CourseSource: Resources

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Quantifying Uncertainty and Distinguishing Data Sets in Introductory Physics

Physics labs are moving increasingly to open-ended experiments where students develop experimental physics skills, rather than verify textbook physics concepts. This sequence of activities sets the stage for this new kind of lab early in the...

Courses: Introductory Physics: Calculus-Based

statisticsMeasurementlaboratoryuncertaintypendulumexperimental skills

Lesson

2043

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586

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BioVEDA Curriculum: An Approach to Link Conceptual and Quantitative Understanding of Variation During Experimental Design and Data Analysis

When performing a biological investigation, experts constantly cycle between conceptual and quantitative modes of thinking, integrating their understanding in both worlds to make decisions about their work. This cycling and mixing of conceptual...

Courses: Science Process Skills

statisticssample sizeBiological variation

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1479

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Using Images of Foraging Leaf-Cutter Ants to Teach Linear Regression

This lesson offers students a realistic, open-inquiry research experience, even when lab or field research is not possible. We first introduce students to leaf-cutter ants and how they forage. Then we provide images and videos of foraging...

Courses: Ecology Ecology Introductory Biology Science Process Skills

linear regressionexperimental designPlant-insect interactionsSymbiosisForaging behavior

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3682

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270

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Bringing Pasteur Back to Life: Studying the Biochemistry of Yeast Fermentation Through Discussion Groups and an At-Home Lab

This hands-on, student-centered biochemistry lesson introduces beginner biochemistry students to the techniques of effectively reading and discussing primary literature, identifying fundamental biological concepts, and applying that knowledge to...

Courses: Biochemistry and Molecular Biology Microbiology Science Process Skills

primary literatureexperimentationyeastMetabolismFermentationRespirationequilibrium

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5092

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347

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Learning to Pipet Correctly by Pipetting Incorrectly?

Beginning undergraduate students in biology need basic laboratory, data analysis, and science process skills to pursue more complex questions in course-based undergraduate research experiences (CUREs). To this end, we designed an introductory...

Courses: Introductory Biology Science Process Skills

statisticslaboratorypipetting

Lesson

3685

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200

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Three Research-Based Quantitative Reasoning Modules for Introductory Organismal Biology Laboratories

We have designed three laboratory modules for an introductory organismal biology course with an emphasis on quantitative reasoning and data analysis skills. Module 1 tests for dimorphism in crayfish chelae using a paired statistical design. Module...

Courses: Introductory Biology Science Process Skills

allometryplantsAnatomytranspirationdimorphisminvertebrate biologyarthropodsplatyhelminths

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2584

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202

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A Laboratory Module That Explores RNA Interference and Codon Optimization Through Fluorescence Microscopy Using Caenorhabditis elegans

Scientific research experiences are beneficial to students allowing them to gain laboratory and problem-solving skills, as well as foundational research skills in a team-based setting. We designed a laboratory module to provide a guided research...

Courses: Bioinformatics Cell Biology Developmental Biology Genetics Science Process Skills

microscopyC. elegansquantitative analysisinquiry-based learninggene expressionRNA interferenceCodon UsageLaboratory Module

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2325

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436

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Dynamic Daphnia: An inquiry-based research experience in ecology that teaches the scientific process to first-year biologists

This authentic research experience lesson teaches the core concept of systems and the competencies of quantitative reasoning, communication, and the ability to apply science. The research is student driven, the results are unknown, and the...

Courses: Ecology Ecology Introductory Biology Science Process Skills

statisticsecologyscientific methodexperimental designAbiotic and Biotic FactorsDependent and Independent Variables

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3877

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208

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Isolation and Functional Analysis of a Pancreatic Enzyme in an Introductory Student Lab

Structure and function are correlated at all levels of biology. This topic is typically addressed early in an undergraduate class in general or molecular biology before students have gained much skill or knowledge in molecular biology. However, an...

Courses: Biochemistry and Molecular Biology Introductory Biology

Protein StructureproteaseEnzymechemical bondscatalysissolubility

Teaching Tools and Strategies

3634

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1718

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A 360˚ View of COVID-19

In March 2020, institutions underwent a massive transition to distance learning as a result of the COVID-19 pandemic. With so little time to devise new materials to maximize learning in the new virtual environment, instructors devised a variety of...

Courses: Biochemistry and Molecular Biology Bioinformatics Cell Biology Evolution Genetics Immunology Introductory Biology Microbiology Science Process Skills

geneticsImmunologyBiochemistrybioinformaticsmolecular evolutionpublic healthvirusCOVID19

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1707

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466

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Ain't No Mountain Pine Enough: A Case Study of How Mountain Pine Beetles are Affecting Ecosystem Processes

This case study engages students in generating hypotheses and predictions, analyzing and interpreting data, critically evaluating contrasting results in science, and thinking about feedbacks between biota and abiotic ecosystem dynamics. To address...

Courses: Ecology Ecology

population biologycarbon cyclingSpecies-habitat interactions

Lesson

2793

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700

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Teaching Biodiversity with Museum Specimens in an Inquiry-Based Lab

In response to the growth of biology datasets and broad efforts to digitize data, an increasingly important skill for science students is the management and analysis of large datasets. We designed an inquiry-based lab module to introduce students...

Courses: Ecology Ecology Evolution Introductory Biology Science Process Skills

data analysisnatural historyphylogenyBiodiversitymammalsAllen's RuleBergmann's Ruleecogeographymuseum research

Lesson

3339

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275

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Application of a Bacterial Experimental Evolution System to Visualize and Teach Evolution in Action: A Course-Based Undergraduate Research Experience

Concepts of evolution are typically taught through examples of extremely long timescales, which do not always resonate broadly. Here, we describe a course-based undergraduate research experience tailored for junior and senior undergraduate biology...

Courses: Biochemistry and Molecular Biology Bioinformatics Cell Biology Evolution Genetics Microbiology

EvolutionmutationcompetitionNatural Selectionregulationstructure and functionreproductive fitnessgenotype to phenotypehomologs

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3132

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501

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Targeting Misconceptions in the Central Dogma by Examining Viral Infection

Understanding the central dogma and how changes in gene expression can impact cell function requires integration of several topics in molecular biology. Students often do not make the necessary connections between DNA structure, transcription,...

Courses: Genetics Introductory Biology

datatranscriptionvirustranslationprotein functionmembrane transportPredictions

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Design Your Own Flow Cytometry Experiment: A Four-Week Inquiry Laboratory

Due to its importance to the field, flow cytometry should be one of the hallmark methods a student learns in the lab portion of an undergraduate immunology course. Flow cytometry is a classic lab technique utilized within immunology and molecular...

Courses: Immunology

Immunologyexperimental designFlow cytometryMice

Lesson

1996

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Fly Exercise: A Simple Experiment to Test the Physiological Effects of Exercise on a Model Organism

Model organisms are commonly used to study and experimentally explore biological processes in ways that are technically or ethically not possible in humans. For this reason, model organisms are an essential component of scientific research and...

Courses: Biochemistry and Molecular Biology Introductory Biology Science Process Skills

exerciseenzyme kineticsmetabolite concentrationmodel speciesphysical activity

Lesson

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CRISPR/Cas9 in yeast: a multi-week laboratory exercise for undergraduate students

Providing undergraduate life-science students with a course-based research experience that utilizes cutting-edge technology, is tractable for students, and is manageable as an instructor is a challenge. Here, I describe a multi-week lesson plan...

Courses: Biochemistry and Molecular Biology Bioinformatics Genetics Microbiology Science Process Skills

bioinformaticsPCRphenotypingCRISPR/Cas9gene editingcloningGenotypingRestriction enzyme

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Investigating Cell Signaling with Gene Expression Datasets

Modern molecular biology is a data- and computationally-intensive field with few instructional resources for introducing undergraduate students to the requisite skills and techniques for analyzing large data sets. This Lesson helps students: (i)...

Courses: Biochemistry and Molecular Biology Cell Biology

genomicstranscriptionsignaling

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1751

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Student-Driven Design-and-Improve Modules to Explore the Effect of Plant Bioactive Compounds in Three Model Organisms

Engaging and supporting introductory level students in authentic research experiences during required coursework is challenging. Plant bioactive compounds attract students' natural curiosity as they are found in many familiar items such as...

Courses: Introductory Biology Science Process Skills

statisticsLabCUREInquiryresearch skillscaterpillardaphniadrugsscience process

Lesson

1248

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Defining Life: Exploring Creativity, Scientific Discovery, and Biology Core Concepts in a Disciplinary First-Year Seminar

This unit, Defining Life, engages students in thinking like scientists, applying creativity to science, and learning biology core concepts as they explore the defining characteristics of life. This unit provides an example of a curriculum designed...

Courses: Biochemistry and Molecular Biology Cell Biology Evolution Genetics Introductory Biology Microbiology Science Process Skills

Evolutionbiologycellprocess of science

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Quantifying Uncertainty and Distinguishing Data Sets in Introductory Physics

BioVEDA Curriculum: An Approach to Link Conceptual and Quantitative Understanding of Variation During Experimental Design and Data Analysis

Using Images of Foraging Leaf-Cutter Ants to Teach Linear Regression

Bringing Pasteur Back to Life: Studying the Biochemistry of Yeast Fermentation Through Discussion Groups and an At-Home Lab

Learning to Pipet Correctly by Pipetting Incorrectly?

Three Research-Based Quantitative Reasoning Modules for Introductory Organismal Biology Laboratories

A Laboratory Module That Explores RNA Interference and Codon Optimization Through Fluorescence Microscopy Using Caenorhabditis elegans

Dynamic Daphnia: An inquiry-based research experience in ecology that teaches the scientific process to first-year biologists

Isolation and Functional Analysis of a Pancreatic Enzyme in an Introductory Student Lab

A 360˚ View of COVID-19

Ain't No Mountain Pine Enough: A Case Study of How Mountain Pine Beetles are Affecting Ecosystem Processes

Teaching Biodiversity with Museum Specimens in an Inquiry-Based Lab

Application of a Bacterial Experimental Evolution System to Visualize and Teach Evolution in Action: A Course-Based Undergraduate Research Experience

Targeting Misconceptions in the Central Dogma by Examining Viral Infection

Design Your Own Flow Cytometry Experiment: A Four-Week Inquiry Laboratory

Fly Exercise: A Simple Experiment to Test the Physiological Effects of Exercise on a Model Organism

CRISPR/Cas9 in yeast: a multi-week laboratory exercise for undergraduate students

Investigating Cell Signaling with Gene Expression Datasets

Student-Driven Design-and-Improve Modules to Explore the Effect of Plant Bioactive Compounds in Three Model Organisms

Defining Life: Exploring Creativity, Scientific Discovery, and Biology Core Concepts in a Disciplinary First-Year Seminar

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