CourseSource: Resources

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A Short Laboratory Module to Help Infuse Metacognition during an Introductory Course-based Research Experience

A core competency identified in Vision and Change for undergraduate biology students is the Ability to Apply the Process of Science. Here, we describe a three-week laboratory module for students in an Introductory Cell and Molecular Biology...

Courses: Science Process Skills

metacognitiongene expressionScientific ProcessExperimenal DesignHypothesis Generationmodel organisms

Teaching Tools and Strategies

2495

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321

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A How to Guide and Template for Designing a Puzzle Based Escape Room Game

Educational games are one active and effective way of engaging students with material while also providing additional motivation to tackle challenging concepts. A particularly popular game concept is the escape room, where students need to work in...

Courses: Biochemistry and Molecular Biology Bioinformatics Ecology Ecology Evolution Genetics Science Process Skills

Problem SolvingCollaborative WorkCorrect Misconceptions

Lesson

3357

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1180

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CRISPR/Cas9 in yeast: a multi-week laboratory exercise for undergraduate students

Providing undergraduate life-science students with a course-based research experience that utilizes cutting-edge technology, is tractable for students, and is manageable as an instructor is a challenge. Here, I describe a multi-week lesson plan...

Courses: Biochemistry and Molecular Biology Bioinformatics Genetics Microbiology Science Process Skills

bioinformaticsPCRphenotypingCRISPR/Cas9gene editingcloningGenotypingRestriction enzyme

LessonPlus

1648

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347

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Keep It Shrimple: An Adaptable Student-Driven Research Project for the Introductory Biology Laboratory

A challenge in introductory biology laboratory courses is to provide students with authentic, engaging research opportunities that allow them to take ownership of their experiments. We present a nine-week introductory biology module that allows...

Courses: Introductory Biology Science Process Skills

hypothesis testingexperimental designanimal behaviorbrine shrimp

Lesson

3648

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3315

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Using CRISPR-Cas9 to teach the fundamentals of molecular biology and experimental design

One of the challenges of inquiry-based research experiences is balancing the instruction on skills and techniques with data generation and analysis. This is especially true in technique heavy disciplines such as molecular biology, where emphasis...

Courses: Biochemistry and Molecular Biology

experimental designcrisprmolecular technique

Lesson

2141

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496

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Necessary and Sufficient? Solving the Mystery of the Mitochondrial Pyruvate Transporter

While there are several available lessons for teaching introductory biology students about diffusion, facilitated diffusion, and active transport, fewer materials exist to support upper-division students' understanding of the proteins that...

Courses: Cell Biology

DiffusionActive transportfacilitated diffusionNecessary and sufficientTransport proteins

Lesson

2708

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83

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An Inquiry-Based Project Added to Traditional Labs: Hands-On Fish Awareness Research in Freshwater Systems Conducted by First-Year Biology Students

This project involves students in an inquiry-based project added to the introductory biology laboratory course for majors in fall 2019. Research has shown that student engagement in authentic research has significant positive impacts on...

Courses: Introductory Biology Science Process Skills

Evolutionbehaviorichthyology

Lesson

1280

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169

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Central Dogma, Dictionaries, and Functions: Using Programming Concepts to Simulate Biological Processes

Technologies like next-generation sequencing, proteomics, and high-throughput phenotyping have transformed the way we do biology. There is a continued need for scientists with computational skills to analyze biological data while understanding the...

Courses: Bioinformatics

computationpythonJupyter notebookFunctionscentral dogmaDictionaries

Lesson

1249

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65

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Defining Life: Exploring Creativity, Scientific Discovery, and Biology Core Concepts in a Disciplinary First-Year Seminar

This unit, Defining Life, engages students in thinking like scientists, applying creativity to science, and learning biology core concepts as they explore the defining characteristics of life. This unit provides an example of a curriculum designed...

Courses: Biochemistry and Molecular Biology Cell Biology Evolution Genetics Introductory Biology Microbiology Science Process Skills

Evolutionbiologycellprocess of science

Teaching Tools and Strategies

3637

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1718

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A 360˚ View of COVID-19

In March 2020, institutions underwent a massive transition to distance learning as a result of the COVID-19 pandemic. With so little time to devise new materials to maximize learning in the new virtual environment, instructors devised a variety of...

Courses: Biochemistry and Molecular Biology Bioinformatics Cell Biology Evolution Genetics Immunology Introductory Biology Microbiology Science Process Skills

geneticsImmunologyBiochemistrybioinformaticsmolecular evolutionpublic healthvirusCOVID19

Lesson

6437

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4115

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CURE-all: Large Scale Implementation of Authentic DNA Barcoding Research into First-Year Biology Curriculum

Growing calls in science education reform have emphasized wide-scale engagement of first-year undergraduate students in authentic research experiences; however, large course enrollments, inadequate student experience, limited resources and...

Courses: Biochemistry and Molecular Biology Bioinformatics Ecology Ecology Evolution Genetics Introductory Biology Science Process Skills

phylogeneticsbioinformaticsBiodiversityprocess of sciencetaxonomyPCRDNADNA sequencegel electrophoresis

Lesson

1729

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422

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How to Find a Gene: Retrieving Information From Gene Databases

A strong understanding of distinct gene components and the ability to retrieve relevant information from gene databases are necessary to answer a diverse set of biological questions. However, often there is a considerable gap between...

Courses: Biochemistry and Molecular Biology Bioinformatics Cell Biology Genetics Introductory Biology

NCBItranscriptiontranslationGene StructureGene databasesEnsembl

Lesson

1774

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130

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Snail Races: An Inquiry-Based Approach to Learn Invasive Species Ecology

Inquiry-based lessons allow learning that is hands-on and student-driven, fostering engagement and retention of knowledge in any discipline. Here, we use this learning framework to engage students in exploring the effects of biotic and abiotic...

Courses: Ecology Ecology

ecologyenvironmentInvasive SpeciesScience CommunicationScientific InquiryDispersal

Lesson

237

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21

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Protein Import Into the ER: Understanding Experimental Methods for Old and New Cellular Discoveries

Process Oriented Guided Inquiry Learning (POGIL) is an effective approach for group work in STEM courses. POGIL-style lessons foster active learning because they require students to communicate and co-construct knowledge to solve problems. Here,...

Courses: Cell Biology Science Process Skills

Necessary and sufficientsignal sequenceProtein SynthesistrafficER importTranslocation

Lesson

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A CURE for Salmonella: A Laboratory Course in Pathogen Microbiology and Genomics

Rapid advances in genomics and bioinformatics, the vast amount of data generated by next-generation sequencing, and the penetration of the ‘-omics’ into many areas of biology have created a need for students with hands-on experience with...

Courses: Biochemistry and Molecular Biology Bioinformatics Ecology Ecology Microbiology

epidemiologyresearchbioinformaticsgenomicspublic healthAntibiotic Resistant BacteriaSalmonellaDNA sequencingpathogenic bacteria

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525

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Doctor in the House: Improving Undergraduate Critical Thinking Skills Through Diagnosing Medical Case Studies

Students in undergraduate anatomy and physiology courses are not often exposed to clinical examples of homeostatic imbalances, particularly ones that provide an opportunity to diagnose a medical case. We designed a set of medical cases...

Courses: Anatomy-Physiology Science Process Skills

medicinediagnosiscardiovasculardeductive reasoningdigestiveEndocrinehomeostatic imbalancehypothetico-deductive modelurinary

Lesson

2663

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626

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Learning About Protein Localization: A Lesson for Analyzing Figures in a Scientific Publication

In order to function correctly, proteins must be localized to a specific subcellular location. We have designed this lesson to use data from the primary literature to teach students about the mechanisms cells use to direct proteins to the...

Courses: Cell Biology Science Process Skills

colocalizationimmunofluorescenceProtein localizationsignal sequencessubcellular fractionationwestern blotting

Lesson

1538

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Data Analysis Recitation Activities Support Better Understanding in SEA-PHAGES CURE

Course-based undergraduate research experiences (CUREs) are widely known to improve student learning outcomes in the sciences. Undergraduate students have a particularly difficult time interpreting the scientific data that they generate in these...

Courses: Science Process Skills

bacteriophageDNA extractionGel analysisPhage purificationTiter calculationViral replicative growth

Lesson

2798

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702

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Teaching Biodiversity with Museum Specimens in an Inquiry-Based Lab

In response to the growth of biology datasets and broad efforts to digitize data, an increasingly important skill for science students is the management and analysis of large datasets. We designed an inquiry-based lab module to introduce students...

Courses: Ecology Ecology Evolution Introductory Biology Science Process Skills

data analysisnatural historyphylogenyBiodiversitymammalsAllen's RuleBergmann's Ruleecogeographymuseum research

Lesson

2679

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229

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Role of Crop Genetic Diversity on Pathogen Impact: The Tale of Two Pathogens

Introductory genetics courses are part of the core curriculum in many different fields, including plant breeding, animal science, biology, microbiology, and natural resource management. Concepts involving genes, inheritance, evolution, and genome...

Courses: Introductory Biology Plant Biology Science Process Skills

plant pathologygenetic diversityDisease TriangleModes of Reproduction

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A Short Laboratory Module to Help Infuse Metacognition during an Introductory Course-based Research Experience

A How to Guide and Template for Designing a Puzzle Based Escape Room Game

CRISPR/Cas9 in yeast: a multi-week laboratory exercise for undergraduate students

Keep It Shrimple: An Adaptable Student-Driven Research Project for the Introductory Biology Laboratory

Using CRISPR-Cas9 to teach the fundamentals of molecular biology and experimental design

Necessary and Sufficient? Solving the Mystery of the Mitochondrial Pyruvate Transporter

An Inquiry-Based Project Added to Traditional Labs: Hands-On Fish Awareness Research in Freshwater Systems Conducted by First-Year Biology Students

Central Dogma, Dictionaries, and Functions: Using Programming Concepts to Simulate Biological Processes

Defining Life: Exploring Creativity, Scientific Discovery, and Biology Core Concepts in a Disciplinary First-Year Seminar

A 360˚ View of COVID-19

CURE-all: Large Scale Implementation of Authentic DNA Barcoding Research into First-Year Biology Curriculum

How to Find a Gene: Retrieving Information From Gene Databases

Snail Races: An Inquiry-Based Approach to Learn Invasive Species Ecology

Protein Import Into the ER: Understanding Experimental Methods for Old and New Cellular Discoveries

A CURE for Salmonella: A Laboratory Course in Pathogen Microbiology and Genomics

Doctor in the House: Improving Undergraduate Critical Thinking Skills Through Diagnosing Medical Case Studies

Learning About Protein Localization: A Lesson for Analyzing Figures in a Scientific Publication

Data Analysis Recitation Activities Support Better Understanding in SEA-PHAGES CURE

Teaching Biodiversity with Museum Specimens in an Inquiry-Based Lab

Role of Crop Genetic Diversity on Pathogen Impact: The Tale of Two Pathogens

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