exploring the Broader Impacts of Science and Society in an Active Learning Environment
    Science and society have always been intertwined. Today, scientists are increasingly encouraged to interact with the public by conducting transparent and participatory engaged scholarship, as opposed to the prevailing one-way transfer of...
    active learningsocietyScience CommunicationscienceBroader impactsPublic engagement
    Lesson
    1134

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    168

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    Tying it All Together: An Activity to Help Students Connect Course Experiences to Posted Learning Outcomes
    Instructors of undergraduate courses in Biology and other Science, Technology, Engineering, and Mathematics (STEM) disciplines face an ongoing challenge to foster higher-order thinking and learning skills while also developing a sound conceptual...
    metacognitionreflectiongoalsOutcomes
    Lesson
    1776

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    483

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    Using Immunocytochemistry and Fluorescence Microscopy Imaging to Explore the Mechanism of Action of Anti-Cancer Drugs on the Cell Cycle
    Understanding and visualizing the cell cycle and mitosis is an essential concept of cell biology. This multi-week lab module has students investigate the mechanism of action of anti-cancer drugs that disrupt activities associated with mitosis and...
    fluorescence microscopymitosisCell StructureCell ImagingImmunocytochemistryQuantitative microscopySTEM skills
    Lesson
    2457

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    666

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    Teaching Biodiversity with Museum Specimens in an Inquiry-Based Lab
    In response to the growth of biology datasets and broad efforts to digitize data, an increasingly important skill for science students is the management and analysis of large datasets. We designed an inquiry-based lab module to introduce students...
    data analysisnatural historyphylogenyBiodiversitymammalsAllen's RuleBergmann's Ruleecogeographymuseum research
    Lesson
    955

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    131

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    It's a bird! It's a plane! It's biomechanics!
    Biomechanics is a discipline that draws from physics and engineering principles to understand the movement and structure of living organisms. It is highly interdisciplinary in nature and can be incorporated into general biology and ecology...
    EvolutionecologybatphysiologyAnatomybirdFlightforcesinsect
    Science Behind the Lesson
    1147

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    153

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    The Science Behind the ACTN3 Polymorphism
    A common polymorphism in the alpha-actinin-3 (ACTN3) gene results in the lack of ACTN3 protein expression in fast twitch muscle fibers in ~16% of the human population (1). This genetic change has been linked with muscle performance in humans (2)...
    protein structure and functionhuman genetic variationskeletal muscle physiology
    Lesson
    978

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    285

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    The ACTN3 Polymorphism: Applications in Genetics and Physiology Teaching Laboratories
    Inquiry-based undergraduate laboratories provide the opportunity to engage students in a research experience that improves scientific thinking, but such activities can be difficult to develop and implement due to limited time and resources. We...
    protein structure and functionhuman genetic variationmuscle physiology
    Lesson
    1184

    views

    190

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    Training future faculty in 30 minutes a week: A modular framework to provide just-in-time professional development to graduate teaching assistants
    Despite increasing recognition of the need to train the teaching assistants (TAs) teaching the majority of STEM lab sections, very few programs report offering sustained teaching professional development opportunities. Here we present a year-long,...
    professional developmentTA TrainingTeaching Assistants