CourseSource: Resources

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Learning Quantitative Genetics: Investigation of Genetic Control for Cold Stress Response in Plants

Course-embedded undergraduate research experiences (CUREs) for students have been shown to increase students’ understanding of the process of science, affirm their scientific identity, and improve retention in STEM fields. Despite many CUREs...

Courses: Genetics

data analysisrecombinationplantsquantitative geneticsabiotic stress responsegenetic control of complex traitsinheritance of complex traits

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3162

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404

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Honoring the Complexity of Genetics: Exploring the Role of Genes and the Environment Using Real World Examples

Historically, undergraduate genetics courses have disproportionately focused on the impact of genes on phenotypes, rather than multifactorial concepts which consider how a combination of genes, the environment, and gene-by-environment interactions...

Courses: Evolution Genetics Introductory Biology

genesenvironmentMendelQuantitative traitsMultifactorialGene by environment interactions

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3497

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853

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Furry with a chance of evolution: Exploring genetic drift with tuco-tucos

Genetic drift is an important mechanism of evolution, yet undergraduates often fail to understand how it leads to evolutionary change due in part to its random nature. This lesson plan describes a simulation-based activity that allows students to...

Courses: Evolution

EvolutionGenetic DriftBottle neckFounder effectRandom evolutionary processes

Lesson

3619

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954

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Life Is Just a Game: An Active Learning Activity to Teach Life History Evolution

A novel activity was designed to introduce students to the concepts of natural selection and life history using an active-learning, constructivist format. It consisted of two parts: 1) a brief introduction to the basic mechanism of natural...

Courses: Ecology Ecology Evolution

Evolutionlife historytrade-offsdiversityNatural Selection

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2434

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166

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A Rapid Genetic Screen Using Wisconsin Fast Plants^®: A Hands-On Approach to Inheritance of de novo Mutations

Some concepts in genetics, such as genetic screens, are complex for students to visualize in a classroom and can be cumbersome to undertake in the laboratory. Typically, very large populations are needed, which can be addressed by using...

Courses: Genetics Plant Biology

mutationInheritancegermlinesomaplant lifecycle

Lesson

2045

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890

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Exploration of the Human Genome by Investigation of Personalized SNPs

Students often shy away from tedious bioinformatics approaches to exploring their genomes. However, in our expanding digital world these skills are some of the most relevant and valuable. To increase students' interest in their own genomes, I...

Courses: Bioinformatics Genetics Science Process Skills

UCSC genome browsersingle nucleotide polymorphismGenome wide association studiesGenomic organization

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2802

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703

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Teaching Biodiversity with Museum Specimens in an Inquiry-Based Lab

In response to the growth of biology datasets and broad efforts to digitize data, an increasingly important skill for science students is the management and analysis of large datasets. We designed an inquiry-based lab module to introduce students...

Courses: Ecology Ecology Evolution Introductory Biology Science Process Skills

data analysisnatural historyphylogenyBiodiversitymammalsAllen's RuleBergmann's Ruleecogeographymuseum research

Lesson

3074

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453

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Moths and Frogs and E. coli, Oh My!: Agent-based Modeling of Evolutionary Systems

In evolution classrooms, introducing and reinforcing the idea of genetic drift and random selection can be challenging, as can be reinforcing appropriate mental models of evolution. Agent-based models offer students the opportunity to conduct a...

Courses: Bioinformatics Ecology Ecology Evolution Science Process Skills

modelingEvolutionecologyagent-based modelingGenetic Driftenvironmental scienceNatural Selectioncompetitive coevolutionsimulation modelingevolutionary reasoning

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1118

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Mapping a Mutation to its Gene: The "Fly Lab" as a Modern Research Experience

Although genetics is an invaluable part of the undergraduate biology curriculum, it can be intimidating to students as well as instructors: Students must reduce their reliance on memorization and dive deep into quantitative analysis, and...

Courses: Biochemistry and Molecular Biology Bioinformatics Genetics Science Process Skills

geneticsbioinformaticsdrosophilachi-square analysiscomplementation mappingmode of inheritancethree-point mapping

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1859

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Teaching Genetic Linkage and Recombination through Mapping with Molecular Markers

Most introductory genetics courses cover genetic linkage, a core concept in the CourseSource genetics learning outcome framework. Although it is a classical genetics topic, genetic linkage remains an important concept to understand in order to...

Courses: Genetics Plant Biology Science Process Skills

meiosisphenotypegel electrophoresismicrosatellitesBanding PatternGenetic linkageInheritanceMolecular MarkersPhysical Linkage

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3670

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1005

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A Quick and Simple Natural Selection Role Play

Teaching evolution remains a challenging task in biology education. Students enter the classroom with stubborn misconceptions and many traditional examples of the process of evolution may not resonate with students. This short role play activity...

Courses: Ecology Ecology Evolution Genetics Plant Biology

EvolutionfitnessNatural Selectionheritability

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393

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Data, Distributions, and Hypotheses: Exploring Diversity and Disturbance in the Tallgrass Prairie

Proper hypothesis generation, data handling, graphing, and communication are essential skills that undergraduate majors in biology are expected to master. However, students rarely get hands-on practice that helps them to effectively develop these...

Courses: Ecology Ecology Plant Biology

Quantitative reasoningRestoration EcologyScience process skillstall grass prairie ecosystem

Teaching Tools and Strategies

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50

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Using Constructed Response Questions on High-Stakes Assessments in Large Classes With Limited Support

Large lecture courses often rely heavily, and sometimes exclusively, on Multiple Choice (MC) exams to assess student learning. Constructed Response (CR) questions, in which students generate their own answers, can provide more insight into student...

Courses: Genetics

assessmenttestexamLarge classconstructed responseshort answerscoring

Science Behind the Lesson

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202

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The Science Behind the ACTN3 Polymorphism

A common polymorphism in the alpha-actinin-3 (ACTN3) gene results in the lack of ACTN3 protein expression in fast twitch muscle fibers in ~16% of the human population (1). This genetic change has been linked with muscle performance in humans (2)...

Courses: Anatomy-Physiology Genetics

protein structure and functionhuman genetic variationskeletal muscle physiology

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357

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Interactive Video Vignettes (IVVs) to Help Students Learn Genetics Concepts

Many video resources exist to teach Mendelian genetics, but most consist of passive delivery of information rather than active construction of knowledge by users. We have created two interactive video vignettes (IVVs) that can be used together or...

Courses: Genetics Introductory Biology Science Process Skills

genotypephenotypeallelespedigreedominanceHardy-Weinberg equilibriumInheritance

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3140

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502

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Targeting Misconceptions in the Central Dogma by Examining Viral Infection

Understanding the central dogma and how changes in gene expression can impact cell function requires integration of several topics in molecular biology. Students often do not make the necessary connections between DNA structure, transcription,...

Courses: Genetics Introductory Biology

datatranscriptionvirustranslationprotein functionmembrane transportPredictions

Lesson

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Defining Life: Exploring Creativity, Scientific Discovery, and Biology Core Concepts in a Disciplinary First-Year Seminar

This unit, Defining Life, engages students in thinking like scientists, applying creativity to science, and learning biology core concepts as they explore the defining characteristics of life. This unit provides an example of a curriculum designed...

Courses: Biochemistry and Molecular Biology Cell Biology Evolution Genetics Introductory Biology Microbiology Science Process Skills

Evolutionbiologycellprocess of science

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My Dog IS My Homework: Exploring Canine Genetics to Understand Genotype-Phenotype Relationships

To facilitate understanding of the fundamental genetic concept of the genotype-phenotype relationship in our introductory biology students, we designed an engaging multi-week series of related lessons about canine genetics in which students...

Courses: Bioinformatics Genetics Introductory Biology Science Process Skills

gel electrophoresissequence analysiscanine geneticsdeoxyribonucleic acid (DNA)dog coat morphologygenotype and phenotypemutationsPolymerase chain reaction (PCR)single nucleotide polymorphism (SNP)

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An Inquiry-Based Project Added to Traditional Labs: Hands-On Fish Awareness Research in Freshwater Systems Conducted by First-Year Biology Students

This project involves students in an inquiry-based project added to the introductory biology laboratory course for majors in fall 2019. Research has shown that student engagement in authentic research has significant positive impacts on...

Courses: Introductory Biology Science Process Skills

Evolutionbehaviorichthyology

Lesson

1840

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241

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Bioinformatics is a BLAST: Engaging First-Year Biology Students on Campus Biodiversity Using DNA Barcoding

In order to introduce students to the concept of molecular diversity, we developed a short, engaging online lesson using basic bioinformatics techniques. Students were introduced to basic bioinformatics while learning about local on-campus species...

Courses: Bioinformatics Introductory Biology

geneticsorganismal biologybioinformaticstaxonomyDNA Barcodingspecies concepts

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Learning Quantitative Genetics: Investigation of Genetic Control for Cold Stress Response in Plants

Honoring the Complexity of Genetics: Exploring the Role of Genes and the Environment Using Real World Examples

Furry with a chance of evolution: Exploring genetic drift with tuco-tucos

Life Is Just a Game: An Active Learning Activity to Teach Life History Evolution

A Rapid Genetic Screen Using Wisconsin Fast Plants^®: A Hands-On Approach to Inheritance of de novo Mutations

Exploration of the Human Genome by Investigation of Personalized SNPs

Teaching Biodiversity with Museum Specimens in an Inquiry-Based Lab

Moths and Frogs and E. coli, Oh My!: Agent-based Modeling of Evolutionary Systems

Mapping a Mutation to its Gene: The "Fly Lab" as a Modern Research Experience

Teaching Genetic Linkage and Recombination through Mapping with Molecular Markers

A Quick and Simple Natural Selection Role Play

Data, Distributions, and Hypotheses: Exploring Diversity and Disturbance in the Tallgrass Prairie

Using Constructed Response Questions on High-Stakes Assessments in Large Classes With Limited Support

The Science Behind the ACTN3 Polymorphism

Interactive Video Vignettes (IVVs) to Help Students Learn Genetics Concepts

Targeting Misconceptions in the Central Dogma by Examining Viral Infection

Defining Life: Exploring Creativity, Scientific Discovery, and Biology Core Concepts in a Disciplinary First-Year Seminar

My Dog IS My Homework: Exploring Canine Genetics to Understand Genotype-Phenotype Relationships

An Inquiry-Based Project Added to Traditional Labs: Hands-On Fish Awareness Research in Freshwater Systems Conducted by First-Year Biology Students

Bioinformatics is a BLAST: Engaging First-Year Biology Students on Campus Biodiversity Using DNA Barcoding

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