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    Discovering Prokaryotic Gene Regulation with Simulations of the trp Operon
    The trp operon exemplifies important biological concepts, including the central dogma of molecular biology, feedback inhibition, and gene regulation. For this reason, regulation of the trp operon is a common theme in introductory biology,...

    Courses: GeneticsGenetics Introductory BiologyIntroductory Biology MicrobiologyMicrobiology

    prokaryotesgene regulationattenuationfeedback inhibitionrepressible operontrp operon
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    358

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    Discovering Cellular Respiration with Computational Modeling and Simulations
    Cellular respiration, a common topic among introductory and cellular biology curricula, is a complex biological process that exemplifies core biological concepts, including systems, pathways and transformation of energy, and structure and function...

    Courses: Introductory BiologyIntroductory Biology

    Cellular MechanismsCellular RespirationFermentation
    Lesson
    2285

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    278

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    Discovering Prokaryotic Gene Regulation by Building and Investigating a Computational Model of the lac Operon
    The ability to construct and reason through a biological system is an important skill to develop in science education. This level of understanding forces students to recognize the interrelatedness of components within a biological process and...

    Courses: Introductory BiologyIntroductory Biology

    prokaryotesgene regulationLac Operoninducible operon
    Lesson
    1222

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    556

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    Understanding Gastric Acid Secretion: An Active Learning Approach
    The human digestive system is a diverse network of cells, tissues, and organs that is regulated by systemic (e.g., nervous and endocrine systems) and local factors (e.g., secretions, pH, and the microbiome). Given the volume of content and the...

    Courses: Anatomy-PhysiologyAnatomy-Physiology

    diseasesignal transductionAcid SecretionAutonomic Nervous SystemEndocrineGastric PhysiologyGPCRHistology of Gastric Pit
    Lesson
    2396

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    279

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    Escape Zoom!: Reviewing Introductory Evolution Content Using an Escape Room Format
    Reviewing and integrating key concepts and learning goals at the end of a biology course can be overwhelming to students and instructors alike. Often end-of-term review sessions in preparation for final exams are heavily based on memorization, and...

    Courses: EcologyEcology EvolutionEvolution GeneticsGenetics

    Evolutionartificial selectionSpeciationextinctionsexual selectionphylogenetic treesmechanisms of evolution
    Lesson
    3499

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    767

    downloads

    2

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    "Got Algae?" A Sorting Game for Introducing the Weird and Wonderful Diversity of Algae
    Algae are a fascinating and diverse organismal group, with global ecological importance, a storied evolutionary history and deep connections to both contemporary and historical human societies. Yet non-experts who teach algal diversity face a lack...

    Courses: EcologyEcology EvolutionEvolution Plant BiologyPlant Biology

    phylogenyBiodiversityphotosynthesisalgaeseaweedmonophyly
    Lesson
    2274

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    351

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    Learning R for Biologists: A Mini Course Grab-Bag for Instructors
    As biology becomes more data driven, teaching students data literacy skills has become central to biology curriculum. Despite a wealth of online resources that teach researchers how to use R, there are few that offer practical laboratory-based...

    Courses: Anatomy-PhysiologyAnatomy-Physiology BioinformaticsBioinformatics EcologyEcology GeneticsGenetics

    Rdata analysisRStudio
    Lesson
    3358

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    1180

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    CRISPR/Cas9 in yeast: a multi-week laboratory exercise for undergraduate students
    Providing undergraduate life-science students with a course-based research experience that utilizes cutting-edge technology, is tractable for students, and is manageable as an instructor is a challenge. Here, I describe a multi-week lesson plan...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology BioinformaticsBioinformatics GeneticsGenetics MicrobiologyMicrobiology Science Process SkillsScience Process Skills

    bioinformaticsPCRphenotypingCRISPR/Cas9gene editingcloningGenotypingRestriction enzyme
    Essay
    1392

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    233

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    2

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    Designing an Asynchronous, Self-Led Aquatic Ecology Field Trip
    Due to the COVID-19 pandemic and increasing need to teach students online, aquatic scientists are looking for ways to give students field experiences virtually. Asynchronous, self-led field trips are emerging as a solution. However, due to the...

    Courses: EcologyEcology

    observationecosystem structureexploration
    Lesson
    3506

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    1299

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    A CRISPR/Cas Guide RNA Design In Silico Activity
    CRISPR biotechnologies inspired by the Clustered Regularly Interspaced Short Palindromic Repeat RNA-guided nuclease adaptive bacterial immune system have revolutionized biology research and become ubiquitous tools for hypothesis and...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology BioinformaticsBioinformatics Cell BiologyCell Biology GeneticsGenetics

    bioinformaticsgene expressiongenetic basis of diseaseCRISPR/Cas9genetic engineeringin silico
    Lesson
    3790

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    1247

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    My Dog IS My Homework: Exploring Canine Genetics to Understand Genotype-Phenotype Relationships
    To facilitate understanding of the fundamental genetic concept of the genotype-phenotype relationship in our introductory biology students, we designed an engaging multi-week series of related lessons about canine genetics in which students...

    Courses: BioinformaticsBioinformatics GeneticsGenetics Introductory BiologyIntroductory Biology Science Process SkillsScience Process Skills

    gel electrophoresissequence analysiscanine geneticsdeoxyribonucleic acid (DNA)dog coat morphologygenotype and phenotypemutationsPolymerase chain reaction (PCR)single nucleotide polymorphism (SNP)
    LessonPlus
    2089

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    174

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    The Power of Place: A Course-Based Undergraduate Research Experience Studying Urban Ecology, Local Apple Trees and Disease Susceptibility
    Course-based Undergraduate Research Experiences (CUREs) offered early in an undergraduate student’s career have the potential to include a greater number and diversity of students than one-on-one mentored research. CUREs that use a...

    Courses: EcologyEcology

    Disease ecologyurban ecologyUrban food forestsUrban heat islandsGenetic resistance
    Lesson
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    139

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    Understanding the Importance of Microtubules in Normal Cell Division: Chemotherapy Connection
    In introductory courses, students learn about microtubules as important structures but may not engage in a hands-on experience to localize microtubules themselves or to learn about their connection to cancer treatment. In this lesson, students...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology Cell BiologyCell Biology GeneticsGenetics

    cancerCell DivisionimmunofluorescenceMicrotubulesAntibodies
    Lesson
    1778

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    130

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    Snail Races: An Inquiry-Based Approach to Learn Invasive Species Ecology
    Inquiry-based lessons allow learning that is hands-on and student-driven, fostering engagement and retention of knowledge in any discipline. Here, we use this learning framework to engage students in exploring the effects of biotic and abiotic...

    Courses: EcologyEcology

    ecologyenvironmentInvasive SpeciesScience CommunicationScientific InquiryDispersal
    Lesson
    1851

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    310

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    Science and Society: Integrating Historical Science Materials Into an Undergraduate Biology Course
    Vision and Change in Undergraduate Biology Education (American Association for the Advancement of Science, 2011) stresses the importance of fostering an understanding of the relationship between science and society. We describe a library-based...

    Courses: MicrobiologyMicrobiology

    infectious diseasevaccinationbacteriavirusesantibiotics