CourseSource: Resources

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Quantifying Uncertainty and Distinguishing Data Sets in Introductory Physics

Physics labs are moving increasingly to open-ended experiments where students develop experimental physics skills, rather than verify textbook physics concepts. This sequence of activities sets the stage for this new kind of lab early in the...

Courses: Introductory Physics: Calculus-Based

statisticsMeasurementlaboratoryuncertaintypendulumexperimental skills

Teaching Tools and Strategies

5663

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174

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Walkabout: An Easy to Use, Experiential Learning Activity for Applying Abstract Concepts to the Real-World

Students can have difficulty recognizing examples of course concepts in the real-world. They particularly struggle with phenomena that are ambiguously defined, have mimics, or are hard to distinguish from other phenomena. Students can better...

Courses: Ecology Ecology Science Process Skills

data gatheringgreen technologyobservations

Teaching Tools and Strategies

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809

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Science “Fails”: A Bank of Historical Examples for Learning From Failure in Science

Learning from failure is critically important to the processes of scientific inquiry, discovery, and invention. However, students are not routinely taught how to reflect on, learn from, and ultimately embrace failure, and relatively few curricular...

Courses: Introductory Physics: Calculus-Based Introductory Biology Professional Development and Career Planning Science Process Skills

metacognitionScience process skillsLearning from failurepower and privilegestudent wellbeing

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455

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Exploring Miracle Fruit: An Undergraduate Laboratory Exercise on Experimental Design

In recent years, undergraduate biology and biochemistry curricula have seen an increase in the use of course-based undergraduate research experiences (CUREs). CUREs maximize potential student gains when students take an active role in experimental...

Courses: Biochemistry and Molecular Biology Science Process Skills

sensory systemspHProtein shapeTaste

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The Avocado Lab: An Inquiry-Driven Exploration of an Enzymatic Browning Reaction

Typical biochemistry labs exploring basic enzyme activity rely on costly, time-consuming protein purification and rarely explore enzyme function in situ. Further, complex purification procedures leave little room for novelty in experimental...

Courses: Biochemistry and Molecular Biology Introductory Biology

enzymescontrolsenzyme inhibition

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Vitamin C for Colds? Writing LETTERS to Synthesize and Communicate Results from Multiple Studies

Interpreting experimental results is a key part of evidence-based reasoning. However, it is challenging for students to synthesize data from multiple sources to reach their own conclusions. As experimental design is increasingly emphasized in...

Courses: Science Process Skills

pre-healthphysiologyScience Communicationscientific literacyScientific Processconventional wisdomscientific methods

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Why Do I Need a Lab Notebook? Teaching Responsible Conduct of Research with CURE Lab Notebooks

There are few instructional tools about data acquisition and management available for undergraduate students. I created this lesson as a Fellow of the Ethics Network for Course-Based Opportunities in Undergraduate Research (ENCOUR) to fill this...

Courses: Microbiology Professional Development and Career Planning Science Process Skills

lab notebookresponsible conduct of researchdata acquisition/ management

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180

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Simulating Cortical Rotation, Axis Induction, and Experimental Embryology in Amphibian Embryos Using Clay Models

The study of development requires learners to understand spatially complex concepts like embryo anatomy. Embryo anatomy is dynamic over time, and it is often manipulated by researchers in experiments that are fundamental to the field. This spatial...

Courses: Developmental Biology

developmentXenopusfertilizationEmbryologyinductionSymmetry breakingOrganizerCortical rotationPatterning

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Hands-On, Hands-Off: The Community College Genomics (ComGen) Course-Based Undergraduate Research Experience

Science is a process of discovery where failure is inherent and iteration is necessary, yet instructors often teach the scientific process as if it is a controlled, highly supervised, confirmatory practice of following directions to get a known...

Courses: Cell Biology Genetics

geneticssequencingDNAbacterium

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2540

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746

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Using Zebrafish in a Developmental Biology Lab Course to Explore Interactions Between Development and the Environment

Important learning outcomes for biology students include the ability to develop experiments as well as pull together concepts across their coursework. The field of developmental biology, especially environmental influences on development...

Courses: Developmental Biology Science Process Skills

toxicologymorphogenesisorganogenesis

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1129

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180

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Fatty Acid Induction of Lipid Droplets in Cancer Cells

There is a growing need for the development and communication of cell culture-based laboratory activities specifically designed for undergraduate students. This multi-week laboratory activity allows students to take part in the planning,...

Courses: Cell Biology Science Process Skills

Course based undergraduate researchCell ImagingLive Cell Staining

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1719

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597

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Student-Driven Design-and-Improve Modules to Explore the Effect of Plant Bioactive Compounds in Three Model Organisms

Engaging and supporting introductory level students in authentic research experiences during required coursework is challenging. Plant bioactive compounds attract students' natural curiosity as they are found in many familiar items such as...

Courses: Introductory Biology Science Process Skills

statisticsLabCUREInquiryresearch skillscaterpillardaphniadrugsscience process

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634

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Sorry to Eat and Run: A Lesson Plan for Testing Trade-off in Squirrel Behavior Using Giving Up Densities (GUDs)

All animals need to find and compete for food, shelter, and mates in order to survive and reproduce. They also need to avoid being eaten by predators. Optimal foraging theory provides a framework to examine the trade-offs individuals make while...

Courses: Ecology Ecology Evolution Science Process Skills

ecologyanimal behaviorAnimal form and functionAnimal nutritionSquirrel-Net

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258

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Pick Your Poison: A Semester-Long Case Study for Undergraduate Toxicology

The ability to collate information from diverse scientific resources and effectively employ scientific writing is an essential skill for scientists. This lesson describes a semester-long project entitled “Pick Your Poison,” which is...

Courses: Toxicology

risk assessmenttoxicologyPharmacologyregulationsdose responseADME

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624

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Using Bioinformatics and Molecular Visualization to Develop Student Hypotheses in a Malate Dehydrogenase Oriented CURE

Developing student creativity and ability to develop a testable hypothesis represents a significant challenge in most laboratory courses. This lesson demonstrates how students use facets of molecular evolution and bioinformatics approaches...

Courses: Biochemistry and Molecular Biology Bioinformatics Science Process Skills

bioinformaticsNoncovalent InteractionsEnzyme CatalysisProtein Structure/function

Teaching Tools and Strategies

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Integrating Primary Literature in a Lecture Course Using a Modified Version of the C.R.E.A.T.E. Approach

Reforms in undergraduate science education place an increasing emphasis on teaching the skills of practicing scientists, such as reading and interpreting the primary research literature. Many approaches have been proposed to introduce students to...

Courses: Ecology Ecology

primary literatureDiscussionModified JigsawPeer-based Learning

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Bringing Pasteur Back to Life: Studying the Biochemistry of Yeast Fermentation Through Discussion Groups and an At-Home Lab

This hands-on, student-centered biochemistry lesson introduces beginner biochemistry students to the techniques of effectively reading and discussing primary literature, identifying fundamental biological concepts, and applying that knowledge to...

Courses: Biochemistry and Molecular Biology Microbiology Science Process Skills

primary literatureexperimentationyeastMetabolismFermentationRespirationequilibrium

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Harnessing the Power of the Immune System: Influenza Vaccines

Because most people have been infected by and/or immunized against influenza, students should know how the immune system responds to the infection and how vaccines protect against disease. Vaccines have played an instrumental role in disease...

Courses: Biochemistry and Molecular Biology Immunology Science Process Skills

VaccinesInfluenzaImmunizationVaccine efficacy

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Differential Gene Expression during Xenopus laevis Development

In Developmental Biology classes, students are challenged with understanding how differential gene expression guides embryonic development. It can be difficult for students to realize that genes need to be turned on or off at the right time and...

Courses: Developmental Biology

gene expressionXenopusearly developmentembryofertilizationin situ hybridization

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A Short Laboratory Module to Help Infuse Metacognition during an Introductory Course-based Research Experience

A core competency identified in Vision and Change for undergraduate biology students is the Ability to Apply the Process of Science. Here, we describe a three-week laboratory module for students in an Introductory Cell and Molecular Biology...

Courses: Science Process Skills

metacognitiongene expressionScientific ProcessExperimenal DesignHypothesis Generationmodel organisms

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Quantifying Uncertainty and Distinguishing Data Sets in Introductory Physics

Walkabout: An Easy to Use, Experiential Learning Activity for Applying Abstract Concepts to the Real-World

Science “Fails”: A Bank of Historical Examples for Learning From Failure in Science

Exploring Miracle Fruit: An Undergraduate Laboratory Exercise on Experimental Design

The Avocado Lab: An Inquiry-Driven Exploration of an Enzymatic Browning Reaction

Vitamin C for Colds? Writing LETTERS to Synthesize and Communicate Results from Multiple Studies

Why Do I Need a Lab Notebook? Teaching Responsible Conduct of Research with CURE Lab Notebooks

Simulating Cortical Rotation, Axis Induction, and Experimental Embryology in Amphibian Embryos Using Clay Models

Hands-On, Hands-Off: The Community College Genomics (ComGen) Course-Based Undergraduate Research Experience

Using Zebrafish in a Developmental Biology Lab Course to Explore Interactions Between Development and the Environment

Fatty Acid Induction of Lipid Droplets in Cancer Cells

Student-Driven Design-and-Improve Modules to Explore the Effect of Plant Bioactive Compounds in Three Model Organisms

Sorry to Eat and Run: A Lesson Plan for Testing Trade-off in Squirrel Behavior Using Giving Up Densities (GUDs)

Pick Your Poison: A Semester-Long Case Study for Undergraduate Toxicology

Using Bioinformatics and Molecular Visualization to Develop Student Hypotheses in a Malate Dehydrogenase Oriented CURE

Integrating Primary Literature in a Lecture Course Using a Modified Version of the C.R.E.A.T.E. Approach

Bringing Pasteur Back to Life: Studying the Biochemistry of Yeast Fermentation Through Discussion Groups and an At-Home Lab

Harnessing the Power of the Immune System: Influenza Vaccines

Differential Gene Expression during Xenopus laevis Development

A Short Laboratory Module to Help Infuse Metacognition during an Introductory Course-based Research Experience

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