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    Teaching Tools and Strategies
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    Casting a Wide Net via Case Studies: Educating across the undergraduate to medical school continuum in the biological sciences
    This article seeks to help bridge undergraduate and medical educators by describing shared educational goals and strategies, highlighting resources relevant for both groups, and exemplifying shared interests through a demonstration resource. Both...

    Courses: GeneticsGenetics

    Lesson
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    Teaching the Central Dogma Using a Case Study of Genetic Variation in Cystic Fibrosis
    The central dogma of biology is a foundational concept that is traditionally included in genetics curricula at all academic levels. Despite its ubiquitous presence throughout genetics education, students persistently struggle with both the...

    Courses: GeneticsGenetics

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    Using Raw Sequence Data to Analyze Tumor Suppressor Mutations
    Learning to identify DNA sequence variants from raw sequencing data (electropherograms) is a basic molecular biology skill with applications to basic research and clinical practice. Yet learning to map DNA sequence variants to functional regions...
    Lesson
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    Modeling Strep Throat Detection, Infection, and Spread Using an SIR Model and the Vensim Simulation Software
    The overarching goal of this lesson is to provide students with an opportunity to gain experience making and using biological models. Biological modeling can be used to investigate complex, real-world problems so that predictions can be made about...
    Teaching Tools and Strategies
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    Biology from Molecules to Embryos, Interactive Animated Lessons
    Visualizing kinetic processes can be an impediment to student mastery of basic science coursework. To remedy this obstacle, I created an educational program called Biology from Molecules to Embryos© (BioME), which provides 28 animated lessons...
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    A Rapid Genetic Screen Using Wisconsin Fast Plants®: A Hands-On Approach to Inheritance of de novo Mutations
    Some concepts in genetics, such as genetic screens, are complex for students to visualize in a classroom and can be cumbersome to undertake in the laboratory. Typically, very large populations are needed, which can be addressed by using...
    Lesson
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    CRISPR/Cas9 in yeast: a multi-week laboratory exercise for undergraduate students
    Providing undergraduate life-science students with a course-based research experience that utilizes cutting-edge technology, is tractable for students, and is manageable as an instructor is a challenge. Here, I describe a multi-week lesson plan...
    Lesson
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    The Comics Project: Synthesizing and Communicating Science with Comics
    Students, especially non-science majors, often see science as abstracted from their daily lives. Moreover, students often struggle to translate scientific concepts into everyday language in order to communicate to their communities what they have...
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    Single Cell Insights Into Cancer Transcriptomes: A Five-Part Single-Cell RNAseq Case Study Lesson
    There is a growing need for integration of “Big Data” into undergraduate biology curricula. Transcriptomics is one venue to examine biology from an informatics perspective. RNA sequencing has largely replaced the use of microarrays for whole...
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    Exploring Primary Scientific Literature through the Lens of the 5 Core Concepts of Biology
    Biology students at the undergraduate level usually excel in knowing biological facts; however, they often struggle with connecting these facts to specific biological principles. In parallel, undergraduate students often struggle to read primary...
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    Differential Gene Expression during Xenopus laevis Development
    In Developmental Biology classes, students are challenged with understanding how differential gene expression guides embryonic development. It can be difficult for students to realize that genes need to be turned on or off at the right time and...
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    Using Synthetic Biology and pClone Red for Authentic Research on Promoter Function: Genetics (analyzing mutant promoters)
    Students often memorize the definition of a transcriptional promoter but fail to fully understand the critical role promoters play in gene expression.  This laboratory lesson allows students to conduct original research by characterizing...
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    A Laboratory Module That Explores RNA Interference and Codon Optimization Through Fluorescence Microscopy Using Caenorhabditis elegans
    Scientific research experiences are beneficial to students allowing them to gain laboratory and problem-solving skills, as well as foundational research skills in a team-based setting. We designed a laboratory module to provide a guided research...
    Lesson
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    Antibiotic Resistance Genes Detection in Environmental Samples
    Our aim is to provide an authentic research experience for undergraduate students in a variety of biology courses through collaboration between a four-year university and a community college. This lab series teaches transferable and universal...
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    The ACTN3 Polymorphism: Applications in Genetics and Physiology Teaching Laboratories
    Inquiry-based undergraduate laboratories provide the opportunity to engage students in a research experience that improves scientific thinking, but such activities can be difficult to develop and implement due to limited time and resources. We...