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    How Do Kidneys Make Urine From Blood? Qualitative and Quantitative Approaches to Filtration, Secretion, Reabsorption, and Excretion
    The function of the kidneys is to help maintain a constant internal environment (homeostasis) by regulating the volume and chemical composition of the blood. This regulation occurs via three fundamental processes: filtration, secretion, and...
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    361

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    Engaging Undergraduates in Mechanisms of Tubular Reabsorption and Secretion in the Mammalian Kidney
    If students fail to see the connections among physiological systems, they can become overwhelmed with the amount of information they need to learn. Some students have particular difficulty with the renal system for this reason. This lesson was...
    Lesson
    1817

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    481

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    A Simple Method for Predicting a Molecule's Biological Properties From Its Polarity
    The distinction between very polar and less polar substances is a foundation of biochemistry, cell biology, and physiology; it surfaces in multiple concept inventories and elaborations of biological core concepts. However, in our experience, most...
    Lesson
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    200

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    Isolation and Functional Analysis of a Pancreatic Enzyme in an Introductory Student Lab
    Structure and function are correlated at all levels of biology. This topic is typically addressed early in an undergraduate class in general or molecular biology before students have gained much skill or knowledge in molecular biology. However, an...
    Lesson
    2582

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    714

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    Unwrapping Enzyme Kinetics
    Enzyme rates and kinetics are key components used by biochemists to understand how enzymes function. However, students often find it difficult to understand how these experiments are performed and how they reflect enzyme behavior in solution. The...
    Lesson
    3468

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    771

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    Breaking Bricks: A Hands-On Model of Enzyme Kinetics and Inhibition
    Enzyme kinetics and the impacts of inhibitors on the enzyme's maximal velocity and ability to bind substrates are important topics in cell biology and biochemistry. However, these topics can be difficult for students to grasp when instructed...
    Lesson
    1612

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    593

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    Student-Driven Design-and-Improve Modules to Explore the Effect of Plant Bioactive Compounds in Three Model Organisms
    Engaging and supporting introductory level students in authentic research experiences during required coursework is challenging. Plant bioactive compounds attract students' natural curiosity as they are found in many familiar items such as...
    Lesson
    2254

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    227

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    Sex and gender: What does it mean to be female or male?
    This lesson provides three activities to engage non-science major students in a discussion about sex, gender, gender identity, and sex determination. Students prepare for the lesson by reading a short article titled Sex and gender: What is the...
    Lesson
    2118

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    403

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    Dynamic Daphnia: An inquiry-based research experience in ecology that teaches the scientific process to first-year biologists
    This authentic research experience lesson teaches the core concept of systems and the competencies of quantitative reasoning, communication, and the ability to apply science. The research is student driven, the results are unknown, and the...
    Lesson
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    282

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    Marsh Madness: Using Video Games and a Case Study to Explore Food Webs and Ecosystem Services in Carpinteria Salt Marsh Reserve
    As the complexity and interconnectedness of our world increases, we are continually expected to be capable of complex, non-linear thinking in order to successfully tackle and solve the challenges we face in the 21st century. Tackling these...

    Courses: EcologyEcology

    Lesson
    443

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    75

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    An Interrupted Case Study on Urban Prairie Restoration
    Engaging students in meaningful discussions can be a challenging task for science instructors, especially in introductory courses. The story-telling approach used in case studies can increase student participation by demonstrating the relevance of...
    Lesson
    1703

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    216

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    Using a Sequential Interpretation of Data in Envelopes (SIDE) approach to identify a mystery TRP channel
    This lesson sought to engage students in data interpretation and to encourage critical thinking about neurophysiology in the context of temperature sensation. A family of receptors called Transient Receptor Potential (TRP) channels are activated...
    Lesson
    3924

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    1288

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    Evaluating the Quick Fix: Weight Loss Drugs and Cellular Respiration
    One key to student success in introductory and cell biology courses is a foundational knowledge of cellular respiration. This is a content area in which students often harbor misconceptions that make cellular respiration particularly challenging...
    Lesson
    1158

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    153

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    Mock Drug Activity Enhances Student Learning About the Challenges of HIV/AIDS Therapy
    While traditional didactic coursework is important for learning about the scientific aspects of HIV/AIDS, it is difficult to convey social aspects of the epidemic. Due to effective drug therapies, an HIV diagnosis is now considered a chronic...

    Courses: MicrobiologyMicrobiology

    Lesson
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    329

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    Chilling in the Cold: Using Thermal Acclimation to Demonstrate Phenotypic Plasticity in Animals
    The lesson plan described here provides students hands-on, scientific experiences that relate to the globally important issue of climate change and its impacts on animals. Students use the scientific method and basic components of experimental...
    Lesson
    18645

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    396

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    A flexible, multi-week approach to plant biology - How will plants respond to higher levels of CO2?
    To help introductory biology students understand how plants will respond to higher levels of CO2, we have created a multi-week module consisting of a series of four related laboratory lessons. These lessons allow students to make connections among...
    Lesson
    2499

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    563

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    Linking Genotype to Phenotype: The Effect of a Mutation in Gibberellic Acid Production on Plant Germination
    Basic concepts in genetics and plant development are often taught in lecture courses without a lab component. This approach provides students with the content knowledge, but fails to make connections to research opportunities and real-world...
    Lesson
    1215

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    151

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    Teaching the Photoelectric Effect Using an Open-Source Interactive Simulation
    The photoelectric effect is one of the fundamental experiments that established the basis of quantum mechanics. Students studying this experiment in modern physics courses struggle to understand what it actually measured and why it is significant....
    Lesson
    6201

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    1041

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    Mapping a Mutation to its Gene: The "Fly Lab" as a Modern Research Experience
    Although genetics is an invaluable part of the undergraduate biology curriculum, it can be intimidating to students as well as instructors: Students must reduce their reliance on memorization and dive deep into quantitative analysis, and...
    Lesson
    669

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    113

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    Evaluating Representation in Science Through a Peer-Reviewed Research Study
    The demographic representation of scientists featured in biology curricular materials do not match that of the undergraduate biology student population or of the U.S. population. In this lesson, we promote awareness of inequity in science through...