CourseSource: Resources

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The Developmental Origins of Mythology: A Pandemic-Inspired Innovative Developmental Biology Laboratory Exercise

From an experiential, hands-on perspective, the Developmental Biology Laboratory is easily amenable to a wide range of undergraduate-friendly experiments. Thus, pivoting to a virtual laboratory during the COVID-19 pandemic required significant...

Courses: Developmental Biology

gastrulationaxis formationlimb developmentchimeramidline

Lesson

720

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139

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Evaluating Representation in Science Through a Peer-Reviewed Research Study

The demographic representation of scientists featured in biology curricular materials do not match that of the undergraduate biology student population or of the U.S. population. In this lesson, we promote awareness of inequity in science through...

Courses: Introductory Biology

societyRepresentationSTEM equity

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4804

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769

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Teaching Cancer Biology Through a Lens of Social Justice

The biology classroom is not separate from the greater context of society; social issues can and should be presented in connection with the content. Here we present an example of antiracist teaching using the molecular/cellular biology of cancer...

Courses: Cell Biology

assessmentcancersocial justicePOGILAlignmentPublic ExamPublic

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1822

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374

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Exploring Primary Scientific Literature through the Lens of the 5 Core Concepts of Biology

Biology students at the undergraduate level usually excel in knowing biological facts; however, they often struggle with connecting these facts to specific biological principles. In parallel, undergraduate students often struggle to read primary...

Courses: Science Process Skills

5 core conceptsconnecting facts to principlesreading primary scientific literature

Lesson

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547

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An Original-Design Board Game to Increase Student Comprehension of Cellular Respiration Pathways

Cellular respiration is a daunting topic for many students in introductory biology courses. Students are challenged at conceptual and factual levels, since instruction covers multiple metabolic pathways occurring across different cellular...

Courses: Biochemistry and Molecular Biology Cell Biology Introductory Biology Science Process Skills

GlycolysisCellular RespirationFermentationKrebs CycleOxidative phosphorylationpyruvate oxidation

Lesson

7955

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396

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Investigating Cell Signaling with Gene Expression Datasets

Modern molecular biology is a data- and computationally-intensive field with few instructional resources for introducing undergraduate students to the requisite skills and techniques for analyzing large data sets. This Lesson helps students: (i)...

Courses: Biochemistry and Molecular Biology Cell Biology

genomicstranscriptionsignaling

Lesson

5545

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2661

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Cell Signaling Pathways - a Case Study Approach

Signaling and gene expression are fundamental to cell biology and developmental biology. Although these topics are highly interrelated, they typically appear in separate units in a course. We use a series of short problem-based learning exercises...

Courses: Cell Biology Developmental Biology

signal transductiongene expressionCell communicationgenetic disordersregulation of enzyme activity

Lesson

2559

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640

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Follow the Sulfur: Using Yeast Mutants to Study a Metabolic Pathway

Students are frequently overwhelmed by the complexity of metabolic pathways and they think they have "learned" the pathway when they have memorized the individual reactions. This laboratory lesson helps students to understand the...

Courses: Biochemistry and Molecular Biology Genetics Introductory Biology Microbiology Science Process Skills

SelectionyeastMetabolismcysteinemediamethioninemutantPathwaysulfur

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544

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Investigating the Function of a Transport Protein: Where is ABCB6 Located in Human Cells?

One of the challenges of teaching Cell Biology is helping students understand important research methods used to study cells. The goal of understanding cell biology methods is especially challenging in courses without a laboratory...

Courses: Cell Biology

ABC transporter familyDifferential centrifugationImmunoblottingImmunofluorescence assayProtein localizationPurifying organellesSDS-PAGE

Lesson

2141

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496

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0

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Necessary and Sufficient? Solving the Mystery of the Mitochondrial Pyruvate Transporter

While there are several available lessons for teaching introductory biology students about diffusion, facilitated diffusion, and active transport, fewer materials exist to support upper-division students' understanding of the proteins that...

Courses: Cell Biology

DiffusionActive transportfacilitated diffusionNecessary and sufficientTransport proteins

Essay

952

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190

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Strategies for developing a science communicator through authentic science writing assignments

To prepare biology undergraduates to be able to read and evaluate the primary literature, it is beneficial to teach students how to write documents in the style of professional science style manuscripts. By breaking manuscripts into individual...

Courses: Science Process Skills

communicationPeer reviewscience writing

Lesson

3549

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263

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SEAS CURE: Exploring Coral Biology Across Scales

Complex biological concepts (like symbiosis and coral biology) that span multiple scales and cross disciplinary boundaries are often difficult for students to understand. This complexity is compounded by the challenges inherent to teaching and...

Courses: Anatomy-Physiology Cell Biology Ecology Ecology Introductory Biology Science Process Skills

microscopyAnatomySymbiosisMetabolismbleachinginvertebratedinoflagellate

Teaching Tools and Strategies

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A 360˚ View of COVID-19

In March 2020, institutions underwent a massive transition to distance learning as a result of the COVID-19 pandemic. With so little time to devise new materials to maximize learning in the new virtual environment, instructors devised a variety of...

Courses: Biochemistry and Molecular Biology Bioinformatics Cell Biology Evolution Genetics Immunology Introductory Biology Microbiology Science Process Skills

geneticsImmunologyBiochemistrybioinformaticsmolecular evolutionpublic healthvirusCOVID19

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1597

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344

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Investigating Gene Expression and Cell Specialization in Axolotl Embryos

The process of cell specialization is critical to the formation and function of tissues in animals and plants. Although gene expression, including the regulation of transcription, is taught in most introductory cell biology courses, the...

Courses: Biochemistry and Molecular Biology Cell Biology Developmental Biology Science Process Skills

developmenttranscriptiongene expressionmodel organismembryo

Teaching Tools and Strategies

863

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133

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A Team-Based Approach to Course Development Involving Undergraduate Researchers

Development of an undergraduate laboratory course can be a challenge, because of the need to balance both logistical and pedagogical considerations. We piloted a team-based approach to developing this type of course and found it to be advantageous...

Courses: Biochemistry and Molecular Biology Bioinformatics Genetics Microbiology Science Process Skills

student researchcourse development

Teaching Tools and Strategies

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Adaptation and Facilitation of Small Group Activities in an Online Introductory Biology Class

In spring 2020, the sudden mid-semester closure of my campus in response to the global COVID-19 pandemic necessitated a rapid transition to emergency online learning. Consequently, I adapted the small group activities and facilitation methods of...

Courses: Introductory Biology

Cellular communicationNeuronal functionNeuronal structure

Teaching Tools and Strategies

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Preparing Student Study Guides through Peer Collaboration in the Technological Era

Incorporating active learning exercises into large lecture courses is particularly challenging, especially when it comes to examination preparation materials. Traditionally, study guides are used as a tool to guide student learning and review...

Courses: Introductory Biology Professional Development and Career Planning Science Process Skills

active learningDiscussionStudy Skills

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A Modeling Exercise in Sexual Selection using a Student-Created Bird Species

Evolution-centered lessons at the undergraduate level can often be jargon-heavy, propagate misconceptions if taught ineffectively, and be uninteresting to students who may not see the relevancy of such concepts. This activity provides a fun and...

Courses: Ecology Ecology Evolution Introductory Biology

Evolutionfitnesssexual selectionNatural Selectionintersexual selectionmate choice

Lesson

5284

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693

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Investigating Enzyme Structure and Function Through Model-Building and Peer Teaching in an Introductory Biology Course

A foundational knowledge of the relationship between structure and function is critical to understanding how enzymes work. The seemingly invisible nature of these molecular interactions makes it challenging for undergraduate students to...

Courses: Biochemistry and Molecular Biology Introductory Biology

structure-functionEnzymeallosteric regulationcompetitive inhibitionfeedback inhibitionnoncompetitive inhibitionproductsubstrate

Lesson

1248

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65

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Defining Life: Exploring Creativity, Scientific Discovery, and Biology Core Concepts in a Disciplinary First-Year Seminar

This unit, Defining Life, engages students in thinking like scientists, applying creativity to science, and learning biology core concepts as they explore the defining characteristics of life. This unit provides an example of a curriculum designed...

Courses: Biochemistry and Molecular Biology Cell Biology Evolution Genetics Introductory Biology Microbiology Science Process Skills

Evolutionbiologycellprocess of science

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The Developmental Origins of Mythology: A Pandemic-Inspired Innovative Developmental Biology Laboratory Exercise

Evaluating Representation in Science Through a Peer-Reviewed Research Study

Teaching Cancer Biology Through a Lens of Social Justice

Exploring Primary Scientific Literature through the Lens of the 5 Core Concepts of Biology

An Original-Design Board Game to Increase Student Comprehension of Cellular Respiration Pathways

Investigating Cell Signaling with Gene Expression Datasets

Cell Signaling Pathways - a Case Study Approach

Follow the Sulfur: Using Yeast Mutants to Study a Metabolic Pathway

Investigating the Function of a Transport Protein: Where is ABCB6 Located in Human Cells?

Necessary and Sufficient? Solving the Mystery of the Mitochondrial Pyruvate Transporter

Strategies for developing a science communicator through authentic science writing assignments

SEAS CURE: Exploring Coral Biology Across Scales

A 360˚ View of COVID-19

Investigating Gene Expression and Cell Specialization in Axolotl Embryos

A Team-Based Approach to Course Development Involving Undergraduate Researchers

Adaptation and Facilitation of Small Group Activities in an Online Introductory Biology Class

Preparing Student Study Guides through Peer Collaboration in the Technological Era

A Modeling Exercise in Sexual Selection using a Student-Created Bird Species

Investigating Enzyme Structure and Function Through Model-Building and Peer Teaching in an Introductory Biology Course

Defining Life: Exploring Creativity, Scientific Discovery, and Biology Core Concepts in a Disciplinary First-Year Seminar

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