CourseSource: Resources

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Coevolution or not? Crossbills, squirrels and pinecones

This case reinforces the concept of coevolution as a reciprocal change in genetic structure between or among two or more populations, by having students analyze and interpret data, build a descriptive model of the system, and use data to make...

Courses: Ecology Ecology Evolution Introductory Biology Science Process Skills

fitnessCoevolutionCo-adaptation

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3171

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1094

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Squirreling Around for Science: Observing Sciurid Rodents to Investigate Animal Behavior

Hands-on research experiences are important opportunities for students to learn about the nature of inquiry and gain confidence in solving problems. Here, we present an inquiry-based lesson plan that investigates the foraging behavior of sciurid...

Courses: Ecology Ecology Introductory Biology Science Process Skills

foragingbehaviorbehavioral ecologySciuridSquirrelSquirrel-NetTrade-offVigilance

Lesson

924

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275

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Population Ecology of the Northern Spotted Owl

The mathematical modeling of populations utilizing field-collected demographic data is an important component of lab curricula in a variety of undergraduate biology lab courses. During the global pandemic brought about by the SARS-CoV-2 virus in...

Courses: Ecology Ecology Introductory Biology

demographyCommunity Ecologypopulation ecologyconservation biologylife tables

Lesson

1452

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156

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The Developmental Origins of Mythology: A Pandemic-Inspired Innovative Developmental Biology Laboratory Exercise

From an experiential, hands-on perspective, the Developmental Biology Laboratory is easily amenable to a wide range of undergraduate-friendly experiments. Thus, pivoting to a virtual laboratory during the COVID-19 pandemic required significant...

Courses: Developmental Biology

gastrulationaxis formationlimb developmentchimeramidline

Lesson

1566

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300

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Using QIIME to Interpret Environmental Microbial Communities in an Upper Level Metagenomics Course

Metagenomics is rapidly evolving due to advances in sequencing technologies and bioinformatics, but without proper training to interpret these datasets, student understanding remains limited. Aimed at undergraduate juniors and seniors and graduate...

Courses: Biochemistry and Molecular Biology Bioinformatics Ecology Ecology Microbiology Science Process Skills

microbiome

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3471

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725

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Homologous chromosomes? Exploring human sex chromosomes, sex determination and sex reversal using bioinformatics approaches

Constructing a robust understanding of homologous chromosomes, sex chromosomes, and the particulate nature of genes is a notoriously difficult task for undergraduate biology students. In this lesson, students expand their knowledge of human...

Courses: Bioinformatics Genetics Introductory Biology Science Process Skills

bioinformaticsautosomehomologous chromosomeshomologous recombinationsex chromosomesex determinationsex reversal mutations

Teaching Tools and Strategies

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1719

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A 360˚ View of COVID-19

In March 2020, institutions underwent a massive transition to distance learning as a result of the COVID-19 pandemic. With so little time to devise new materials to maximize learning in the new virtual environment, instructors devised a variety of...

Courses: Biochemistry and Molecular Biology Bioinformatics Cell Biology Evolution Genetics Immunology Introductory Biology Microbiology Science Process Skills

geneticsImmunologyBiochemistrybioinformaticsmolecular evolutionpublic healthvirusCOVID19

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4909

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495

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Does Organelle Shape Matter?: Exploring Patterns in Cell Shape and Structure with High-Throughput (HT) Imaging

Organelle structure has been studied and visualized for decades; however, publicly available databases that use improved high-throughput microscopy of gene-edited cell lines have recently revolutionized the amount and quality of information now...

Courses: Biochemistry and Molecular Biology Bioinformatics Cell Biology Genetics Science Process Skills

modelingcase studymicroscopystructureOrganellesHigh-throughput (HT)Endoplasmic Reticulum (ER)Fluorescent microscopyHuman Cell Biology

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12331

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1871

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A virtual laboratory on cell division using a publicly-available image database

Cell division is a key concept in cell biology. While there are many popular activities to teach students the stages of mitosis, most make use of simple schematics, cartoons, or textbook diagrams. Others engage students in acting out the stages,...

Courses: Cell Biology Science Process Skills

image analysismicroscopymitosisCellular Processes

Lesson

1809

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479

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Out of Your Seat and on Your Feet! An adaptable course-based research project in plant ecology for advanced students

University capstone projects can offer science students a rich research experience that illustrates the process of doing scientific research, and can also help students better choose future academic and career pathways. While capstone projects are...

Courses: Ecology Ecology Plant Biology Science Process Skills

statisticsactive learningecologyinterdisciplinaryplantscommunicating sciencegroup workfield workproces of science

Lesson

2708

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83

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An Inquiry-Based Project Added to Traditional Labs: Hands-On Fish Awareness Research in Freshwater Systems Conducted by First-Year Biology Students

This project involves students in an inquiry-based project added to the introductory biology laboratory course for majors in fall 2019. Research has shown that student engagement in authentic research has significant positive impacts on...

Courses: Introductory Biology Science Process Skills

Evolutionbehaviorichthyology

Lesson

6614

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1646

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Single Cell Insights Into Cancer Transcriptomes: A Five-Part Single-Cell RNAseq Case Study Lesson

There is a growing need for integration of “Big Data” into undergraduate biology curricula. Transcriptomics is one venue to examine biology from an informatics perspective. RNA sequencing has largely replaced the use of microarrays for whole...

Courses: Biochemistry and Molecular Biology Bioinformatics Cell Biology Genetics Introductory Biology

bioinformaticscancertranscriptomicshigh-throughputData wranglingSingle cell RNA sequencingq

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1216

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407

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Your Tax Dollars at Work: A mock grant writing experience centered on scientific process skills

A successful scientist combines skill, creativity, and the art of persuasion to excel in his or her field of study. Critically important for the professional scientist is the ability to not only conduct research, but also to conceive a project and...

Courses: Science Process Skills

researchexperimental designprocess of sciencePeer reviewgrant writingPecha Kuchaproposal

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618

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Predicting and classifying effects of insertion and deletion mutations on protein coding regions

Mutations in genes can affect the encoded proteins in multiple ways, and some of these effects are counterintuitive. As for any other knowledge, students must create their own deep understanding of the Central Dogma. Students may not develop this...

Courses: Bioinformatics Genetics Science Process Skills

mutationcentral dogmatranslationframeshift

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668

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How Do Kidneys Make Urine From Blood? Qualitative and Quantitative Approaches to Filtration, Secretion, Reabsorption, and Excretion

The function of the kidneys is to help maintain a constant internal environment (homeostasis) by regulating the volume and chemical composition of the blood. This regulation occurs via three fundamental processes: filtration, secretion, and...

Courses: Anatomy-Physiology Introductory Biology

collecting ductexcretionglomerular filtration rate (GFR)nephron tubulereabsorptionrenal corpusclesection

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Escape Zoom!: Reviewing Introductory Evolution Content Using an Escape Room Format

Reviewing and integrating key concepts and learning goals at the end of a biology course can be overwhelming to students and instructors alike. Often end-of-term review sessions in preparation for final exams are heavily based on memorization, and...

Courses: Ecology Ecology Evolution Genetics

Evolutionartificial selectionSpeciationextinctionsexual selectionphylogenetic treesmechanisms of evolution

Lesson

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A Classroom Intervention to Reduce Confirmation Bias

STEM students are often unable to recognize cognitive bias in their own disciplines, and simply describing cognitive bias to students has shown to be insufficient to improve critical thinking. However, habitual metacognitive techniques show...

Courses: Science Process Skills

biasprocess of sciencemetacognitionConfirmation BiasCognitive Bias

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Does it pose a threat? Investigating the impact of Bt corn on monarch butterflies

Aspiring scientists know that a hallmark of science is that experiments are repeatable and testable. However, students do not often get opportunities to explore the replicability of science. Using a current “hot topic” of...

Courses: Ecology Ecology Genetics Introductory Biology Science Process Skills

ecologyCommunity EcologyBt cornGenetic modificationMonarch butterflies

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542

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Using Raw Sequence Data to Analyze Tumor Suppressor Mutations

Learning to identify DNA sequence variants from raw sequencing data (electropherograms) is a basic molecular biology skill with applications to basic research and clinical practice. Yet learning to map DNA sequence variants to functional regions...

Courses: Bioinformatics Genetics

bioinformaticsmutationDNAgenomic visualizationparts of a geneclinical consequencesraw data

Lesson

1261

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93

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Gender and Classroom Participation: A Case for Quantitative Analysis

Teaching statistics to students using authentic research is one way to highlight the transferability and value of the material taught in the class. Below we describe an activity in Statistics for Biological and Health Sciences (STAT2510), an...

Courses: Science Process Skills

statisticsgenderpopulationProportionSampleEquality

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Coevolution or not? Crossbills, squirrels and pinecones

Squirreling Around for Science: Observing Sciurid Rodents to Investigate Animal Behavior

Population Ecology of the Northern Spotted Owl

The Developmental Origins of Mythology: A Pandemic-Inspired Innovative Developmental Biology Laboratory Exercise

Using QIIME to Interpret Environmental Microbial Communities in an Upper Level Metagenomics Course

Homologous chromosomes? Exploring human sex chromosomes, sex determination and sex reversal using bioinformatics approaches

A 360˚ View of COVID-19

Does Organelle Shape Matter?: Exploring Patterns in Cell Shape and Structure with High-Throughput (HT) Imaging

A virtual laboratory on cell division using a publicly-available image database

Out of Your Seat and on Your Feet! An adaptable course-based research project in plant ecology for advanced students

An Inquiry-Based Project Added to Traditional Labs: Hands-On Fish Awareness Research in Freshwater Systems Conducted by First-Year Biology Students

Single Cell Insights Into Cancer Transcriptomes: A Five-Part Single-Cell RNAseq Case Study Lesson

Your Tax Dollars at Work: A mock grant writing experience centered on scientific process skills

Predicting and classifying effects of insertion and deletion mutations on protein coding regions

How Do Kidneys Make Urine From Blood? Qualitative and Quantitative Approaches to Filtration, Secretion, Reabsorption, and Excretion

Escape Zoom!: Reviewing Introductory Evolution Content Using an Escape Room Format

A Classroom Intervention to Reduce Confirmation Bias

Does it pose a threat? Investigating the impact of Bt corn on monarch butterflies

Using Raw Sequence Data to Analyze Tumor Suppressor Mutations

Gender and Classroom Participation: A Case for Quantitative Analysis

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