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    Vitamin C for Colds? Writing LETTERS to Synthesize and Communicate Results from Multiple Studies
    Interpreting experimental results is a key part of evidence-based reasoning. However, it is challenging for students to synthesize data from multiple sources to reach their own conclusions. As experimental design is increasingly emphasized in...
    pre-healthphysiologyScience Communicationscientific literacyScientific Processconventional wisdomscientific methods
    Lesson
    2379

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    457

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    Teaching Biodiversity with Museum Specimens in an Inquiry-Based Lab
    In response to the growth of biology datasets and broad efforts to digitize data, an increasingly important skill for science students is the management and analysis of large datasets. We designed an inquiry-based lab module to introduce students...
    data analysisnatural historyphylogenyBiodiversitymammalsAllen's RuleBergmann's Ruleecogeographymuseum research
    Lesson
    940

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    130

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    It's a bird! It's a plane! It's biomechanics!
    Biomechanics is a discipline that draws from physics and engineering principles to understand the movement and structure of living organisms. It is highly interdisciplinary in nature and can be incorporated into general biology and ecology...
    EvolutionecologybatphysiologyAnatomybirdFlightforcesinsect
    Lesson
    1752

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    204

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    The impact of diet and antibiotics on the gut microbiome
    The goal of this article is to describe an active learning exercise that can be used in a variety of advanced microbiology courses, including bacterial physiology, ecology, or systems biology. The gut microbiome is a multi-species bacterial...

    Courses: MicrobiologyMicrobiology

    microbiomeenvironmental controlhost responsemetabolites
    Lesson
    2892

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    1061

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    CRISPR/Cas9 in yeast: a multi-week laboratory exercise for undergraduate students
    Providing undergraduate life-science students with a course-based research experience that utilizes cutting-edge technology, is tractable for students, and is manageable as an instructor is a challenge. Here, I describe a multi-week lesson plan...
    bioinformaticsPCRphenotypingCRISPR/Cas9gene editingcloningGenotypingRestriction enzyme
    Lesson
    1247

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    396

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    Using Structured Decision Making to Explore Complex Environmental Issues
    Environmental issues are inherently complex, often requiring multiple interested parties to come together before agreeing on a solution. Structured decision making is a tool used by federal and state management agencies to find solutions that...

    Courses: EcologyEcology

    interdisciplinarysocio-ecological systemsscience policystakeholderstructured decision making
    Lesson
    3480

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    253

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    Learning to Pipet Correctly by Pipetting Incorrectly?
    Beginning undergraduate students in biology need basic laboratory, data analysis, and science process skills to pursue more complex questions in course-based undergraduate research experiences (CUREs). To this end, we designed an introductory...
    statisticslaboratorypipetting
    Lesson
    7366

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    347

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    Investigating Cell Signaling with Gene Expression Datasets
    Modern molecular biology is a data- and computationally-intensive field with few instructional resources for introducing undergraduate students to the requisite skills and techniques for analyzing large data sets. This Lesson helps students: (i)...
    genomicstranscriptionsignaling
    Lesson
    1692

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    282

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    Discovery Poster Project
    Engaging in undergraduate research can be exciting yet intimidating to first-year students at large research universities. For first-generation college students, whose pre-college exposure to research may be limited compared to their continuing...
    researchprimary literaturePostercore concepts
    Teaching Tools and Strategies
    2198

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    79

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    How to Design a Classroom Activity that Integrates 3D Print Models with Active Learning
    Student exploration of relevant physical models can deepen knowledge of course material. In this guide we describe a method by which instructors can integrate 3D printing technology with an established teaching strategy, the classroom jigsaw, to...
    active learning3D print modelsclassroom jigsaw
    Lesson
    1505

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    197

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    Using a Sequential Interpretation of Data in Envelopes (SIDE) approach to identify a mystery TRP channel
    This lesson sought to engage students in data interpretation and to encourage critical thinking about neurophysiology in the context of temperature sensation. A family of receptors called Transient Receptor Potential (TRP) channels are activated...
    Cell communicationChannel specificity and activationLimitations of tools of Cell BiologyNeuronal Signaling
    Lesson
    1224

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    262

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    Priority Setting in Public Health: A lesson in ethics and hard choices
    Undergraduate life sciences majors, many of whom aspire to work in healthcare and health research, can benefit from early exposure to ethical issues that they may encounter in these careers. This lesson plan introduces students to the tensions...
    public health ethicsramifications of one's decisionsrole of science in society
    Teaching Tools and Strategies
    659

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    97

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    A Team-Based Approach to Course Development Involving Undergraduate Researchers
    Development of an undergraduate laboratory course can be a challenge, because of the need to balance both logistical and pedagogical considerations. We piloted a team-based approach to developing this type of course and found it to be advantageous...
    student researchcourse development
    Review
    2679

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    217

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    Active Learning: Developing Self-Directed Learners Through Strong Intellectual Engagement
    When they were students, many current science instructors learned through traditional lectures. This mode of passive knowledge transmission has been shown to be less effective for student learning than an approach that involves students in a...
    active learningmetacognitionconstructivism
    Lesson
    1252

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    493

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    Investigating the Function of a Transport Protein: Where is ABCB6 Located in Human Cells?
    One of the challenges of teaching Cell Biology is helping students understand important research methods used to study cells.  The goal of understanding cell biology methods is especially challenging in courses without a laboratory...

    Courses: Cell BiologyCell Biology

    ABC transporter familyDifferential centrifugationImmunoblottingImmunofluorescence assayProtein localizationPurifying organellesSDS-PAGE
    Teaching Tools and Strategies
    814

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    110

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    Casting a Wide Net via Case Studies: Educating across the undergraduate to medical school continuum in the biological sciences
    This article seeks to help bridge undergraduate and medical educators by describing shared educational goals and strategies, highlighting resources relevant for both groups, and exemplifying shared interests through a demonstration resource. Both...

    Courses: GeneticsGenetics

    genetic testingdirect-to-consumer genetic testinginformed consentprenatal screeningsecondary findingswhole genome sequencing
    Lesson
    2568

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    315

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    Serotonin in the Pocket: Non-covalent interactions and neurotransmitter binding
    This lesson introduces beginning biochemistry students to the concept of a biomolecule binding site, such as a neurotransmitter receptor site or an enzyme active site. A simple organic molecule, the neurotransmitter serotonin, is the focus of the...
    active sitebindingbinding sitehydrogen bondinghydrophobic effectionic interactionsnon-covalent forces
    Lesson
    1179

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    266

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    Promoting Climate Change Literacy for Non-majors: Implementation of an atmospheric carbon dioxide modeling activity as an inquiry-based classroom activity
    Students who are directly involved in scientific activities develop a deeper understanding and appreciation of both scientific knowledge and the scientific process. This understanding is critically important in scientific areas like climate change...
    modelingExcelquantitativeclimate changeEnvironmental Biologyatmospheric carbon dioxide
    Lesson
    1282

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    271

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    Using QIIME to Interpret Environmental Microbial Communities in an Upper Level Metagenomics Course
    Metagenomics is rapidly evolving due to advances in sequencing technologies and bioinformatics, but without proper training to interpret these datasets, student understanding remains limited. Aimed at undergraduate juniors and seniors and graduate...
    microbiome
    Lesson
    3058

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    487

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    Knowing your own: A classroom case study using the scientific method to investigate how birds learn to recognize their offspring
    Understanding the scientific method provides students with a necessary foundation for careers in science-related fields. Moreover, students can apply scientific inquiry skills in many aspects of their daily lives and decision making. Thus, the...
    scientific methodNatural Selectionbrood parasitism