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    Vitamin C for Colds? Writing LETTERS to Synthesize and Communicate Results from Multiple Studies
    Interpreting experimental results is a key part of evidence-based reasoning. However, it is challenging for students to synthesize data from multiple sources to reach their own conclusions. As experimental design is increasingly emphasized in...

    Courses: Science Process SkillsScience Process Skills

    pre-healthphysiologyScience Communicationscientific literacyScientific Processconventional wisdomscientific methods
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    2115

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    396

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    Integrating Manipulatives and Animations to Visualize Holliday Junctions
    The complex molecular architecture of Holliday junctions is often challenging for undergraduate biochemistry students to conceptualize. In particular, they have difficulty translating from two-dimensional, linear representations shown in textbooks...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology GeneticsGenetics

    dna structureDNA damageDNA recombinationGene crossoverHolliday junction
    Lesson
    2644

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    460

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    Go Extinct! An Award-Winning Evolution Game That Teaches Tree-Thinking as Students Pursue the Winning Strategy
    Evolutionary trees communicate both the diversity and unity of life, a central and important scientific concept, as highlighted by the Vision and Change undergraduate biology education movement. Evolutionary trees and cladograms are diagrams...

    Courses: EvolutionEvolution

    phylogeneticsnatural historyBiodiversitycladogramCommon ancestorEvolutionary treeLand vertebratesMonophyletic cladeTetrapods
    Lesson
    1191

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    138

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    Understanding the Importance of Microtubules in Normal Cell Division: Chemotherapy Connection
    In introductory courses, students learn about microtubules as important structures but may not engage in a hands-on experience to localize microtubules themselves or to learn about their connection to cancer treatment. In this lesson, students...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology Cell BiologyCell Biology GeneticsGenetics

    cancerCell DivisionimmunofluorescenceMicrotubulesAntibodies
    Lesson
    2145

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    528

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    Using Immunocytochemistry and Fluorescence Microscopy Imaging to Explore the Mechanism of Action of Anti-Cancer Drugs on the Cell Cycle
    Understanding and visualizing the cell cycle and mitosis is an essential concept of cell biology. This multi-week lab module has students investigate the mechanism of action of anti-cancer drugs that disrupt activities associated with mitosis and...

    Courses: Cell BiologyCell Biology Science Process SkillsScience Process Skills

    fluorescence microscopymitosisCell StructureCell ImagingImmunocytochemistryQuantitative microscopySTEM skills
    Lesson
    1220

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    556

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    Understanding Gastric Acid Secretion: An Active Learning Approach
    The human digestive system is a diverse network of cells, tissues, and organs that is regulated by systemic (e.g., nervous and endocrine systems) and local factors (e.g., secretions, pH, and the microbiome). Given the volume of content and the...

    Courses: Anatomy-PhysiologyAnatomy-Physiology

    diseasesignal transductionAcid SecretionAutonomic Nervous SystemEndocrineGastric PhysiologyGPCRHistology of Gastric Pit
    Lesson
    1578

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    350

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    Understanding Protein Domains: A Modular Approach
    An understanding of protein structure, function, and interaction is central to biochemistry. One angle into this topic is to engage students in considering protein domains as modules that develop form and execute function semi-independently. Here,...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology Cell BiologyCell Biology Science Process SkillsScience Process Skills

    Protein Structure
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    7668

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    1462

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    An undergraduate bioinformatics curriculum that teaches eukaryotic gene structure
    Gene structure, transcription, translation, and alternative splicing are challenging concepts for many undergraduates studying biology. These topics are typically covered in a traditional lecture environment, but students often fail to master and...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology BioinformaticsBioinformatics GeneticsGenetics

    bioinformaticsGenome BrowsergenomicsRNAseqsplicingComputer ModelGene Structure
    Lesson
    2836

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    867

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    Exploring Species Interactions with "Snapshot Serengeti"
    Authentic learning experiences are a valuable way for students to gain an in-depth understanding of the scientific process. However, implementing such experiences in large enrollment courses can be challenging. Here, we present a community ecology...

    Courses: EcologyEcology

    ecologyspecies interactionscitizen scienceCommunity Ecologyanimal behaviorScience Communicationmigrationanimal activityspecies distribution
    Essay
    829

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    125

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    Implementing active learning approaches into an upper-division biology course
    In this essay, we present our strategy for implementing active learning strategies into an upper division course on Human Genetics. Our principal goal was to shift from a traditional didactic course design, to one that more clearly placed the...

    Courses: GeneticsGenetics Introductory BiologyIntroductory Biology

    human biologyPedigree analysisRare genetic diseases
    Lesson
    2877

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    1007

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    Building Trees: Introducing evolutionary concepts by exploring Crassulaceae phylogeny and biogeography
    Teaching evolutionary theory is foundational for all biological sciences and a key aspect of overall science literacy. The conceptual framework for understanding evolution relies on thinking clearly about evolutionary trees (phylogenetics) and how...

    Courses: EvolutionEvolution Introductory BiologyIntroductory Biology

    EvolutionphylogeneticsTree thinkingbiogeography
    Lesson
    8524

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    1191

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    Lights, Camera, Acting Transport! Using role-play to teach membrane transport
    Lights, Camera, Acting Transport! is an active and unique role-play exercise designed to teach introductory biology students basic concepts of passive and active membrane transport. The activity involves three acts in which students, representing...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology Cell BiologyCell Biology Introductory BiologyIntroductory Biology

    ATPcarrierschannelsco-transportelectrogenic pumpfacilitated diffusionmembrane transportpassive transportprimary active transportsimple diffusion
    Lesson
    1150

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    165

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    Using Musical Instruments to Model Negative Feedback in the Hypothalamo-Pituitary-Target Gland Axes
    Homeostasis and negative feedback are crucial, yet difficult, concepts for undergraduates, particularly in the context of the hypothalamo-pituitary axes. This interactive activity was designed to (1) reveal how negative feedback can restore...

    Courses: Anatomy-PhysiologyAnatomy-Physiology

    cell-cell communicationhomeostasisnegative feedback