CourseSource: Resources

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Using Synthetic Biology and pClone Red for Authentic Research on Promoter Function: Genetics (analyzing mutant promoters)

Students often memorize the definition of a transcriptional promoter but fail to fully understand the critical role promoters play in gene expression. This laboratory lesson allows students to conduct original research by characterizing...

Courses: Genetics Science Process Skills

bacteriasynthetic biologygene regulationtranscriptionstudent researchcentral dogmacloningpromoterreporter gene/protein

Essay

826

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125

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Implementing active learning approaches into an upper-division biology course

In this essay, we present our strategy for implementing active learning strategies into an upper division course on Human Genetics. Our principal goal was to shift from a traditional didactic course design, to one that more clearly placed the...

Courses: Genetics Introductory Biology

human biologyPedigree analysisRare genetic diseases

Teaching Tools and Strategies

1067

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140

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0

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Casting a Wide Net via Case Studies: Educating across the undergraduate to medical school continuum in the biological sciences

This article seeks to help bridge undergraduate and medical educators by describing shared educational goals and strategies, highlighting resources relevant for both groups, and exemplifying shared interests through a demonstration resource. Both...

Courses: Genetics

genetic testingdirect-to-consumer genetic testinginformed consentprenatal screeningsecondary findingswhole genome sequencing

Teaching Tools and Strategies

1160

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346

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Fostering Student to Student Collaboration Across Institutions in a Protein Centric CURE

Collaboration is an essential component of research because it allows scientists to share expertise and tackle difficult scientific questions. While many undergraduate science courses include inquiry-based or authentic research projects,...

Courses: Biochemistry and Molecular Biology Genetics Introductory Biology Professional Development and Career Planning Science Process Skills

communicationBiochemistrycollaborationCUREhypothesisStudent to StudentInter institutionalProtein CentricAssignments

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1876

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348

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0

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Engaging Students in Pharmacogenetics: Patient Case Studies Using the PharmGKB Website

Cytochrome P450 (CYP) enzymes are important regulators of drug efficacy and toxicity. Genetic variation in CYP isoforms can impact how well patients respond to medications or experience unwanted toxicities. PharmGKB is an online pharmacogenomics...

Courses: Genetics Toxicology

toxicologyPharmacologydrug metabolismpharmacodynamicspharmacogenetics

Lesson

2559

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640

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0

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Follow the Sulfur: Using Yeast Mutants to Study a Metabolic Pathway

Students are frequently overwhelmed by the complexity of metabolic pathways and they think they have "learned" the pathway when they have memorized the individual reactions. This laboratory lesson helps students to understand the...

Courses: Biochemistry and Molecular Biology Genetics Introductory Biology Microbiology Science Process Skills

SelectionyeastMetabolismcysteinemediamethioninemutantPathwaysulfur

Teaching Tools and Strategies

3635

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1718

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A 360˚ View of COVID-19

In March 2020, institutions underwent a massive transition to distance learning as a result of the COVID-19 pandemic. With so little time to devise new materials to maximize learning in the new virtual environment, instructors devised a variety of...

Courses: Biochemistry and Molecular Biology Bioinformatics Cell Biology Evolution Genetics Immunology Introductory Biology Microbiology Science Process Skills

geneticsImmunologyBiochemistrybioinformaticsmolecular evolutionpublic healthvirusCOVID19

Lesson

2966

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611

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Using Synthetic Biology and pClone Red for Authentic Research on Promoter Function: Introductory Biology (identifying new promoters)

Students often memorize the definition of a transcriptional promoter but fail to fully understand the critical role promoters play in gene expression. This laboratory lesson allows students to conduct original research by identifying and...

Courses: Genetics Introductory Biology Science Process Skills

bacteriasynthetic biologygene regulationtranscriptionstudent researchcentral dogmacloningpromoterreporter gene/protein

Lesson

5897

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759

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0

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Animal Behaviour Case Study Lessons in Communication, Migration, and Parental Care Using the Jigsaw Approach

Animal behaviour courses integrate concepts across biological disciplines and are particularly well suited for collaborative, student-focused teaching strategies. Case Studies can positively impact students by...

Courses: Ecology Ecology Evolution Science Process Skills

case studycommunicationprimary literatureanimal behaviorjigsawParental CaremigrationAnimal BehaviourProximate mechanisms

Teaching Tools and Strategies

2788

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271

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0

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The Pipeline CURE: An Iterative Approach to Introduce All Students to Research Throughout a Biology Curriculum

Participation in research provides personal and professional benefits for undergraduates. However, some students face institutional barriers that prevent their entry into research, particularly those from underrepresented groups who may stand to...

Courses: Developmental Biology Genetics Introductory Biology Science Process Skills

epigeneticsundergraduate researchmendelian inheritanceSelf-EfficacyCUREsnature of scienceResiliencecurriculum strategiesreprogramming

Lesson

3339

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275

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0

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Application of a Bacterial Experimental Evolution System to Visualize and Teach Evolution in Action: A Course-Based Undergraduate Research Experience

Concepts of evolution are typically taught through examples of extremely long timescales, which do not always resonate broadly. Here, we describe a course-based undergraduate research experience tailored for junior and senior undergraduate biology...

Courses: Biochemistry and Molecular Biology Bioinformatics Cell Biology Evolution Genetics Microbiology

EvolutionmutationcompetitionNatural Selectionregulationstructure and functionreproductive fitnessgenotype to phenotypehomologs

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2388

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279

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Escape Zoom!: Reviewing Introductory Evolution Content Using an Escape Room Format

Reviewing and integrating key concepts and learning goals at the end of a biology course can be overwhelming to students and instructors alike. Often end-of-term review sessions in preparation for final exams are heavily based on memorization, and...

Courses: Ecology Ecology Evolution Genetics

Evolutionartificial selectionSpeciationextinctionsexual selectionphylogenetic treesmechanisms of evolution

Teaching Tools and Strategies

750

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66

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0

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A Journal Club Project to Promote Interpreting and Presenting Information From the Primary Scientific Literature

Many undergraduate students receive little guidance on how to critically read, interpret data within, or present information from the primary scientific literature before they begin senior independent research experiences or enter professional or...

Courses: Developmental Biology Neurobiology

primary literaturejournal clubScience CommunicationfeedbackPeer reviewgroup workOral presentationProcess skillsPeer evaluationDevelopmental neurobiology

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1563

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300

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Using QIIME to Interpret Environmental Microbial Communities in an Upper Level Metagenomics Course

Metagenomics is rapidly evolving due to advances in sequencing technologies and bioinformatics, but without proper training to interpret these datasets, student understanding remains limited. Aimed at undergraduate juniors and seniors and graduate...

Courses: Biochemistry and Molecular Biology Bioinformatics Ecology Ecology Microbiology Science Process Skills

microbiome

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553

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Meiosis Remodeled: Inclusion of New Parts to Poppit Bead Models Enhances Understanding of Meiosis

A long-standing tradition uses strings of poppit beads of different colors to model meiosis, especially to show how segments of paired homologous chromosomes are recombined. Our use of orthodontic latex bands to model cohesion of sister...

Courses: Cell Biology Genetics Introductory Biology

meiosischiasma formationchromosome recombination

Teaching Tools and Strategies

5656

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819

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Science “Fails”: A Bank of Historical Examples for Learning From Failure in Science

Learning from failure is critically important to the processes of scientific inquiry, discovery, and invention. However, students are not routinely taught how to reflect on, learn from, and ultimately embrace failure, and relatively few curricular...

Courses: Introductory Physics: Calculus-Based Introductory Biology Professional Development and Career Planning Science Process Skills

metacognitionScience process skillsLearning from failurepower and privilegestudent wellbeing

Lesson

3549

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263

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SEAS CURE: Exploring Coral Biology Across Scales

Complex biological concepts (like symbiosis and coral biology) that span multiple scales and cross disciplinary boundaries are often difficult for students to understand. This complexity is compounded by the challenges inherent to teaching and...

Courses: Anatomy-Physiology Cell Biology Ecology Ecology Introductory Biology Science Process Skills

microscopyAnatomySymbiosisMetabolismbleachinginvertebratedinoflagellate

Teaching Tools and Strategies

1213

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131

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Undergraduates Learn Evolution Through Teaching Kindergartners About Blind Mexican Cavefish

The development and implementation of a scientific outreach activity comes with a number of challenges. A successful outreach event must match the sophistication of content to the audience, be engaging, expand the knowledge base for participants,...

Courses: Ecology Ecology Evolution Genetics Introductory Biology

Evolutionecologymorphologysensory biologycave biologycomparative biologyenvironmental differencesregressive lossstructure and function

Lesson

680

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534

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Cross-Course Public Health Project on Infectious Disease

The need for collaborative, public health education has never been more important. Students increasingly require necessary skills in effectively communicating critical information to the general public and in working strategically in...

Courses: Microbiology

infectionpublic healthVaccinespathogenesisantibiotics

Lesson

4204

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286

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Analysis of Microbiomes Using Free Web-Based Tools in Online and In-Person Undergraduate Science Courses

Our understanding of microbiomes, or the collection of microorganisms and their genes in a given environment, has been revolutionized by technological and computational advances. However, many undergraduate students do not get hands-on experiences...

Courses: Bioinformatics Ecology Ecology Microbiology

microbiomeDNA SubwayCyVerseCourse based undergraduate researchQIIME2ranacapa

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Using Synthetic Biology and pClone Red for Authentic Research on Promoter Function: Genetics (analyzing mutant promoters)

Implementing active learning approaches into an upper-division biology course

Casting a Wide Net via Case Studies: Educating across the undergraduate to medical school continuum in the biological sciences

Fostering Student to Student Collaboration Across Institutions in a Protein Centric CURE

Engaging Students in Pharmacogenetics: Patient Case Studies Using the PharmGKB Website

Follow the Sulfur: Using Yeast Mutants to Study a Metabolic Pathway

A 360˚ View of COVID-19

Using Synthetic Biology and pClone Red for Authentic Research on Promoter Function: Introductory Biology (identifying new promoters)

Animal Behaviour Case Study Lessons in Communication, Migration, and Parental Care Using the Jigsaw Approach

The Pipeline CURE: An Iterative Approach to Introduce All Students to Research Throughout a Biology Curriculum

Application of a Bacterial Experimental Evolution System to Visualize and Teach Evolution in Action: A Course-Based Undergraduate Research Experience

Escape Zoom!: Reviewing Introductory Evolution Content Using an Escape Room Format

A Journal Club Project to Promote Interpreting and Presenting Information From the Primary Scientific Literature

Using QIIME to Interpret Environmental Microbial Communities in an Upper Level Metagenomics Course

Meiosis Remodeled: Inclusion of New Parts to Poppit Bead Models Enhances Understanding of Meiosis

Science “Fails”: A Bank of Historical Examples for Learning From Failure in Science

SEAS CURE: Exploring Coral Biology Across Scales

Undergraduates Learn Evolution Through Teaching Kindergartners About Blind Mexican Cavefish

Cross-Course Public Health Project on Infectious Disease

Analysis of Microbiomes Using Free Web-Based Tools in Online and In-Person Undergraduate Science Courses

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