CourseSource: Resources

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Why do Some People Inherit a Predisposition to Cancer? A small group activity on cancer genetics

Before undergraduate students take a genetics course they generally know cancer has a genetic basis and involves the proliferation of cells; however, many are uncertain about why only a subset of people have a predisposition to cancer and how that...

Courses: Genetics Science Process Skills

cancerInheritance patternsProbability calculationProto-oncogeneTumor Suppressor Gene

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4807

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Teaching Cancer Biology Through a Lens of Social Justice

The biology classroom is not separate from the greater context of society; social issues can and should be presented in connection with the content. Here we present an example of antiracist teaching using the molecular/cellular biology of cancer...

Courses: Cell Biology

assessmentcancersocial justicePOGILAlignmentPublic ExamPublic

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Metastatic Mastery: A Case and Game-Based Approach to Learning About Cancer Mechanisms

Mechanisms that contribute to the development of cancer are numerous and complicated, though most can be traced to a set of mutations in cell cycle regulatory genes that throw the process of cell division off balance. Communication of these...

Courses: Biochemistry and Molecular Biology Genetics Introductory Biology

mutationcancertranscriptioncell cycletranslationOncogenesTumor-suppressorp53Transcription factor

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374

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Environmental Injustice: When the Grass is Greener on the Other Side

Environmental pollution is a global threat that is especially prevalent in heavily industrialized and urbanized areas. Pollution can be found in many forms, such as natural and synthetic pollutants from natural and anthropogenic processes. These...

Courses: Ecology Ecology Introductory Biology Science Process Skills Toxicology

human healthenvironmental injusticeEnvironmental PollutionSystemic BiasesIdeological AwarenessUrban Ecology and Development

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4109

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Splicing it Together: Using Primary Data to Explore RNA Splicing and Gene Expression in Large-Lecture Introductory Biology

At the heart of scientific ways of knowing is the systematic collection and analysis of data, which is then used to propose an explanation of how the world works. In this two-day module, students in a large-lecture course are immersed in a...

Courses: Biochemistry and Molecular Biology Cell Biology Genetics Introductory Biology

gene regulationtranscriptiongene expressioncentral dogmarepressoralternative splicingmRNA processingActivatorTranscription factors

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A Student-Led Hearing on the Use of HeLa Cells in Research

In this role-playing case study, students will learn about the HeLa cell line and its origins while examining multiple perspectives surrounding the cell line and its uses. The goal of this case study is for students to use guided questions to...

Courses: Cell Biology Science Process Skills

bioethicsscience policycell culturedebateHeLa cellsinformed consentrole playsocial justice issues

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Cell Signaling Pathways - a Case Study Approach

Signaling and gene expression are fundamental to cell biology and developmental biology. Although these topics are highly interrelated, they typically appear in separate units in a course. We use a series of short problem-based learning exercises...

Courses: Cell Biology Developmental Biology

signal transductiongene expressionCell communicationgenetic disordersregulation of enzyme activity

Teaching Tools and Strategies

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Science “Fails”: A Bank of Historical Examples for Learning From Failure in Science

Learning from failure is critically important to the processes of scientific inquiry, discovery, and invention. However, students are not routinely taught how to reflect on, learn from, and ultimately embrace failure, and relatively few curricular...

Courses: Introductory Physics: Calculus-Based Introductory Biology Professional Development and Career Planning Science Process Skills

metacognitionScience process skillsLearning from failurepower and privilegestudent wellbeing

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Engaging Students in Pharmacogenetics: Patient Case Studies Using the PharmGKB Website

Cytochrome P450 (CYP) enzymes are important regulators of drug efficacy and toxicity. Genetic variation in CYP isoforms can impact how well patients respond to medications or experience unwanted toxicities. PharmGKB is an online pharmacogenomics...

Courses: Genetics Toxicology

toxicologyPharmacologydrug metabolismpharmacodynamicspharmacogenetics

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Garden Variety Mutations: Using Primary Data to Understand the Central Dogma in Large-Lecture Introductory Biology

The ability to interpret and create an argument from data is a crucial skill for budding scientists, yet one that is seldom practiced in introductory courses. During this argumentation module, students in a large lecture class will work in groups...

Courses: Biochemistry and Molecular Biology Genetics Introductory Biology

mutationtranscriptiongene expressioncentral dogmatranslationgel electrophoresisGenotype/Phenotype

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Introducing Immunology Research Literature to Understand B-cell Receptor Gene Expression

Immunology is relevant to our everyday lives, driving a need for more engaging and inclusive undergraduate immunology education. One way to engage a diverse group of learners is by teaching them how to read and interpret the scientific literature....

Courses: Immunology Science Process Skills