CourseSource: Resources

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Sequences and Properties of Gluten Proteins From Different Grains: A Virtual-Friendly Protein Laboratory

The COVID-19 pandemic has forced much university instruction into virtual modes. As a result, many laboratory courses have either dropped content altogether or replaced hands-on activities with simulations and “dry” labs. Our goal was...

Courses: Biochemistry and Molecular Biology Bioinformatics

protein structure and functionProtein sequenceintermolecular forcesBiomacromolecules

Lesson

2050

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517

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A Simple Method for Predicting a Molecule's Biological Properties From Its Polarity

The distinction between very polar and less polar substances is a foundation of biochemistry, cell biology, and physiology; it surfaces in multiple concept inventories and elaborations of biological core concepts. However, in our experience, most...

Courses: Anatomy-Physiology Biochemistry and Molecular Biology Cell Biology Introductory Biology

Diffusionsolubilitycovalent bondshydrophilichydrophobicpartition coefficientplasma membranepolarity

Teaching Tools and Strategies

3635

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1718

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A 360˚ View of COVID-19

In March 2020, institutions underwent a massive transition to distance learning as a result of the COVID-19 pandemic. With so little time to devise new materials to maximize learning in the new virtual environment, instructors devised a variety of...

Courses: Biochemistry and Molecular Biology Bioinformatics Cell Biology Evolution Genetics Immunology Introductory Biology Microbiology Science Process Skills

geneticsImmunologyBiochemistrybioinformaticsmolecular evolutionpublic healthvirusCOVID19

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754

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115

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A Momentum-First Approach to Newton’s Second Law

Students frequently struggle with seeing the connection between forces and motion in introductory physics. This lesson is part of a combined momentum and kinematics unit that first teaches Newton’s second law as a statement of conservation...

Courses: Introductory Physics: Calculus-Based

group workMomentumNewton's Laws

Lesson

1991

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376

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Engaging Undergraduates in Mechanisms of Tubular Reabsorption and Secretion in the Mammalian Kidney

If students fail to see the connections among physiological systems, they can become overwhelmed with the amount of information they need to learn. Some students have particular difficulty with the renal system for this reason. This lesson was...

Courses: Anatomy-Physiology Cell Biology

OsmosisActive transportMass flowRenal reabsorptionRenal secretionTransport across membranes

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4196

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627

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Using Bioinformatics and Molecular Visualization to Develop Student Hypotheses in a Malate Dehydrogenase Oriented CURE

Developing student creativity and ability to develop a testable hypothesis represents a significant challenge in most laboratory courses. This lesson demonstrates how students use facets of molecular evolution and bioinformatics approaches...

Courses: Biochemistry and Molecular Biology Bioinformatics Science Process Skills

bioinformaticsNoncovalent InteractionsEnzyme CatalysisProtein Structure/function

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3882

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209

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Isolation and Functional Analysis of a Pancreatic Enzyme in an Introductory Student Lab

Structure and function are correlated at all levels of biology. This topic is typically addressed early in an undergraduate class in general or molecular biology before students have gained much skill or knowledge in molecular biology. However, an...

Courses: Biochemistry and Molecular Biology Introductory Biology

Protein StructureproteaseEnzymechemical bondscatalysissolubility

Lesson

3775

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415

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Using Open-Source Bioinformatics and Visualization Tools to Explore the Structure and Function of SARS-CoV-2 Spike Protein

The relationship between protein structure and function is a foundational concept in undergraduate biochemistry. We find this theme is best presented with assignments that encourage exploration and analysis. Here, we share a series of four...

Courses: Biochemistry and Molecular Biology Bioinformatics Science Process Skills

bioinformaticsmolecular modelingCOVID19protein structure and functionUCSF ChimeraSARS-CoV-2 spike proteinACE2 receptor

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2717

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242

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Integrating Community Ecology Into the Study of Parasites: Exploring the Effect of Host Behavior on Parasite Transmission Rates

Organismal life cycles are often presented as a set of facts to memorize in undergraduate biology courses. This approach is cognitively demanding for students and fails to convey how central life cycle diversity is in shaping ecological and...

Courses: Ecology Ecology Science Process Skills

statisticsspecies interactionsQuantitative reasoninggraphsCommunity EcologyParasitologyfood webs

Lesson

413

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32

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Osmosis Through the Lens of Sexual Health

Osmosis contributes to a range of biological phenomena, from functioning of nephrons in animals to stomatal opening and closing in plants; yet, scientifically simple ideas about osmosis are common. These ideas limit learners’ comprehension...

Courses: Anatomy-Physiology Cell Biology Introductory Biology Science Process Skills

OsmosisDiffusionsexual healthsocial and cultural embeddedness of scienceinclusive dialogue

Teaching Tools and Strategies

1190

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148

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Lateral Transfer Maps as a Metacognitive Tool in First Year STEM Courses

We introduce the Lateral Transfer Map (LTM), a tool for students to actively and visually explore the transfer of ideas, skills, and concepts across concurrent coursework. The LTM is an extension of a concept map, replacing interconnected concepts...

Courses: Professional Development and Career Planning Science Process Skills

concept mapmetacognitionfirst-year studenttransfer

Lesson

5062

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667

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0

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How Do Kidneys Make Urine From Blood? Qualitative and Quantitative Approaches to Filtration, Secretion, Reabsorption, and Excretion

The function of the kidneys is to help maintain a constant internal environment (homeostasis) by regulating the volume and chemical composition of the blood. This regulation occurs via three fundamental processes: filtration, secretion, and...

Courses: Anatomy-Physiology Introductory Biology

collecting ductexcretionglomerular filtration rate (GFR)nephron tubulereabsorptionrenal corpusclesection

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3927

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454

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Is Earth Currently Undergoing a Sixth Mass Extinction?

The five Phanerozoic mass extinctions were central in shaping biodiversity on Earth today. Due to increasing biodiversity losses, there is debate about whether we are currently undergoing a sixth mass extinction. To help students better understand...

Courses: Ecology Ecology Evolution Introductory Biology

conservationBiodiversityextinctionMass ExtinctionDeep Time

Lesson

2663

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626

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Learning About Protein Localization: A Lesson for Analyzing Figures in a Scientific Publication

In order to function correctly, proteins must be localized to a specific subcellular location. We have designed this lesson to use data from the primary literature to teach students about the mechanisms cells use to direct proteins to the...

Courses: Cell Biology Science Process Skills

colocalizationimmunofluorescenceProtein localizationsignal sequencessubcellular fractionationwestern blotting

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2684

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496

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Harnessing the Power of the Immune System: Influenza Vaccines

Because most people have been infected by and/or immunized against influenza, students should know how the immune system responds to the infection and how vaccines protect against disease. Vaccines have played an instrumental role in disease...

Courses: Biochemistry and Molecular Biology Immunology Science Process Skills

VaccinesInfluenzaImmunizationVaccine efficacy

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Sequences and Properties of Gluten Proteins From Different Grains: A Virtual-Friendly Protein Laboratory

A Simple Method for Predicting a Molecule's Biological Properties From Its Polarity

A 360˚ View of COVID-19

A Momentum-First Approach to Newton’s Second Law

Engaging Undergraduates in Mechanisms of Tubular Reabsorption and Secretion in the Mammalian Kidney

Using Bioinformatics and Molecular Visualization to Develop Student Hypotheses in a Malate Dehydrogenase Oriented CURE

Isolation and Functional Analysis of a Pancreatic Enzyme in an Introductory Student Lab

Using Open-Source Bioinformatics and Visualization Tools to Explore the Structure and Function of SARS-CoV-2 Spike Protein

Integrating Community Ecology Into the Study of Parasites: Exploring the Effect of Host Behavior on Parasite Transmission Rates

Osmosis Through the Lens of Sexual Health

Lateral Transfer Maps as a Metacognitive Tool in First Year STEM Courses

How Do Kidneys Make Urine From Blood? Qualitative and Quantitative Approaches to Filtration, Secretion, Reabsorption, and Excretion

Is Earth Currently Undergoing a Sixth Mass Extinction?

Learning About Protein Localization: A Lesson for Analyzing Figures in a Scientific Publication

Harnessing the Power of the Immune System: Influenza Vaccines

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