CourseSource: Resources

Teaching Tools and Strategies

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Walkabout: An Easy to Use, Experiential Learning Activity for Applying Abstract Concepts to the Real-World

Students can have difficulty recognizing examples of course concepts in the real-world. They particularly struggle with phenomena that are ambiguously defined, have mimics, or are hard to distinguish from other phenomena. Students can better...

Courses: Ecology Ecology Science Process Skills

data gatheringgreen technologyobservations

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612

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Using Synthetic Biology and pClone Red for Authentic Research on Promoter Function: Introductory Biology (identifying new promoters)

Students often memorize the definition of a transcriptional promoter but fail to fully understand the critical role promoters play in gene expression. This laboratory lesson allows students to conduct original research by identifying and...

Courses: Genetics Introductory Biology Science Process Skills

bacteriasynthetic biologygene regulationtranscriptionstudent researchcentral dogmacloningpromoterreporter gene/protein

Teaching Tools and Strategies

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307

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Sanger Sequencing by Hand: Using Paper Clips to Demonstrate Chain Termination

Sanger sequencing is commonly taught with a hands-on approach. Sanger sequencing involves chain termination by dideoxynucleotides, because they are missing the oxygen on the 3’ carbon atom, which is required for the addition of subsequent...

Courses: Genetics

nucleotidessequencingDNAgel electrophoresisChain Termination

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Using Synthetic Biology and pClone Red for Authentic Research on Promoter Function: Genetics (analyzing mutant promoters)

Students often memorize the definition of a transcriptional promoter but fail to fully understand the critical role promoters play in gene expression. This laboratory lesson allows students to conduct original research by characterizing...

Courses: Genetics Science Process Skills

bacteriasynthetic biologygene regulationtranscriptionstudent researchcentral dogmacloningpromoterreporter gene/protein

Lesson

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744

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0

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Green Design: How do Leaf Structures Optimize Photosynthesis and Promote Survival?

One of the major learning objectives established by the American Society of Plant Biologists and the Botanical Society of America has students answer the question: How do plant structures enable life functions? This lesson helps students answer...

Courses: Introductory Biology Plant Biology

photosynthesisepidermal layerleaf anatomymesophyllpalisade parenchymaplant anatomyplant structure functionspongy parenchymaStomata

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CRISPR/Cas9 in yeast: a multi-week laboratory exercise for undergraduate students

Providing undergraduate life-science students with a course-based research experience that utilizes cutting-edge technology, is tractable for students, and is manageable as an instructor is a challenge. Here, I describe a multi-week lesson plan...

Courses: Biochemistry and Molecular Biology Bioinformatics Genetics Microbiology Science Process Skills

bioinformaticsPCRphenotypingCRISPR/Cas9gene editingcloningGenotypingRestriction enzyme

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767

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"Got Algae?" A Sorting Game for Introducing the Weird and Wonderful Diversity of Algae

Algae are a fascinating and diverse organismal group, with global ecological importance, a storied evolutionary history and deep connections to both contemporary and historical human societies. Yet non-experts who teach algal diversity face a lack...

Courses: Ecology Ecology Evolution Plant Biology

phylogenyBiodiversityphotosynthesisalgaeseaweedmonophyly

Lesson

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474

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Go Extinct! An Award-Winning Evolution Game That Teaches Tree-Thinking as Students Pursue the Winning Strategy

Evolutionary trees communicate both the diversity and unity of life, a central and important scientific concept, as highlighted by the Vision and Change undergraduate biology education movement. Evolutionary trees and cladograms are diagrams...

Courses: Evolution

phylogeneticsnatural historyBiodiversitycladogramCommon ancestorEvolutionary treeLand vertebratesMonophyletic cladeTetrapods

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3165

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458

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0

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Small Organisms with Big Consequences: Understanding the Microbial World Around Us

Creating a hands-on lab that conveys important information while simultaneously allowing for student autonomy can be difficult. This is particularly true for the field of microbiology, in which labs often rely on “recipe-style”...

Courses: Introductory Biology Microbiology Science Process Skills

disease transmissionmicrobiologymicrobiomeliterature reviewPeer reviewPathogensHealth and WellnessThe Scientific Method

Teaching Tools and Strategies

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142

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An Open Source, Collaborative Electronic Notebook for Undergraduate Laboratory Classes

To overcome many of the limitations of the paper laboratory notebook (PLN), we developed an electronic laboratory notebook (e-LN) for the Dynamic Genome course at the University of California. The Dynamic Genome course is an authentic research...

Courses: Science Process Skills

data collectionData annotationNotebook Skills

Lesson

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322

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Marsh Madness: Using Video Games and a Case Study to Explore Food Webs and Ecosystem Services in Carpinteria Salt Marsh Reserve

As the complexity and interconnectedness of our world increases, we are continually expected to be capable of complex, non-linear thinking in order to successfully tackle and solve the challenges we face in the 21st century. Tackling these...

Courses: Ecology Ecology

food webssystems thinkingGame Based LearningEcosystem Servicessocio-ecological networks

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3401

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Using CRISPR-Cas9 to teach the fundamentals of molecular biology and experimental design

One of the challenges of inquiry-based research experiences is balancing the instruction on skills and techniques with data generation and analysis. This is especially true in technique heavy disciplines such as molecular biology, where emphasis...

Courses: Biochemistry and Molecular Biology

experimental designcrisprmolecular technique

Essay

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Designing an Asynchronous, Self-Led Aquatic Ecology Field Trip

Due to the COVID-19 pandemic and increasing need to teach students online, aquatic scientists are looking for ways to give students field experiences virtually. Asynchronous, self-led field trips are emerging as a solution. However, due to the...

Courses: Ecology Ecology

observationecosystem structureexploration

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168

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A Rapid Genetic Screen Using Wisconsin Fast Plants^®: A Hands-On Approach to Inheritance of de novo Mutations

Some concepts in genetics, such as genetic screens, are complex for students to visualize in a classroom and can be cumbersome to undertake in the laboratory. Typically, very large populations are needed, which can be addressed by using...

Courses: Genetics Plant Biology

mutationInheritancegermlinesomaplant lifecycle

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498

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Does Organelle Shape Matter?: Exploring Patterns in Cell Shape and Structure with High-Throughput (HT) Imaging

Organelle structure has been studied and visualized for decades; however, publicly available databases that use improved high-throughput microscopy of gene-edited cell lines have recently revolutionized the amount and quality of information now...

Courses: Biochemistry and Molecular Biology Bioinformatics Cell Biology Genetics Science Process Skills

modelingcase studymicroscopystructureOrganellesHigh-throughput (HT)Endoplasmic Reticulum (ER)Fluorescent microscopyHuman Cell Biology

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Is Earth Currently Undergoing a Sixth Mass Extinction?

The five Phanerozoic mass extinctions were central in shaping biodiversity on Earth today. Due to increasing biodiversity losses, there is debate about whether we are currently undergoing a sixth mass extinction. To help students better understand...

Courses: Ecology Ecology Evolution Introductory Biology

conservationBiodiversityextinctionMass ExtinctionDeep Time

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Integrating Manipulatives and Animations to Visualize Holliday Junctions

The complex molecular architecture of Holliday junctions is often challenging for undergraduate biochemistry students to conceptualize. In particular, they have difficulty translating from two-dimensional, linear representations shown in textbooks...

Courses: Biochemistry and Molecular Biology Genetics

dna structureDNA damageDNA recombinationGene crossoverHolliday junction

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281

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Escape Zoom!: Reviewing Introductory Evolution Content Using an Escape Room Format

Reviewing and integrating key concepts and learning goals at the end of a biology course can be overwhelming to students and instructors alike. Often end-of-term review sessions in preparation for final exams are heavily based on memorization, and...

Courses: Ecology Ecology Evolution Genetics

Evolutionartificial selectionSpeciationextinctionsexual selectionphylogenetic treesmechanisms of evolution

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An undergraduate bioinformatics curriculum that teaches eukaryotic gene structure

Gene structure, transcription, translation, and alternative splicing are challenging concepts for many undergraduates studying biology. These topics are typically covered in a traditional lecture environment, but students often fail to master and...

Courses: Biochemistry and Molecular Biology Bioinformatics Genetics

bioinformaticsGenome BrowsergenomicsRNAseqsplicingComputer ModelGene Structure

LessonPlus

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Keep It Shrimple: An Adaptable Student-Driven Research Project for the Introductory Biology Laboratory

A challenge in introductory biology laboratory courses is to provide students with authentic, engaging research opportunities that allow them to take ownership of their experiments. We present a nine-week introductory biology module that allows...

Courses: Introductory Biology Science Process Skills

hypothesis testingexperimental designanimal behaviorbrine shrimp

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Walkabout: An Easy to Use, Experiential Learning Activity for Applying Abstract Concepts to the Real-World

Using Synthetic Biology and pClone Red for Authentic Research on Promoter Function: Introductory Biology (identifying new promoters)

Sanger Sequencing by Hand: Using Paper Clips to Demonstrate Chain Termination

Using Synthetic Biology and pClone Red for Authentic Research on Promoter Function: Genetics (analyzing mutant promoters)

Green Design: How do Leaf Structures Optimize Photosynthesis and Promote Survival?

CRISPR/Cas9 in yeast: a multi-week laboratory exercise for undergraduate students

"Got Algae?" A Sorting Game for Introducing the Weird and Wonderful Diversity of Algae

Go Extinct! An Award-Winning Evolution Game That Teaches Tree-Thinking as Students Pursue the Winning Strategy

Small Organisms with Big Consequences: Understanding the Microbial World Around Us

An Open Source, Collaborative Electronic Notebook for Undergraduate Laboratory Classes

Marsh Madness: Using Video Games and a Case Study to Explore Food Webs and Ecosystem Services in Carpinteria Salt Marsh Reserve

Using CRISPR-Cas9 to teach the fundamentals of molecular biology and experimental design

Designing an Asynchronous, Self-Led Aquatic Ecology Field Trip

A Rapid Genetic Screen Using Wisconsin Fast Plants^®: A Hands-On Approach to Inheritance of de novo Mutations

Does Organelle Shape Matter?: Exploring Patterns in Cell Shape and Structure with High-Throughput (HT) Imaging

Is Earth Currently Undergoing a Sixth Mass Extinction?

Integrating Manipulatives and Animations to Visualize Holliday Junctions

Escape Zoom!: Reviewing Introductory Evolution Content Using an Escape Room Format

An undergraduate bioinformatics curriculum that teaches eukaryotic gene structure

Keep It Shrimple: An Adaptable Student-Driven Research Project for the Introductory Biology Laboratory

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