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    Garden Variety Mutations: Using Primary Data to Understand the Central Dogma in Large-Lecture Introductory Biology
    The ability to interpret and create an argument from data is a crucial skill for budding scientists, yet one that is seldom practiced in introductory courses. During this argumentation module, students in a large lecture class will work in groups...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology GeneticsGenetics Introductory BiologyIntroductory Biology

    mutationtranscriptiongene expressioncentral dogmatranslationgel electrophoresisGenotype/Phenotype
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    1776

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    411

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    Teaching epidemiology and principles of infectious disease using popular media and the case of Typhoid Mary
    Allied health students often struggle to understand how particular content, such as epidemiology, connects to their future careers. This activity uses the case of Typhoid Mary as a foundation for exploring epidemiology and infectious disease...

    Courses: MicrobiologyMicrobiology Science Process SkillsScience Process Skills

    epidemiologycase studyinfectous diseasepopular mediaTyphoid Mary
    Lesson
    5153

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    2474

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    Exploring the Lytic and Lysogenic Life Cycles of Bacteriophages
    The goal of this lesson is to introduce students to the lytic and lysogenic cycles of T4 and lambda bacteriophages, respectively, using student-centered pedagogies. Bacteriophages are viruses that infect bacteria and are either virulent or...

    Courses: MicrobiologyMicrobiology

    bacteriophagesLysogenic cycleLysogenyLytic cycle
    Lesson
    3377

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    825

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    Furry with a chance of evolution: Exploring genetic drift with tuco-tucos
    Genetic drift is an important mechanism of evolution, yet undergraduates often fail to understand how it leads to evolutionary change due in part to its random nature. This lesson plan describes a simulation-based activity that allows students to...

    Courses: EvolutionEvolution

    EvolutionGenetic DriftBottle neckFounder effectRandom evolutionary processes
    Lesson
    4037

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    1331

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    Evaluating the Quick Fix: Weight Loss Drugs and Cellular Respiration
    One key to student success in introductory and cell biology courses is a foundational knowledge of cellular respiration. This is a content area in which students often harbor misconceptions that make cellular respiration particularly challenging...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology Cell BiologyCell Biology Introductory BiologyIntroductory Biology

    data analysisCellular RespirationElectron Transport ChainEnergy transformationsMitochondriaOxidative phosphorylationWeight loss drugs24-dinitrophenol (DNP)
    Lesson
    2429

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    457

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    Bad Science: Exploring the unethical research behind a putative memory supplement
    As members of society, students must be able to evaluate scientific claims across a wide variety of media to make sound decisions about health and wellness. However, students - and most members of society - struggle to evaluate the quality of...

    Courses: Science Process SkillsScience Process Skills

    bioethicsevaluationPseudoscienceRecognizing bad scienceScience process skills
    Lesson
    2944

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    395

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    Honoring the Complexity of Genetics: Exploring the Role of Genes and the Environment Using Real World Examples
    Historically, undergraduate genetics courses have disproportionately focused on the impact of genes on phenotypes, rather than multifactorial concepts which consider how a combination of genes, the environment, and gene-by-environment interactions...

    Courses: EvolutionEvolution GeneticsGenetics Introductory BiologyIntroductory Biology

    genesenvironmentMendelQuantitative traitsMultifactorialGene by environment interactions
    Lesson
    1399

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    106

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    Introducing Immunology Research Literature to Understand B-cell Receptor Gene Expression
    Immunology is relevant to our everyday lives, driving a need for more engaging and inclusive undergraduate immunology education. One way to engage a diverse group of learners is by teaching them how to read and interpret the scientific literature....

    Courses: ImmunologyImmunology Science Process SkillsScience Process Skills

    recombinationantibodyV(D)J recombinationB-cell receptorlymphocyte receptor
    Lesson
    3547

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    977

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    A Quick and Simple Natural Selection Role Play
    Teaching evolution remains a challenging task in biology education. Students enter the classroom with stubborn misconceptions and many traditional examples of the process of evolution may not resonate with students. This short role play activity...

    Courses: EcologyEcology EvolutionEvolution GeneticsGenetics Plant BiologyPlant Biology

    EvolutionfitnessNatural Selectionheritability
    Lesson
    2583

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    264

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    The Leaky Neuron: Understanding synaptic integration using an analogy involving leaky cups
    Students have difficulty understanding synaptic integration in neural circuits, and how spatial and temporal summation combine in a target neuron to reach threshold.  This Lesson uses small cups of water to represent excitatory postsynaptic...

    Courses: NeurobiologyNeurobiology

    neuron physiologyspatial summationsynaptic integrationtemporal summationthreshold
    Lesson
    1717

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    308

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    Authentic Ecological Inquiries Using BearCam Archives
    Learning through authentic scientific inquiries is essential for understanding the nature and process of science and for developing critical thinking and communication skills. It is logistically challenging, however, to offer experiences of...

    Courses: EcologyEcology Science Process SkillsScience Process Skills

    behaviorinterspecific interactionsPeer reviewauthentic inquiryintra-specific interactions
    Lesson
    1414

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    468

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    Using Student Perceptions and Cooperative Learning to Unpack Primary Literature on Global Change
    This case describes a three-part assignment in which students discuss key processes that regulate the stability and resilience of the Earth system and our increased risk of generating large-scale abrupt or irreversible environmental changes. Here,...

    Courses: EcologyEcology

    global changeAnthropoceneEarth-systemplanetary boundary conceptthresholds
    Lesson
    2066

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    393

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    Metastatic Mastery: A Case and Game-Based Approach to Learning About Cancer Mechanisms
    Mechanisms that contribute to the development of cancer are numerous and complicated, though most can be traced to a set of mutations in cell cycle regulatory genes that throw the process of cell division off balance. Communication of these...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology GeneticsGenetics Introductory BiologyIntroductory Biology

    mutationcancertranscriptioncell cycletranslationOncogenesTumor-suppressorp53Transcription factor
    Lesson
    1163

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    551

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    Understanding Gastric Acid Secretion: An Active Learning Approach
    The human digestive system is a diverse network of cells, tissues, and organs that is regulated by systemic (e.g., nervous and endocrine systems) and local factors (e.g., secretions, pH, and the microbiome). Given the volume of content and the...

    Courses: Anatomy-PhysiologyAnatomy-Physiology

    diseasesignal transductionAcid SecretionAutonomic Nervous SystemEndocrineGastric PhysiologyGPCRHistology of Gastric Pit
    Lesson
    1626

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    280

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    Using Comics to Make Science Come Alive
    Students often see science as a fragmented set of facts to be memorized, rather than concepts and processes that are relevant in their everyday lives. This is especially true for non-science majors, who represent the vast majority of all college...

    Courses: EcologyEcology GeneticsGenetics Introductory BiologyIntroductory Biology NeurobiologyNeurobiology

    role of science in society
    Lesson
    3990

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    533

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    Splicing it Together: Using Primary Data to Explore RNA Splicing and Gene Expression in Large-Lecture Introductory Biology
    At the heart of scientific ways of knowing is the systematic collection and analysis of data, which is then used to propose an explanation of how the world works. In this two-day module, students in a large-lecture course are immersed in a...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology Cell BiologyCell Biology GeneticsGenetics Introductory BiologyIntroductory Biology

    gene regulationtranscriptiongene expressioncentral dogmarepressoralternative splicingmRNA processingActivatorTranscription factors
    Lesson
    2577

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    487

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    Harnessing the Power of the Immune System: Influenza Vaccines
    Because most people have been infected by and/or immunized against influenza, students should know how the immune system responds to the infection and how vaccines protect against disease. Vaccines have played an instrumental role in disease...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology ImmunologyImmunology Science Process SkillsScience Process Skills

    VaccinesInfluenzaImmunizationVaccine efficacy
    Lesson
    930

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    227

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    Exploring the Broader Impacts of Science and Society in an Active Learning Environment
    Science and society have always been intertwined. Today, scientists are increasingly encouraged to interact with the public by conducting transparent and participatory engaged scholarship, as opposed to the prevailing one-way transfer of...

    Courses: Introductory BiologyIntroductory Biology Professional Development and Career PlanningProfessional Development and Career Planning Science Process SkillsScience Process Skills

    active learningsocietyScience CommunicationscienceBroader impactsPublic engagement
    Lesson
    1151

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    380

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    Your Tax Dollars at Work: A mock grant writing experience centered on scientific process skills
    A successful scientist combines skill, creativity, and the art of persuasion to excel in his or her field of study. Critically important for the professional scientist is the ability to not only conduct research, but also to conceive a project and...

    Courses: Science Process SkillsScience Process Skills

    researchexperimental designprocess of sciencePeer reviewgrant writingPecha Kuchaproposal
    Lesson
    238

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    39

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    Using an Interactive Game, Gutsy, to Examine the Impacts of Pathogens and Everyday Events on the Human Gut Microbiome
    The human gut microbiome is often associated with ‘good bacteria’ in marketing campaigns for dietary supplements, probiotic drinks, and fermented foods. Yet, the dynamic and complex community of microbes that make up the gut microbiome...

    Courses: Anatomy-PhysiologyAnatomy-Physiology ImmunologyImmunology MicrobiologyMicrobiology

    bacteriaGamepathogenhealthmicrobiomediversity