CourseSource: Resources

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What is Speciation, How Does It Occur, and Why Is It Important for Conservation?

Speciation provides a framework for classifying biodiversity on Earth and is a central concept in evolutionary biology. To help undergraduate students learn about speciation, we designed a student-centered lesson that uses active-learning...

Courses: Ecology Ecology Genetics Introductory Biology Science Process Skills

EvolutionconservationGenetic DriftSpeciationNatural SelectionBiological species conceptgene flowMorphological species conceptPhylogenetic species concept

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2389

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279

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0

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Escape Zoom!: Reviewing Introductory Evolution Content Using an Escape Room Format

Reviewing and integrating key concepts and learning goals at the end of a biology course can be overwhelming to students and instructors alike. Often end-of-term review sessions in preparation for final exams are heavily based on memorization, and...

Courses: Ecology Ecology Evolution Genetics

Evolutionartificial selectionSpeciationextinctionsexual selectionphylogenetic treesmechanisms of evolution

Lesson

3785

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1245

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0

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My Dog IS My Homework: Exploring Canine Genetics to Understand Genotype-Phenotype Relationships

To facilitate understanding of the fundamental genetic concept of the genotype-phenotype relationship in our introductory biology students, we designed an engaging multi-week series of related lessons about canine genetics in which students...

Courses: Bioinformatics Genetics Introductory Biology Science Process Skills

gel electrophoresissequence analysiscanine geneticsdeoxyribonucleic acid (DNA)dog coat morphologygenotype and phenotypemutationsPolymerase chain reaction (PCR)single nucleotide polymorphism (SNP)

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2679

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229

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Role of Crop Genetic Diversity on Pathogen Impact: The Tale of Two Pathogens

Introductory genetics courses are part of the core curriculum in many different fields, including plant breeding, animal science, biology, microbiology, and natural resource management. Concepts involving genes, inheritance, evolution, and genome...

Courses: Introductory Biology Plant Biology Science Process Skills

plant pathologygenetic diversityDisease TriangleModes of Reproduction

Lesson

986

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182

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1

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From Cre/LoxP to Fate Maps: Inclusive and Equitable Approaches for Engaging Developmental Biology Students in Experimental Design

Engaging first generation underrepresented minority students in the process of inquiry in developmental biology is important to increase diversity in future graduate STEM education. One important challenge is how we design curricula to foster...

Courses: Developmental Biology

experimental designC. elegansCre/LoxPFate mapheart developmentheart regenerationmousereporter constructzebrafish

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1952

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280

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A CURE-based approach to teaching genomics using mitochondrial genomes

There is an abundance (currently over 1016 DNA bases) of publicly available genetic sequence data and a dearth of trained genomicists to process and interpret it, necessitating more trained bioinformaticians with biological expertise. For...

Courses: Bioinformatics Genetics

proteinsMitochondrial GenomesNuclear GenomesrRNAtRNA

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3406

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284

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Garden Variety Mutations: Using Primary Data to Understand the Central Dogma in Large-Lecture Introductory Biology

The ability to interpret and create an argument from data is a crucial skill for budding scientists, yet one that is seldom practiced in introductory courses. During this argumentation module, students in a large lecture class will work in groups...

Courses: Biochemistry and Molecular Biology Genetics Introductory Biology

mutationtranscriptiongene expressioncentral dogmatranslationgel electrophoresisGenotype/Phenotype

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3159

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404

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Honoring the Complexity of Genetics: Exploring the Role of Genes and the Environment Using Real World Examples

Historically, undergraduate genetics courses have disproportionately focused on the impact of genes on phenotypes, rather than multifactorial concepts which consider how a combination of genes, the environment, and gene-by-environment interactions...

Courses: Evolution Genetics Introductory Biology

genesenvironmentMendelQuantitative traitsMultifactorialGene by environment interactions

Essay

826

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125

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Implementing active learning approaches into an upper-division biology course

In this essay, we present our strategy for implementing active learning strategies into an upper division course on Human Genetics. Our principal goal was to shift from a traditional didactic course design, to one that more clearly placed the...

Courses: Genetics Introductory Biology

human biologyPedigree analysisRare genetic diseases

Lesson

2023

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357

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1

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Interactive Video Vignettes (IVVs) to Help Students Learn Genetics Concepts

Many video resources exist to teach Mendelian genetics, but most consist of passive delivery of information rather than active construction of knowledge by users. We have created two interactive video vignettes (IVVs) that can be used together or...

Courses: Genetics Introductory Biology Science Process Skills

genotypephenotypeallelespedigreedominanceHardy-Weinberg equilibriumInheritance

Lesson

2967

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611

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Using Synthetic Biology and pClone Red for Authentic Research on Promoter Function: Introductory Biology (identifying new promoters)

Students often memorize the definition of a transcriptional promoter but fail to fully understand the critical role promoters play in gene expression. This laboratory lesson allows students to conduct original research by identifying and...

Courses: Genetics Introductory Biology Science Process Skills

bacteriasynthetic biologygene regulationtranscriptionstudent researchcentral dogmacloningpromoterreporter gene/protein

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3502

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1299

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A CRISPR/Cas Guide RNA Design In Silico Activity

CRISPR biotechnologies inspired by the Clustered Regularly Interspaced Short Palindromic Repeat RNA-guided nuclease adaptive bacterial immune system have revolutionized biology research and become ubiquitous tools for hypothesis and...

Courses: Biochemistry and Molecular Biology Bioinformatics Cell Biology Genetics

bioinformaticsgene expressiongenetic basis of diseaseCRISPR/Cas9genetic engineeringin silico

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1880

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636

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A Close-Up Look at PCR

The Polymerase Chain Reaction (PCR) is a fundamental laboratory technique that allows for the amplification of many copies of a desired DNA target sequence. Despite its prevalence, undergraduate students often have poor comprehension about the...

Courses: Biochemistry and Molecular Biology Genetics Introductory Biology Science Process Skills

PCRDNA replication

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3339

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275

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0

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Application of a Bacterial Experimental Evolution System to Visualize and Teach Evolution in Action: A Course-Based Undergraduate Research Experience

Concepts of evolution are typically taught through examples of extremely long timescales, which do not always resonate broadly. Here, we describe a course-based undergraduate research experience tailored for junior and senior undergraduate biology...

Courses: Biochemistry and Molecular Biology Bioinformatics Cell Biology Evolution Genetics Microbiology

EvolutionmutationcompetitionNatural Selectionregulationstructure and functionreproductive fitnessgenotype to phenotypehomologs

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2794

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701

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Teaching Biodiversity with Museum Specimens in an Inquiry-Based Lab

In response to the growth of biology datasets and broad efforts to digitize data, an increasingly important skill for science students is the management and analysis of large datasets. We designed an inquiry-based lab module to introduce students...

Courses: Ecology Ecology Evolution Introductory Biology Science Process Skills

data analysisnatural historyphylogenyBiodiversitymammalsAllen's RuleBergmann's Ruleecogeographymuseum research

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3080

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737

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Using Synthetic Biology and pClone Red for Authentic Research on Promoter Function: Genetics (analyzing mutant promoters)

Students often memorize the definition of a transcriptional promoter but fail to fully understand the critical role promoters play in gene expression. This laboratory lesson allows students to conduct original research by characterizing...

Courses: Genetics Science Process Skills

bacteriasynthetic biologygene regulationtranscriptionstudent researchcentral dogmacloningpromoterreporter gene/protein

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2228

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445

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Metastatic Mastery: A Case and Game-Based Approach to Learning About Cancer Mechanisms

Mechanisms that contribute to the development of cancer are numerous and complicated, though most can be traced to a set of mutations in cell cycle regulatory genes that throw the process of cell division off balance. Communication of these...

Courses: Biochemistry and Molecular Biology Genetics Introductory Biology

mutationcancertranscriptioncell cycletranslationOncogenesTumor-suppressorp53Transcription factor

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1191

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138

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Understanding the Importance of Microtubules in Normal Cell Division: Chemotherapy Connection

In introductory courses, students learn about microtubules as important structures but may not engage in a hands-on experience to localize microtubules themselves or to learn about their connection to cancer treatment. In this lesson, students...

Courses: Biochemistry and Molecular Biology Cell Biology Genetics

cancerCell DivisionimmunofluorescenceMicrotubulesAntibodies

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1648

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317

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Differential Gene Expression during Xenopus laevis Development

In Developmental Biology classes, students are challenged with understanding how differential gene expression guides embryonic development. It can be difficult for students to realize that genes need to be turned on or off at the right time and...

Courses: Developmental Biology

gene expressionXenopusearly developmentembryofertilizationin situ hybridization

Lesson

3615

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953

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Life Is Just a Game: An Active Learning Activity to Teach Life History Evolution

A novel activity was designed to introduce students to the concepts of natural selection and life history using an active-learning, constructivist format. It consisted of two parts: 1) a brief introduction to the basic mechanism of natural...

Courses: Ecology Ecology Evolution

Evolutionlife historytrade-offsdiversityNatural Selection

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What is Speciation, How Does It Occur, and Why Is It Important for Conservation?

Escape Zoom!: Reviewing Introductory Evolution Content Using an Escape Room Format

My Dog IS My Homework: Exploring Canine Genetics to Understand Genotype-Phenotype Relationships

Role of Crop Genetic Diversity on Pathogen Impact: The Tale of Two Pathogens

From Cre/LoxP to Fate Maps: Inclusive and Equitable Approaches for Engaging Developmental Biology Students in Experimental Design

A CURE-based approach to teaching genomics using mitochondrial genomes

Garden Variety Mutations: Using Primary Data to Understand the Central Dogma in Large-Lecture Introductory Biology

Honoring the Complexity of Genetics: Exploring the Role of Genes and the Environment Using Real World Examples

Implementing active learning approaches into an upper-division biology course

Interactive Video Vignettes (IVVs) to Help Students Learn Genetics Concepts

Using Synthetic Biology and pClone Red for Authentic Research on Promoter Function: Introductory Biology (identifying new promoters)

A CRISPR/Cas Guide RNA Design In Silico Activity

A Close-Up Look at PCR

Application of a Bacterial Experimental Evolution System to Visualize and Teach Evolution in Action: A Course-Based Undergraduate Research Experience

Teaching Biodiversity with Museum Specimens in an Inquiry-Based Lab

Using Synthetic Biology and pClone Red for Authentic Research on Promoter Function: Genetics (analyzing mutant promoters)

Metastatic Mastery: A Case and Game-Based Approach to Learning About Cancer Mechanisms

Understanding the Importance of Microtubules in Normal Cell Division: Chemotherapy Connection

Differential Gene Expression during Xenopus laevis Development

Life Is Just a Game: An Active Learning Activity to Teach Life History Evolution

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