CourseSource: Resources

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1956

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A CURE-based approach to teaching genomics using mitochondrial genomes

There is an abundance (currently over 1016 DNA bases) of publicly available genetic sequence data and a dearth of trained genomicists to process and interpret it, necessitating more trained bioinformaticians with biological expertise. For...

Courses: Bioinformatics Genetics

proteinsMitochondrial GenomesNuclear GenomesrRNAtRNA

Teaching Tools and Strategies

1070

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140

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0

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Casting a Wide Net via Case Studies: Educating across the undergraduate to medical school continuum in the biological sciences

This article seeks to help bridge undergraduate and medical educators by describing shared educational goals and strategies, highlighting resources relevant for both groups, and exemplifying shared interests through a demonstration resource. Both...

Courses: Genetics

genetic testingdirect-to-consumer genetic testinginformed consentprenatal screeningsecondary findingswhole genome sequencing

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4843

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1206

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1

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Teaching the Central Dogma Using a Case Study of Genetic Variation in Cystic Fibrosis

The central dogma of biology is a foundational concept that is traditionally included in genetics curricula at all academic levels. Despite its ubiquitous presence throughout genetics education, students persistently struggle with both the...

Courses: Genetics

transcriptioncentral dogmatranslationsequence analysisDNA replicationgenetic variants

Teaching Tools and Strategies

1867

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384

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0

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Converting a Face-to-Face Lab to Online: An Example of Process and Outcomes for a CRISPR-Based Molecular Biology Lab

The COVID-19 pandemic created a need to convert in-person laboratory courses into an online format in a short amount of time. For this reason, we converted our face-to-face molecular biology lab course to an online version in Spring 2020. The lab...

Courses: Genetics Science Process Skills

mutationtranscriptioncrisprtranslation

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3634

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600

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0

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Teaching RNAseq at Undergraduate Institutions: A tutorial and R package from the Genome Consortium for Active Teaching

Next-generation sequencing is radically changing the study of biology, but there are currently few resources aimed at teaching the required laboratory and data-analysis skills to undergraduate students. This gap is especially true at primarily...

Courses: Bioinformatics Introductory Biology

statisticsbioinformaticsRNAseqgene expressioncomputer programming

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3506

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1299

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A CRISPR/Cas Guide RNA Design In Silico Activity

CRISPR biotechnologies inspired by the Clustered Regularly Interspaced Short Palindromic Repeat RNA-guided nuclease adaptive bacterial immune system have revolutionized biology research and become ubiquitous tools for hypothesis and...

Courses: Biochemistry and Molecular Biology Bioinformatics Cell Biology Genetics

bioinformaticsgene expressiongenetic basis of diseaseCRISPR/Cas9genetic engineeringin silico

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3357

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1180

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CRISPR/Cas9 in yeast: a multi-week laboratory exercise for undergraduate students

Providing undergraduate life-science students with a course-based research experience that utilizes cutting-edge technology, is tractable for students, and is manageable as an instructor is a challenge. Here, I describe a multi-week lesson plan...

Courses: Biochemistry and Molecular Biology Bioinformatics Genetics Microbiology Science Process Skills

bioinformaticsPCRphenotypingCRISPR/Cas9gene editingcloningGenotypingRestriction enzyme

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1906

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474

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Why do Some People Inherit a Predisposition to Cancer? A small group activity on cancer genetics

Before undergraduate students take a genetics course they generally know cancer has a genetic basis and involves the proliferation of cells; however, many are uncertain about why only a subset of people have a predisposition to cancer and how that...

Courses: Genetics Science Process Skills

cancerInheritance patternsProbability calculationProto-oncogeneTumor Suppressor Gene

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2116

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397

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Integrating Manipulatives and Animations to Visualize Holliday Junctions

The complex molecular architecture of Holliday junctions is often challenging for undergraduate biochemistry students to conceptualize. In particular, they have difficulty translating from two-dimensional, linear representations shown in textbooks...

Courses: Biochemistry and Molecular Biology Genetics

dna structureDNA damageDNA recombinationGene crossoverHolliday junction

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1902

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443

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0

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Does it pose a threat? Investigating the impact of Bt corn on monarch butterflies

Aspiring scientists know that a hallmark of science is that experiments are repeatable and testable. However, students do not often get opportunities to explore the replicability of science. Using a current “hot topic” of...

Courses: Ecology Ecology Genetics Introductory Biology Science Process Skills

ecologyCommunity EcologyBt cornGenetic modificationMonarch butterflies

Teaching Tools and Strategies

2790

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271

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0

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The Pipeline CURE: An Iterative Approach to Introduce All Students to Research Throughout a Biology Curriculum

Participation in research provides personal and professional benefits for undergraduates. However, some students face institutional barriers that prevent their entry into research, particularly those from underrepresented groups who may stand to...

Courses: Developmental Biology Genetics Introductory Biology Science Process Skills

epigeneticsundergraduate researchmendelian inheritanceSelf-EfficacyCUREsnature of scienceResiliencecurriculum strategiesreprogramming

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1697

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285

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0

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Using Comics to Make Science Come Alive

Students often see science as a fragmented set of facts to be memorized, rather than concepts and processes that are relevant in their everyday lives. This is especially true for non-science majors, who represent the vast majority of all college...

Courses: Ecology Ecology Genetics Introductory Biology Neurobiology

role of science in society

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1500

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128

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0

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Starting Conversations About Discrimination Against Women in STEM

Many scientists know about — and experience — discrimination against women. In this professional development lesson, graduate students, postdoctoral fellows, faculty, and other career scientists brainstorm ways to intervene and support...

Courses: Professional Development and Career Planning

identityracismGender discriminationIntersectionalityMicroagressionsSexismSexual assaultSexual harassmentTrolling

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6404

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671

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0

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An Active Learning Workshop to Teach Active Learning Strategies

College instructors who learn how to teach actively at the beginning of their careers do not have to modify deeply set habits that rely on lectures. Instead, they develop their teaching while they learn evidence-based practices. We developed a...

Courses: Professional Development and Career Planning

professional developmentActive-learning strategiesjigsawthink-pair-sharePedagogical approachesGallery WalkSmall group discussionInclusive practices

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224

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Training future faculty in 30 minutes a week: A modular framework to provide just-in-time professional development to graduate teaching assistants

Despite increasing recognition of the need to train the teaching assistants (TAs) teaching the majority of STEM lab sections, very few programs report offering sustained teaching professional development opportunities. Here we present a year-long,...

Courses: Anatomy-Physiology Bioinformatics Cell Biology Developmental Biology Ecology Ecology Genetics Introductory Biology Microbiology Neurobiology Plant Biology Professional Development and Career Planning

professional developmentTA TrainingTeaching Assistants

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1412

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Dilution and Pipetting Lesson Using Food Dyes

In this lesson students learn how to use micropipettors to accurately measure small volumes of liquids and perform dilutions using food dyes. Students dilute four food dyes at 10X concentration to 1X working stocks. Using the formula c1v1=c2v2...

Courses: Science Process Skills

dilutionCalculationLab SkillsMicropipetting

Teaching Tools and Strategies

2550

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379

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A Remote-Learning Framework for Student Research Projects: Using Datasets to Teach Experimental Design, Data Analysis and Science Communication

Remote learning often requires an alternative to hands-on, student-designed research projects. To this end, we created a package of scaffolded assignments to support introductory students through the research process using datasets from past...

Courses: Introductory Biology Science Process Skills

population growthphysiologyecotoxicologyphotosynthesis

Lesson

3291

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548

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A Student-Led Hearing on the Use of HeLa Cells in Research

In this role-playing case study, students will learn about the HeLa cell line and its origins while examining multiple perspectives surrounding the cell line and its uses. The goal of this case study is for students to use guided questions to...

Courses: Cell Biology Science Process Skills

bioethicsscience policycell culturedebateHeLa cellsinformed consentrole playsocial justice issues

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2688

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496

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Harnessing the Power of the Immune System: Influenza Vaccines

Because most people have been infected by and/or immunized against influenza, students should know how the immune system responds to the infection and how vaccines protect against disease. Vaccines have played an instrumental role in disease...

Courses: Biochemistry and Molecular Biology Immunology Science Process Skills

VaccinesInfluenzaImmunizationVaccine efficacy

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3671

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1005

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0

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A Quick and Simple Natural Selection Role Play

Teaching evolution remains a challenging task in biology education. Students enter the classroom with stubborn misconceptions and many traditional examples of the process of evolution may not resonate with students. This short role play activity...

Courses: Ecology Ecology Evolution Genetics Plant Biology

EvolutionfitnessNatural Selectionheritability

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A CURE-based approach to teaching genomics using mitochondrial genomes

Casting a Wide Net via Case Studies: Educating across the undergraduate to medical school continuum in the biological sciences

Teaching the Central Dogma Using a Case Study of Genetic Variation in Cystic Fibrosis

Converting a Face-to-Face Lab to Online: An Example of Process and Outcomes for a CRISPR-Based Molecular Biology Lab

Teaching RNAseq at Undergraduate Institutions: A tutorial and R package from the Genome Consortium for Active Teaching

A CRISPR/Cas Guide RNA Design In Silico Activity

CRISPR/Cas9 in yeast: a multi-week laboratory exercise for undergraduate students

Why do Some People Inherit a Predisposition to Cancer? A small group activity on cancer genetics

Integrating Manipulatives and Animations to Visualize Holliday Junctions

Does it pose a threat? Investigating the impact of Bt corn on monarch butterflies

The Pipeline CURE: An Iterative Approach to Introduce All Students to Research Throughout a Biology Curriculum

Using Comics to Make Science Come Alive

Starting Conversations About Discrimination Against Women in STEM

An Active Learning Workshop to Teach Active Learning Strategies

Training future faculty in 30 minutes a week: A modular framework to provide just-in-time professional development to graduate teaching assistants

Dilution and Pipetting Lesson Using Food Dyes

A Remote-Learning Framework for Student Research Projects: Using Datasets to Teach Experimental Design, Data Analysis and Science Communication

A Student-Led Hearing on the Use of HeLa Cells in Research

Harnessing the Power of the Immune System: Influenza Vaccines

A Quick and Simple Natural Selection Role Play

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